Metal complexes as a possible anticancer therapy: a review of the literature
Cancer is still one of the groups of multifactorial diseases that causes more deaths worldwide. In fact, emerging resistance to traditional cancer treatments make necessary the analysis of new methods to treat cancer. One of the most successful therapies to handle cancer is the use of metallic compl...
- Autores:
-
Zuluaga Pineda, Laura Bibiana
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2021
- Institución:
- Universidad de los Andes
- Repositorio:
- Séneca: repositorio Uniandes
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.uniandes.edu.co:1992/51241
- Acceso en línea:
- http://hdl.handle.net/1992/51241
- Palabra clave:
- Cáncer
Complejos metálicos
Microbiología
Biología
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-sa/4.0/
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Al consultar y hacer uso de este recurso, está aceptando las condiciones de uso establecidas por los autores.http://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Narváez Noguera, Diana María1d771500-d274-4698-9512-364381625067600Zuluaga Pineda, Laura Bibiana9906d5e4-3fec-4891-beba-f7289f6b7c2a5002021-08-10T18:16:57Z2021-08-10T18:16:57Z2021http://hdl.handle.net/1992/5124123667.pdfinstname:Universidad de los Andesreponame:Repositorio Institucional Sénecarepourl:https://repositorio.uniandes.edu.co/Cancer is still one of the groups of multifactorial diseases that causes more deaths worldwide. In fact, emerging resistance to traditional cancer treatments make necessary the analysis of new methods to treat cancer. One of the most successful therapies to handle cancer is the use of metallic complexes, such as cisplatin. Those complexes exhibit unique characteristics, such as variable coordination modes, redox activity and reactivity against an organic substrate. In this way, the design of new metal complexes as antitumor agents has aroused great interest in the scientific community in order to obtain a better anticancer activity, reduce the overcoming secondary effects related to the low selectivity, and obtain affordable and easily accessible treatment for cancer patients.El cáncer sigue siendo uno de los grupos de enfermedades multifactoriales que causa más muertes en todo el mundo. De hecho, la resistencia emergente a los tratamientos tradicionales contra el cáncer hace necesario el análisis de nuevos métodos para tratarlo de manera eficaz. Una de las terapias más exitosas para manejar el cáncer es el uso de complejos metálicos, como el cisplatino. Estos complejos exhiben características únicas, tales como modos de coordinación variables, actividad redox y reactividad contra un sustrato orgánico. De esta forma, el diseño de nuevos complejos metálicos como agentes antitumorales ha despertado un gran interés en la comunidad científica con el fin de obtener una mejor actividad anticancerígena, reducir los efectos secundarios relacionados con la baja selectividad y obtener un tratamiento contra el cáncer asequible y de fácil acceso. pacientes.BiólogoPregrado22 hojasapplication/pdfengUniversidad de los AndesBiologíaFacultad de CienciasDepartamento de Ciencias BiológicasMetal complexes as a possible anticancer therapy: a review of the literatureTrabajo de grado - Pregradoinfo:eu-repo/semantics/bachelorThesishttp://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/TPCáncerComplejos metálicosMicrobiologíaBiología201418451PublicationTHUMBNAIL23667.pdf.jpg23667.pdf.jpgIM Thumbnailimage/jpeg9207https://repositorio.uniandes.edu.co/bitstreams/919424e7-212c-4958-8f53-9c7a9e7399c6/download47f48839f6d38627ad8fb30400b4632eMD55ORIGINAL23667.pdfapplication/pdf843760https://repositorio.uniandes.edu.co/bitstreams/92412a76-7cb1-4181-90e7-e242c9fa0141/downloadc0b7ba5a3b1c34cffe803e09982ceaf8MD51TEXT23667.pdf.txt23667.pdf.txtExtracted texttext/plain53277https://repositorio.uniandes.edu.co/bitstreams/1336ee6f-02d4-4fb4-bfb9-10a504d1e04f/download4c9a5f881e9648a88f0021aee43e94e8MD541992/51241oai:repositorio.uniandes.edu.co:1992/512412023-10-10 17:43:53.769http://creativecommons.org/licenses/by-nc-sa/4.0/open.accesshttps://repositorio.uniandes.edu.coRepositorio institucional Sénecaadminrepositorio@uniandes.edu.co |
| dc.title.spa.fl_str_mv |
Metal complexes as a possible anticancer therapy: a review of the literature |
| title |
Metal complexes as a possible anticancer therapy: a review of the literature |
| spellingShingle |
Metal complexes as a possible anticancer therapy: a review of the literature Cáncer Complejos metálicos Microbiología Biología |
| title_short |
Metal complexes as a possible anticancer therapy: a review of the literature |
| title_full |
Metal complexes as a possible anticancer therapy: a review of the literature |
| title_fullStr |
Metal complexes as a possible anticancer therapy: a review of the literature |
| title_full_unstemmed |
Metal complexes as a possible anticancer therapy: a review of the literature |
| title_sort |
Metal complexes as a possible anticancer therapy: a review of the literature |
| dc.creator.fl_str_mv |
Zuluaga Pineda, Laura Bibiana |
| dc.contributor.advisor.none.fl_str_mv |
Narváez Noguera, Diana María |
| dc.contributor.author.none.fl_str_mv |
Zuluaga Pineda, Laura Bibiana |
| dc.subject.armarc.none.fl_str_mv |
Cáncer Complejos metálicos Microbiología |
| topic |
Cáncer Complejos metálicos Microbiología Biología |
| dc.subject.themes.none.fl_str_mv |
Biología |
| description |
Cancer is still one of the groups of multifactorial diseases that causes more deaths worldwide. In fact, emerging resistance to traditional cancer treatments make necessary the analysis of new methods to treat cancer. One of the most successful therapies to handle cancer is the use of metallic complexes, such as cisplatin. Those complexes exhibit unique characteristics, such as variable coordination modes, redox activity and reactivity against an organic substrate. In this way, the design of new metal complexes as antitumor agents has aroused great interest in the scientific community in order to obtain a better anticancer activity, reduce the overcoming secondary effects related to the low selectivity, and obtain affordable and easily accessible treatment for cancer patients. |
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2021 |
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2021-08-10T18:16:57Z |
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2021 |
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