Bioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en peces
Se examinó la presencia de tres grupos de antibióticos (penicilinas, sulfonamidas y fluoroquinolonas) en peces mediante diversas técnicas cromatográficas. Para las penicilinas, se encontró únicamente un estudio que detectó amoxicilina en músculo de peces utilizando HPLC-MS/MS, en las sulfonamidas y...
- Autores:
-
Escudero Romero, Cielo Julieth
Becerra Figueroa, Liliana Marcela
- Tipo de recurso:
- https://purl.org/coar/resource_type/c_7a1f
- Fecha de publicación:
- 2024
- Institución:
- Universidad El Bosque
- Repositorio:
- Repositorio U. El Bosque
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unbosque.edu.co:20.500.12495/12119
- Acceso en línea:
- https://hdl.handle.net/20.500.12495/12119
- Palabra clave:
- Bioacumulación
Penicilinas
Sulfonamidas
Fluoroquinolonas
Cromatografía líquida
Espectrofotometría de masas
Toxicidad
615.19
Bioaccumulation
Penicillins
Sulfonamides
Fluoroquinolones
Liquid chromatography
Mass spectrophotometry
Toxicity
- Rights
- openAccess
- License
- Atribución-NoComercial-CompartirIgual 4.0 Internacional
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| dc.title.none.fl_str_mv |
Bioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en peces |
| dc.title.translated.none.fl_str_mv |
Bioaccumulation of penicillins, sulfonamides and fluoroquinolones in fish: A literature review of analytical methods for their detection, description of biotransformation and toxicity in fish |
| title |
Bioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en peces |
| spellingShingle |
Bioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en peces Bioacumulación Penicilinas Sulfonamidas Fluoroquinolonas Cromatografía líquida Espectrofotometría de masas Toxicidad 615.19 Bioaccumulation Penicillins Sulfonamides Fluoroquinolones Liquid chromatography Mass spectrophotometry Toxicity |
| title_short |
Bioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en peces |
| title_full |
Bioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en peces |
| title_fullStr |
Bioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en peces |
| title_full_unstemmed |
Bioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en peces |
| title_sort |
Bioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en peces |
| dc.creator.fl_str_mv |
Escudero Romero, Cielo Julieth Becerra Figueroa, Liliana Marcela |
| dc.contributor.advisor.none.fl_str_mv |
Becerra Figueroa, Liliana Marcela |
| dc.contributor.author.none.fl_str_mv |
Escudero Romero, Cielo Julieth Becerra Figueroa, Liliana Marcela |
| dc.contributor.orcid.none.fl_str_mv |
Escudero Romero, Cielo Julieth [0009-0003-3286-8293] Becerra Figueroa, Liliana Marcela [0000-0002-0459-3419] |
| dc.subject.none.fl_str_mv |
Bioacumulación Penicilinas Sulfonamidas Fluoroquinolonas Cromatografía líquida Espectrofotometría de masas Toxicidad |
| topic |
Bioacumulación Penicilinas Sulfonamidas Fluoroquinolonas Cromatografía líquida Espectrofotometría de masas Toxicidad 615.19 Bioaccumulation Penicillins Sulfonamides Fluoroquinolones Liquid chromatography Mass spectrophotometry Toxicity |
| dc.subject.ddc.none.fl_str_mv |
615.19 |
| dc.subject.keywords.none.fl_str_mv |
Bioaccumulation Penicillins Sulfonamides Fluoroquinolones Liquid chromatography Mass spectrophotometry Toxicity |
| description |
Se examinó la presencia de tres grupos de antibióticos (penicilinas, sulfonamidas y fluoroquinolonas) en peces mediante diversas técnicas cromatográficas. Para las penicilinas, se encontró únicamente un estudio que detectó amoxicilina en músculo de peces utilizando HPLC-MS/MS, en las sulfonamidas y fluoroquinolonas, predominó el uso de HPLC-MS/MS, UPLC-MS/MS y LC-MS/MS, en diversos tejidos de peces. Los procedimientos de preparación de muestras y las condiciones cromatográficas fueron muy similares entre estos grupos, el analizador de masas principal fue triple cuadrupolo acoplado a MRM, con fuentes de ionización ESI y API. Con relación a la bioacumulación, la ciprofloxacina mostró la mayor presencia entre las múltiples especies. La sulfadiazina también presentó altos niveles de bioacumulación, mientras que el sulfametoxazol y la Norfloxacina tuvieron una presencia moderada pero el LogBAF más alto (5,3). Las especies con mayor bioacumulación fueron las carpas, y los sitios más afectados fueron el río Amarillo y Mahegang, China, las branquias fue el tejido con la mayor bioacumulación, no se observó una relación significativa entre el coeficiente de reparto octanol-agua (Log P) y el factor de bioacumulación (log BAF). |
| publishDate |
2024 |
| dc.date.accessioned.none.fl_str_mv |
2024-05-15T18:39:28Z |
| dc.date.available.none.fl_str_mv |
2024-05-15T18:39:28Z |
| dc.date.issued.none.fl_str_mv |
2024-05 |
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http://purl.org/coar/resource_type/c_7a1f |
| dc.type.local.none.fl_str_mv |
Tesis/Trabajo de grado - Monografía - Pregrado |
| dc.type.coar.none.fl_str_mv |
https://purl.org/coar/resource_type/c_7a1f |
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info:eu-repo/semantics/bachelorThesis |
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https://purl.org/coar/version/c_ab4af688f83e57aa |
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https://purl.org/coar/resource_type/c_7a1f |
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https://hdl.handle.net/20.500.12495/12119 |
| dc.identifier.instname.spa.fl_str_mv |
Universidad El Bosque |
| dc.identifier.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional Universidad El Bosque |
| dc.identifier.repourl.none.fl_str_mv |
repourl:https://repositorio.unbosque.edu.co |
| url |
https://hdl.handle.net/20.500.12495/12119 |
| identifier_str_mv |
Universidad El Bosque reponame:Repositorio Institucional Universidad El Bosque repourl:https://repositorio.unbosque.edu.co |
| dc.language.iso.fl_str_mv |
spa |
| language |
spa |
| dc.relation.references.none.fl_str_mv |
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Zhang et al., «Subchronic toxicity of dietary sulfamethazine and nanoplastics in marine medaka (Oryzias melastigma): Insights from the gut microbiota and intestinal oxidative status», Ecotoxicol Environ Saf, vol. 226, 2021, p. 112820. R. Oliveira, S. McDonough, J. C. L. Ladewig, A. M. V. M. Soares, A. J. A. Nogueira, y I. Domingues, «Effects of oxytetracycline and amoxicillin on development and biomarkers activities of zebrafish (Danio rerio) », Environ Toxicol Pharmacol, vol. 36, n.o 3, 2013, pp. 903-912. C. L. Gonçalves et al., «Exposure to a high dose of amoxicillin causes behavioral changes and oxidative stress in young zebrafish», Metab Brain Dis, vol. 35, n.o 8, 2020, pp. 1407-141. K. L. Deprey y J. K. Uno, «Amoxicillin decreases intestinal microbial diversity and increases stress-associated behaviors in zebrafish», The FASEB Journal, vol. 30, n.o S1, 2016 pp. 1027.7-1027.7. R. Rao, B. Manu, y A. K. 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Rodriguez-Mozaz et al., «Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river», Water Res, vol. 69, 2015, pp. 234-242. |
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Becerra Figueroa, Liliana MarcelaEscudero Romero, Cielo JuliethBecerra Figueroa, Liliana MarcelaEscudero Romero, Cielo Julieth [0009-0003-3286-8293]Becerra Figueroa, Liliana Marcela [0000-0002-0459-3419]2024-05-15T18:39:28Z2024-05-15T18:39:28Z2024-05https://hdl.handle.net/20.500.12495/12119Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coSe examinó la presencia de tres grupos de antibióticos (penicilinas, sulfonamidas y fluoroquinolonas) en peces mediante diversas técnicas cromatográficas. Para las penicilinas, se encontró únicamente un estudio que detectó amoxicilina en músculo de peces utilizando HPLC-MS/MS, en las sulfonamidas y fluoroquinolonas, predominó el uso de HPLC-MS/MS, UPLC-MS/MS y LC-MS/MS, en diversos tejidos de peces. Los procedimientos de preparación de muestras y las condiciones cromatográficas fueron muy similares entre estos grupos, el analizador de masas principal fue triple cuadrupolo acoplado a MRM, con fuentes de ionización ESI y API. Con relación a la bioacumulación, la ciprofloxacina mostró la mayor presencia entre las múltiples especies. La sulfadiazina también presentó altos niveles de bioacumulación, mientras que el sulfametoxazol y la Norfloxacina tuvieron una presencia moderada pero el LogBAF más alto (5,3). Las especies con mayor bioacumulación fueron las carpas, y los sitios más afectados fueron el río Amarillo y Mahegang, China, las branquias fue el tejido con la mayor bioacumulación, no se observó una relación significativa entre el coeficiente de reparto octanol-agua (Log P) y el factor de bioacumulación (log BAF).PregradoQuímico FarmacéuticoThe presence of three groups of antibiotics (penicillins, sulfonamides and fluoroquinolones) in fish was examined by various chromatographic techniques. For penicillins, only one study was found that detected amoxicillin in fish muscle using HPLC-MS/MS; for sulfonamides and fluoroquinolones, the use of HPLC-MS/MS, UPLC-MS/MS and LC-MS/MS predominated in various fish tissues. Sample preparation procedures and chromatographic conditions were very similar among these groups, the main mass analyzer was triple quadrupole coupled to MRM, with ESI and API ionization sources. Regarding bioaccumulation, ciprofloxacin showed the highest presence among the multiple species. Sulfadiazine also showed high levels of bioaccumulation, while sulfamethoxazole and Norfloxacin had a moderate presence but the highest LogBAF (5.3). The species with the highest bioaccumulation were carp, and the most affected sites were the Yellow River and Mahegang, China, the gills was the tissue with the highest bioaccumulation, no significant relationship was observed between the octanol-water partition coefficient (Log P) and the bioaccumulation factor (log BAF).application/pdfAtribución-NoComercial-CompartirIgual 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-sa/4.0/Acceso abiertoinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2BioacumulaciónPenicilinasSulfonamidasFluoroquinolonasCromatografía líquidaEspectrofotometría de masasToxicidad615.19BioaccumulationPenicillinsSulfonamidesFluoroquinolonesLiquid chromatographyMass spectrophotometryToxicityBioacumulación de penicilinas, sulfamidas y fluoroquinolonas en peces: Una revisión bibliográfica de métodos analíticos para su detección, descripción de la biotransformación y toxicidad en pecesBioaccumulation of penicillins, sulfonamides and fluoroquinolones in fish: A literature review of analytical methods for their detection, description of biotransformation and toxicity in fishQuímica FarmacéuticaUniversidad El BosqueFacultad de CienciasTesis/Trabajo de grado - Monografía - Pregradohttps://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesishttps://purl.org/coar/version/c_ab4af688f83e57aaN. Nassar, S. Kasapis, S. Pyreddy, and T. Istivan, “The History of Antibiotics Illumes the Future of Antimicrobial Peptides Administered Through Nanosystems,” Nanotechnology. Life Sci., 2022, pp. 1–74.F. De y H. A. Lopardo, «Antibióticos Clasificación, estructura, mecanismos de acción y resistencia Libros de Cátedra», La plata, 2020.Van Boeckel et al., «Reducing antimicrobial use in food animals», Science, vol. 357, n. o 6358. AAAS, 2017. pp. 1350-1352.T. Hu et al., «Bioaccumulation and trophic transfer of antibiotics in the aquatic and terrestrial food webs of the Yellow River Delta», Chemosphere, vol. 323, 2023.A. Qadeer et al., «Influence of habitats and physicochemical factors on trophic transfer processes of antibiotics in a freshwater ecosystem: Application of stable isotopes and human health risks», STOTEN, vol. 863, 2023.P. Kovalakova, L. Cizmas, T. J. McDonald, B. Marsalek, M. Feng, y V. K. 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Yang, «Bioavailability and trophic magnification of antibiotics in aquatic food webs of Pearl River, China: Influence of physicochemical characteristics and biotransformation», Sci. Total Environ, vol. 820, 2022, p. 153285.32. National Center for Biotechnology Information, «PubChem Compound Summary for CID 5323, Sulfadimethoxine», 2024.National Center for Biotechnology Information, «PubChem Compound Summary for CID 5336, Sulfapyridine. », 2024.National Center for Biotechnology Information, «PubChem Compound Summary for CID 4539, Norfloxacin. », 2024.S. Liu, G. Dong, H. Zhao, M. Chen, W. Quan, y B. Qu, «Occurrence and risk assessment of fluoroquinolones and tetracyclines in cultured fish from a coastal region of northern China», ESPR, 2018, pp. 8035-8043.National Center for Biotechnology Information, «PubChem Compound Summary for CID 2764, Ciprofloxacin», 2024.National Center for Biotechnology Information, «PubChem Compound Summary for CID 4583, Ofloxacin», 2024.Y. Sun et al., «Enhanced bioaccumulation of fluorinated antibiotics in crucian carp (Carassius carassius): Influence of fluorine substituent», Sci. Total Environ, vol. 748, 2020.M. Zhu, J. Chen, W. J. G. M. Peijnenburg, H. Xie, Z. Wang, y S. Zhang, «Controlling factors and toxicokinetic modeling of antibiotics bioaccumulation in aquatic organisms: A review», Crit Rev Environ Sci Technol, vol. 53, n.o 15, 2023, pp. 1431-1451.H. Zhao, W. Quan, T. G. Bekele, M. Chen, X. Zhang, y B. Qu, «Effect of copper on the accumulation and elimination kinetics of fluoroquinolones in the zebrafish (Danio rerio) », Ecotoxicol Environ Saf, vol. 156, 2018, pp. 135-140.V. G. Bose y K. S. Shreenidhi, «Microbial degradation of pharmaceuticals and personal care products», Microbes Microb. Biotechnol. Green Remed., 2022, pp. 619-632.J. V. Tarazona y G. P. Dohmen, «Ecotoxicology of Rice Pesticides», Pestic. Risk Assess. Rice Paddies, 2008, pp. 69-90.N. Iftikhar, R. Zafar, y I. Hashmi, «Multi-biomarkers approach to determine the toxicological impacts of sulfamethoxazole antibiotic on freshwater fish Cyprinus carpio», Ecotoxicol Environ Saf, vol. 233, 2022, p. 113331.A. Baesu, G. Ballash, D. Mollenkopf, T. Wittum, S. M. P. Sulliván, y S. Bayen, «Suspect screening of pharmaceuticals in fish livers based on QuEChERS extraction coupled with high resolution mass spectrometry», Sci. Total Environ, vol. 783, 2021, p. 146902.Q. Wu, C. G. Pan, Y. H. Wang, S. K. Xiao, y K. F. Yu, «Antibiotics in a subtropical food web from the Beibu Gulf, South China: Occurrence, bioaccumulation and trophic transfer», Sci. Total Environ, vol. 751, 2021, p. 141718.K. Nozaki et al., «Pharmaceuticals and personal care products (PPCPs) in surface water and fish from three Asian countries: Species-specific bioaccumulation and potential ecological risks», Sci. Total Environ, vol. 866, 2023, p. 161258.H. Chen et al., «Tissue distribution, bioaccumulation characteristics and health risk of antibiotics in cultured fish from a typical aquaculture area», J Hazard Mater, vol. 343, 2018, pp. 140-148.J. Zhang et al., «Polycyclic aromatic hydrocarbons (PAHs) and antibiotics in oil-contaminated aquaculture areas: Bioaccumulation, influencing factors, and human health risks», J Hazard Mater, vol. 437, 2022, p. 129365.Q. Wu, C. G. Pan, Y. H. Wang, S. K. Xiao, y K. F. Yu, «Antibiotics in a subtropical food web from the Beibu Gulf, South China: Occurrence, bioaccumulation and trophic transfer», Sci. Total Environ, vol. 751, 2021, p. 141718.J. Guo et al., «Accumulation rates and chronologies from depth profiles of 210Pbex and 137Cs in sediments of northern Beibu Gulf, South China sea», J Environ Radioact, vol. 213, 2020, p. 106136R. Pashaei, R. Dzingelevičienė, S. Abbasi, M. Szultka-Młyńska, y B. Buszewski, «Determination of 15 human pharmaceutical residues in fish and shrimp tissues by high-performance liquid chromatography-tandem mass spectrometry», Environ Monit Assess, vol. 194, n.o 5, 2022.A. Baesu, G. Ballash, D. Mollenkopf, T. Wittum, S. M. P. Sulliván, y S. Bayen, «Suspect screening of pharmaceuticals in fish livers based on QuEChERS extraction coupled with high resolution mass spectrometry», Sci. Total Environ, vol. 783, 2022, p. 146902.H. Y. Kim, I. S. Lee, y J. E. Oh, «Human and veterinary pharmaceuticals in the marine environment including fish farms in Korea», Sci. Total Environ,vol. 579, 2017, pp. 940-949.C. Wang et al., «Ecological and human health risks of antibiotics in marine species through mass transfer from sea to land in a coastal area: A case study in Qinzhou Bay, the South China sea»,Environ Pollut, vol. 316, 2023, p. 120502.S. Zhao, X. Wang, Y. Li, y J. Lin, «Bioconcentration, metabolism, and biomarker responses in marine medaka (Oryzias melastigma) exposed to sulfamethazine», Aquatic Toxicology, vol. 181, 2016, pp. 29-36.Q.F. Han et al., «Antibiotics in marine aquaculture farms surrounding Laizhou Bay, Bohai Sea: Distribution characteristics considering various culture modes and organism species», Sci. Total Environ., vol. 760, 2021, p. 143863, 2021.P. M. Ondarza, S. P. Haddad, E. Avigliano, K. S. B. Miglioranza, y B. W. Brooks, «Pharmaceuticals, illicit drugs and their metabolites in fish from Argentina: Implications for protected areas influenced by urbanization», Sci. Total Environ, vol. 649, 2019, pp. 1029-1037.J. Wang y P. R. Gardinali, «Analysis of selected pharmaceuticals in fish and the freshwater bodies directly affected by re claimed water using liquid chromatography-tandem mass spectrometry», Anal Bioanal Chem, vol. 404, n.o 9, 2012, pp. 2711-2720.Daniel. C Harrys, «Análisis químico cuantitativo», 2016.K. 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Zheng, «Residues and health risk assessment of typical antibiotics in aquatic products from the Dongting Lake, Chin “Did you eat «Antibiotics» today?” », Environ. Sci. Pollut. Res, vol. 25, n.o 4, 2018, pp. 3913-3921.S. Rodriguez-Mozaz et al., «Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river», Water Res, vol. 69, 2015, pp. 234-242.spaCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81154https://repositorio.unbosque.edu.co/bitstreams/bc97a1f6-47a7-4235-80cc-a5c5dc555405/downloadadb7af3ef071a784ffe1b544b9a344abMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82000https://repositorio.unbosque.edu.co/bitstreams/5209c949-03e3-463d-a613-5fe59e1b74d0/download17cc15b951e7cc6b3728a574117320f9MD52Anexo 1 Acta de aprobacion.pdfapplication/pdf770852https://repositorio.unbosque.edu.co/bitstreams/7f14e0d8-0c0b-43fb-8432-b010d3e54a5b/downloade2d76290d5383f38e259856f463b3399MD517Carta de autorizacion.pdfapplication/pdf389804https://repositorio.unbosque.edu.co/bitstreams/fae2a9f1-a0cf-4245-b6e7-a5a29ef417f8/downloadac645bde39e3e4daecbecd4d55cefea2MD518ORIGINALTrabajo de grado.pdfTrabajo de 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texttext/plain101708https://repositorio.unbosque.edu.co/bitstreams/ed1867e9-71d8-45e6-9bd1-9480c5025b98/download890048f608329e3af28b42e7d187d9a6MD515THUMBNAILTrabajo de grado.pdf.jpgTrabajo de grado.pdf.jpgGenerated Thumbnailimage/jpeg5401https://repositorio.unbosque.edu.co/bitstreams/be55eabd-a60f-41a1-b29b-c36e41598d50/download0cb0c518ff8115352023e39dfe60c8bdMD51620.500.12495/12119oai:repositorio.unbosque.edu.co:20.500.12495/121192024-07-04 12:26:42.265http://creativecommons.org/licenses/by-nc-sa/4.0/Atribución-NoComercial-CompartirIgual 4.0 Internacionalopen.accesshttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El 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