Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana

Objetivos: Describir y correlacionar los hallazgos clínicos y patológicos de pacientes con LEL de colón manejados con mucosectomía endoscópica en el Centro de coloproctología y Endoscopia (CCE) entre los años 2015 a 2022, en Bogotá DC, Colombia. Materiales y métodos: Estudio observacional de pacient...

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Autores:: Pedraza Ciro, Mauricio
Carrera Siachoque, Javier Alejandro
Garcia Duperly, Rafael
Cabrera Vargas, Luis Felipe
Pérez Rivera, Carlos Jose

Tipo de recurso:: https://purl.org/coar/resource_type/c_7a1f

Fecha de publicación:: 2024

Institución:: Universidad El Bosque

Repositorio:: Repositorio U. El Bosque

Idioma:: spa

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repository_id_str
dc.title.none.fl_str_mv	Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana
dc.title.translated.none.fl_str_mv	Correlation between endoscopic findings and pathologies of lateral extension lesions of the colon, in a colombian population
title	Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana
spellingShingle	Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana Pólipos del Colon Colonoscopía Neoplasias Colorrectales Resección Endoscópica de la Mucosa Colon Polyps Colonoscopy Colorectal Neoplasms Endoscopic Mucosal Resection WO 100
title_short	Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana
title_full	Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana
title_fullStr	Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana
title_full_unstemmed	Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana
title_sort	Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana
dc.creator.fl_str_mv	Pedraza Ciro, Mauricio Carrera Siachoque, Javier Alejandro Garcia Duperly, Rafael Cabrera Vargas, Luis Felipe Pérez Rivera, Carlos Jose
dc.contributor.advisor.none.fl_str_mv	Carrera Siachoque, Javier Alejandro Peña, Fernando Yaacov
dc.contributor.author.none.fl_str_mv	Pedraza Ciro, Mauricio Carrera Siachoque, Javier Alejandro Garcia Duperly, Rafael Cabrera Vargas, Luis Felipe Pérez Rivera, Carlos Jose
dc.contributor.orcid.none.fl_str_mv	Pedraza Ciro, Mauricio [0000-0001-8726-5578]
dc.subject.none.fl_str_mv	Pólipos del Colon Colonoscopía Neoplasias Colorrectales Resección Endoscópica de la Mucosa
topic	Pólipos del Colon Colonoscopía Neoplasias Colorrectales Resección Endoscópica de la Mucosa Colon Polyps Colonoscopy Colorectal Neoplasms Endoscopic Mucosal Resection WO 100
dc.subject.keywords.none.fl_str_mv	Colon Polyps Colonoscopy Colorectal Neoplasms Endoscopic Mucosal Resection
dc.subject.nlm.none.fl_str_mv	WO 100
description	Objetivos: Describir y correlacionar los hallazgos clínicos y patológicos de pacientes con LEL de colón manejados con mucosectomía endoscópica en el Centro de coloproctología y Endoscopia (CCE) entre los años 2015 a 2022, en Bogotá DC, Colombia. Materiales y métodos: Estudio observacional de pacientes con lesiones de extensión lateral de colon que fueron llevados a manejo endoscópico con mucosectomía endoscópica. Se recopilaron datos clínicos, endoscópicos y patológicos de los pacientes, así como detalles sobre las técnicas endoscópicas utilizadas en su evaluación y tratamiento. Se realizó un análisis con pruebas de normalidad (Shapiro Wilk o Kolmogorov Smirnov) Resultados: De 8400 colonoscopias realizadas se identificaron 170 LEL de colon, 91 (55%) correspondieron al género masculino. La edad presento media 64 años RIQ(55 -70) años. La localización más frecuente fue el colon proximal 118(69,4 %) . Dentro de las características histológicas fue más prevalente la displasia bajo grado 128 (75,3%). El grupo de tamaño que mas se presento fue el de 20 a 29 mm en el 90(53 %), de 30 a 39 mm el 45(26,4) % y de 40 a 49 mm en el 20(11,8) %. La característica morfológica más prevalente fueron las lesiones granulares 141(83%) Conclusiones: Las LEL se presentan en un 2.9% de la poblacion estudiada, con mayor frecuencia en el colon proximal. Sus caracteres morfologicas estan dadas por tamaño de lesion de 20 a 40 mm de diámetro. El grado de displasia con mas frecuencia fue el bajo grado.
publishDate	2024
dc.date.accessioned.none.fl_str_mv	2024-07-25T19:51:54Z
dc.date.available.none.fl_str_mv	2024-07-25T19:51:54Z
dc.date.issued.none.fl_str_mv	2024-06
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dc.type.local.spa.fl_str_mv	Tesis/Trabajo de grado - Monografía - Especialización
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dc.type.driver.none.fl_str_mv	info:eu-repo/semantics/bachelorThesis
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dc.identifier.uri.none.fl_str_mv	https://hdl.handle.net/20.500.12495/12735
dc.identifier.instname.spa.fl_str_mv	instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv	reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv	repourl:https://repositorio.unbosque.edu.co
url	https://hdl.handle.net/20.500.12495/12735
identifier_str_mv	instname:Universidad El Bosque reponame:Repositorio Institucional Universidad El Bosque repourl:https://repositorio.unbosque.edu.co
dc.language.iso.fl_str_mv	spa
language	spa
dc.relation.references.none.fl_str_mv	1. Morgan E, Arnold M, Gini A, Lorenzoni V, Cabasag CJ, Laversanne M, Vignat J, Ferlay J, Murphy N, Bray F. Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN. Gut. 2023 Feb;72(2):338-344. doi: 10.1136/gutjnl-2022-327736. Epub 2022 Sep 8. PMID: 36604116. 2. The Global Cancer Observatory - All Rights Reserved, December, 2020. https://gco.iarc.fr/today/data/factsheets/cancers/10_8_9-Colorectum-fact-sheet.pdf 3. Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023 Jan;73(1):17-48. doi: 10.3322/caac.21763. PMID: 36633525. 4. Pardo C, Cendales R. Cancer incidence estimates and mortality for the top five cancer in Colombia, 2007-2011. Colomb Med (Cali). 2018 Mar 30;49(1):16-22. doi: 10.25100/cm.v49i1.3596. PMID: 29983460; PMCID: PMC6018817 5. Landin MD, Guerrón AD. Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection. Surg Clin North Am. 2020 Dec;100(6). 6. The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach and colon. Gastrointest Endosc. 2003;58(Suppl 6):S3-S43. 7. Pidala MJ, Cusick MV. The Difficult Colorectal Polyp. Surg Clin North Am. 2017 Jun;97(3):515-527. 8. Muto T, Kamiya J, Atkin S. Small ”flat adenomas” of the large bowel with special references to its clinic-pathologic features. Dis Colon Rectum. 1985 Dec;28(12):847-851. 9. Myung DS, Kweon SS, Lee J, Shin IS, Kim SW, Seo GS, Kim HS, Joo YE. Clinicopathological features of laterally spreading colorectal tumors and their association with advanced histology and invasiveness: An experience from Honam province of South Korea: A Honam Association for the Study of Intestinal Diseases (HASID). PLoS One. 2017 Oct 4;12(10):e0184205. doi: 10.1371/journal.pone.0184205. PMID: 28977010; PMCID: PMC5627894. 10. Watabe H, Yamaji Y, Okamoto M, et al. Risk assessment for metachronous colorectal cancer: A new post-polypectomy surveillance proposal. Gut. 2005;54(11):1572-1578. 11. Takamaru H, Yamamoto H. Colorectal Endoscopic Submucosal Dissection: Technical Advances and Prospects. Clinical Endoscopy. 2021;54(3):326-333. 12. Morgan E, Arnold M, Gini A, Lorenzoni V, Cabasag CJ, Laversanne M, Vignat J, Ferlay J, Murphy N, Bray F. Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN. Gut. 2023 Feb;72(2):338-344. doi: 10.1136/gutjnl-2022-327736. Epub 2022 Sep 8. PMID: 36604116. 13. Joaquín Cubiella Fernández, Mercé Marzo Castillejo, Juan José Mascort Roca. Diagnóstico y prevención del cáncer colorrectal 2020. Guía práctica clínica [Internet]. 2018 [cited 2021 Dec 5]; Available from: https://www.semfyc.es/wp-content/uploads/2019/01/Actualizacion_Prevencion_ cancer_colorrectal_Semfyc.pdf 14. Kudo, S. ei, Lambert, R., Allen, J. I., Fujii, H., Fujii, T., Kashida, H., … HurLELone, P. D. (2008). Nonpolypoid neoplastic lesions of the colorectal mucosa. Gastrointestinal Endoscopy, 68(4), S3–S47.doi:10.1016/j.gie.2008.07.05 15. Li Y, Zhang Y, Chen Y, Wang Y, Dou L, Wang X, et al. Long-term outcomes of endoscopic treatment for colorectal laterally spreading tumor: a large-scale multicenter retrospective study from China. Surgical Endoscopy. 2021 Feb 19;35(2). 16. Saénz R, Salazar E. El pólipo plano: un desafío. Gastroenterología Latinoamericana. 2016;27:37–43. 17. Facciorusso A, Antonino M, Di Maso M, Barone M, Muscatiello N. Non-polypoid colorectal neoplasms: classification, therapy and follow-up. World J Gastroenterol. 2015;21:5149-5157 18. Oka S, Tanaka S, Kanao H, Oba S, Chayama K. Therapeutic strategy forcolorectal laterally spreading tumor. Dig Endosc 2009; 21 (Suppl 1):S43–S46. 19. Uraoka T, Saito Y, Matsuda T, Ikehara H, Gotoda T, Saito D, Fujii T.Endoscopic indications for endoscopic mucosal resection of laterally spreading tumours in the colorectum. Gut 2006; 55:1592–1597. 20. Tanaka S, Oka S, Kaneko I, Hirata M, Mouri R, Kanao H, et al. Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization. Gastrointest Endosc 2007; 66:100–107. 21. Toyonaga T, Man-I M, Morita Y, Sanuki T, Yoshida M, Kutsumi H, et al. The new resources of treatment for early stage colorectal tumors: EMR with small incision and simplified endoscopic submucosal dissection. Dig Endosc 2009; 21 (Suppl 1):S31–S37. 22. Tutticci N, Bourke MJ. Advanced endoscopic resection in the colon: Recent innovations, current limitations and future directions. Expert Rev Gastroenterol Hepatol. 2014 Feb;8(2):161–77. 23. Saito Y, Fujii T, Kondo H, Mukai H, Yokota T, Kozu T, et al. Endoscopic treatment for laterally spreading tumors in the colon. Endoscopy. 2001;33(8):682–6. 24. H.-B. Ni, F.-Y. Wang, J. Xu, X.-J. He, J. Chen, Q. Wu, J.-F. Wu, Y.-S. Sun Screening and identification of a tumor specific methylation phenotype in the colorectal laterally spreading tumor 25. Mukawa K, Fujii S, Takeda J, Kitajima K, Tominaga K, Chibana Y, et al. Analysis of K-ras mutations and expression of cyclooxygenase-2 and gastrin protein in laterally spreading tumors. J Gastroenterol Hepatol 2005; 20:1584–1590 26. Lambert, R., & Tanaka, S. (2012). Laterally spreading tumors in the colon and rectum. European Journal of Gastroenterology & Hepatology, 24(10), 1123–1134. doi:10.1097/meg.0b013e328355e2d 27. Hiraoka S, Kato J, Tatsukawa M, Harada K, Fujita H, Morikawa T, et al. Laterally spreading type of colorectal adenoma exhibits a unique methylation phenotype and K-ras mutations. Gastroenterology 2006; 131:379–389. 28. Kurahashi T, Kaneko K, Makino R, Mitamura K. Colorectal carcinoma with special reference to growth pattern classifications: clinicopathologic characteristics and genetic changes. J Gastroenterol 2002; 37:354–362. 29. Rotondano G, Bianco MA, Buffoli F, Gizzi G, Tessari F, Cipolletta L, et al. The Cooperative Italian FLIN Study Group: prevalence and clinico-pathological features of colorectal laterally spreading tumors. Endoscopy 2011; 43: 856–861. 30. Baxter NN, Goldwasser MA, Paszat LF, Saskin R, Urbach DR, Rabeneck L, et al. Association of colonoscopy and death from colorectal cancer. Ann Intern Med 2009; 150:1–8. 31. Shen, X., Zhang, Y., Zhao, Y., Li, X., Ge, Z., Xiong, H., … Fang, J. (2020). The Coexistence of Colorectal Polyps in the Right Colon Increases the Malignant Risk of Laterally Spreading Tumors. Gastroenterology Research and Practice, 2020, 1–8. doi:10.1155/2020/3180420 32. Dornblaser, D. , Young, S. & Shaukat, A. (2024). Colon polyps: updates in classification and management. Current Opinion in Gastroenterology, 40 (1), 14-20. doi: 10.1097/MOG.0000000000000988. 33. Raju GS, Lum PJ, Ross WA, Thirumurthi S, Miller E, Lynch PM, et al. Outcome of EMR as an alternative to surgery in patients with complex colon polyps. Gastrointest Endosc . 2016;84:315.325. [ Links ] 34. Zhan T, Hielscher T, Hahn F, Hauf C, Betge J, Ebert MP, Belle S. Risk factors for local recurrence of large, flat colorectal polyps after endoscopic mucosal resection. Digestion. 2016;93:311-7. 35. Albéniz, E., Pellisé, M., Gimeno García, A. Z., Lucendo, A. J., Alonso Aguirre, P. A., Herreros de Tejada, A., … López Rosés, L. (2018). Guía clínica para la resección mucosa endoscópica de lesiones colorrectales no pediculadas. Gastroenterología y Hepatología, 41(3), 175–190. 36. Moss A, Bourke MJ, Williams SJ, Hourigan LF, Brown G, Tam W, et al. Endoscopic mucosal resection outcomes and prediction of submucosal cancer from advanced colonic mucosal neoplasia. Gastroenterology. 2011;140:1909---18 37. Masci E, Viale E, Notaristefano C, Mangiavillano B, Fiori G, Crosta C, et al. Endoscopic mucosal resection in high- and low volume centers: A prospective multicentric study. Surg Endosc. 2013;27:3799---805. 5. 38. Kaku E, Oda Y, Murakami Y, Goto H, Tanaka T, Hasuda K, et al. (2011) Proportion of flat- and depressed-type and laterally spreading tumor among advanced colorectal neoplasia. Clin Gastroenterol Hepatol 9: 503–508. https://doi.org/10.1016/j.cgh.2011.03.018 PMID: 21440090 39. Von Karsa L, Patnick J, Segnan N, Atkin W, Halloran S, Lansdorp-Vogelaar I, et al. European guidelines for quality assurance in colorectal cancer screening and diagnosis: Overview and introduction to the full Supplement publication. Endoscopy [Internet]. 2013 [cited 2022 Mar 5];45(1):51. Available from: https:// www.ncbi.nlm.nih.gov/pmc/journals/120/ 40. González M, Aravena T, Menéndez Á, Sepúlveda G, Baeza F, Brandi F, et al. Tumores de colon de expansión lateral: características en nuestra población. Gastroenterol Latinoam. 2011;22(2):86-90. 41. Xu M, Wu J, Wang C, Huo J, Lü L. [Clinicopathological differences in laterally spreading tumors between rectum and colon]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Feb 28;43(2):192-197. Chinese. doi: 10.11817/j.issn.1672-7347.2018.02.015. PMID: 29559605. 42. Ishigaki T, Kudo SE, Miyachi H, Hayashi T, Minegishi Y, Toyoshima N, Misawa M, Mori Y, Kudo T, Wakamura K, Baba T, Sawada N, Ishida F, Hamatani S. Treatment policy for colonic laterally spreading tumors based on each clinicopathologic feature of 4 subtypes: actual status of pseudo-depressed type. Gastrointest Endosc. 2020 Nov;92(5):1083-1094.e6. doi: 10.1016/j.gie.2020.04.033. Epub 2020 Apr 23. PMID: 32335123. 43. Atkin WS, Valori R, Kuipers EJ, Hoff G, Senore C, Segnan N, et al. European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition--Colonoscopic surveillance following adenoma removal. Endoscopy [Internet]. 2012 [cited 2021 Dec 5];44 Suppl 3(SUPPL3). Available from: https://pubmed.ncbi.nlm.nih. gov/23012119/ 44. Russo, P., Barbeiro, S., Awadie, H., Libânio, D., Dinis-Ribeiro, M., & Bourke, M. (2019). Management of colorectal laterally spreading tumors: a systematic review and meta-analysis. Endoscopy International Open, 07(02), E239–E259.doi:10.1055/a-0732-487
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spelling	Carrera Siachoque, Javier AlejandroPeña, Fernando YaacovPedraza Ciro, MauricioCarrera Siachoque, Javier AlejandroGarcia Duperly, RafaelCabrera Vargas, Luis FelipePérez Rivera, Carlos JosePedraza Ciro, Mauricio [0000-0001-8726-5578]2024-07-25T19:51:54Z2024-07-25T19:51:54Z2024-06https://hdl.handle.net/20.500.12495/12735instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coObjetivos: Describir y correlacionar los hallazgos clínicos y patológicos de pacientes con LEL de colón manejados con mucosectomía endoscópica en el Centro de coloproctología y Endoscopia (CCE) entre los años 2015 a 2022, en Bogotá DC, Colombia. Materiales y métodos: Estudio observacional de pacientes con lesiones de extensión lateral de colon que fueron llevados a manejo endoscópico con mucosectomía endoscópica. Se recopilaron datos clínicos, endoscópicos y patológicos de los pacientes, así como detalles sobre las técnicas endoscópicas utilizadas en su evaluación y tratamiento. Se realizó un análisis con pruebas de normalidad (Shapiro Wilk o Kolmogorov Smirnov) Resultados: De 8400 colonoscopias realizadas se identificaron 170 LEL de colon, 91 (55%) correspondieron al género masculino. La edad presento media 64 años RIQ(55 -70) años. La localización más frecuente fue el colon proximal 118(69,4 %) . Dentro de las características histológicas fue más prevalente la displasia bajo grado 128 (75,3%). El grupo de tamaño que mas se presento fue el de 20 a 29 mm en el 90(53 %), de 30 a 39 mm el 45(26,4) % y de 40 a 49 mm en el 20(11,8) %. La característica morfológica más prevalente fueron las lesiones granulares 141(83%) Conclusiones: Las LEL se presentan en un 2.9% de la poblacion estudiada, con mayor frecuencia en el colon proximal. Sus caracteres morfologicas estan dadas por tamaño de lesion de 20 a 40 mm de diámetro. El grado de displasia con mas frecuencia fue el bajo grado.Centro de Coloproctologia y EndoscopiaEspecialista en Cirugía GeneralEspecializaciónObjectives: Describe and correlate the clinical and pathological findings of patients with colonic lateral spreading tumor (LST) managed with endoscopic mucosectomy at the Centro de Coloproctologia y Endoscopia between the years 2015 to 2022, at Bogotá DC, Colombia. Materials and Methods: Retrospective study of patients with colonic lateral spreading tumors underwent endoscopic management with mucosectomy. Clinical, endoscopic, and pathological data of the patients were collected, as well as details on the endoscopic techniques used in their evaluation and treatment. An analysis was performed using tests of normality (Shapiro-Wilk or Kolmogorov-Smirnov). Results: Of 8400 colonoscopies performed, 170 LST of the colon were identified, 91 (55%) corresponded to the male gender. The present average age is 64 years IQR (55 -70) years. The most frequent location was the proximal colon 118 (69.4%). Among the histological characteristics, low grade dysplasia 128 (75.3%) was most prevalent. The size group that most occurred was 20 to 29 mm in 90 (53%), 30 to 39 mm in 45 (26.4) % and 40 to 49 mm in 20 (11.8). %. The most prevalent morphological characteristic was granular lesions 141 (83%) Conclusions: LST occur in 2.9% of the studied population, most frequently in the proximal colon. Its morphological characters are given by lesion size of 20 to 40 mm in diameter. The most common grade of dysplasia was low grade.application/pdfAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Acceso abiertohttps://purl.org/coar/access_right/c_abf2http://purl.org/coar/access_right/c_abf2Pólipos del ColonColonoscopíaNeoplasias ColorrectalesResección Endoscópica de la MucosaColon PolypsColonoscopyColorectal NeoplasmsEndoscopic Mucosal ResectionWO 100Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombianaCorrelation between endoscopic findings and pathologies of lateral extension lesions of the colon, in a colombian populationEspecialización en Cirugía GeneralUniversidad El BosqueFacultad de MedicinaTesis/Trabajo de grado - Monografía - Especializaciónhttps://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesishttps://purl.org/coar/version/c_ab4af688f83e57aa1. Morgan E, Arnold M, Gini A, Lorenzoni V, Cabasag CJ, Laversanne M, Vignat J, Ferlay J, Murphy N, Bray F. Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN. Gut. 2023 Feb;72(2):338-344. doi: 10.1136/gutjnl-2022-327736. Epub 2022 Sep 8. PMID: 36604116.2. The Global Cancer Observatory - All Rights Reserved, December, 2020. https://gco.iarc.fr/today/data/factsheets/cancers/10_8_9-Colorectum-fact-sheet.pdf3. Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023 Jan;73(1):17-48. doi: 10.3322/caac.21763. PMID: 36633525.4. Pardo C, Cendales R. Cancer incidence estimates and mortality for the top five cancer in Colombia, 2007-2011. Colomb Med (Cali). 2018 Mar 30;49(1):16-22. doi: 10.25100/cm.v49i1.3596. PMID: 29983460; PMCID: PMC60188175. Landin MD, Guerrón AD. Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection. Surg Clin North Am. 2020 Dec;100(6).6. The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach and colon. Gastrointest Endosc. 2003;58(Suppl 6):S3-S43.7. Pidala MJ, Cusick MV. The Difficult Colorectal Polyp. Surg Clin North Am. 2017 Jun;97(3):515-527.8. Muto T, Kamiya J, Atkin S. Small ”flat adenomas” of the large bowel with special references to its clinic-pathologic features. Dis Colon Rectum. 1985 Dec;28(12):847-851.9. Myung DS, Kweon SS, Lee J, Shin IS, Kim SW, Seo GS, Kim HS, Joo YE. Clinicopathological features of laterally spreading colorectal tumors and their association with advanced histology and invasiveness: An experience from Honam province of South Korea: A Honam Association for the Study of Intestinal Diseases (HASID). PLoS One. 2017 Oct 4;12(10):e0184205. doi: 10.1371/journal.pone.0184205. PMID: 28977010; PMCID: PMC5627894.10. Watabe H, Yamaji Y, Okamoto M, et al. Risk assessment for metachronous colorectal cancer: A new post-polypectomy surveillance proposal. Gut. 2005;54(11):1572-1578.11. Takamaru H, Yamamoto H. Colorectal Endoscopic Submucosal Dissection: Technical Advances and Prospects. Clinical Endoscopy. 2021;54(3):326-333.12. Morgan E, Arnold M, Gini A, Lorenzoni V, Cabasag CJ, Laversanne M, Vignat J, Ferlay J, Murphy N, Bray F. Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN. Gut. 2023 Feb;72(2):338-344. doi: 10.1136/gutjnl-2022-327736. Epub 2022 Sep 8. PMID: 36604116.13. Joaquín Cubiella Fernández, Mercé Marzo Castillejo, Juan José Mascort Roca. Diagnóstico y prevención del cáncer colorrectal 2020. Guía práctica clínica [Internet]. 2018 [cited 2021 Dec 5]; Available from: https://www.semfyc.es/wp-content/uploads/2019/01/Actualizacion_Prevencion_ cancer_colorrectal_Semfyc.pdf14. Kudo, S. ei, Lambert, R., Allen, J. I., Fujii, H., Fujii, T., Kashida, H., … HurLELone, P. D. (2008). Nonpolypoid neoplastic lesions of the colorectal mucosa. Gastrointestinal Endoscopy, 68(4), S3–S47.doi:10.1016/j.gie.2008.07.0515. Li Y, Zhang Y, Chen Y, Wang Y, Dou L, Wang X, et al. Long-term outcomes of endoscopic treatment for colorectal laterally spreading tumor: a large-scale multicenter retrospective study from China. Surgical Endoscopy. 2021 Feb 19;35(2).16. Saénz R, Salazar E. El pólipo plano: un desafío. Gastroenterología Latinoamericana. 2016;27:37–43.17. Facciorusso A, Antonino M, Di Maso M, Barone M, Muscatiello N. Non-polypoid colorectal neoplasms: classification, therapy and follow-up. World J Gastroenterol. 2015;21:5149-515718. Oka S, Tanaka S, Kanao H, Oba S, Chayama K. Therapeutic strategy forcolorectal laterally spreading tumor. Dig Endosc 2009; 21 (Suppl 1):S43–S46.19. Uraoka T, Saito Y, Matsuda T, Ikehara H, Gotoda T, Saito D, Fujii T.Endoscopic indications for endoscopic mucosal resection of laterally spreading tumours in the colorectum. Gut 2006; 55:1592–1597.20. Tanaka S, Oka S, Kaneko I, Hirata M, Mouri R, Kanao H, et al. Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization. Gastrointest Endosc 2007; 66:100–107.21. Toyonaga T, Man-I M, Morita Y, Sanuki T, Yoshida M, Kutsumi H, et al. The new resources of treatment for early stage colorectal tumors: EMR with small incision and simplified endoscopic submucosal dissection. Dig Endosc 2009; 21 (Suppl 1):S31–S37.22. Tutticci N, Bourke MJ. Advanced endoscopic resection in the colon: Recent innovations, current limitations and future directions. Expert Rev Gastroenterol Hepatol. 2014 Feb;8(2):161–77.23. Saito Y, Fujii T, Kondo H, Mukai H, Yokota T, Kozu T, et al. Endoscopic treatment for laterally spreading tumors in the colon. Endoscopy. 2001;33(8):682–6.24. H.-B. Ni, F.-Y. Wang, J. Xu, X.-J. He, J. Chen, Q. Wu, J.-F. Wu, Y.-S. Sun Screening and identification of a tumor specific methylation phenotype in the colorectal laterally spreading tumor25. Mukawa K, Fujii S, Takeda J, Kitajima K, Tominaga K, Chibana Y, et al. Analysis of K-ras mutations and expression of cyclooxygenase-2 and gastrin protein in laterally spreading tumors. J Gastroenterol Hepatol 2005; 20:1584–159026. Lambert, R., & Tanaka, S. (2012). Laterally spreading tumors in the colon and rectum. European Journal of Gastroenterology & Hepatology, 24(10), 1123–1134. doi:10.1097/meg.0b013e328355e2d27. Hiraoka S, Kato J, Tatsukawa M, Harada K, Fujita H, Morikawa T, et al. Laterally spreading type of colorectal adenoma exhibits a unique methylation phenotype and K-ras mutations. Gastroenterology 2006; 131:379–389.28. Kurahashi T, Kaneko K, Makino R, Mitamura K. Colorectal carcinoma with special reference to growth pattern classifications: clinicopathologic characteristics and genetic changes. J Gastroenterol 2002; 37:354–362.29. Rotondano G, Bianco MA, Buffoli F, Gizzi G, Tessari F, Cipolletta L, et al. The Cooperative Italian FLIN Study Group: prevalence and clinico-pathological features of colorectal laterally spreading tumors. Endoscopy 2011; 43: 856–861.30. Baxter NN, Goldwasser MA, Paszat LF, Saskin R, Urbach DR, Rabeneck L, et al. Association of colonoscopy and death from colorectal cancer. Ann Intern Med 2009; 150:1–8.31. Shen, X., Zhang, Y., Zhao, Y., Li, X., Ge, Z., Xiong, H., … Fang, J. (2020). The Coexistence of Colorectal Polyps in the Right Colon Increases the Malignant Risk of Laterally Spreading Tumors. Gastroenterology Research and Practice, 2020, 1–8. doi:10.1155/2020/318042032. Dornblaser, D. , Young, S. & Shaukat, A. (2024). Colon polyps: updates in classification and management. Current Opinion in Gastroenterology, 40 (1), 14-20. doi: 10.1097/MOG.0000000000000988.33. Raju GS, Lum PJ, Ross WA, Thirumurthi S, Miller E, Lynch PM, et al. Outcome of EMR as an alternative to surgery in patients with complex colon polyps. Gastrointest Endosc . 2016;84:315.325. [ Links ]34. Zhan T, Hielscher T, Hahn F, Hauf C, Betge J, Ebert MP, Belle S. Risk factors for local recurrence of large, flat colorectal polyps after endoscopic mucosal resection. Digestion. 2016;93:311-7.35. Albéniz, E., Pellisé, M., Gimeno García, A. Z., Lucendo, A. J., Alonso Aguirre, P. A., Herreros de Tejada, A., … López Rosés, L. (2018). Guía clínica para la resección mucosa endoscópica de lesiones colorrectales no pediculadas. Gastroenterología y Hepatología, 41(3), 175–190.36. Moss A, Bourke MJ, Williams SJ, Hourigan LF, Brown G, Tam W, et al. Endoscopic mucosal resection outcomes and prediction of submucosal cancer from advanced colonic mucosal neoplasia. Gastroenterology. 2011;140:1909---1837. Masci E, Viale E, Notaristefano C, Mangiavillano B, Fiori G, Crosta C, et al. Endoscopic mucosal resection in high- and low volume centers: A prospective multicentric study. Surg Endosc. 2013;27:3799---805. 5.38. Kaku E, Oda Y, Murakami Y, Goto H, Tanaka T, Hasuda K, et al. (2011) Proportion of flat- and depressed-type and laterally spreading tumor among advanced colorectal neoplasia. Clin Gastroenterol Hepatol 9: 503–508. https://doi.org/10.1016/j.cgh.2011.03.018 PMID: 2144009039. Von Karsa L, Patnick J, Segnan N, Atkin W, Halloran S, Lansdorp-Vogelaar I, et al. European guidelines for quality assurance in colorectal cancer screening and diagnosis: Overview and introduction to the full Supplement publication. Endoscopy [Internet]. 2013 [cited 2022 Mar 5];45(1):51. Available from: https:// www.ncbi.nlm.nih.gov/pmc/journals/120/40. González M, Aravena T, Menéndez Á, Sepúlveda G, Baeza F, Brandi F, et al. Tumores de colon de expansión lateral: características en nuestra población. Gastroenterol Latinoam. 2011;22(2):86-90.41. Xu M, Wu J, Wang C, Huo J, Lü L. [Clinicopathological differences in laterally spreading tumors between rectum and colon]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 Feb 28;43(2):192-197. Chinese. doi: 10.11817/j.issn.1672-7347.2018.02.015. PMID: 29559605.42. Ishigaki T, Kudo SE, Miyachi H, Hayashi T, Minegishi Y, Toyoshima N, Misawa M, Mori Y, Kudo T, Wakamura K, Baba T, Sawada N, Ishida F, Hamatani S. Treatment policy for colonic laterally spreading tumors based on each clinicopathologic feature of 4 subtypes: actual status of pseudo-depressed type. Gastrointest Endosc. 2020 Nov;92(5):1083-1094.e6. doi: 10.1016/j.gie.2020.04.033. Epub 2020 Apr 23. PMID: 32335123.43. Atkin WS, Valori R, Kuipers EJ, Hoff G, Senore C, Segnan N, et al. European guidelines for quality assurance in colorectal cancer screening and diagnosis. First Edition--Colonoscopic surveillance following adenoma removal. Endoscopy [Internet]. 2012 [cited 2021 Dec 5];44 Suppl 3(SUPPL3). Available from: https://pubmed.ncbi.nlm.nih. gov/23012119/44. Russo, P., Barbeiro, S., Awadie, H., Libânio, D., Dinis-Ribeiro, M., & Bourke, M. (2019). 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Correlación entre los hallazgos endoscopicos y patológios de lesiones de extensión lateral de colon, en población colombiana

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