Effects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)

Environmental stimuli such as daily routine, dietary habits and stress are strongly related to the physiology of our body. However, we still do not know entirely how this relationship occurs. The zebrafish has been used as a promising model in behavior, stress, anxiety and neuroscience research, tha...

Full description

Autores:
Henríquez Martínez, Angie
Tipo de recurso:
Fecha de publicación:
2021
Institución:
Universidad de los Andes
Repositorio:
Séneca: repositorio Uniandes
Idioma:
eng
OAI Identifier:
oai:repositorio.uniandes.edu.co:1992/50943
Acceso en línea:
http://hdl.handle.net/1992/50943
Palabra clave:
Peces cebra
Aletas (Anatomía)
Regeneración (Biología)
Estrés postraumático
Ansiedad
Ingeniería
Rights
openAccess
License
http://creativecommons.org/licenses/by-nc-nd/4.0/
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spelling Al consultar y hacer uso de este recurso, está aceptando las condiciones de uso establecidas por los autores.http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Bloch Morel, Natasha Ivonneb751f88a-6344-4f6c-b4c3-f4f1041d3a6e400Akle Álvarez, Verónicavirtual::12764-1Henríquez Martínez, Angief420e5aa-c935-43de-8f82-56759788eb094002021-08-10T18:04:35Z2021-08-10T18:04:35Z2021http://hdl.handle.net/1992/5094323420.pdfinstname:Universidad de los Andesreponame:Repositorio Institucional Sénecarepourl:https://repositorio.uniandes.edu.co/Environmental stimuli such as daily routine, dietary habits and stress are strongly related to the physiology of our body. However, we still do not know entirely how this relationship occurs. The zebrafish has been used as a promising model in behavior, stress, anxiety and neuroscience research, thanks to its homology with vertebrates like rodents and mammals. Here in this study, we report preliminary results about the effect of chronic stress on the regeneration of the caudal fin in zebrafish (Danio rerio). We exposed fish to a UCS protocol to stimulated chronic stress conditions and performed behavioral tests (open field and light/dark preference) to evaluated anxiety-like behavior. Then we cut the lower part of the caudal fin to evaluated the effect of the stress on tissue regeneration.Desde hace unos años, el pez cebra se ha utilizado como un modelo prometedor en investigaciones sobre comportamiento, estrés, ansiedad y neurociencia, gracias a su homología con vertebrados como roedores y mamíferos, es posible recurrir a ellos como modelo biológico para estudios que tendrán impacto positivo sobre la salud y el bienestar humano y animal. En este estudio, reportamos resultados preliminares sobre el efecto del estrés crónico en la regeneración de la aleta caudal del pez cebra (Danio rerio). Durante el experimento, los peces fueron expuestos a un protocolo UCS (Unpredictabdele chronic stress) para estimular condiciones de estrés crónico. Posteriormente, se realizaron pruebas de comportamiento (campo abierto y preferencia luz/oscuridad) para evaluar ansiedad y estrés. Luego se realizó un corte en la parte inferior de la aleta caudal para estudiar el efecto del estrés en la regeneración de los tejidos.Magíster en Ingeniería BiomédicaMaestría10 hojasapplication/pdfengUniversidad de los AndesMaestría en Ingeniería BiomédicaFacultad de IngenieríaDepartamento de Ingeniería BiomédicaEffects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)Trabajo de grado - Maestríainfo:eu-repo/semantics/masterThesishttp://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/TMPeces cebraAletas (Anatomía)Regeneración (Biología)Estrés postraumáticoAnsiedadIngeniería201213742Publicationhttps://scholar.google.es/citations?user=kNy3dl8AAAAJvirtual::12764-10000-0002-2050-5511virtual::12764-1https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001480053virtual::12764-13040266a-72bf-4378-a8cf-f64f7a2c5a49virtual::12764-13040266a-72bf-4378-a8cf-f64f7a2c5a49virtual::12764-1THUMBNAIL23420.pdf.jpg23420.pdf.jpgIM Thumbnailimage/jpeg29651https://repositorio.uniandes.edu.co/bitstreams/596243c9-9eee-41ff-9724-87ed80423b27/download9d4bbe1550e608500a8ea3f70df647caMD55TEXT23420.pdf.txt23420.pdf.txtExtracted texttext/plain35841https://repositorio.uniandes.edu.co/bitstreams/1702bdf9-727d-475d-a408-405f63faef01/download893cf54f639961422df41223cba94f52MD54ORIGINAL23420.pdfapplication/pdf12141595https://repositorio.uniandes.edu.co/bitstreams/353d7771-2958-4aee-a6fe-23b005f4cde1/download59ef4fcd76f007fd566baf0a9bcf4479MD511992/50943oai:repositorio.uniandes.edu.co:1992/509432024-03-13 14:46:12.072http://creativecommons.org/licenses/by-nc-nd/4.0/open.accesshttps://repositorio.uniandes.edu.coRepositorio institucional Sénecaadminrepositorio@uniandes.edu.co
dc.title.spa.fl_str_mv Effects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)
title Effects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)
spellingShingle Effects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)
Peces cebra
Aletas (Anatomía)
Regeneración (Biología)
Estrés postraumático
Ansiedad
Ingeniería
title_short Effects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)
title_full Effects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)
title_fullStr Effects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)
title_full_unstemmed Effects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)
title_sort Effects of chronic stress exposure on the anxiogenic behavior and regenerative capacity of zebrafish (Danio rerio)
dc.creator.fl_str_mv Henríquez Martínez, Angie
dc.contributor.advisor.none.fl_str_mv Bloch Morel, Natasha Ivonne
Akle Álvarez, Verónica
dc.contributor.author.none.fl_str_mv Henríquez Martínez, Angie
dc.subject.armarc.es_CO.fl_str_mv Peces cebra
Aletas (Anatomía)
Regeneración (Biología)
Estrés postraumático
Ansiedad
topic Peces cebra
Aletas (Anatomía)
Regeneración (Biología)
Estrés postraumático
Ansiedad
Ingeniería
dc.subject.themes.none.fl_str_mv Ingeniería
description Environmental stimuli such as daily routine, dietary habits and stress are strongly related to the physiology of our body. However, we still do not know entirely how this relationship occurs. The zebrafish has been used as a promising model in behavior, stress, anxiety and neuroscience research, thanks to its homology with vertebrates like rodents and mammals. Here in this study, we report preliminary results about the effect of chronic stress on the regeneration of the caudal fin in zebrafish (Danio rerio). We exposed fish to a UCS protocol to stimulated chronic stress conditions and performed behavioral tests (open field and light/dark preference) to evaluated anxiety-like behavior. Then we cut the lower part of the caudal fin to evaluated the effect of the stress on tissue regeneration.
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2021-08-10T18:04:35Z
dc.date.available.none.fl_str_mv 2021-08-10T18:04:35Z
dc.date.issued.none.fl_str_mv 2021
dc.type.spa.fl_str_mv Trabajo de grado - Maestría
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dc.identifier.pdf.none.fl_str_mv 23420.pdf
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dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Séneca
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url http://hdl.handle.net/1992/50943
identifier_str_mv 23420.pdf
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reponame:Repositorio Institucional Séneca
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dc.language.iso.none.fl_str_mv eng
language eng
dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
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rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
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eu_rights_str_mv openAccess
dc.format.extent.none.fl_str_mv 10 hojas
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad de los Andes
dc.publisher.program.none.fl_str_mv Maestría en Ingeniería Biomédica
dc.publisher.faculty.none.fl_str_mv Facultad de Ingeniería
dc.publisher.department.none.fl_str_mv Departamento de Ingeniería Biomédica
publisher.none.fl_str_mv Universidad de los Andes
institution Universidad de los Andes
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