Physiology, evolution and single cell gene expression : an experimental approach using a microfluidics technique

"Interest in studies about variability in gene expression has been increasing due to its applications in pharmaceutical, medical and biological sciences. Genetically identical cells can have different phenotypes even when they are growing in the same environmental conditions; this is just one o...

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Autores:
Arias Castro, Juan Carlos
Tipo de recurso:
Doctoral thesis
Fecha de publicación:
2017
Institución:
Universidad de los Andes
Repositorio:
Séneca: repositorio Uniandes
Idioma:
eng
OAI Identifier:
oai:repositorio.uniandes.edu.co:1992/61741
Acceso en línea:
http://hdl.handle.net/1992/61741
Palabra clave:
Células
Expresión génica
Fisiología celular
Microfluídica
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-sa/4.0/
Description
Summary:"Interest in studies about variability in gene expression has been increasing due to its applications in pharmaceutical, medical and biological sciences. Genetically identical cells can have different phenotypes even when they are growing in the same environmental conditions; this is just one of many examples of the consequences of stochasticity in the chemical reactions at a molecular level. In our work we try to find insights on the sources of physiology and gene expression variability and their interaction with the environment, such as the case of nutrient limitation." -- Tomado del Formato de Documento de Grado.