Biological therapy in early rheumatoid arthritis: Efficacy in disease remission

EULAR 2010), que recibieron terapia biológica en monoterapia o combinada con otros fármacos antirreumáticos modificadores de la enfermedad (FARME) y fueron incluidos en estudios clínicos controlados aleatorizados.Resultados_ La revisión sistemática de la literatura identificó 978 estudios potencialm...

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Autores:
Camargo Barrios, Carmenza Beatriz
Villarreal Fernández, Jorge Eliécer
Quintana, Gerardo
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
spa
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/3419
Acceso en línea:
http://hdl.handle.net/20.500.12495/3419
https://doi.org/10.1016/j.rcreu.2017.04.001
https://repositorio.unbosque.edu.co
Palabra clave:
Artritis reumatoide temprana
Terapia biológica
Remisión
revisión sistemática
Mortalidad prematura
Calidad de vida
Early rheumatoid arthritis
Biological therapy
remission
Rights
openAccess
License
Acceso abierto
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network_name_str Repositorio U. El Bosque
repository_id_str
dc.title.spa.fl_str_mv Biological therapy in early rheumatoid arthritis: Efficacy in disease remission
dc.title.translated.spa.fl_str_mv Terapia biológica en la artritis reumatoide temprana: eficacia en la remisión de la enfermedad
title Biological therapy in early rheumatoid arthritis: Efficacy in disease remission
spellingShingle Biological therapy in early rheumatoid arthritis: Efficacy in disease remission
Artritis reumatoide temprana
Terapia biológica
Remisión
revisión sistemática
Mortalidad prematura
Calidad de vida
Early rheumatoid arthritis
Biological therapy
remission
title_short Biological therapy in early rheumatoid arthritis: Efficacy in disease remission
title_full Biological therapy in early rheumatoid arthritis: Efficacy in disease remission
title_fullStr Biological therapy in early rheumatoid arthritis: Efficacy in disease remission
title_full_unstemmed Biological therapy in early rheumatoid arthritis: Efficacy in disease remission
title_sort Biological therapy in early rheumatoid arthritis: Efficacy in disease remission
dc.creator.fl_str_mv Camargo Barrios, Carmenza Beatriz
Villarreal Fernández, Jorge Eliécer
Quintana, Gerardo
dc.contributor.author.none.fl_str_mv Camargo Barrios, Carmenza Beatriz
Villarreal Fernández, Jorge Eliécer
Quintana, Gerardo
dc.subject.spa.fl_str_mv Artritis reumatoide temprana
Terapia biológica
Remisión
topic Artritis reumatoide temprana
Terapia biológica
Remisión
revisión sistemática
Mortalidad prematura
Calidad de vida
Early rheumatoid arthritis
Biological therapy
remission
dc.subject.decs.spa.fl_str_mv revisión sistemática
Mortalidad prematura
Calidad de vida
dc.subject.keywords.spa.fl_str_mv Early rheumatoid arthritis
Biological therapy
remission
description EULAR 2010), que recibieron terapia biológica en monoterapia o combinada con otros fármacos antirreumáticos modificadores de la enfermedad (FARME) y fueron incluidos en estudios clínicos controlados aleatorizados.Resultados_ La revisión sistemática de la literatura identificó 978 estudios potencialmente relevantes
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-07-10T16:03:48Z
dc.date.available.none.fl_str_mv 2020-07-10T16:03:48Z
dc.date.issued.none.fl_str_mv 2020
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dc.type.local.none.fl_str_mv Artículo de revista
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dc.identifier.issn.none.fl_str_mv 2027-9000
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/3419
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.rcreu.2017.04.001
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv https://repositorio.unbosque.edu.co
identifier_str_mv 2027-9000
instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
url http://hdl.handle.net/20.500.12495/3419
https://doi.org/10.1016/j.rcreu.2017.04.001
https://repositorio.unbosque.edu.co
dc.language.iso.none.fl_str_mv spa
language spa
dc.relation.ispartofseries.spa.fl_str_mv Revista colombiana de reumatologia, 2027-9000, Vol. 24, Nro. 3, 2017, p. 164-176
dc.relation.uri.none.fl_str_mv https://www.sciencedirect.com/science/article/abs/pii/S0121812317300439?via%3Dihub
dc.rights.local.spa.fl_str_mv Acceso abierto
dc.rights.accessrights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
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dc.rights.creativecommons.none.fl_str_mv 2017-04-06
rights_invalid_str_mv Acceso abierto
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2017-04-06
eu_rights_str_mv openAccess
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Asociacion Colombiana de Reumatologia
dc.publisher.journal.spa.fl_str_mv Revista colombiana de reumatologia
institution Universidad El Bosque
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spelling Camargo Barrios, Carmenza BeatrizVillarreal Fernández, Jorge EliécerQuintana, Gerardo2020-07-10T16:03:48Z2020-07-10T16:03:48Z20202027-9000http://hdl.handle.net/20.500.12495/3419https://doi.org/10.1016/j.rcreu.2017.04.001instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquehttps://repositorio.unbosque.edu.coEULAR 2010), que recibieron terapia biológica en monoterapia o combinada con otros fármacos antirreumáticos modificadores de la enfermedad (FARME) y fueron incluidos en estudios clínicos controlados aleatorizados.Resultados_ La revisión sistemática de la literatura identificó 978 estudios potencialmente relevantesRheumatoid arthritis is a chronic, systemic inflammatory disease, with a world prevalence of around 1%. The course of the disease may be changed by using synthetic and/or biological disease-modifying antirheumatic drugs alone or in combination. This review assessed whether the use of biological agents in early rheumatoid arthritis can lead to disease remission. Objective: To evaluate the efficacy of biological therapies in inducing remission in patients with early rheumatoid arthritis. Methods: Type of study: systematic review of the literature. A systematic search of the literature was made in specialized electronic health databases: PubMed, Embase, Cochrane, LILACS, gray literature (doctoral theses, congresses, entity reports, unpublished works) and manual search (Secondary searches of the studies cited in the selected articles). Inclusion criteria: Patients older than 18 years with early rheumatoid arthritis (clinical course less than 12 months) according to criteria of the American College of Rheumatology / European League against Rheumatism (ACR 1987, ACR / EULAR 2010), who received biological therapy Monotherapy or combined with other disease modifying antirheumatic drugs (DMARDs) and were included in randomized controlled trials. Results: The systematic review of the literature identified 978 potentially relevant studies. Of the 86 that were chosen for a thorough evaluation, 68 articles were excluded. A qualitative and quantitative analysis of the remaining 18 studies was performed. A high risk of bias was identified in the studies evaluated and synthesis of the evidence did not show differences in the outcome of remission using biological therapy alone or combined with conventional DMARDs versus synthetic DMARDs (RR 1.08, 95% CI: 0.94-1.23). Conclusions: There is no difference in the outcome of remission in patients with early rheumatoid arthritis receiving biological therapy versus patients treated with conventional disease modifying antirheumatic drugsapplication/pdfspaAsociacion Colombiana de ReumatologiaRevista colombiana de reumatologiaRevista colombiana de reumatologia, 2027-9000, Vol. 24, Nro. 3, 2017, p. 164-176https://www.sciencedirect.com/science/article/abs/pii/S0121812317300439?via%3DihubArtritis reumatoide tempranaTerapia biológicaRemisiónrevisión sistemáticaMortalidad prematuraCalidad de vidaEarly rheumatoid arthritisBiological therapyremissionBiological therapy in early rheumatoid arthritis: Efficacy in disease remissionTerapia biológica en la artritis reumatoide temprana: eficacia en la remisión de la enfermedadArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abierto2017-04-06ORIGINALenza Beatriz Camargo-Barriosa , Jorge Eliécer Rivas-Ibargüena , Gerardo Quintana-Lópezb_2017.pdfenza Beatriz Camargo-Barriosa , Jorge Eliécer Rivas-Ibargüena , Gerardo Quintana-Lópezb_2017.pdfapplication/pdf756208https://repositorio.unbosque.edu.co/bitstreams/f544cc86-447d-4f5e-b02e-7ed7c45fb82f/download9723ca1b3ff17892d1a44688d99deb34MD51LICENSElicense.txtlicense.txttext/plain; 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