An analysis pipeline for FAIRE-seq data

Sites across eukaryotic genomes, where disturbance or eviction of nucleosomes from chromatin takes effect, are highly correlated with the presence of active regulatory elements. Formaldehyde-assisted isolation of regulatory elements coupled with high-throughput sequencing (FAIRE-seq) has been proven...

Full description

Autores:
Urbina Gómez, David Alejandro
Tipo de recurso:
Fecha de publicación:
2012
Institución:
Universidad de los Andes
Repositorio:
Séneca: repositorio Uniandes
Idioma:
eng
OAI Identifier:
oai:repositorio.uniandes.edu.co:1992/11890
Acceso en línea:
http://hdl.handle.net/1992/11890
Palabra clave:
Biología molecular - Investigaciones
Factores de transcripción - Investigaciones
Genómica funcional - Investigaciones
Biología
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-sa/4.0/
id UNIANDES2_e91bb658dce29f0a42739919e5e7c8ea
oai_identifier_str oai:repositorio.uniandes.edu.co:1992/11890
network_acronym_str UNIANDES2
network_name_str Séneca: repositorio Uniandes
repository_id_str
spelling Al consultar y hacer uso de este recurso, está aceptando las condiciones de uso establecidas por los autores.http://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Riaño Pachón, Diego Mauricio1a797f24-d6f0-4fd6-88db-fb6145eaedc2600Urbina Gómez, David Alejandrof871a5a0-44a8-4d60-a5f8-d8cf879dd5cc6002018-09-28T08:20:06Z2018-09-28T08:20:06Z2012http://hdl.handle.net/1992/11890u627822.pdfinstname:Universidad de los Andesreponame:Repositorio Institucional Sénecarepourl:https://repositorio.uniandes.edu.co/Sites across eukaryotic genomes, where disturbance or eviction of nucleosomes from chromatin takes effect, are highly correlated with the presence of active regulatory elements. Formaldehyde-assisted isolation of regulatory elements coupled with high-throughput sequencing (FAIRE-seq) has been proven successful insolating those genomic regions. FAIRE-seq identified regions agree with results obtained using nuclease hypersensitivity or chromatin immunoprecipitation. Furthermore, FAIRE-seq increases the reproducibility of experiments because it is independent on the use of enzymes and antibodies. However, several computational analyses are required for the interpretation on genome-wide results. Also, FAIRE-seq represents challenges related with its signal characteristics.Magíster en BiologíaMaestría28 hojasapplication/pdfengUniandesMaestría en Ciencias BiológicasFacultad de CienciasDepartamento de Biologíainstname:Universidad de los Andesreponame:Repositorio Institucional SénecaAn analysis pipeline for FAIRE-seq dataTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesishttp://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/TMBiología molecular - InvestigacionesFactores de transcripción - InvestigacionesGenómica funcional - InvestigacionesBiologíaPublicationTEXTu627822.pdf.txtu627822.pdf.txtExtracted texttext/plain49105https://repositorio.uniandes.edu.co/bitstreams/e46914c2-a959-4d2c-8a63-8cb07b0afe90/download549188efb370bcca4cc1f344a9d3f210MD54ORIGINALu627822.pdfapplication/pdf5046272https://repositorio.uniandes.edu.co/bitstreams/c6481729-179f-4700-9fea-1920d479007e/download91749c2ee59f63060bd4d20771dba325MD51THUMBNAILu627822.pdf.jpgu627822.pdf.jpgIM Thumbnailimage/jpeg17877https://repositorio.uniandes.edu.co/bitstreams/db443732-c3d4-4c5b-8da8-07088061c912/downloadb11a20e3a4905bd0aed1751763f46a23MD551992/11890oai:repositorio.uniandes.edu.co:1992/118902023-10-10 19:56:35.91http://creativecommons.org/licenses/by-nc-sa/4.0/open.accesshttps://repositorio.uniandes.edu.coRepositorio institucional Sénecaadminrepositorio@uniandes.edu.co
dc.title.es_CO.fl_str_mv An analysis pipeline for FAIRE-seq data
title An analysis pipeline for FAIRE-seq data
spellingShingle An analysis pipeline for FAIRE-seq data
Biología molecular - Investigaciones
Factores de transcripción - Investigaciones
Genómica funcional - Investigaciones
Biología
title_short An analysis pipeline for FAIRE-seq data
title_full An analysis pipeline for FAIRE-seq data
title_fullStr An analysis pipeline for FAIRE-seq data
title_full_unstemmed An analysis pipeline for FAIRE-seq data
title_sort An analysis pipeline for FAIRE-seq data
dc.creator.fl_str_mv Urbina Gómez, David Alejandro
dc.contributor.advisor.none.fl_str_mv Riaño Pachón, Diego Mauricio
dc.contributor.author.none.fl_str_mv Urbina Gómez, David Alejandro
dc.subject.keyword.es_CO.fl_str_mv Biología molecular - Investigaciones
Factores de transcripción - Investigaciones
Genómica funcional - Investigaciones
topic Biología molecular - Investigaciones
Factores de transcripción - Investigaciones
Genómica funcional - Investigaciones
Biología
dc.subject.themes.none.fl_str_mv Biología
description Sites across eukaryotic genomes, where disturbance or eviction of nucleosomes from chromatin takes effect, are highly correlated with the presence of active regulatory elements. Formaldehyde-assisted isolation of regulatory elements coupled with high-throughput sequencing (FAIRE-seq) has been proven successful insolating those genomic regions. FAIRE-seq identified regions agree with results obtained using nuclease hypersensitivity or chromatin immunoprecipitation. Furthermore, FAIRE-seq increases the reproducibility of experiments because it is independent on the use of enzymes and antibodies. However, several computational analyses are required for the interpretation on genome-wide results. Also, FAIRE-seq represents challenges related with its signal characteristics.
publishDate 2012
dc.date.issued.none.fl_str_mv 2012
dc.date.accessioned.none.fl_str_mv 2018-09-28T08:20:06Z
dc.date.available.none.fl_str_mv 2018-09-28T08:20:06Z
dc.type.spa.fl_str_mv Trabajo de grado - Maestría
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.content.spa.fl_str_mv Text
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/TM
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/1992/11890
dc.identifier.pdf.none.fl_str_mv u627822.pdf
dc.identifier.instname.spa.fl_str_mv instname:Universidad de los Andes
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Séneca
dc.identifier.repourl.spa.fl_str_mv repourl:https://repositorio.uniandes.edu.co/
url http://hdl.handle.net/1992/11890
identifier_str_mv u627822.pdf
instname:Universidad de los Andes
reponame:Repositorio Institucional Séneca
repourl:https://repositorio.uniandes.edu.co/
dc.language.iso.es_CO.fl_str_mv eng
language eng
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.coar.spa.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.extent.es_CO.fl_str_mv 28 hojas
dc.format.mimetype.es_CO.fl_str_mv application/pdf
dc.publisher.es_CO.fl_str_mv Uniandes
dc.publisher.program.es_CO.fl_str_mv Maestría en Ciencias Biológicas
dc.publisher.faculty.es_CO.fl_str_mv Facultad de Ciencias
dc.publisher.department.es_CO.fl_str_mv Departamento de Biología
dc.source.es_CO.fl_str_mv instname:Universidad de los Andes
reponame:Repositorio Institucional Séneca
instname_str Universidad de los Andes
institution Universidad de los Andes
reponame_str Repositorio Institucional Séneca
collection Repositorio Institucional Séneca
bitstream.url.fl_str_mv https://repositorio.uniandes.edu.co/bitstreams/e46914c2-a959-4d2c-8a63-8cb07b0afe90/download
https://repositorio.uniandes.edu.co/bitstreams/c6481729-179f-4700-9fea-1920d479007e/download
https://repositorio.uniandes.edu.co/bitstreams/db443732-c3d4-4c5b-8da8-07088061c912/download
bitstream.checksum.fl_str_mv 549188efb370bcca4cc1f344a9d3f210
91749c2ee59f63060bd4d20771dba325
b11a20e3a4905bd0aed1751763f46a23
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositorio institucional Séneca
repository.mail.fl_str_mv adminrepositorio@uniandes.edu.co
_version_ 1812134080402161664

Publicaciones similares