Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysis
At Third P. Solutions, we are committed to advancing healthcare through the development of innovative technological solutions. This project aims to comprehensively identify and analyze the primary need that can be addressed by leveraging the strengths of our team. To achieve this goal, we conducted...
- Autores:
-
Sierra Peña, Paula Natalia
Parra Penagos, Danna Jasbleidy
García Ramírez, María Camila
Martín Lesmes, Laura Daniela
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2024
- Institución:
- Universidad de los Andes
- Repositorio:
- Séneca: repositorio Uniandes
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.uniandes.edu.co:1992/74516
- Acceso en línea:
- https://hdl.handle.net/1992/74516
- Palabra clave:
- Peritoneal dyalisis
Antimicrobial dressing
Exit site catheter infections
Biodial
Ingeniería
- Rights
- openAccess
- License
- Attribution-NonCommercial-NoDerivatives 4.0 International
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Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysis |
| title |
Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysis |
| spellingShingle |
Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysis Peritoneal dyalisis Antimicrobial dressing Exit site catheter infections Biodial Ingeniería |
| title_short |
Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysis |
| title_full |
Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysis |
| title_fullStr |
Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysis |
| title_full_unstemmed |
Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysis |
| title_sort |
Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysis |
| dc.creator.fl_str_mv |
Sierra Peña, Paula Natalia Parra Penagos, Danna Jasbleidy García Ramírez, María Camila Martín Lesmes, Laura Daniela |
| dc.contributor.advisor.none.fl_str_mv |
Briceño Triana, Juan Carlos |
| dc.contributor.author.none.fl_str_mv |
Sierra Peña, Paula Natalia Parra Penagos, Danna Jasbleidy García Ramírez, María Camila Martín Lesmes, Laura Daniela |
| dc.contributor.other.none.fl_str_mv |
Aponte Vargas, Paula Gissela |
| dc.subject.keyword.eng.fl_str_mv |
Peritoneal dyalisis Antimicrobial dressing Exit site catheter infections Biodial |
| topic |
Peritoneal dyalisis Antimicrobial dressing Exit site catheter infections Biodial Ingeniería |
| dc.subject.themes.spa.fl_str_mv |
Ingeniería |
| description |
At Third P. Solutions, we are committed to advancing healthcare through the development of innovative technological solutions. This project aims to comprehensively identify and analyze the primary need that can be addressed by leveraging the strengths of our team. To achieve this goal, we conducted an extensive information gathering process, including interviews and literature reviews, aiming to identify three critical needs for further development. Within this context, we have delved into the fundamentals of each medical condition, exploring epidemiology, anatomy, physiology, pathophysiology, clinical presentation, and economic impact. Additionally, we have conducted a detailed analysis of the key stakeholders involved in each need, ranging from patients and caregivers to healthcare service providers and funding entities. Finally, we have conducted a comprehensive market analysis to define a clear strategy that guides our research and innovation process. This analysis enables us to identify opportunities and challenges, as well as determine which need aligns most closely with our working methodology. Our findings concluded that the need that best meets most of our acceptance criteria is a way to address tunneled catheter-related infections in peritoneal dialysis patients with a novel medical device that improves infection prevention and treatment outcomes. Therefore, Third P. Solutions developed Biodial, an antimicrobial dressing that treats infections around the catheter exit site, especially the ones caused by Pseudomonas aeruginosa and Staphylococcus aureus. |
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2024 |
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2024-07-12T17:52:48Z |
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2024-07-12T17:52:48Z |
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2024-07-08 |
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Trabajo de grado - Pregrado |
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3M. (2023). Apósito 3MTM TegadermTM. 3M Ciencia Aplicable a la Vida. Recuperado de https://www.3m.com.co/3M/es_CO/p/d/b00035590/ Akoh, J. A. (2012). Peritoneal dialysis associated infections: an update on diagnosis and management. World journal of nephrology, 1(4), 106. https://doi.org/10.5527/wjn.v1.i4.106 EMODIAL. (2018). EXIT-POCKET AG. Recuperado de https://www.emodial.it/en/prodotti/exit-pocket-ag/ Facultad de Medicina. (2022). Enfermedad renal crónica (ERC), entre las de alto costo en Colombia. Universidad de los Andes. Recuperado de https://uniandes.edu.co/es/noticias/salud-y-medicina/enfermedad-renal-cronica-erc-entre-las-de-alto-costo-en-colombia Gyotoku, H., Azuma, Y., & Furuzono, T. (2020). Evaluation of fluorinated hydroxyapatite nanoparticles as an antibacterial material for catheter coating. Renal Replacement Therapy, 6, 1-8. https://doi.org/10.1186/s41100-019-0251-6 Instituto Nacional de Vigilancia de Medicamentos y Alimentos (INVIMA). (s. f.). Dispositivos médicos y equipos biomédicos. Recuperado de https://www.invima.gov.co/productos-vigilados/dispositivos-medicos/dispositivos-medicos-y-equipos-biomedicos International Organization for Standardization. (2016). Medical devices — Quality management systems — Requirements for regulatory purposes (Dispositifs médicaux — Systèmes de management de la qualité — Exigences à des fins réglementaires). (ISO 13485:2016(E), Third edition). Geneva, Switzerland. Recuperado de https://www.iso.org/home.html Jhonson & Jhonson Medical Devices. (2020). Biopatch® Protective Disk CHG. Recuperado de https://www.jnjmedtech.com/en-US/product/biopatch-protective-disk-chg Kerschbaum, J., König, P., & Rudnicki, M. (2012). Risk factors associated with peritoneal-dialysis related peritonitis. International journal of nephrology, 2012. https://doi.org/10.1155/2012/483250 Leibowitz, G. Gensini Sandra & Zavatsky Joseph (2016). Integrating Dressing Device (US8969649B2). Google Patents. https://patents.google.com/patent/US8969649B2/en Locatel. (2021). Tegaderm 6Cmx7Cm. Recuperado de Locatel. Recuperado de https://www.locatelcolombia.com/7702098400085-tegaderm-6cmx7cm/p Malkina, A. (2022). Enfermedad renal crónica (Enfermedad renal crónica; enfermedad renal crónica). MANUAL MSD. Recuperado de https://www.msdmanuals.com/es-co/professional/trastornos-urogenitales/enfermedad-renal-cr%C3%B3nica/enfermedad-renal-cr%C3%B3nica Rico-Fontalvo, J., Yama-Mosquera, E., Robayo-García, A., Aroca-Martínez, G., Arango-Álvarez, J. J., Barros-Camargo, L., & Acuna Merchán, L. (2022). Situación de la enfermedad renal crónica en Colombia. Nefrología Latinoamericana, 19(1), 79-87. https://doi.org/10.24875/NEFRO.22000030 Pecorari, G. (2009). A catheter containing device, a dressing for a catheter and a kit comprising both thereof (CA2741926C). Google Patents https://patents.google.com/patent/CA2741926C/en Pecorari, G. (2016). Antimicrobial dressing (EP2833929B1). Google Patents. https://patents.google.com/patent/EP2833929B1/en Invima. (1993). Resolución N° 8430 de 1993. Ministerio de Salud de Colombia. Recuperado de http://www.invima.gov.co/images/pdf/resoluciones/1984/r8430_1993.pdf Ministerio de Salud de Colombia. (2008). Resolución N° 2378 de 2008. Recuperado de http://www.saludcolombia.com/actual/normativi/resoluciones/res2378_2008.pdf Invima. (2010). Resolución N° 749 de 2010. Ministerio de Salud de Colombia. Recuperado de http://www.invima.gov.co/images/pdf/resoluciones/2010/r0749_2010.pdf Ministerio de Salud y Protección Social de Colombia. (2005). Resolución N° 5109 de 2005. Recuperado de http://www.suin-juriscol.gov.co/viewDocument.asp?id=1590459 Ministerio de Salud y Protección Social de Colombia. (2012). Resolución N° 683 de 2012. Recuperado de http://www.saludcolombia.com/actual/normativi/resoluciones/res0683_2012.pdf Ministerio de Salud de Colombia. (1994). Resolución N° 5262 de 1994. Recuperado de http://www.suin-juriscol.gov.co/viewDocument.asp?id=1590462 Rico-Fontalvo, J., Yama-Mosquera, E., Robayo-García, A., Aroca-Martínez, G., Arango-Álvarez, J. J., Barros-Camargo, L., & Acuna Merchán, L. (2022). Situación de la enfermedad renal crónica en Colombia. Nefrología Latinoamericana, 19, 79-87. https://doi.org/10.24875/NEFRO.22000030 Yock, P. G. et al. (2015). Biodesign: the process of innovating medical technologies. Cambridge University Press. |
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Briceño Triana, Juan Carlosvirtual::18731-1Sierra Peña, Paula NataliaParra Penagos, Danna JasbleidyGarcía Ramírez, María CamilaMartín Lesmes, Laura DanielaAponte Vargas, Paula Gissela2024-07-12T17:52:48Z2024-07-12T17:52:48Z2024-07-08https://hdl.handle.net/1992/74516instname:Universidad de los Andesreponame:Repositorio Institucional Sénecarepourl:https://repositorio.uniandes.edu.co/At Third P. Solutions, we are committed to advancing healthcare through the development of innovative technological solutions. This project aims to comprehensively identify and analyze the primary need that can be addressed by leveraging the strengths of our team. To achieve this goal, we conducted an extensive information gathering process, including interviews and literature reviews, aiming to identify three critical needs for further development. Within this context, we have delved into the fundamentals of each medical condition, exploring epidemiology, anatomy, physiology, pathophysiology, clinical presentation, and economic impact. Additionally, we have conducted a detailed analysis of the key stakeholders involved in each need, ranging from patients and caregivers to healthcare service providers and funding entities. Finally, we have conducted a comprehensive market analysis to define a clear strategy that guides our research and innovation process. This analysis enables us to identify opportunities and challenges, as well as determine which need aligns most closely with our working methodology. Our findings concluded that the need that best meets most of our acceptance criteria is a way to address tunneled catheter-related infections in peritoneal dialysis patients with a novel medical device that improves infection prevention and treatment outcomes. Therefore, Third P. Solutions developed Biodial, an antimicrobial dressing that treats infections around the catheter exit site, especially the ones caused by Pseudomonas aeruginosa and Staphylococcus aureus.Pregrado21 páginasapplication/pdfengUniversidad de los AndesIngeniería BiomédicaFacultad de IngenieríaDepartamento de Ingeniería BiomédicaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Development of an antimicrobial dressing for catheter exit site infections in peritoneal dialysisTrabajo de grado - Pregradoinfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_7a1fTexthttp://purl.org/redcol/resource_type/TPPeritoneal dyalisisAntimicrobial dressingExit site catheter infectionsBiodialIngeniería3M. (2023). Apósito 3MTM TegadermTM. 3M Ciencia Aplicable a la Vida. Recuperado de https://www.3m.com.co/3M/es_CO/p/d/b00035590/Akoh, J. A. (2012). Peritoneal dialysis associated infections: an update on diagnosis and management. World journal of nephrology, 1(4), 106. https://doi.org/10.5527/wjn.v1.i4.106EMODIAL. (2018). EXIT-POCKET AG. Recuperado de https://www.emodial.it/en/prodotti/exit-pocket-ag/Facultad de Medicina. (2022). Enfermedad renal crónica (ERC), entre las de alto costo en Colombia. Universidad de los Andes. Recuperado de https://uniandes.edu.co/es/noticias/salud-y-medicina/enfermedad-renal-cronica-erc-entre-las-de-alto-costo-en-colombiaGyotoku, H., Azuma, Y., & Furuzono, T. (2020). Evaluation of fluorinated hydroxyapatite nanoparticles as an antibacterial material for catheter coating. Renal Replacement Therapy, 6, 1-8. https://doi.org/10.1186/s41100-019-0251-6Instituto Nacional de Vigilancia de Medicamentos y Alimentos (INVIMA). (s. f.). Dispositivos médicos y equipos biomédicos. Recuperado de https://www.invima.gov.co/productos-vigilados/dispositivos-medicos/dispositivos-medicos-y-equipos-biomedicosInternational Organization for Standardization. (2016). Medical devices — Quality management systems — Requirements for regulatory purposes (Dispositifs médicaux — Systèmes de management de la qualité — Exigences à des fins réglementaires). (ISO 13485:2016(E), Third edition). Geneva, Switzerland. Recuperado de https://www.iso.org/home.htmlJhonson & Jhonson Medical Devices. (2020). Biopatch® Protective Disk CHG. Recuperado de https://www.jnjmedtech.com/en-US/product/biopatch-protective-disk-chgKerschbaum, J., König, P., & Rudnicki, M. (2012). Risk factors associated with peritoneal-dialysis related peritonitis. International journal of nephrology, 2012. https://doi.org/10.1155/2012/483250Leibowitz, G. Gensini Sandra & Zavatsky Joseph (2016). Integrating Dressing Device (US8969649B2). Google Patents. https://patents.google.com/patent/US8969649B2/enLocatel. (2021). Tegaderm 6Cmx7Cm. Recuperado de Locatel. Recuperado de https://www.locatelcolombia.com/7702098400085-tegaderm-6cmx7cm/pMalkina, A. (2022). Enfermedad renal crónica (Enfermedad renal crónica; enfermedad renal crónica). MANUAL MSD. Recuperado de https://www.msdmanuals.com/es-co/professional/trastornos-urogenitales/enfermedad-renal-cr%C3%B3nica/enfermedad-renal-cr%C3%B3nicaRico-Fontalvo, J., Yama-Mosquera, E., Robayo-García, A., Aroca-Martínez, G., Arango-Álvarez, J. J., Barros-Camargo, L., & Acuna Merchán, L. (2022). Situación de la enfermedad renal crónica en Colombia. Nefrología Latinoamericana, 19(1), 79-87. https://doi.org/10.24875/NEFRO.22000030Pecorari, G. (2009). A catheter containing device, a dressing for a catheter and a kit comprising both thereof (CA2741926C). Google Patents https://patents.google.com/patent/CA2741926C/enPecorari, G. (2016). Antimicrobial dressing (EP2833929B1). Google Patents. https://patents.google.com/patent/EP2833929B1/enInvima. (1993). Resolución N° 8430 de 1993. Ministerio de Salud de Colombia. Recuperado de http://www.invima.gov.co/images/pdf/resoluciones/1984/r8430_1993.pdfMinisterio de Salud de Colombia. (2008). Resolución N° 2378 de 2008. Recuperado de http://www.saludcolombia.com/actual/normativi/resoluciones/res2378_2008.pdfInvima. (2010). Resolución N° 749 de 2010. Ministerio de Salud de Colombia. Recuperado de http://www.invima.gov.co/images/pdf/resoluciones/2010/r0749_2010.pdfMinisterio de Salud y Protección Social de Colombia. (2005). Resolución N° 5109 de 2005. Recuperado de http://www.suin-juriscol.gov.co/viewDocument.asp?id=1590459Ministerio de Salud y Protección Social de Colombia. (2012). Resolución N° 683 de 2012. Recuperado de http://www.saludcolombia.com/actual/normativi/resoluciones/res0683_2012.pdfMinisterio de Salud de Colombia. (1994). Resolución N° 5262 de 1994. Recuperado de http://www.suin-juriscol.gov.co/viewDocument.asp?id=1590462Rico-Fontalvo, J., Yama-Mosquera, E., Robayo-García, A., Aroca-Martínez, G., Arango-Álvarez, J. J., Barros-Camargo, L., & Acuna Merchán, L. (2022). Situación de la enfermedad renal crónica en Colombia. Nefrología Latinoamericana, 19, 79-87. https://doi.org/10.24875/NEFRO.22000030Yock, P. G. et al. (2015). Biodesign: the process of innovating medical technologies. 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