Impulsivity traits in patients with multiple sclerosis

Background Multiple sclerosis (MS) is a demyelinating disease with a lifetime prevalence of 4.41/100000 in Bogota, Colombia. It is known that it can be related with neuropsychiatric disorders, increasing by a factor of three the prevalence of depression in MS patients compared to general population....

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Autores:
Toro, Jaime
Blanco, Luisa
Orozco-Cabal, Luis Felipe
Duque, Alejandra
Patiño, Jorge
Díaz, Camilo
Reyes, Saúl
Burbano, Lisseth
Cuéllar-Giraldo, David Felipe
Cortés, Fabián
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/3627
Acceso en línea:
http://hdl.handle.net/20.500.12495/3627
https://doi.org/10.1016/j.msard.2018.04.011
https://repositorio.unbosque.edu.co
Palabra clave:
Multiple sclerosis
Impulsivity
Depression
Neuropsychiatric disorders
Rights
openAccess
License
Acceso abierto
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dc.title.spa.fl_str_mv Impulsivity traits in patients with multiple sclerosis
dc.title.translated.spa.fl_str_mv Impulsivity traits in patients with multiple sclerosis
title Impulsivity traits in patients with multiple sclerosis
spellingShingle Impulsivity traits in patients with multiple sclerosis
Multiple sclerosis
Impulsivity
Depression
Neuropsychiatric disorders
title_short Impulsivity traits in patients with multiple sclerosis
title_full Impulsivity traits in patients with multiple sclerosis
title_fullStr Impulsivity traits in patients with multiple sclerosis
title_full_unstemmed Impulsivity traits in patients with multiple sclerosis
title_sort Impulsivity traits in patients with multiple sclerosis
dc.creator.fl_str_mv Toro, Jaime
Blanco, Luisa
Orozco-Cabal, Luis Felipe
Duque, Alejandra
Patiño, Jorge
Díaz, Camilo
Reyes, Saúl
Burbano, Lisseth
Cuéllar-Giraldo, David Felipe
Cortés, Fabián
dc.contributor.author.none.fl_str_mv Toro, Jaime
Blanco, Luisa
Orozco-Cabal, Luis Felipe
Duque, Alejandra
Patiño, Jorge
Díaz, Camilo
Reyes, Saúl
Burbano, Lisseth
Cuéllar-Giraldo, David Felipe
Cortés, Fabián
dc.contributor.orcid.none.fl_str_mv Toro, Jaime [0000-0001-7129-0058]
dc.subject.keywords.spa.fl_str_mv Multiple sclerosis
Impulsivity
Depression
Neuropsychiatric disorders
topic Multiple sclerosis
Impulsivity
Depression
Neuropsychiatric disorders
description Background Multiple sclerosis (MS) is a demyelinating disease with a lifetime prevalence of 4.41/100000 in Bogota, Colombia. It is known that it can be related with neuropsychiatric disorders, increasing by a factor of three the prevalence of depression in MS patients compared to general population. However, less attention has been given to the association between MS and impulsive behavior. Methods This cross-sectional study compared the levels of impulsivity controlling for the presence of MS. 60 patients with MS and 60 sex- and age-matched subjects without MS were included. In order to assess depression and impulsivity, participants completed the 13-item short form of the Beck Depression Inventory (BDI-SF), the self-report Barratt Impulsiveness Scale version 11 (BIS-11) and the Immediate and Delayed Memory Tasks (IMT-DMT) as an objective measure of impulsive behavior. Results Total scores, motor and cognitive subscales on the BIS-11 were significantly higher in the MS group. However, median BDI-SF score was also higher in MS patients than in subjects without MS (p < 0.001). To rule out depression as a confounding factor, stratification was performed using the BDI-SF score. In the subgroup of individuals with a BDI-SF< 8, the BIS-11 cognitive subscale scores were significantly higher in patients with MS than in subjects without MS ( p = 0.041). In the IMT/DMT test, subjects with MS had a fewer number of correct detections than did subjects without MS, after controlling for BDI-SF score ( p = 0.0001/ p = 0.003). The ratio of commission errors to correct detections in the IMT was significantly higher in the MS group ( p = 0.011). Conclusion Patients with MS showed higher levels of cognitive impulsivity than subjects without MS. Objective measures for impulsiveness further support this finding. Impulsiveness scales scores might be biased by depression, which should be considered when assessing impulsivity in MS. Abbreviations: BDI-SF ( Beck Depression Inventory – Short Form), BIS-11 ( Barratt Impulsiveness Scale version 11), IMT/DMT ( Immediate and Delayed Memory Tasks), CE ( Commission errors), CD ( Correct detections), RE ( Random errors)
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-07-31T13:07:51Z
dc.date.available.none.fl_str_mv 2020-07-31T13:07:51Z
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dc.identifier.issn.none.fl_str_mv 2211-0356
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dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.msard.2018.04.011
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
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url http://hdl.handle.net/20.500.12495/3627
https://doi.org/10.1016/j.msard.2018.04.011
https://repositorio.unbosque.edu.co
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv Multiple Sclerosis and Related Disorders, 2211-0356, Vol. 22, 2018, p. 148-152
dc.relation.uri.none.fl_str_mv https://www.sciencedirect.com/science/article/abs/pii/S2211034818301299
dc.rights.local.spa.fl_str_mv Acceso abierto
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2018-05-01
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dc.publisher.spa.fl_str_mv Elsevier
dc.publisher.journal.spa.fl_str_mv Multiple Sclerosis and Related Disorders
institution Universidad El Bosque
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spelling Toro, JaimeBlanco, LuisaOrozco-Cabal, Luis FelipeDuque, AlejandraPatiño, JorgeDíaz, CamiloReyes, SaúlBurbano, LissethCuéllar-Giraldo, David FelipeCortés, FabiánToro, Jaime [0000-0001-7129-0058]2020-07-31T13:07:51Z2020-07-31T13:07:51Z2211-0356http://hdl.handle.net/20.500.12495/3627https://doi.org/10.1016/j.msard.2018.04.011instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquehttps://repositorio.unbosque.edu.coapplication/pdfengElsevierMultiple Sclerosis and Related DisordersMultiple Sclerosis and Related Disorders, 2211-0356, Vol. 22, 2018, p. 148-152https://www.sciencedirect.com/science/article/abs/pii/S2211034818301299Impulsivity traits in patients with multiple sclerosisImpulsivity traits in patients with multiple sclerosisArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85Multiple sclerosisImpulsivityDepressionNeuropsychiatric disordersBackground Multiple sclerosis (MS) is a demyelinating disease with a lifetime prevalence of 4.41/100000 in Bogota, Colombia. It is known that it can be related with neuropsychiatric disorders, increasing by a factor of three the prevalence of depression in MS patients compared to general population. However, less attention has been given to the association between MS and impulsive behavior. Methods This cross-sectional study compared the levels of impulsivity controlling for the presence of MS. 60 patients with MS and 60 sex- and age-matched subjects without MS were included. In order to assess depression and impulsivity, participants completed the 13-item short form of the Beck Depression Inventory (BDI-SF), the self-report Barratt Impulsiveness Scale version 11 (BIS-11) and the Immediate and Delayed Memory Tasks (IMT-DMT) as an objective measure of impulsive behavior. Results Total scores, motor and cognitive subscales on the BIS-11 were significantly higher in the MS group. However, median BDI-SF score was also higher in MS patients than in subjects without MS (p < 0.001). To rule out depression as a confounding factor, stratification was performed using the BDI-SF score. In the subgroup of individuals with a BDI-SF< 8, the BIS-11 cognitive subscale scores were significantly higher in patients with MS than in subjects without MS ( p = 0.041). In the IMT/DMT test, subjects with MS had a fewer number of correct detections than did subjects without MS, after controlling for BDI-SF score ( p = 0.0001/ p = 0.003). The ratio of commission errors to correct detections in the IMT was significantly higher in the MS group ( p = 0.011). Conclusion Patients with MS showed higher levels of cognitive impulsivity than subjects without MS. Objective measures for impulsiveness further support this finding. Impulsiveness scales scores might be biased by depression, which should be considered when assessing impulsivity in MS. Abbreviations: BDI-SF ( Beck Depression Inventory – Short Form), BIS-11 ( Barratt Impulsiveness Scale version 11), IMT/DMT ( Immediate and Delayed Memory Tasks), CE ( Commission errors), CD ( Correct detections), RE ( Random errors)Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abierto2018-05-01ORIGINALToro, Jaime.pdfToro, Jaime.pdfapplication/pdf226092https://repositorio.unbosque.edu.co/bitstreams/b604eb20-73c8-4d8f-8141-e20d460d2095/download2d3be88db644fa5c2f2152b068de22f3MD53LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/6d39eb84-e455-4acc-95b1-f496e5531e01/download8a4605be74aa9ea9d79846c1fba20a33MD52THUMBNAILToro, Jaime.pdf.jpgToro, Jaime.pdf.jpgIM Thumbnailimage/jpeg12216https://repositorio.unbosque.edu.co/bitstreams/01a4ec5c-bfd4-4f7d-b036-7787b637cd0d/downloadbf85caeb050788e38fce804a8b20f0baMD54TEXTToro, Jaime.pdf.txtToro, Jaime.pdf.txtExtracted texttext/plain34756https://repositorio.unbosque.edu.co/bitstreams/b0145fc5-d2f9-4cc6-b4fa-9ead3da18f10/download48cec572582ee516a1c23ca5a14c18ceMD5520.500.12495/3627oai:repositorio.unbosque.edu.co:20.500.12495/36272024-02-07 04:52:08.107restrictedhttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.comTk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=