Is there a relationship between spondyloarthritis and periodontitis? a case-control study

Objective To compare the frequency and severity of periodontitis in patients with spondyloarthritis (SpA) with healthy control individuals, through the evaluatio of clinical, serological and microbiological periodontal condition. Methods Patients with a diagnosis of SpA (n=78) and biological disease...

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Autores:
Bautista Molano, Wilson
van der Heijde, Desirée
Landewé, Robert
Lafaurie, Gloria I.
de Ávila, Juliette
Valle Oñate, Rafael
Romero Sanchez, Consuelo
Tipo de recurso:
Article of journal
Fecha de publicación:
2017
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/5882
Acceso en línea:
http://hdl.handle.net/20.500.12495/5882
https://dx.doi.org/10.1136%2Frmdopen-2017-000547
Palabra clave:
Espondiloartritis
Periodontitis
Microbiología
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
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dc.title.spa.fl_str_mv Is there a relationship between spondyloarthritis and periodontitis? a case-control study
dc.title.translated.spa.fl_str_mv Is there a relationship between spondyloarthritis and periodontitis? a case-control study
title Is there a relationship between spondyloarthritis and periodontitis? a case-control study
spellingShingle Is there a relationship between spondyloarthritis and periodontitis? a case-control study
Espondiloartritis
Periodontitis
Microbiología
title_short Is there a relationship between spondyloarthritis and periodontitis? a case-control study
title_full Is there a relationship between spondyloarthritis and periodontitis? a case-control study
title_fullStr Is there a relationship between spondyloarthritis and periodontitis? a case-control study
title_full_unstemmed Is there a relationship between spondyloarthritis and periodontitis? a case-control study
title_sort Is there a relationship between spondyloarthritis and periodontitis? a case-control study
dc.creator.fl_str_mv Bautista Molano, Wilson
van der Heijde, Desirée
Landewé, Robert
Lafaurie, Gloria I.
de Ávila, Juliette
Valle Oñate, Rafael
Romero Sanchez, Consuelo
dc.contributor.author.none.fl_str_mv Bautista Molano, Wilson
van der Heijde, Desirée
Landewé, Robert
Lafaurie, Gloria I.
de Ávila, Juliette
Valle Oñate, Rafael
Romero Sanchez, Consuelo
dc.contributor.orcid.none.fl_str_mv Bautista Molano, Wilson [0000-0003-0684-9542]
dc.subject.decs.spa.fl_str_mv Espondiloartritis
Periodontitis
Microbiología
topic Espondiloartritis
Periodontitis
Microbiología
description Objective To compare the frequency and severity of periodontitis in patients with spondyloarthritis (SpA) with healthy control individuals, through the evaluatio of clinical, serological and microbiological periodontal condition. Methods Patients with a diagnosis of SpA (n=78) and biological disease-modifying antirheumatic drug (bDMARD) naive fulfilling the Assessment of SpondyloArthritis international Society (ASAS) classification criteria as well as 156 healthy controls matched for age/gender were included. Two trained and calibrated periodontologists performed the periodontal clinical assessment. The presence of periodontitis and its severity were determined according to the criteria established by the Centers for Disease Control and Prevention-American Academy of Periodontology. The clinical periodontal variables, IgG1/IgG2 antibodies against Porphyromonas gingivalis andperiodontopathic bacterial identification, were also established. Comparisons of periodontal characteristics between the patients with SpA and the control group were performed using univariable analyses. A logistic regression analyses was performed to calculate the OR (95% CI) for diagnosis of periodontitis in patients with SpA and matched controls. Results A diagnosis of periodontitis was established in 56% in patients with SpA versus 69% of healthy controls (P≤ 0.01). Severe periodontitis was found in 3% versus 12% in SpA versus healthy controls, respectively (P≤ 0.01). There was no significant increase of frequency of any periodontal variable, IgG1/IgG2 antibodies against P. gingivalis or the presence of periodontopathic bacteria between patients with SpA and control group. Periodontitis was not positively associated with a diagnosis of SpA (OR: 0.57, 95% CI 0.32 to 1.00, P=0.05) in the logistic regression analyses. Conclusions We found a lower rather than a higher frequency and severity of periodontitis in patients with SpA in comparison with healthy control individuals. Our findings suggest that there is no positive association between SpA and periodontitis in Colombian patients.
publishDate 2017
dc.date.issued.none.fl_str_mv 2017-11
dc.date.accessioned.none.fl_str_mv 2021-05-19T16:46:44Z
dc.date.available.none.fl_str_mv 2021-05-19T16:46:44Z
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dc.type.local.none.fl_str_mv Artículo de revista
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dc.identifier.doi.none.fl_str_mv https://dx.doi.org/10.1136%2Frmdopen-2017-000547
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
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https://dx.doi.org/10.1136%2Frmdopen-2017-000547
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv
RMD open, 2056-5933, Vol. 3,Nro. 2, 2017,
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dc.rights.*.fl_str_mv Atribución-NoComercial 4.0 Internacional
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eu_rights_str_mv openAccess
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dc.publisher.spa.fl_str_mv BMJ Publishing Group Ltd
European League Against Rheumatism
dc.publisher.journal.spa.fl_str_mv RMD Open
institution Universidad El Bosque
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spelling Bautista Molano, Wilsonvan der Heijde, DesiréeLandewé, RobertLafaurie, Gloria I.de Ávila, JulietteValle Oñate, RafaelRomero Sanchez, ConsueloBautista Molano, Wilson [0000-0003-0684-9542]2021-05-19T16:46:44Z2021-05-19T16:46:44Z2017-112056-5933http://hdl.handle.net/20.500.12495/5882https://dx.doi.org/10.1136%2Frmdopen-2017-000547instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coapplication/pdfengBMJ Publishing Group LtdEuropean League Against RheumatismRMD OpenRMD open, 2056-5933, Vol. 3,Nro. 2, 2017,https://rmdopen.bmj.com/content/3/2/e000547Atribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abiertoIs there a relationship between spondyloarthritis and periodontitis? a case-control studyIs there a relationship between spondyloarthritis and periodontitis? a case-control studyArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85EspondiloartritisPeriodontitisMicrobiologíaObjective To compare the frequency and severity of periodontitis in patients with spondyloarthritis (SpA) with healthy control individuals, through the evaluatio of clinical, serological and microbiological periodontal condition. Methods Patients with a diagnosis of SpA (n=78) and biological disease-modifying antirheumatic drug (bDMARD) naive fulfilling the Assessment of SpondyloArthritis international Society (ASAS) classification criteria as well as 156 healthy controls matched for age/gender were included. Two trained and calibrated periodontologists performed the periodontal clinical assessment. The presence of periodontitis and its severity were determined according to the criteria established by the Centers for Disease Control and Prevention-American Academy of Periodontology. The clinical periodontal variables, IgG1/IgG2 antibodies against Porphyromonas gingivalis andperiodontopathic bacterial identification, were also established. Comparisons of periodontal characteristics between the patients with SpA and the control group were performed using univariable analyses. A logistic regression analyses was performed to calculate the OR (95% CI) for diagnosis of periodontitis in patients with SpA and matched controls. Results A diagnosis of periodontitis was established in 56% in patients with SpA versus 69% of healthy controls (P≤ 0.01). Severe periodontitis was found in 3% versus 12% in SpA versus healthy controls, respectively (P≤ 0.01). There was no significant increase of frequency of any periodontal variable, IgG1/IgG2 antibodies against P. gingivalis or the presence of periodontopathic bacteria between patients with SpA and control group. Periodontitis was not positively associated with a diagnosis of SpA (OR: 0.57, 95% CI 0.32 to 1.00, P=0.05) in the logistic regression analyses. Conclusions We found a lower rather than a higher frequency and severity of periodontitis in patients with SpA in comparison with healthy control individuals. 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