Chemical synthesis and characterization of silver nanorods with various protecting agents and their antimicrobial properties against gram positive and negative bacteria

Silver nanorod suspensions were synthesized by a simple chemical soft template method. This same synthesis procedure was then modified to include a change in the protecting agent from CTAB to l-cysteine and 4-aminotiophenol. The prepared nanorods qualitatively displayed differing morphologies and sizes according to UV-Visible electronic absorption spectra and the colors of the dispersions. The effects of Ostwald ripening were evaluated on one of the nanorod suspensions so as to explain the formation of nanorods and a gradient in morphology and size for a specific temperaturas. Finally, a disk-diffusion test was performed to evaluate the antimicrobial activity of these silver nanorod dispersions. It was found that the amount of seed solution added to the growth solution in which the nanorods are synthesized greatly affects the morphology and size of these. The change in protecting agent was confirmed via UV-Vis spectroscopy. The antimicrobial assays afforded a huge activity (24.71-52.86%) for all dispersions in comparison with a positive gentamicin control at a concentration 4180x higher. The largest activity was found in the l-cysteine protected rod dispersion.

• Autores: Ardila Fernández, Santiago Andrés
• Tipo de recurso: Trabajo de grado de pregrado
• Fecha de publicación: 2023
• Institución: Universidad de los Andes
• Repositorio: Séneca: repositorio Uniandes
• Idioma: eng
• OAI Identifier: oai:repositorio.uniandes.edu.co:1992/73759
• Acceso en línea: https://hdl.handle.net/1992/73759
• Palabra clave: Nanobarras de plata; Agente protector; L-cisteína; 4-aminotiofenol; Actividad antimicrobiana; Química
• Rights: openAccess
• License: Attribution 4.0 International