Evaluating the pyrimidine metabolism in the plant pathogen Phytophthora infestans as a target to control the late blight disease

This project studied pyrimidine metabolism in Phytophthora infestans, not only because it has been positioned as a model organism to study oomycetes, it can be grown m vitro and in vivo in potatoes and tomatoes (and some Other hosts), it has a sequenced genome and there are available methods for its...

Full description

Autores:
Garavito Diago, Manuel Fernando
Tipo de recurso:
Doctoral thesis
Fecha de publicación:
2016
Institución:
Universidad de los Andes
Repositorio:
Séneca: repositorio Uniandes
Idioma:
eng
OAI Identifier:
oai:repositorio.uniandes.edu.co:1992/7692
Acceso en línea:
http://hdl.handle.net/1992/7692
Palabra clave:
Oomicetes
Pirimidinas - Biosíntesis - Investigaciones
Papas (Tubérculos) - Enfermedades y plagas - Investigaciones
Tomates - Enfermedades y plagas - Investigaciones
Metabolismo microbiano - Investigaciones
Biología
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-sa/4.0/
Description
Summary:This project studied pyrimidine metabolism in Phytophthora infestans, not only because it has been positioned as a model organism to study oomycetes, it can be grown m vitro and in vivo in potatoes and tomatoes (and some Other hosts), it has a sequenced genome and there are available methods for its genetic transformation that allow silencing genes or to work with reporters proteins, but also, due to its historical importance in human migrations, its aggressiveness in the field, the great economic importance of crops affected (potato and tomato) and its increasingly frequent resistance to agrochemicals. The results of the Ph.D. project are presented and discussed in three separate chapters