Estudio del acomplejamiento de la sulfamerazina con un resorcinareno catiónico
Molecular encapsulation of antibiotics has great importance as an alternative against of bacterial resistance and carry out drug delivery. In this work was studied the molecular recognition of c-methylresorcin[4]arene tetraminomethylated with sodium sulfamerazine in aqueous solution. The results sho...
- Autores:
-
Espitia Galindo, Nicolás
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2020
- Institución:
- Universidad de los Andes
- Repositorio:
- Séneca: repositorio Uniandes
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.uniandes.edu.co:1992/51334
- Acceso en línea:
- http://hdl.handle.net/1992/51334
- Palabra clave:
- Antibióticos
Resistencia a los medicamentos
Bacterias
Química
- Rights
- openAccess
- License
- http://creativecommons.org/licenses/by-nc-sa/4.0/
| Summary: | Molecular encapsulation of antibiotics has great importance as an alternative against of bacterial resistance and carry out drug delivery. In this work was studied the molecular recognition of c-methylresorcin[4]arene tetraminomethylated with sodium sulfamerazine in aqueous solution. The results showed the formation of an inclusion complex with a 1:1 stoichiometry of c-methylresorcin[4]arene tetraminomethylated with sodium sulfamerazine. The physicochemical studies showed that the complexing process is thermodynamically favored, and the complex has great stability. This study offers a possible method for future pharmaceutical applications. |
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