Risk assessment in occupationally exposed populations to toxic agents - determination of genetic and epigenetic effects under oxidative stress conditions

"The research question of this thesis was: if DNA effects induced by OS associated with occupational exposure, could be used as biomarkers for early detection of high cost labor associated diseases. To address this question, the aim of the study was to characterize genetic and epigenetic effect...

Full description

Autores:
Narváez Noguera, Diana María
Tipo de recurso:
Doctoral thesis
Fecha de publicación:
2016
Institución:
Universidad de los Andes
Repositorio:
Séneca: repositorio Uniandes
Idioma:
eng
OAI Identifier:
oai:repositorio.uniandes.edu.co:1992/7747
Acceso en línea:
http://hdl.handle.net/1992/7747
Palabra clave:
Mineros - Enfermedades - Aspectos genéticos
Exposición ocupacional - Investigaciones
Biología
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-sa/4.0/
Description
Summary:"The research question of this thesis was: if DNA effects induced by OS associated with occupational exposure, could be used as biomarkers for early detection of high cost labor associated diseases. To address this question, the aim of the study was to characterize genetic and epigenetic effects of occupational exposure to coal dust and to Hg in mining activities. The data collected Will contribute to draw a perspective of contamination levels and to size effects of exposure. These results may help to establish health regulations focused on prevention, and to justify environmental policies in order to reduce the impact of exposure on Colombian miners' health..."-- Tomado de la introducción