Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population

β-Lactam/β-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum-β-lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and the definitive therapy cohort (251 patients). The 30-day c...

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Autores:
Tamma , Pranita
Villegas, María Virginia
Tipo de recurso:
Article of journal
Fecha de publicación:
2017
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/3503
Acceso en línea:
http://hdl.handle.net/20.500.12495/3503
https://doi.org/10.1128/AAC.01094-17
https://repositorio.unbosque.edu.co
Palabra clave:
Beta-Lactamas
Inhibidores de beta-Lactamasas
Carbapenémicos
ESBLs
Bloodstream infection
Neutropenia
Rights
openAccess
License
Acceso abierto
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dc.title.spa.fl_str_mv Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population
dc.title.translated.spa.fl_str_mv Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population
title Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population
spellingShingle Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population
Beta-Lactamas
Inhibidores de beta-Lactamasas
Carbapenémicos
ESBLs
Bloodstream infection
Neutropenia
title_short Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population
title_full Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population
title_fullStr Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population
title_full_unstemmed Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population
title_sort Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient population
dc.creator.fl_str_mv Tamma , Pranita
Villegas, María Virginia
dc.contributor.author.none.fl_str_mv Tamma , Pranita
Villegas, María Virginia
dc.contributor.orcid.none.fl_str_mv Villegas, María Virginia [0000-0003-1898-9067]
dc.subject.decs.spa.fl_str_mv Beta-Lactamas
Inhibidores de beta-Lactamasas
Carbapenémicos
topic Beta-Lactamas
Inhibidores de beta-Lactamasas
Carbapenémicos
ESBLs
Bloodstream infection
Neutropenia
dc.subject.keywords.spa.fl_str_mv ESBLs
Bloodstream infection
Neutropenia
description β-Lactam/β-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum-β-lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and the definitive therapy cohort (251 patients). The 30-day case fatality rates and other secondary outcomes were similar in the two therapy groups of the two cohorts and also in the propensity-matched cohorts. BLBLIs might be carbapenem-sparing alternatives for the treatment of BSI due to ESBLs in these patients.
publishDate 2017
dc.date.issued.none.fl_str_mv 2017
dc.date.accessioned.none.fl_str_mv 2020-07-15T20:51:25Z
dc.date.available.none.fl_str_mv 2020-07-15T20:51:25Z
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dc.type.local.none.fl_str_mv Artículo de revista
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dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.issn.none.fl_str_mv 1098-6596
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/3503
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1128/AAC.01094-17
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv https://repositorio.unbosque.edu.co
identifier_str_mv 1098-6596
instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
url http://hdl.handle.net/20.500.12495/3503
https://doi.org/10.1128/AAC.01094-17
https://repositorio.unbosque.edu.co
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv Antimicrobial agents and chemotherapy, 1098-6596, Vol. 61, Nro. 8, 2017
dc.relation.uri.none.fl_str_mv https://aac.asm.org/content/61/8/e01094-17
dc.rights.local.spa.fl_str_mv Acceso abierto
dc.rights.accessrights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
Acceso abierto
dc.rights.creativecommons.none.fl_str_mv 2017-06-05
rights_invalid_str_mv Acceso abierto
http://purl.org/coar/access_right/c_abf2
2017-06-05
eu_rights_str_mv openAccess
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv American Society for Microbiology
dc.publisher.journal.spa.fl_str_mv Antimicrobial agents and chemotherapy
institution Universidad El Bosque
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spelling Tamma , PranitaVillegas, María VirginiaVillegas, María Virginia [0000-0003-1898-9067]2020-07-15T20:51:25Z2020-07-15T20:51:25Z20171098-6596http://hdl.handle.net/20.500.12495/3503https://doi.org/10.1128/AAC.01094-17instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquehttps://repositorio.unbosque.edu.coapplication/pdfengAmerican Society for MicrobiologyAntimicrobial agents and chemotherapyAntimicrobial agents and chemotherapy, 1098-6596, Vol. 61, Nro. 8, 2017https://aac.asm.org/content/61/8/e01094-17Use of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient populationUse of β-lactam/β-lactamase inhibitors for extended-spectrum-β-lactamase infections: defining the right patient populationArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85Beta-LactamasInhibidores de beta-LactamasasCarbapenémicosESBLsBloodstream infectionNeutropeniaβ-Lactam/β-lactamase inhibitors (BLBLIs) were compared to carbapenems in two cohorts of hematological neutropenic patients with extended-spectrum-β-lactamase (ESBL) bloodstream infection (BSI): the empirical therapy cohort (174 patients) and the definitive therapy cohort (251 patients). The 30-day case fatality rates and other secondary outcomes were similar in the two therapy groups of the two cohorts and also in the propensity-matched cohorts. BLBLIs might be carbapenem-sparing alternatives for the treatment of BSI due to ESBLs in these patients.Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abierto2017-06-05LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/23e0f743-cdf2-4169-9426-cdfc044d45d9/download8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALPranita D. Tamma, Maria Virginia Villegas_2020.pdfPranita D. Tamma, Maria Virginia Villegas_2020.pdfapplication/pdf145876https://repositorio.unbosque.edu.co/bitstreams/6c17f14c-8e1c-432a-814e-b079bb5bc94c/download1231b508ea755e848c3ee9e639e508edMD51THUMBNAILPranita D. Tamma, Maria Virginia Villegas_2020.pdf.jpgPranita D. 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