Possible mechanisms of DNA demethylation in blood of patients with type 2 diabetes

"Type 2 Diabetes Mellitus (T2DM) is a complex disease characterized by hyperglycemia and increased oxidative stress that could lead to chronic micro- and macro-vascular complications. In this study, we analyze the epigenetic effects of diabetes in blood cells of patients and controls and the mo...

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Autores:
Pinzón Cortés, Jairo Arturo
Tipo de recurso:
Fecha de publicación:
2017
Institución:
Universidad de los Andes
Repositorio:
Séneca: repositorio Uniandes
Idioma:
eng
OAI Identifier:
oai:repositorio.uniandes.edu.co:1992/61097
Acceso en línea:
http://hdl.handle.net/1992/61097
Palabra clave:
ADN
Bioquímica clínica
Células sanguíneas
Diabetes
Epigenética
Estrés oxidativo
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-sa/4.0/
Description
Summary:"Type 2 Diabetes Mellitus (T2DM) is a complex disease characterized by hyperglycemia and increased oxidative stress that could lead to chronic micro- and macro-vascular complications. In this study, we analyze the epigenetic effects of diabetes in blood cells of patients and controls and the molecular causes that could originate these alterations". -- Tomado de la introducción.