Is there a relationship between spondyloarthritis and periodontitis? a case-control study
Objective To compare the frequency and severity of periodontitis in patients with spondyloarthritis (SpA) with healthy control individuals, through the evaluatio of clinical, serological and microbiological periodontal condition. Methods Patients with a diagnosis of SpA (n=78) and biological disease...
- Autores:
-
Bautista Molano, Wilson
van der Heijde, Desirée
Landewé, Robert
Lafaurie, Gloria I.
de Ávila, Juliette
Valle Oñate, Rafael
Romero Sanchez, Consuelo
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2017
- Institución:
- Universidad El Bosque
- Repositorio:
- Repositorio U. El Bosque
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.unbosque.edu.co:20.500.12495/5882
- Acceso en línea:
- http://hdl.handle.net/20.500.12495/5882
https://dx.doi.org/10.1136%2Frmdopen-2017-000547
- Palabra clave:
- Espondiloartritis
Periodontitis
Microbiología
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
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|
dc.title.spa.fl_str_mv |
Is there a relationship between spondyloarthritis and periodontitis? a case-control study |
dc.title.translated.spa.fl_str_mv |
Is there a relationship between spondyloarthritis and periodontitis? a case-control study |
title |
Is there a relationship between spondyloarthritis and periodontitis? a case-control study |
spellingShingle |
Is there a relationship between spondyloarthritis and periodontitis? a case-control study Espondiloartritis Periodontitis Microbiología |
title_short |
Is there a relationship between spondyloarthritis and periodontitis? a case-control study |
title_full |
Is there a relationship between spondyloarthritis and periodontitis? a case-control study |
title_fullStr |
Is there a relationship between spondyloarthritis and periodontitis? a case-control study |
title_full_unstemmed |
Is there a relationship between spondyloarthritis and periodontitis? a case-control study |
title_sort |
Is there a relationship between spondyloarthritis and periodontitis? a case-control study |
dc.creator.fl_str_mv |
Bautista Molano, Wilson van der Heijde, Desirée Landewé, Robert Lafaurie, Gloria I. de Ávila, Juliette Valle Oñate, Rafael Romero Sanchez, Consuelo |
dc.contributor.author.none.fl_str_mv |
Bautista Molano, Wilson van der Heijde, Desirée Landewé, Robert Lafaurie, Gloria I. de Ávila, Juliette Valle Oñate, Rafael Romero Sanchez, Consuelo |
dc.contributor.orcid.none.fl_str_mv |
Bautista Molano, Wilson [0000-0003-0684-9542] |
dc.subject.decs.spa.fl_str_mv |
Espondiloartritis Periodontitis Microbiología |
topic |
Espondiloartritis Periodontitis Microbiología |
description |
Objective To compare the frequency and severity of periodontitis in patients with spondyloarthritis (SpA) with healthy control individuals, through the evaluatio of clinical, serological and microbiological periodontal condition. Methods Patients with a diagnosis of SpA (n=78) and biological disease-modifying antirheumatic drug (bDMARD) naive fulfilling the Assessment of SpondyloArthritis international Society (ASAS) classification criteria as well as 156 healthy controls matched for age/gender were included. Two trained and calibrated periodontologists performed the periodontal clinical assessment. The presence of periodontitis and its severity were determined according to the criteria established by the Centers for Disease Control and Prevention-American Academy of Periodontology. The clinical periodontal variables, IgG1/IgG2 antibodies against Porphyromonas gingivalis andperiodontopathic bacterial identification, were also established. Comparisons of periodontal characteristics between the patients with SpA and the control group were performed using univariable analyses. A logistic regression analyses was performed to calculate the OR (95% CI) for diagnosis of periodontitis in patients with SpA and matched controls. Results A diagnosis of periodontitis was established in 56% in patients with SpA versus 69% of healthy controls (P≤ 0.01). Severe periodontitis was found in 3% versus 12% in SpA versus healthy controls, respectively (P≤ 0.01). There was no significant increase of frequency of any periodontal variable, IgG1/IgG2 antibodies against P. gingivalis or the presence of periodontopathic bacteria between patients with SpA and control group. Periodontitis was not positively associated with a diagnosis of SpA (OR: 0.57, 95% CI 0.32 to 1.00, P=0.05) in the logistic regression analyses. Conclusions We found a lower rather than a higher frequency and severity of periodontitis in patients with SpA in comparison with healthy control individuals. Our findings suggest that there is no positive association between SpA and periodontitis in Colombian patients. |
publishDate |
2017 |
dc.date.issued.none.fl_str_mv |
2017-11 |
dc.date.accessioned.none.fl_str_mv |
2021-05-19T16:46:44Z |
dc.date.available.none.fl_str_mv |
2021-05-19T16:46:44Z |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.local.none.fl_str_mv |
Artículo de revista |
dc.type.coar.none.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/article |
format |
http://purl.org/coar/resource_type/c_6501 |
dc.identifier.issn.none.fl_str_mv |
2056-5933 |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12495/5882 |
dc.identifier.doi.none.fl_str_mv |
https://dx.doi.org/10.1136%2Frmdopen-2017-000547 |
dc.identifier.instname.spa.fl_str_mv |
instname:Universidad El Bosque |
dc.identifier.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional Universidad El Bosque |
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repourl:https://repositorio.unbosque.edu.co |
identifier_str_mv |
2056-5933 instname:Universidad El Bosque reponame:Repositorio Institucional Universidad El Bosque repourl:https://repositorio.unbosque.edu.co |
url |
http://hdl.handle.net/20.500.12495/5882 https://dx.doi.org/10.1136%2Frmdopen-2017-000547 |
dc.language.iso.none.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofseries.spa.fl_str_mv |
RMD open, 2056-5933, Vol. 3,Nro. 2, 2017, |
dc.relation.uri.none.fl_str_mv |
https://rmdopen.bmj.com/content/3/2/e000547 |
dc.rights.*.fl_str_mv |
Atribución-NoComercial 4.0 Internacional |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc/4.0/ |
dc.rights.local.spa.fl_str_mv |
Acceso abierto |
dc.rights.accessrights.none.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess Acceso abierto |
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Atribución-NoComercial 4.0 Internacional http://creativecommons.org/licenses/by-nc/4.0/ Acceso abierto http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.spa.fl_str_mv |
BMJ Publishing Group Ltd European League Against Rheumatism |
dc.publisher.journal.spa.fl_str_mv |
RMD Open |
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Universidad El Bosque |
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Bautista Molano, Wilsonvan der Heijde, DesiréeLandewé, RobertLafaurie, Gloria I.de Ávila, JulietteValle Oñate, RafaelRomero Sanchez, ConsueloBautista Molano, Wilson [0000-0003-0684-9542]2021-05-19T16:46:44Z2021-05-19T16:46:44Z2017-112056-5933http://hdl.handle.net/20.500.12495/5882https://dx.doi.org/10.1136%2Frmdopen-2017-000547instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coapplication/pdfengBMJ Publishing Group LtdEuropean League Against RheumatismRMD OpenRMD open, 2056-5933, Vol. 3,Nro. 2, 2017,https://rmdopen.bmj.com/content/3/2/e000547Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abiertoIs there a relationship between spondyloarthritis and periodontitis? a case-control studyIs there a relationship between spondyloarthritis and periodontitis? a case-control studyArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85EspondiloartritisPeriodontitisMicrobiologíaObjective To compare the frequency and severity of periodontitis in patients with spondyloarthritis (SpA) with healthy control individuals, through the evaluatio of clinical, serological and microbiological periodontal condition. Methods Patients with a diagnosis of SpA (n=78) and biological disease-modifying antirheumatic drug (bDMARD) naive fulfilling the Assessment of SpondyloArthritis international Society (ASAS) classification criteria as well as 156 healthy controls matched for age/gender were included. Two trained and calibrated periodontologists performed the periodontal clinical assessment. The presence of periodontitis and its severity were determined according to the criteria established by the Centers for Disease Control and Prevention-American Academy of Periodontology. The clinical periodontal variables, IgG1/IgG2 antibodies against Porphyromonas gingivalis andperiodontopathic bacterial identification, were also established. Comparisons of periodontal characteristics between the patients with SpA and the control group were performed using univariable analyses. A logistic regression analyses was performed to calculate the OR (95% CI) for diagnosis of periodontitis in patients with SpA and matched controls. Results A diagnosis of periodontitis was established in 56% in patients with SpA versus 69% of healthy controls (P≤ 0.01). Severe periodontitis was found in 3% versus 12% in SpA versus healthy controls, respectively (P≤ 0.01). There was no significant increase of frequency of any periodontal variable, IgG1/IgG2 antibodies against P. gingivalis or the presence of periodontopathic bacteria between patients with SpA and control group. Periodontitis was not positively associated with a diagnosis of SpA (OR: 0.57, 95% CI 0.32 to 1.00, P=0.05) in the logistic regression analyses. Conclusions We found a lower rather than a higher frequency and severity of periodontitis in patients with SpA in comparison with healthy control individuals. Our findings suggest that there is no positive association between SpA and periodontitis in Colombian patients.ORIGINALBautista_Molano_Wilson_2017.pdfBautista_Molano_Wilson_2017.pdfapplication/pdf324420https://repositorio.unbosque.edu.co/bitstreams/0b2cd62b-0b27-4764-93f5-c95ca025a507/download4c5b156e0bec4db3dbf8a1af643d6b48MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8914https://repositorio.unbosque.edu.co/bitstreams/a5dfd7a6-28dd-4dd1-8f6c-63c700182088/download24013099e9e6abb1575dc6ce0855efd5MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/787da98a-5388-4f34-af3f-3d5a660fa4cc/download8a4605be74aa9ea9d79846c1fba20a33MD53THUMBNAILBautista_Molano_Wilson_2017.pdf.jpgBautista_Molano_Wilson_2017.pdf.jpgIM Thumbnailimage/jpeg11924https://repositorio.unbosque.edu.co/bitstreams/caab3b6e-53e2-484a-bba5-0d33aa3548d8/downloadd2df9d9f9d30e694ff2178568d2da86fMD54TEXTBautista_Molano_Wilson_2017.pdf.txtBautista_Molano_Wilson_2017.pdf.txtExtracted texttext/plain33740https://repositorio.unbosque.edu.co/bitstreams/3e48dd04-8be3-41a9-91e2-a14906d51b80/downloada8256bc2af0ba5c3db5d6ef0d81b8eddMD5520.500.12495/5882oai:repositorio.unbosque.edu.co:20.500.12495/58822024-02-07 00:21:21.991http://creativecommons.org/licenses/by-nc/4.0/Atribución-NoComercial 4.0 Internacionalopen.accesshttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.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 |