4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes
En este documento se presentan los resultados del trabajo de investigación de Doctorado en Ciencias-Química titulado "4-formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes", desarrollado en el Grupo de Investigación de Com...
- Autores:
-
Aranzazu Giraldo, Sandra Lorena
- Tipo de recurso:
- Doctoral thesis
- Fecha de publicación:
- 2022
- Institución:
- Universidad de los Andes
- Repositorio:
- Séneca: repositorio Uniandes
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.uniandes.edu.co:1992/60021
- Acceso en línea:
- http://hdl.handle.net/1992/60021
- Palabra clave:
- Pirazoles
Pirazolo[1,5-a]pirimidinas
Antifúngicos
Química
- Rights
- openAccess
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes |
| title |
4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes |
| spellingShingle |
4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes Pirazoles Pirazolo[1,5-a]pirimidinas Antifúngicos Química |
| title_short |
4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes |
| title_full |
4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes |
| title_fullStr |
4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes |
| title_full_unstemmed |
4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes |
| title_sort |
4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes |
| dc.creator.fl_str_mv |
Aranzazu Giraldo, Sandra Lorena |
| dc.contributor.advisor.none.fl_str_mv |
Portilla Salinas, Jaime Antonio |
| dc.contributor.author.none.fl_str_mv |
Aranzazu Giraldo, Sandra Lorena |
| dc.contributor.jury.none.fl_str_mv |
Gamba Sánchez, Diego Alexander Altarejos Caballero, Joaquín Cuervo Prado, Paola Andrea |
| dc.contributor.researchgroup.es_CO.fl_str_mv |
Grupo de Investigación en Compuestos Biorgánicos (GICOBIORG) |
| dc.subject.keyword.none.fl_str_mv |
Pirazoles Pirazolo[1,5-a]pirimidinas Antifúngicos |
| topic |
Pirazoles Pirazolo[1,5-a]pirimidinas Antifúngicos Química |
| dc.subject.themes.es_CO.fl_str_mv |
Química |
| description |
En este documento se presentan los resultados del trabajo de investigación de Doctorado en Ciencias-Química titulado "4-formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes", desarrollado en el Grupo de Investigación de Compuestos Biorgánicos (GICOBIORG) de la Universidad de Los Andes, bajo la dirección del Dr. Jaime Antonio Portilla Salinas. Adicionalmente, se lograron hacer estudios de actividad antifúngica en el Grupo de Investigación Celular y Molecular de Microorganismos Patógenos de la Universidad de los Andes que dirige la Dra. Adriana Marcela Celis Ramírez. Los capítulos que conforman este manuscrito son siete. El primero, la conceptualización y los antecedentes generales y del grupo de investigación; el segundo, el planteamiento del problema que fue la principal motivación para llevar a cabo la investigación; el tercero, los objetivos; el cuarto, los resultados y discusión de la síntesis, actividad antifúngica y estudios fotofísicos; el quinto, conclusiones; el sexto; perspectivas; el séptimo la sección experimental; y por último la bibliografía. |
| publishDate |
2022 |
| dc.date.accessioned.none.fl_str_mv |
2022-08-23T13:58:15Z |
| dc.date.available.none.fl_str_mv |
2022-08-23T13:58:15Z |
| dc.date.issued.none.fl_str_mv |
2022-05-25 |
| dc.type.es_CO.fl_str_mv |
Trabajo de grado - Doctorado |
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info:eu-repo/semantics/doctoralThesis |
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info:eu-repo/semantics/acceptedVersion |
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http://purl.org/coar/resource_type/c_db06 |
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Text |
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https://purl.org/redcol/resource_type/TD |
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http://purl.org/coar/resource_type/c_db06 |
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http://hdl.handle.net/1992/60021 |
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10.57784/1992/60021 |
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instname:Universidad de los Andes |
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reponame:Repositorio Institucional Séneca |
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repourl:https://repositorio.uniandes.edu.co/ |
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http://hdl.handle.net/1992/60021 |
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10.57784/1992/60021 instname:Universidad de los Andes reponame:Repositorio Institucional Séneca repourl:https://repositorio.uniandes.edu.co/ |
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spa |
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spa |
| dc.relation.references.es_CO.fl_str_mv |
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Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Portilla Salinas, Jaime Antoniovirtual::20928-1Aranzazu Giraldo, Sandra Lorenaf3b4fecb-6420-4cad-b11a-05673397f322600Gamba Sánchez, Diego AlexanderAltarejos Caballero, JoaquínCuervo Prado, Paola AndreaGrupo de Investigación en Compuestos Biorgánicos (GICOBIORG)2022-08-23T13:58:15Z2022-08-23T13:58:15Z2022-05-25http://hdl.handle.net/1992/6002110.57784/1992/60021instname:Universidad de los Andesreponame:Repositorio Institucional Sénecarepourl:https://repositorio.uniandes.edu.co/En este documento se presentan los resultados del trabajo de investigación de Doctorado en Ciencias-Química titulado "4-formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentes", desarrollado en el Grupo de Investigación de Compuestos Biorgánicos (GICOBIORG) de la Universidad de Los Andes, bajo la dirección del Dr. Jaime Antonio Portilla Salinas. Adicionalmente, se lograron hacer estudios de actividad antifúngica en el Grupo de Investigación Celular y Molecular de Microorganismos Patógenos de la Universidad de los Andes que dirige la Dra. Adriana Marcela Celis Ramírez. Los capítulos que conforman este manuscrito son siete. El primero, la conceptualización y los antecedentes generales y del grupo de investigación; el segundo, el planteamiento del problema que fue la principal motivación para llevar a cabo la investigación; el tercero, los objetivos; el cuarto, los resultados y discusión de la síntesis, actividad antifúngica y estudios fotofísicos; el quinto, conclusiones; el sexto; perspectivas; el séptimo la sección experimental; y por último la bibliografía.El Ministerio de Ciencias Tecnología e Innovación (Minciencias) mediante la convocatoria 727 de 2015Doctor en Ciencias - QuímicaDoctoradoSíntesis orgánica, Fotofísica y actividad antifúngica136 páginasapplication/pdfspaUniversidad de los AndesDoctorado en Ciencias - QuímicaFacultad de CienciasDepartamento de Química4-Formilpirazoles y 3-formilpirazolo[1,5-a]pirimidinas como precursores de potenciales agentes antifúngicos fluorescentesTrabajo de grado - Doctoradoinfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_db06Texthttps://purl.org/redcol/resource_type/TDPirazolesPirazolo[1,5-a]pirimidinasAntifúngicosQuímicaEicher, T.; Hauptmann, S.; Speicher, A. Pyrazole. In The Chemistry of Heterocycles: Structure, Reactions, Synthesis, and Applications; 2nd ed.; Wiley-VCH Verlag GmbH & Co. KGaA, 2003; pp 179-184.Joule, J. A. ; Mills, K. 1,2 - Azoles: Pyrazoles, Isothiazoles, Isoxazoles: Reactions and Synthesis. In Heterocyclic Chemistry; 5th ed.; John Wiley & Sons Ltd, 2010; pp 485-501.Castillo, J. C.; Portilla, J. Recent Advances in the Synthesis of New Pyrazole Derivatives. Targets Heterocycl. Syst. 2018, 22 (18), 194-223. https://doi.org/10.17374/targets.2019.22.194.Ortiz, M.-C.; Portilla, J. Access to Five-Membered N-Heteroaromatic Compounds: Current Appoach Based on Microwave-Assisted Synthesis. Targets Heterocycl. Syst. 2021, 25, 436-462. https://doi.org/10.17374/targets.2022.25.436.Devi, N.; Shankar, R.; Singh, V. 4-Formyl-Pyrazole-3-Carboxylate: A Useful Aldo-X Bifunctional Precursor for the Syntheses of Pyrazole-Fused/Substituted Frameworks. J. Heterocycl. 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