Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance

Autores:
Sierra, Fernando
Gomez, Daniel
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/2066
Acceso en línea:
http://hdl.handle.net/20.500.12495/2066
https://doi.org/10.1038/s41395-018-0199-0
Palabra clave:
Activadores de enzimas
Agonistas de la guanilato ciclasa C
Mecanismos moleculares de acción farmacológica
Rights
License
Acceso cerrado
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network_name_str Repositorio U. El Bosque
repository_id_str
dc.title.spa.fl_str_mv Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance
dc.title.translated.none.fl_str_mv Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance
title Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance
spellingShingle Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance
Activadores de enzimas
Agonistas de la guanilato ciclasa C
Mecanismos moleculares de acción farmacológica
title_short Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance
title_full Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance
title_fullStr Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance
title_full_unstemmed Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance
title_sort Efficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importance
dc.creator.fl_str_mv Sierra, Fernando
Gomez, Daniel
dc.contributor.author.none.fl_str_mv Sierra, Fernando
Gomez, Daniel
dc.subject.decs.spa.fl_str_mv Activadores de enzimas
Agonistas de la guanilato ciclasa C
Mecanismos moleculares de acción farmacológica
topic Activadores de enzimas
Agonistas de la guanilato ciclasa C
Mecanismos moleculares de acción farmacológica
publishDate 2019
dc.date.issued.none.fl_str_mv 2019
dc.date.accessioned.none.fl_str_mv 2020-03-16T20:14:54Z
dc.date.available.none.fl_str_mv 2020-03-16T20:14:54Z
dc.type.spa.fl_str_mv article
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dc.type.local.spa.fl_str_mv artículo
dc.identifier.issn.none.fl_str_mv 0002-9270
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/2066
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1038/s41395-018-0199-0
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
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identifier_str_mv 0002-9270
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url http://hdl.handle.net/20.500.12495/2066
https://doi.org/10.1038/s41395-018-0199-0
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv American Journal of Gastroenterology, 0002-9270, Vol. 114, Num. 1, 2019, p.169
dc.relation.uri.none.fl_str_mv https://journals.lww.com/ajg/fulltext/2019/01000/Efficacy_and_Tolerability_of_Guanylate_Cyclase_C.26.aspx
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.local.spa.fl_str_mv Acceso cerrado
dc.rights.accessrights.none.fl_str_mv http://purl.org/coar/access_right/c_abf318
dc.rights.creativecommons.none.fl_str_mv 2019
rights_invalid_str_mv Acceso cerrado
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2019
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dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Lippincott, Williams & Wilkins
dc.publisher.journal.spa.fl_str_mv American Journal of Gastroenterology
institution Universidad El Bosque
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spelling Sierra, FernandoGomez, Daniel2020-03-16T20:14:54Z2020-03-16T20:14:54Z20190002-9270http://hdl.handle.net/20.500.12495/2066https://doi.org/10.1038/s41395-018-0199-0instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coapplication/pdfengLippincott, Williams & WilkinsAmerican Journal of GastroenterologyAmerican Journal of Gastroenterology, 0002-9270, Vol. 114, Num. 1, 2019, p.169https://journals.lww.com/ajg/fulltext/2019/01000/Efficacy_and_Tolerability_of_Guanylate_Cyclase_C.26.aspxEfficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importanceEfficacy and tolerability of guanylate cyclase-C agonist: encouraging results with insignificant clinical importancearticleartículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Activadores de enzimasAgonistas de la guanilato ciclasa CMecanismos moleculares de acción farmacológicaAcceso cerradohttp://purl.org/coar/access_right/c_abf3182019http://purl.org/coar/access_right/c_abf2THUMBNAILSierra, Fernando.pdf.jpgSierra, Fernando.pdf.jpgimage/jpeg5775https://repositorio.unbosque.edu.co/bitstreams/3a2acc72-6787-4927-bd8e-31a4f80a7446/download7210a811635d1799e7c05fee5d259be7MD53LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/063aeaa1-143c-4ef5-b3aa-d70e2a65a3da/download8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALSierra, Fernando.pdfSierra, Fernando.pdfapplication/pdf82102https://repositorio.unbosque.edu.co/bitstreams/4372cb3a-cb6e-4c47-9be4-e6820a09d155/downloadee3dc5b8da53e4cee570ebb3dc103106MD51TEXTSierra, Fernando.pdf.txtSierra, Fernando.pdf.txtExtracted texttext/plain5352https://repositorio.unbosque.edu.co/bitstreams/c6b4162a-cf73-4fd1-95aa-0b5ceba43f59/download6b993d966e864640e6d93ddb04e4f323MD5420.500.12495/2066oai:repositorio.unbosque.edu.co:20.500.12495/20662024-02-07 12:08:04.711restrictedhttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.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