Structural correlates of moral emotions in patients with schizophrenia

Patients with schizophrenia exhibit deficits in multiple domains of social cognition. However, no research has focused on examining moral emotions and their structural correlates in this clinical population. Therefore, the objective of this study was to investigate the neural correlates of envy and...

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Autores:
Moreno Arrieta, Daniela
Tipo de recurso:
Trabajo de grado de pregrado
Fecha de publicación:
2023
Institución:
Universidad de los Andes
Repositorio:
Séneca: repositorio Uniandes
Idioma:
eng
OAI Identifier:
oai:repositorio.uniandes.edu.co:1992/68191
Acceso en línea:
http://hdl.handle.net/1992/68191
Palabra clave:
Schizophrenia
Social cognition
Moral emotions
Envy
Schadenfreude
Structural correlates
Gray matter volume
Voxel-based morphometry
Psicología
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openAccess
License
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
id UNIANDES2_a5df64a0a0ce39ae90764428b494c94a
oai_identifier_str oai:repositorio.uniandes.edu.co:1992/68191
network_acronym_str UNIANDES2
network_name_str Séneca: repositorio Uniandes
repository_id_str
dc.title.none.fl_str_mv Structural correlates of moral emotions in patients with schizophrenia
dc.title.alternative.none.fl_str_mv Correlatos estructurales de emociones morales en pacientes con esquizofrenia
title Structural correlates of moral emotions in patients with schizophrenia
spellingShingle Structural correlates of moral emotions in patients with schizophrenia
Schizophrenia
Social cognition
Moral emotions
Envy
Schadenfreude
Structural correlates
Gray matter volume
Voxel-based morphometry
Psicología
title_short Structural correlates of moral emotions in patients with schizophrenia
title_full Structural correlates of moral emotions in patients with schizophrenia
title_fullStr Structural correlates of moral emotions in patients with schizophrenia
title_full_unstemmed Structural correlates of moral emotions in patients with schizophrenia
title_sort Structural correlates of moral emotions in patients with schizophrenia
dc.creator.fl_str_mv Moreno Arrieta, Daniela
dc.contributor.advisor.none.fl_str_mv Báez Buitrago, Sandra Jimena
dc.contributor.author.none.fl_str_mv Moreno Arrieta, Daniela
dc.contributor.jury.none.fl_str_mv Gantiva Díaz, Carlos Andrés
dc.contributor.researchgroup.es_CO.fl_str_mv Semillero de Neurociencia Social
dc.subject.keyword.none.fl_str_mv Schizophrenia
Social cognition
Moral emotions
Envy
Schadenfreude
Structural correlates
Gray matter volume
Voxel-based morphometry
topic Schizophrenia
Social cognition
Moral emotions
Envy
Schadenfreude
Structural correlates
Gray matter volume
Voxel-based morphometry
Psicología
dc.subject.themes.es_CO.fl_str_mv Psicología
description Patients with schizophrenia exhibit deficits in multiple domains of social cognition. However, no research has focused on examining moral emotions and their structural correlates in this clinical population. Therefore, the objective of this study was to investigate the neural correlates of envy and Schadenfreude (pleasure derived from the misfortune of others) in patients with schizophrenia and healthy controls. We recruited 27 patients diagnosed with schizophrenia and 38 healthy controls to complete a task designed to evoke Schadenfreude and envy. Additionally, we administered clinical and cognitive assessments to both groups. Age, sex, and premorbid intellectual level were paired between the groups. We obtained structural magnetic resonance imaging (MRI) measures from a subsample of 21 patients with schizophrenia and 27 healthy controls. Voxel-Based Morphometry was employed to explore the correlations between gray matter volumes and scores on the moral emotion test. The results revealed that patients reported significantly higher levels of envy compared to the control group. However, there were no significant differences in the experience of Schadenfreude. In patients, we observed that higher levels of envy were correlated with less gray matter volume in the middle temporal gyrus. Higher Schadenfreude scores were correlated with less grey matter volume in the postcentral gyrus, the inferior temporal gyrus and the cerebellum. These brain areas have been previously associated with social cognition, particularly mentalizing abilities. Overall, our findings contribute to a better understanding of alterations in social cognition in individuals with schizophrenia.
publishDate 2023
dc.date.accessioned.none.fl_str_mv 2023-07-06T15:13:57Z
dc.date.available.none.fl_str_mv 2023-07-06T15:13:57Z
dc.date.issued.none.fl_str_mv 2023-06-28
dc.type.es_CO.fl_str_mv Trabajo de grado - Pregrado
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/bachelorThesis
dc.type.version.none.fl_str_mv info:eu-repo/semantics/acceptedVersion
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.content.es_CO.fl_str_mv Text
dc.type.redcol.none.fl_str_mv http://purl.org/redcol/resource_type/TP
format http://purl.org/coar/resource_type/c_7a1f
status_str acceptedVersion
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/1992/68191
dc.identifier.instname.es_CO.fl_str_mv instname:Universidad de los Andes
dc.identifier.reponame.es_CO.fl_str_mv reponame:Repositorio Institucional Séneca
dc.identifier.repourl.es_CO.fl_str_mv repourl:https://repositorio.uniandes.edu.co/
url http://hdl.handle.net/1992/68191
identifier_str_mv instname:Universidad de los Andes
reponame:Repositorio Institucional Séneca
repourl:https://repositorio.uniandes.edu.co/
dc.language.iso.es_CO.fl_str_mv eng
language eng
dc.relation.references.es_CO.fl_str_mv Allen, T. A., Rueter, A. R., Abram, S. V., Brown, J. S., & DeYoung, C. G. (2017). Personality and Neural Correlates of Mentalizing Ability. European journal of personality, 31(6), 599-613. https://doi.org/10.1002/per.2133
Bigelow, N. O., Paradiso, S., Adolphs, R., Moser, D. J., Arndt, S., Heberlein, A., Nopoulos, P., & Andreasen, N. C. (2006). Perception of socially relevant stimuli in schizophrenia. Schizophrenia Research, 83(2), 257-267. https://doi.org/10.1016/j.schres.2005.12.856
Broadbelt, K., Byne, W., & Jones, L. B. (2002). Evidence for a decrease in basilar dendrites of pyramidal cells in schizophrenic medial prefrontal cortex. Schizophrenia Research, 58(1), 75-81. https://doi.org/10.1016/s0920-9964(02)00201-3
Bryant, K. L., Rogers Flattery, C. N., & Schurz, M. (2021). The Role of the Temporal Lobe in Human Social Cognition. En S. F. Brosnan & W. Wilczynski (Eds.), Cooperation and Conflict: The Interaction of Opposites in Shaping Social Behavior (pp. 104-133). Cambridge University Press. https://doi.org/10.1017/9781108671187.009
Bryden, D. W., & Roesch, M. R. (2015). Executive Control Signals in Orbitofrontal Cortex during Response Inhibition. The Journal of Neuroscience, 35(9), 3903-3914. https://doi.org/10.1523/JNEUROSCI.3587-14.2015
Burin, D. I., Jorge, R. E., Arizaga, R. A., & Paulsen, J. S. (2000). Estimation of premorbid intelligence: The word accentuation test-- Buenos Aires version. Journal of Clinical and Experimental Neuropsychology, 22(5), 677-685. https://doi.org/10.1076/1380-3395(200010)22:5;1-9;FT677
Carrington, S. J., & Bailey, A. J. (2008). Are there theory of mind regions in the brain? A review of the neuroimaging literature. Human Brain Mapping, 30(8), 2313-2335. https://doi.org/10.1002/hbm.20671
Cassetta, B., & Goghari, V. (2014). Theory of mind reasoning in schizophrenia patients and non-psychotic relatives. Psychiatry Research, 218(1), 12-19. https://doi.org/10.1016/j.psychres.2014.03.043
Chester, D. S., Powell, C. A. J., Smith, R. H., Joseph, J. E., Kedia, G., Combs, D. J. Y., & DeWall, C. N. (2013). Justice for the average Joe: The role of envy and the mentalizing network in the deservingness of others misfortunes. Social Neuroscience, 8(6), 640-649. https://doi.org/10.1080/17470919.2013.846278
Cikara, M., & Fiske, S. T. (2012). Stereotypes and Schadenfreude: Affective and Physiological Markers of Pleasure at Outgroup Misfortunes. Social Psychological and Personality Science, 3(1), 63-71. https://doi.org/10.1177/1948550611409245
Clausi, S., Olivito, G., Lupo, M., Siciliano, L., Bozzali, M., & Leggio, M. (2019). The Cerebellar Predictions for Social Interactions: Theory of Mind Abilities in Patients With Degenerative Cerebellar Atrophy. Frontiers in Cellular Neuroscience, 12. https://www.frontiersin.org/articles/10.3389/fncel.2018.00510
de Quervain, D. J.-F., Fischbacher, U., Treyer, V., Schellhammer, M., Schnyder, U., Buck, A., & Fehr, E. (2004). The neural basis of altruistic punishment. Science (New York, N.Y.), 305(5688), 1254-1258. https://doi.org/10.1126/science.1100735
Di Perna, T., Carraturo, F., Giannicola, V., Nacchia, M. A., Pepe, M., Muzii, B., Bottone, M., Sperandeo, R., Maldonato, N. M., & Scandurra, C. (2022). The Role of Envy in the Relation between Social Networking Sites Use and Depression: A Systematic Review. 59-64. Scopus. https://doi.org/10.1109/CogInfoCom55841.2022.10081751
Donohoe, G., Reilly, R., Clarke, S., Meredith, S., Green, B., Morris, D., Gill, M., Corvin, A., Garavan, H., & Robertson, I. H. (2006). Do antisaccade deficits in schizophrenia provide evidence of a specific inhibitory function? Journal of the International Neuropsychological Society: JINS, 12(6), 901-906. https://doi.org/10.1017/S135561770606108X
Ethridge, L. E., Soilleux, M., Nakonezny, P. A., Reilly, J. L., Hill, S. K., Keefe, R. S. E., Gershon, E. S., Pearlson, G. D., Tamminga, C. A., Keshavan, M. S., & Sweeney, J. A. (2014). Behavioral Response Inhibition in Psychotic Disorders: Diagnostic Specificity, Familiality and Relation to Generalized Cognitive Deficit. Schizophrenia research, 159(0), 491-498. https://doi.org/10.1016/j.schres.2014.08.025
Fliessbach, K., Weber, B., Trautner, P., Dohmen, T., Sunde, U., Elger, C. E., & Falk, A. (2007). Social comparison affects reward-related brain activity in the human ventral striatum. Science (New York, N.Y.), 318(5854), 1305-1308. https://doi.org/10.1126/science.1145876
Fulginiti, A., & Brekke, J. S. (2015). Escape from Discrepancy: Self-Esteem and Quality of Life as Predictors of Current Suicidal Ideation Among Individuals with Schizophrenia. Community Mental Health Journal, 51(6), 654-662. https://doi.org/10.1007/s10597-015-9846-8
Gao, Z., Zhao, W., Liu, S., Liu, Z., Yang, C., & Xu, Y. (2021). Facial Emotion Recognition in Schizophrenia. Frontiers in Psychiatry, 12. https://www.frontiersin.org/articles/10.3389/fpsyt.2021.633717
Gómez-Carvajal, A.-M., Santamaría-García, H., García, A. M., Valderrama, M., Mejia, J., Santamaría-García, J., Bernal, M., Silva, J., Ibáñez, A., & Baez, S. (2020). The unique social sense of puerperium: Increased empathy and Schadenfreude in parents of newborns. Scientific Reports, 10(1). Scopus. https://doi.org/10.1038/s41598-020-62622-7
Green, M. F., Penn, D. L., Bentall, R., Carpenter, W. T., Gaebel, W., Gur, R. C., Kring, A. M., Park, S., Silverstein, S. M., & Heinssen, R. (2008). Social cognition in schizophrenia: An NIMH workshop on definitions, assessment, and research opportunities. Schizophrenia Bulletin, 34(6), 1211-1220. https://doi.org/10.1093/schbul/sbm145
Gregory, A., Mallikarjun, P., & Upthegrove, R. (2017). Treatment of depression in schizophrenia: Systematic review and meta-analysis. The British Journal of Psychiatry: The Journal of Mental Science, 211(4), 198-204. https://doi.org/10.1192/bjp.bp.116.190520
Haidt, J. (2003). Elevation and the positive psychology of morality. En Flourishing: Positive psychology and the life well-lived (pp. 275-289). American Psychological Association. https://doi.org/10.1037/10594-012
Heider, F. (1958). The psychology of interpersonal relations (pp. ix, 326). John Wiley & Sons Inc. https://doi.org/10.1037/10628-000
Heleven, E., Van Dun, K., & Van Overwalle, F. (2019). The posterior Cerebellum is involved in constructing Social Action Sequences: An fMRI Study. Scientific Reports, 9(1), 11110. https://doi.org/10.1038/s41598-019-46962-7
Hirschfeld, R. M. A., Williams, J. B. W., Spitzer, R. L., Calabrese, J. R., Flynn, L., Keck, P. E., Lewis, L., McElroy, S. L., Post, R. M., Rapport, D. J., Russell, J. M., Sachs, G. S., & Zajecka, J. (2000). Development and Validation of a Screening Instrument for Bipolar Spectrum Disorder: The Mood Disorder Questionnaire. American Journal of Psychiatry, 157(11), 1873-1875. https://doi.org/10.1176/appi.ajp.157.11.1873
Hoekert, M., Kahn, R. S., Pijnenborg, M., & Aleman, A. (2007). Impaired recognition and expression of emotional prosody in schizophrenia: Review and meta-analysis. Schizophrenia Research, 96(1-3), 135-145. https://doi.org/10.1016/j.schres.2007.07.023
Hofer, A., Biedermann, F., Kaufmann, A., Kemmler, G., Pfaffenberger, N. M., & Yalcin-Siedentopf, N. (2023). Self-esteem in stabilized individuals with chronic schizophrenia: Association with residual symptoms and cognitive functioning. European Archives of Psychiatry and Clinical Neuroscience. https://doi.org/10.1007/s00406-022-01538-x
Hooker, C. I., & Knight, R. T. (2006). The role of lateral orbitofrontal cortex in the inhibitory control of emotion. En D. Zald & S. Rauch (Eds.), The Orbitofrontal Cortex (p. 0). Oxford University Press. https://doi.org/10.1093/acprof:oso/9780198565741.003.0012
Jankowski, K. F., & Takahashi, H. (2014). Cognitive neuroscience of social emotions and implications for psychopathology: Examining embarrassment, guilt, envy, and schadenfreude. Psychiatry and Clinical Neurosciences, 68(5), 319-336. https://doi.org/10.1111/pcn.12182
Javed, A., & Charles, A. (2018). The Importance of Social Cognition in Improving Functional Outcomes in Schizophrenia. Frontiers in Psychiatry, 9. https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00157
Kay, S. R., Fiszbein, A., & Opler, L. A. (1987). The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia. Schizophrenia Bulletin, 13(2), 261-276. https://doi.org/10.1093/schbul/13.2.261
Kegeles, L. S., Abi-Dargham, A., Frankle, W. G., Gil, R., Cooper, T. B., Slifstein, M., Hwang, D.-R., Huang, Y., Haber, S. N., & Laruelle, M. (2010). Increased synaptic dopamine function in associative regions of the striatum in schizophrenia. Archives of General Psychiatry, 67(3), 231-239. https://doi.org/10.1001/archgenpsychiatry.2010.10
Kirschner, M., Hager, O. M., Bischof, M., Hartmann-Riemer, M. N., Kluge, A., Seifritz, E., Tobler, P. N., & Kaiser, S. (2016). Deficits in context-dependent adaptive coding of reward in schizophrenia. Npj Schizophrenia, 2(1), 16020. https://doi.org/10.1038/npjschz.2016.20
Lin, H., & Liang, J. (2021). ERP Effects of Malicious Envy on Schadenfreude in Gain and Loss Frames. Frontiers in Human Neuroscience, 15. https://www.frontiersin.org/articles/10.3389/fnhum.2021.663055
Lizcano-Cortés, F., Rasgado-Toledo, J., Giudicessi, A., & Giordano, M. (2021). Theory of Mind and Its Elusive Structural Substrate. Frontiers in Human Neuroscience, 15. https://www.frontiersin.org/articles/10.3389/fnhum.2021.618630
McCutcheon, R. A., Reis Marques, T., & Howes, O. D. (2020). Schizophrenia-An Overview. JAMA Psychiatry, 77(2), 201-210. https://doi.org/10.1001/jamapsychiatry.2019.3360
M.D, F. J. N. (2010). Envy Theory: Perspectives on the Psychology of Envy. Rowman & Littlefield Publishers.
Miyazono, K. (2015). Delusions as harmful malfunctioning beliefs. Consciousness and Cognition, 33, 561-573. https://doi.org/10.1016/j.concog.2014.10.008
Morris, R. W., Quail, S., Griffiths, K. R., Green, M. J., & Balleine, B. W. (2015). Corticostriatal control of goal-directed action is impaired in schizophrenia. Biological Psychiatry, 77(2), 187-195. https://doi.org/10.1016/j.biopsych.2014.06.005
Nasreddine, Z. S., Phillips, N. A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., Cummings, J. L., & Chertkow, H. (2005). The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment. Journal of the American Geriatrics Society, 53(4), 695-699. https://doi.org/10.1111/j.1532-5415.2005.53221.x
Ortony, A., Clore, G. L., & Collins, A. (1988). The Cognitive Structure of Emotions. Cambridge University Press. https://doi.org/10.1017/CBO9780511571299
Otti, A., Wohlschlaeger, A. M., & Noll-Hussong, M. (2015). Is the Medial Prefrontal Cortex Necessary for Theory of Mind? PLoS ONE, 10(8), e0135912. https://doi.org/10.1371/journal.pone.0135912
Patel, K. R., Cherian, J., Gohil, K., & Atkinson, D. (2014). Schizophrenia: Overview and Treatment Options. Pharmacy and Therapeutics, 39(9), 638-645.
Santamaría-García, H., Baez, S., Reyes, P., Santamaría-García, J. A., Santacruz-Escudero, J. M., Matallana, D., Arévalo, A., Sigman, M., García, A. M., & Ibáñez, A. (2017). A lesion model of envy and Schadenfreude: Legal, deservingness and moral dimensions as revealed by neurodegeneration. Brain, 140(12), 3357-3377. Scopus. https://doi.org/10.1093/brain/awx269
Schurz, M., Radua, J., Aichhorn, M., Richlan, F., & Perner, J. (2014). Fractionating theory of mind: A meta-analysis of functional brain imaging studies. Neuroscience & Biobehavioral Reviews, 42, 9-34. https://doi.org/10.1016/j.neubiorev.2014.01.009
Shamay-Tsoory, S. G., Tibi-Elhanany, Y., & Aharon-Peretz, J. (2007). The green-eyed monster and malicious joy: The neuroanatomical bases of envy and gloating (schadenfreude). Brain: A Journal of Neurology, 130(Pt 6), 1663-1678. https://doi.org/10.1093/brain/awm093
Sorg, C., Manoliu, A., Neufang, S., Myers, N., Peters, H., Schwerthöffer, D., Scherr, M., Mühlau, M., Zimmer, C., Drzezga, A., Förstl, H., Bäuml, J., Eichele, T., Wohlschläger, A. M., & Riedl, V. (2013). Increased Intrinsic Brain Activity in the Striatum Reflects Symptom Dimensions in Schizophrenia. Schizophrenia Bulletin, 39(2), 387-395. https://doi.org/10.1093/schbul/sbr184
Soyka, M. (1995). Prevalence of delusional jealousy in schizophrenia. Psychopathology, 28(2), 118-120. https://doi.org/10.1159/000284909
Soyka, M., & Schmidt, P. (2011). Prevalence of delusional jealousy in psychiatric disorders. Journal of Forensic Sciences, 56(2), 450-452. https://doi.org/10.1111/j.1556-4029.2010.01664.x
Strauss, G. P., Waltz, J. A., & Gold, J. M. (2014). A Review of Reward Processing and Motivational Impairment in Schizophrenia. Schizophrenia Bulletin, 40(Suppl_2), S107-S116. https://doi.org/10.1093/schbul/sbt197
Sun, Q., Fang, Y., Shi, Y., Wang, L., Peng, X., & Tan, L. (2021). Inhibitory Top-Down Control Deficits in Schizophrenia With Auditory Verbal Hallucinations: A Go/NoGo Task. Frontiers in Psychiatry, 12, 544746. https://doi.org/10.3389/fpsyt.2021.544746
Szeszko, P. R., Bilder, R. M., Lencz, T., Ashtari, M., Goldman, R. S., Reiter, G., Wu, H., & Lieberman, J. A. (2000). Reduced anterior cingulate gyrus volume correlates with executive dysfunction in men with first-episode schizophrenia. Schizophrenia Research, 43(2-3), 97-108. https://doi.org/10.1016/s0920-9964(99)00155-3
Takahashi, H., Kato, M., Matsuura, M., Mobbs, D., Suhara, T., & Okubo, Y. (2009a). When your gain is my pain and your pain is my gain: Neural correlates of envy and schadenfreude. Science (New York, N.Y.), 323(5916), 937-939. https://doi.org/10.1126/science.1165604
Takahashi, H., Kato, M., Matsuura, M., Mobbs, D., Suhara, T., & Okubo, Y. (2009b). When Your Gain Is My Pain and Your Pain Is My Gain: Neural Correlates of Envy and Schadenfreude. Science, 323(5916), 937-939. https://doi.org/10.1126/science.1165604
Todtenkopf, M. S., Vincent, S. L., & Benes, F. M. (2005). A cross-study meta-analysis and three-dimensional comparison of cell counting in the anterior cingulate cortex of schizophrenic and bipolar brain. Schizophrenia Research, 73(1), 79-89. https://doi.org/10.1016/j.schres.2004.08.018
Torralva, T., Roca, M., Gleichgerrcht, E., Bekinschtein, T., & Manes, F. (2009). A neuropsychological battery to detect specific executive and social cognitive impairments in early frontotemporal dementia. Brain, 132(5), 1299-1309. https://doi.org/10.1093/brain/awp041
Tricomi, E., Rangel, A., Camerer, C. F., & O'Doherty, J. P. (2010). Neural evidence for inequality-averse social preferences. Nature, 463(7284), 1089-1091. https://doi.org/10.1038/nature08785
Upthegrove, R., Marwaha, S., & Birchwood, M. (2017). Depression and Schizophrenia: Cause, Consequence, or Trans-diagnostic Issue? Schizophrenia Bulletin, 43(2), 240-244. https://doi.org/10.1093/schbul/sbw097
Van Dijk, W. W., Ouwerkerk, J. W., Goslinga, S., & Nieweg, M. (2005). Deservingness and Schadenfreude. Cognition and Emotion, 19, 933-939. https://doi.org/10.1080/02699930541000066
Van Overwalle, F., Manto, M., Cattaneo, Z., Clausi, S., Ferrari, C., Gabrieli, J. D. E., Guell, X., Heleven, E., Lupo, M., Ma, Q., Michelutti, M., Olivito, G., Pu, M., Rice, L. C., Schmahmann, J. D., Siciliano, L., Sokolov, A. A., Stoodley, C. J., van Dun, K., Leggio, M. (2020). Consensus Paper: Cerebellum and Social Cognition. Cerebellum (London, England), 19(6), 833-868. https://doi.org/10.1007/s12311-020-01155-1
Vucurovic, K., Raucher-Chéné, D., Obert, A., Gobin, P., Henry, A., Barrière, S., Traykova, M., Gierski, F., Portefaix, C., Caillies, S., & Kaladjian, A. (2023). Activation of the left medial temporal gyrus and adjacent brain areas during affective theory of mind processing correlates with trait schizotypy in a nonclinical population. Social Cognitive and Affective Neuroscience, 18(1), nsac051. https://doi.org/10.1093/scan/nsac051
Wechsler, D. (1955). Manual for the Wechsler Adult Intelligence Scale (pp. vi, 110). Psychological Corp.
Xiang, Y., Dong, X., & Zhao, J. (2020). Effects of Envy on Depression: The Mediating Roles of Psychological Resilience and Social Support. Psychiatry Investigation, 17(6), 547-555. https://doi.org/10.30773/pi.2019.0266
Yoo, T., Kim, S.-W., Kim, S.-Y., Lee, J.-Y., Kang, H.-J., Bae, K.-Y., Kim, J.-M., Shin, I.-S., & Yoon, J.-S. (2015). Relationship between Suicidality and Low Self-esteem in Patients with Schizophrenia. Clinical Psychopharmacology and Neuroscience: The Official Scientific Journal of the Korean College of Neuropsychopharmacology, 13(3), 296-301. https://doi.org/10.9758/cpn.2015.13.3.296
Zahn, R., Moll, J., Krueger, F., Huey, E. D., Garrido, G., & Grafman, J. (2007). Social concepts are represented in the superior anterior temporal cortex. Proceedings of the National Academy of Sciences, 104(15), 6430-6435. https://doi.org/10.1073/pnas.0607061104
Zhuang, Q., Xu, L., Zhou, F., Yao, S., Zheng, X., Zhou, X., Li, J., Xu, X., Fu, M., Li, K., Vatansever, D., Kendrick, K. M., & Becker, B. (2021). Segregating domain-general from emotional context-specific inhibitory control systems Ventral striatum and orbitofrontal cortex serve as emotion-cognition integration hubs. NeuroImage, 238, 118269. https://doi.org/10.1016/j.neuroimage.2021.118269
Ashburner, J., & Friston, K. J. (2000). Voxel-Based Morphometry The Methods. NeuroImage, 11(6), 805-821. https://doi.org/10.1006/nimg.2000.0582
Baez, S., Pino, M., Berrío, M., Santamaría-García, H., Sedeño, L., García, A. M., Fittipaldi, S., & Ibáñez, A. (2018). Corticostriatal signatures of schadenfreude: Evidence from Huntington's disease. Journal of Neurology, Neurosurgery and Psychiatry, 89(1), 112-116. Scopus. https://doi.org/10.1136/jnnp-2017-316055
Baez, S., Santamaría-García, H., Orozco, J., Fittipaldi, S., García, A. M., Pino, M., & Ibáñez, A. (2016). Your misery is no longer my pleasure: Reduced schadenfreude in Huntington's disease families. Cortex, 83, 78-85. https://doi.org/10.1016/j.cortex.2016.07.009
Beck Depression Inventory-II. (s. f.). Recuperado 13 de junio de 2023, de https://psycnet.apa.org/doiLanding?doi=10.1037%2Ft00742-000
Bell, C. C. (1994). DSM-IV: Diagnostic and Statistical Manual of Mental Disorders. JAMA, 272(10), 828-829. https://doi.org/10.1001/jama.1994.03520100096046
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dc.publisher.faculty.es_CO.fl_str_mv Facultad de Ciencias Sociales
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spelling Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Báez Buitrago, Sandra Jimenavirtual::8594-1Moreno Arrieta, Daniela503f966d-c5ba-44bc-982d-1cd0dbbb0531600Gantiva Díaz, Carlos AndrésSemillero de Neurociencia Social2023-07-06T15:13:57Z2023-07-06T15:13:57Z2023-06-28http://hdl.handle.net/1992/68191instname:Universidad de los Andesreponame:Repositorio Institucional Sénecarepourl:https://repositorio.uniandes.edu.co/Patients with schizophrenia exhibit deficits in multiple domains of social cognition. However, no research has focused on examining moral emotions and their structural correlates in this clinical population. Therefore, the objective of this study was to investigate the neural correlates of envy and Schadenfreude (pleasure derived from the misfortune of others) in patients with schizophrenia and healthy controls. We recruited 27 patients diagnosed with schizophrenia and 38 healthy controls to complete a task designed to evoke Schadenfreude and envy. Additionally, we administered clinical and cognitive assessments to both groups. Age, sex, and premorbid intellectual level were paired between the groups. We obtained structural magnetic resonance imaging (MRI) measures from a subsample of 21 patients with schizophrenia and 27 healthy controls. Voxel-Based Morphometry was employed to explore the correlations between gray matter volumes and scores on the moral emotion test. The results revealed that patients reported significantly higher levels of envy compared to the control group. However, there were no significant differences in the experience of Schadenfreude. In patients, we observed that higher levels of envy were correlated with less gray matter volume in the middle temporal gyrus. Higher Schadenfreude scores were correlated with less grey matter volume in the postcentral gyrus, the inferior temporal gyrus and the cerebellum. These brain areas have been previously associated with social cognition, particularly mentalizing abilities. Overall, our findings contribute to a better understanding of alterations in social cognition in individuals with schizophrenia.PsicólogoPregrado38 páginasapplication/pdfengUniversidad de los AndesPsicologíaFacultad de Ciencias SocialesDepartamento de PsicologíaStructural correlates of moral emotions in patients with schizophreniaCorrelatos estructurales de emociones morales en pacientes con esquizofreniaTrabajo de grado - Pregradoinfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_7a1fTexthttp://purl.org/redcol/resource_type/TPSchizophreniaSocial cognitionMoral emotionsEnvySchadenfreudeStructural correlatesGray matter volumeVoxel-based morphometryPsicologíaAllen, T. A., Rueter, A. R., Abram, S. V., Brown, J. S., & DeYoung, C. G. (2017). Personality and Neural Correlates of Mentalizing Ability. European journal of personality, 31(6), 599-613. https://doi.org/10.1002/per.2133Bigelow, N. O., Paradiso, S., Adolphs, R., Moser, D. J., Arndt, S., Heberlein, A., Nopoulos, P., & Andreasen, N. C. (2006). Perception of socially relevant stimuli in schizophrenia. Schizophrenia Research, 83(2), 257-267. https://doi.org/10.1016/j.schres.2005.12.856Broadbelt, K., Byne, W., & Jones, L. B. (2002). Evidence for a decrease in basilar dendrites of pyramidal cells in schizophrenic medial prefrontal cortex. Schizophrenia Research, 58(1), 75-81. https://doi.org/10.1016/s0920-9964(02)00201-3Bryant, K. L., Rogers Flattery, C. N., & Schurz, M. (2021). The Role of the Temporal Lobe in Human Social Cognition. En S. F. Brosnan & W. Wilczynski (Eds.), Cooperation and Conflict: The Interaction of Opposites in Shaping Social Behavior (pp. 104-133). Cambridge University Press. https://doi.org/10.1017/9781108671187.009Bryden, D. W., & Roesch, M. R. (2015). Executive Control Signals in Orbitofrontal Cortex during Response Inhibition. The Journal of Neuroscience, 35(9), 3903-3914. https://doi.org/10.1523/JNEUROSCI.3587-14.2015Burin, D. I., Jorge, R. E., Arizaga, R. A., & Paulsen, J. S. (2000). Estimation of premorbid intelligence: The word accentuation test-- Buenos Aires version. Journal of Clinical and Experimental Neuropsychology, 22(5), 677-685. https://doi.org/10.1076/1380-3395(200010)22:5;1-9;FT677Carrington, S. J., & Bailey, A. J. (2008). Are there theory of mind regions in the brain? A review of the neuroimaging literature. Human Brain Mapping, 30(8), 2313-2335. https://doi.org/10.1002/hbm.20671Cassetta, B., & Goghari, V. (2014). Theory of mind reasoning in schizophrenia patients and non-psychotic relatives. Psychiatry Research, 218(1), 12-19. https://doi.org/10.1016/j.psychres.2014.03.043Chester, D. S., Powell, C. A. J., Smith, R. H., Joseph, J. E., Kedia, G., Combs, D. J. Y., & DeWall, C. N. (2013). Justice for the average Joe: The role of envy and the mentalizing network in the deservingness of others misfortunes. Social Neuroscience, 8(6), 640-649. https://doi.org/10.1080/17470919.2013.846278Cikara, M., & Fiske, S. T. (2012). Stereotypes and Schadenfreude: Affective and Physiological Markers of Pleasure at Outgroup Misfortunes. Social Psychological and Personality Science, 3(1), 63-71. https://doi.org/10.1177/1948550611409245Clausi, S., Olivito, G., Lupo, M., Siciliano, L., Bozzali, M., & Leggio, M. (2019). The Cerebellar Predictions for Social Interactions: Theory of Mind Abilities in Patients With Degenerative Cerebellar Atrophy. Frontiers in Cellular Neuroscience, 12. https://www.frontiersin.org/articles/10.3389/fncel.2018.00510de Quervain, D. J.-F., Fischbacher, U., Treyer, V., Schellhammer, M., Schnyder, U., Buck, A., & Fehr, E. (2004). The neural basis of altruistic punishment. Science (New York, N.Y.), 305(5688), 1254-1258. https://doi.org/10.1126/science.1100735Di Perna, T., Carraturo, F., Giannicola, V., Nacchia, M. A., Pepe, M., Muzii, B., Bottone, M., Sperandeo, R., Maldonato, N. M., & Scandurra, C. (2022). The Role of Envy in the Relation between Social Networking Sites Use and Depression: A Systematic Review. 59-64. Scopus. https://doi.org/10.1109/CogInfoCom55841.2022.10081751Donohoe, G., Reilly, R., Clarke, S., Meredith, S., Green, B., Morris, D., Gill, M., Corvin, A., Garavan, H., & Robertson, I. H. (2006). Do antisaccade deficits in schizophrenia provide evidence of a specific inhibitory function? Journal of the International Neuropsychological Society: JINS, 12(6), 901-906. https://doi.org/10.1017/S135561770606108XEthridge, L. E., Soilleux, M., Nakonezny, P. A., Reilly, J. L., Hill, S. K., Keefe, R. S. E., Gershon, E. S., Pearlson, G. D., Tamminga, C. A., Keshavan, M. S., & Sweeney, J. A. (2014). Behavioral Response Inhibition in Psychotic Disorders: Diagnostic Specificity, Familiality and Relation to Generalized Cognitive Deficit. Schizophrenia research, 159(0), 491-498. https://doi.org/10.1016/j.schres.2014.08.025Fliessbach, K., Weber, B., Trautner, P., Dohmen, T., Sunde, U., Elger, C. E., & Falk, A. (2007). Social comparison affects reward-related brain activity in the human ventral striatum. Science (New York, N.Y.), 318(5854), 1305-1308. https://doi.org/10.1126/science.1145876Fulginiti, A., & Brekke, J. S. (2015). Escape from Discrepancy: Self-Esteem and Quality of Life as Predictors of Current Suicidal Ideation Among Individuals with Schizophrenia. Community Mental Health Journal, 51(6), 654-662. https://doi.org/10.1007/s10597-015-9846-8Gao, Z., Zhao, W., Liu, S., Liu, Z., Yang, C., & Xu, Y. (2021). Facial Emotion Recognition in Schizophrenia. Frontiers in Psychiatry, 12. https://www.frontiersin.org/articles/10.3389/fpsyt.2021.633717Gómez-Carvajal, A.-M., Santamaría-García, H., García, A. M., Valderrama, M., Mejia, J., Santamaría-García, J., Bernal, M., Silva, J., Ibáñez, A., & Baez, S. (2020). The unique social sense of puerperium: Increased empathy and Schadenfreude in parents of newborns. Scientific Reports, 10(1). Scopus. https://doi.org/10.1038/s41598-020-62622-7Green, M. F., Penn, D. L., Bentall, R., Carpenter, W. T., Gaebel, W., Gur, R. C., Kring, A. M., Park, S., Silverstein, S. M., & Heinssen, R. (2008). Social cognition in schizophrenia: An NIMH workshop on definitions, assessment, and research opportunities. Schizophrenia Bulletin, 34(6), 1211-1220. https://doi.org/10.1093/schbul/sbm145Gregory, A., Mallikarjun, P., & Upthegrove, R. (2017). Treatment of depression in schizophrenia: Systematic review and meta-analysis. The British Journal of Psychiatry: The Journal of Mental Science, 211(4), 198-204. https://doi.org/10.1192/bjp.bp.116.190520Haidt, J. (2003). Elevation and the positive psychology of morality. En Flourishing: Positive psychology and the life well-lived (pp. 275-289). American Psychological Association. https://doi.org/10.1037/10594-012Heider, F. (1958). The psychology of interpersonal relations (pp. ix, 326). John Wiley & Sons Inc. https://doi.org/10.1037/10628-000Heleven, E., Van Dun, K., & Van Overwalle, F. (2019). The posterior Cerebellum is involved in constructing Social Action Sequences: An fMRI Study. Scientific Reports, 9(1), 11110. https://doi.org/10.1038/s41598-019-46962-7Hirschfeld, R. M. A., Williams, J. B. W., Spitzer, R. L., Calabrese, J. R., Flynn, L., Keck, P. E., Lewis, L., McElroy, S. L., Post, R. M., Rapport, D. J., Russell, J. M., Sachs, G. S., & Zajecka, J. (2000). Development and Validation of a Screening Instrument for Bipolar Spectrum Disorder: The Mood Disorder Questionnaire. American Journal of Psychiatry, 157(11), 1873-1875. https://doi.org/10.1176/appi.ajp.157.11.1873Hoekert, M., Kahn, R. S., Pijnenborg, M., & Aleman, A. (2007). Impaired recognition and expression of emotional prosody in schizophrenia: Review and meta-analysis. Schizophrenia Research, 96(1-3), 135-145. https://doi.org/10.1016/j.schres.2007.07.023Hofer, A., Biedermann, F., Kaufmann, A., Kemmler, G., Pfaffenberger, N. M., & Yalcin-Siedentopf, N. (2023). Self-esteem in stabilized individuals with chronic schizophrenia: Association with residual symptoms and cognitive functioning. European Archives of Psychiatry and Clinical Neuroscience. https://doi.org/10.1007/s00406-022-01538-xHooker, C. I., & Knight, R. T. (2006). The role of lateral orbitofrontal cortex in the inhibitory control of emotion. En D. Zald & S. Rauch (Eds.), The Orbitofrontal Cortex (p. 0). Oxford University Press. https://doi.org/10.1093/acprof:oso/9780198565741.003.0012Jankowski, K. F., & Takahashi, H. (2014). Cognitive neuroscience of social emotions and implications for psychopathology: Examining embarrassment, guilt, envy, and schadenfreude. Psychiatry and Clinical Neurosciences, 68(5), 319-336. https://doi.org/10.1111/pcn.12182Javed, A., & Charles, A. (2018). The Importance of Social Cognition in Improving Functional Outcomes in Schizophrenia. Frontiers in Psychiatry, 9. https://www.frontiersin.org/articles/10.3389/fpsyt.2018.00157Kay, S. R., Fiszbein, A., & Opler, L. A. (1987). The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia. Schizophrenia Bulletin, 13(2), 261-276. https://doi.org/10.1093/schbul/13.2.261Kegeles, L. S., Abi-Dargham, A., Frankle, W. G., Gil, R., Cooper, T. B., Slifstein, M., Hwang, D.-R., Huang, Y., Haber, S. N., & Laruelle, M. (2010). Increased synaptic dopamine function in associative regions of the striatum in schizophrenia. Archives of General Psychiatry, 67(3), 231-239. https://doi.org/10.1001/archgenpsychiatry.2010.10Kirschner, M., Hager, O. M., Bischof, M., Hartmann-Riemer, M. N., Kluge, A., Seifritz, E., Tobler, P. N., & Kaiser, S. (2016). Deficits in context-dependent adaptive coding of reward in schizophrenia. Npj Schizophrenia, 2(1), 16020. https://doi.org/10.1038/npjschz.2016.20Lin, H., & Liang, J. (2021). ERP Effects of Malicious Envy on Schadenfreude in Gain and Loss Frames. Frontiers in Human Neuroscience, 15. https://www.frontiersin.org/articles/10.3389/fnhum.2021.663055Lizcano-Cortés, F., Rasgado-Toledo, J., Giudicessi, A., & Giordano, M. (2021). Theory of Mind and Its Elusive Structural Substrate. Frontiers in Human Neuroscience, 15. https://www.frontiersin.org/articles/10.3389/fnhum.2021.618630McCutcheon, R. A., Reis Marques, T., & Howes, O. D. (2020). Schizophrenia-An Overview. JAMA Psychiatry, 77(2), 201-210. https://doi.org/10.1001/jamapsychiatry.2019.3360M.D, F. J. N. (2010). Envy Theory: Perspectives on the Psychology of Envy. Rowman & Littlefield Publishers.Miyazono, K. (2015). Delusions as harmful malfunctioning beliefs. Consciousness and Cognition, 33, 561-573. https://doi.org/10.1016/j.concog.2014.10.008Morris, R. W., Quail, S., Griffiths, K. R., Green, M. J., & Balleine, B. W. (2015). Corticostriatal control of goal-directed action is impaired in schizophrenia. Biological Psychiatry, 77(2), 187-195. https://doi.org/10.1016/j.biopsych.2014.06.005Nasreddine, Z. S., Phillips, N. A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., Cummings, J. L., & Chertkow, H. (2005). The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment. Journal of the American Geriatrics Society, 53(4), 695-699. https://doi.org/10.1111/j.1532-5415.2005.53221.xOrtony, A., Clore, G. L., & Collins, A. (1988). The Cognitive Structure of Emotions. Cambridge University Press. https://doi.org/10.1017/CBO9780511571299Otti, A., Wohlschlaeger, A. M., & Noll-Hussong, M. (2015). Is the Medial Prefrontal Cortex Necessary for Theory of Mind? PLoS ONE, 10(8), e0135912. https://doi.org/10.1371/journal.pone.0135912Patel, K. R., Cherian, J., Gohil, K., & Atkinson, D. (2014). Schizophrenia: Overview and Treatment Options. Pharmacy and Therapeutics, 39(9), 638-645.Santamaría-García, H., Baez, S., Reyes, P., Santamaría-García, J. A., Santacruz-Escudero, J. M., Matallana, D., Arévalo, A., Sigman, M., García, A. M., & Ibáñez, A. (2017). A lesion model of envy and Schadenfreude: Legal, deservingness and moral dimensions as revealed by neurodegeneration. Brain, 140(12), 3357-3377. Scopus. https://doi.org/10.1093/brain/awx269Schurz, M., Radua, J., Aichhorn, M., Richlan, F., & Perner, J. (2014). Fractionating theory of mind: A meta-analysis of functional brain imaging studies. Neuroscience & Biobehavioral Reviews, 42, 9-34. https://doi.org/10.1016/j.neubiorev.2014.01.009Shamay-Tsoory, S. G., Tibi-Elhanany, Y., & Aharon-Peretz, J. (2007). The green-eyed monster and malicious joy: The neuroanatomical bases of envy and gloating (schadenfreude). Brain: A Journal of Neurology, 130(Pt 6), 1663-1678. https://doi.org/10.1093/brain/awm093Sorg, C., Manoliu, A., Neufang, S., Myers, N., Peters, H., Schwerthöffer, D., Scherr, M., Mühlau, M., Zimmer, C., Drzezga, A., Förstl, H., Bäuml, J., Eichele, T., Wohlschläger, A. M., & Riedl, V. (2013). Increased Intrinsic Brain Activity in the Striatum Reflects Symptom Dimensions in Schizophrenia. Schizophrenia Bulletin, 39(2), 387-395. https://doi.org/10.1093/schbul/sbr184Soyka, M. (1995). Prevalence of delusional jealousy in schizophrenia. Psychopathology, 28(2), 118-120. https://doi.org/10.1159/000284909Soyka, M., & Schmidt, P. (2011). Prevalence of delusional jealousy in psychiatric disorders. Journal of Forensic Sciences, 56(2), 450-452. https://doi.org/10.1111/j.1556-4029.2010.01664.xStrauss, G. P., Waltz, J. A., & Gold, J. M. (2014). A Review of Reward Processing and Motivational Impairment in Schizophrenia. Schizophrenia Bulletin, 40(Suppl_2), S107-S116. https://doi.org/10.1093/schbul/sbt197Sun, Q., Fang, Y., Shi, Y., Wang, L., Peng, X., & Tan, L. (2021). Inhibitory Top-Down Control Deficits in Schizophrenia With Auditory Verbal Hallucinations: A Go/NoGo Task. Frontiers in Psychiatry, 12, 544746. https://doi.org/10.3389/fpsyt.2021.544746Szeszko, P. R., Bilder, R. M., Lencz, T., Ashtari, M., Goldman, R. S., Reiter, G., Wu, H., & Lieberman, J. A. (2000). Reduced anterior cingulate gyrus volume correlates with executive dysfunction in men with first-episode schizophrenia. Schizophrenia Research, 43(2-3), 97-108. https://doi.org/10.1016/s0920-9964(99)00155-3Takahashi, H., Kato, M., Matsuura, M., Mobbs, D., Suhara, T., & Okubo, Y. (2009a). When your gain is my pain and your pain is my gain: Neural correlates of envy and schadenfreude. Science (New York, N.Y.), 323(5916), 937-939. https://doi.org/10.1126/science.1165604Takahashi, H., Kato, M., Matsuura, M., Mobbs, D., Suhara, T., & Okubo, Y. (2009b). When Your Gain Is My Pain and Your Pain Is My Gain: Neural Correlates of Envy and Schadenfreude. Science, 323(5916), 937-939. https://doi.org/10.1126/science.1165604Todtenkopf, M. S., Vincent, S. L., & Benes, F. M. (2005). A cross-study meta-analysis and three-dimensional comparison of cell counting in the anterior cingulate cortex of schizophrenic and bipolar brain. Schizophrenia Research, 73(1), 79-89. https://doi.org/10.1016/j.schres.2004.08.018Torralva, T., Roca, M., Gleichgerrcht, E., Bekinschtein, T., & Manes, F. (2009). A neuropsychological battery to detect specific executive and social cognitive impairments in early frontotemporal dementia. Brain, 132(5), 1299-1309. https://doi.org/10.1093/brain/awp041Tricomi, E., Rangel, A., Camerer, C. F., & O'Doherty, J. P. (2010). Neural evidence for inequality-averse social preferences. Nature, 463(7284), 1089-1091. https://doi.org/10.1038/nature08785Upthegrove, R., Marwaha, S., & Birchwood, M. (2017). Depression and Schizophrenia: Cause, Consequence, or Trans-diagnostic Issue? Schizophrenia Bulletin, 43(2), 240-244. https://doi.org/10.1093/schbul/sbw097Van Dijk, W. W., Ouwerkerk, J. W., Goslinga, S., & Nieweg, M. (2005). Deservingness and Schadenfreude. Cognition and Emotion, 19, 933-939. https://doi.org/10.1080/02699930541000066Van Overwalle, F., Manto, M., Cattaneo, Z., Clausi, S., Ferrari, C., Gabrieli, J. D. E., Guell, X., Heleven, E., Lupo, M., Ma, Q., Michelutti, M., Olivito, G., Pu, M., Rice, L. C., Schmahmann, J. D., Siciliano, L., Sokolov, A. A., Stoodley, C. J., van Dun, K., Leggio, M. (2020). Consensus Paper: Cerebellum and Social Cognition. Cerebellum (London, England), 19(6), 833-868. https://doi.org/10.1007/s12311-020-01155-1Vucurovic, K., Raucher-Chéné, D., Obert, A., Gobin, P., Henry, A., Barrière, S., Traykova, M., Gierski, F., Portefaix, C., Caillies, S., & Kaladjian, A. (2023). Activation of the left medial temporal gyrus and adjacent brain areas during affective theory of mind processing correlates with trait schizotypy in a nonclinical population. Social Cognitive and Affective Neuroscience, 18(1), nsac051. https://doi.org/10.1093/scan/nsac051Wechsler, D. (1955). Manual for the Wechsler Adult Intelligence Scale (pp. vi, 110). Psychological Corp.Xiang, Y., Dong, X., & Zhao, J. (2020). Effects of Envy on Depression: The Mediating Roles of Psychological Resilience and Social Support. Psychiatry Investigation, 17(6), 547-555. https://doi.org/10.30773/pi.2019.0266Yoo, T., Kim, S.-W., Kim, S.-Y., Lee, J.-Y., Kang, H.-J., Bae, K.-Y., Kim, J.-M., Shin, I.-S., & Yoon, J.-S. (2015). Relationship between Suicidality and Low Self-esteem in Patients with Schizophrenia. Clinical Psychopharmacology and Neuroscience: The Official Scientific Journal of the Korean College of Neuropsychopharmacology, 13(3), 296-301. https://doi.org/10.9758/cpn.2015.13.3.296Zahn, R., Moll, J., Krueger, F., Huey, E. D., Garrido, G., & Grafman, J. (2007). Social concepts are represented in the superior anterior temporal cortex. Proceedings of the National Academy of Sciences, 104(15), 6430-6435. https://doi.org/10.1073/pnas.0607061104Zhuang, Q., Xu, L., Zhou, F., Yao, S., Zheng, X., Zhou, X., Li, J., Xu, X., Fu, M., Li, K., Vatansever, D., Kendrick, K. M., & Becker, B. (2021). Segregating domain-general from emotional context-specific inhibitory control systems Ventral striatum and orbitofrontal cortex serve as emotion-cognition integration hubs. NeuroImage, 238, 118269. https://doi.org/10.1016/j.neuroimage.2021.118269Ashburner, J., & Friston, K. J. (2000). Voxel-Based Morphometry The Methods. NeuroImage, 11(6), 805-821. https://doi.org/10.1006/nimg.2000.0582Baez, S., Pino, M., Berrío, M., Santamaría-García, H., Sedeño, L., García, A. M., Fittipaldi, S., & Ibáñez, A. (2018). Corticostriatal signatures of schadenfreude: Evidence from Huntington's disease. Journal of Neurology, Neurosurgery and Psychiatry, 89(1), 112-116. Scopus. https://doi.org/10.1136/jnnp-2017-316055Baez, S., Santamaría-García, H., Orozco, J., Fittipaldi, S., García, A. M., Pino, M., & Ibáñez, A. (2016). Your misery is no longer my pleasure: Reduced schadenfreude in Huntington's disease families. Cortex, 83, 78-85. https://doi.org/10.1016/j.cortex.2016.07.009Beck Depression Inventory-II. (s. f.). Recuperado 13 de junio de 2023, de https://psycnet.apa.org/doiLanding?doi=10.1037%2Ft00742-000Bell, C. C. (1994). DSM-IV: Diagnostic and Statistical Manual of Mental Disorders. 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