Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)

La creciente demanda de alternativas a los hidrogeles sintéticos y la inconveniente proliferación de la Eichhornia crassipes que causa afectaciones al medio ambiente, parecen ser dos problemáticas que se pueden solventar entre sí. Este estudio pretendía evaluar la viabilidad de esta planta invasora...

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Autores:: Briceño Barón, Andrea Nicole
Molina Rodríguez, Angelly Nicole
Quiñones Martinez, Maria Jose

Tipo de recurso:: https://purl.org/coar/resource_type/c_7a1f

Fecha de publicación:: 2024

Institución:: Universidad El Bosque

Repositorio:: Repositorio U. El Bosque

Idioma:: spa

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repository_id_str
dc.title.none.fl_str_mv	Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)
dc.title.translated.none.fl_str_mv	Design and characterization of hydrogels using Eichhornia crassipes (water hyacinth)
title	Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)
spellingShingle	Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua) Hidrogel físico Celulosa Eichhornia crassipes Uso tópico Biomasa Material lignocelulósico 615.19 Physical hydrogel Cellulose Eichhornia crassipes Topical use Biomass Lignocellulosic material
title_short	Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)
title_full	Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)
title_fullStr	Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)
title_full_unstemmed	Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)
title_sort	Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)
dc.creator.fl_str_mv	Briceño Barón, Andrea Nicole Molina Rodríguez, Angelly Nicole Quiñones Martinez, Maria Jose
dc.contributor.advisor.none.fl_str_mv	Jiménez Cruz, Ronald Andrés Millán Cortés, Diana Milena
dc.contributor.author.none.fl_str_mv	Briceño Barón, Andrea Nicole Molina Rodríguez, Angelly Nicole Quiñones Martinez, Maria Jose
dc.subject.none.fl_str_mv	Hidrogel físico Celulosa Eichhornia crassipes Uso tópico Biomasa Material lignocelulósico
topic	Hidrogel físico Celulosa Eichhornia crassipes Uso tópico Biomasa Material lignocelulósico 615.19 Physical hydrogel Cellulose Eichhornia crassipes Topical use Biomass Lignocellulosic material
dc.subject.ddc.none.fl_str_mv	615.19
dc.subject.keywords.none.fl_str_mv	Physical hydrogel Cellulose Eichhornia crassipes Topical use Biomass Lignocellulosic material
description	La creciente demanda de alternativas a los hidrogeles sintéticos y la inconveniente proliferación de la Eichhornia crassipes que causa afectaciones al medio ambiente, parecen ser dos problemáticas que se pueden solventar entre sí. Este estudio pretendía evaluar la viabilidad de esta planta invasora como fuente de celulosa para la fabricación de hidrogeles físicos de uso tópico. Para ello, se obtuvieron cuatro prototipos mediante variaciones de la metodología Organosolv, los cuales fueron caracterizados farmacotécnicamente y reológicamente. Los ensayos revelaron que cada prototipo obtenido se trataba de un hidrogel, con un contenido de agua superior al 92%, determinado por pérdida por secado, y un rendimiento del 31.1% ± 4.9%. La esparcibilidad señaló el prototipo B como semifluido, mientras que las pruebas reológicas determinaron que entre los prototipos no hay diferencias significativas y son pseudoplásticos garantizando el uso como hidrogeles tópicos. Además, todos los hidrogeles demostraron una baja citotoxicidad. Un análisis IR sugirió diferencias estructurales en cada uno de los hidrogeles, confirmando a su vez la prevalencia de celulosa. Se llevó a cabo un análisis de varianza (p < 0.05) para determinar cambios significativos. En conjunto, estos hallazgos sugieren que la Eichhornia crassipes es una fuente viable para la fabricación de hidrogeles.
publishDate	2024
dc.date.accessioned.none.fl_str_mv	2024-05-15T18:34:49Z
dc.date.available.none.fl_str_mv	2024-05-15T18:34:49Z
dc.date.issued.none.fl_str_mv	2024-05
dc.type.coar.fl_str_mv	http://purl.org/coar/resource_type/c_7a1f
dc.type.local.none.fl_str_mv	Tesis/Trabajo de grado - Monografía - Pregrado
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dc.identifier.instname.spa.fl_str_mv	Universidad El Bosque
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identifier_str_mv	Universidad El Bosque reponame:Repositorio Institucional Universidad El Bosque repourl:https://repositorio.unbosque.edu.co
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Gels 2022, 8(3), 167. Mezger, T. Applied Rheology. 1st ed. Austria, 2015. Yuxuan, M.; Peng, L.; Jiewei, Y.; Yanjie, B.; Huan, Z.; Xiao, L.; Huilin, Y.; Lei, Y. Starch-based adhesive hydrogel with gel-point viscoelastic behavior and its application in wound sealing and hemostasis. J. Mater. Sci. Technol. 2021, 63, 228-235. Martinez, M.; García, V.; Gude, M.R. Gel point determination of thermoset prepreg by means of rheology. Polymer Testing, 2019, 78. Ho, T.C.; Chang, C. C.; Chan, H. P.; Chung, T. W.; Shu, C. W.; Chuang, K. P.; Duh, T. H.; Yang, M. H.; Tyan, Y. C. Hydrogels: Properties and Applications in Biomedicine. Molecules 2022, 27(9), 2902. Poole, C. F. Solvent selection for liquid-phase extraction. Liquid-phase extraction 2020, 45-89. Nair, L. G.; Agrawal, K.; Verma, P. Organosolv pretreatment: an in-depth purview of mechanics of the system. Bioresources and Bioprocessing 2023, 10(1), 50. Vaidya, A.A.; Murton, K.D.; Smith, D.A.; Deudal, G. A review on organosolv pretreatment of softwood with a focus on enzymatic hydrolysis of cellulose. Biomass Conv. Bioref 2022, 12, 5427–5442. Karlsson, R.M.; Larsson, P.T.; Pettersson, T.; Wågberg, L. Swelling of Cellulose-Based Fibrillar and Polymeric Networks Driven by Ion-Induced Osmotic Pressure. Langmuir, 2020. Mahajan, N.M.; Wanaskar, K.; Ali, N.; Mahapatra, D.K.; Iqbal, M.; Bhat, A.R.; Kaleem, M. Innovative Wound Healing Hydrogel Containing Chicken Feather Keratin and Soy Isoflavone Genistein: In Vivo Studies. Gels 2023, 9, 462. Wahib, S. A., Da'na, D. A.; Al-Ghouti, M. A. Insight into the extraction and characterization of cellulose nanocrystals from date pits. Arab. J. Chem., 2022, 15(3), 103650. Ferro, M.; Mannu, A.; Panzeri, W.; Theeuwen, C.H.J.; Mele A. An Integrated Approach to Optimizing Cellulose Mercerization. Polymers (Basel) 2020; 12(7):1559. Tatsumi, D.; Kanda, A.; Kondo, T. Characterization of mercerized cellulose nanofibrils prepared by aqueous counter collision process. J Wood Sci 2022, 68, 13. Väisänen, S., Kosonen, H., Ristolainen, M. et al. Cellulose dissolution in aqueous NaOH–ZnO: effect of pulp pretreatment at macro and molecular levels. Cellulose 2021, 28, 4385–4396. Duceac, I.; Tanasa, F.; Coseri, S. Selective Oxidation of Cellulose-A Multitask Platform with Significant Environmental Impact. Materials (Basel) 2022, 15(14):5076. Chrysanta, A.; Agnes, M.; Supriyanto; Andriati, N. Effect of Sodium Hydroxide and Sodium Hypochlorite on the Physicochemical Characteristics of Jack Bean Skin (Canavalia ensiformis). Pakistan Journal of Nutrition 2019, 18: 193-200. Fischer, K. Obtención de un álcali-celulosa apropiado para reacciones de derivatización. Google Patents, 2018. Fechter, C., Fischer, S., Reimann, F. et al. Influence of pulp characteristics on the properties of alkali cellulose. Cellulose 2020, 27, 7227–7241. Ali, F.; Milad, S.; Alireza, O.; Hamid, S.; Mehran, N. Synthesis of a nanocomposite with holocellulose extracted from barley straw and montmorillonite, and optimization of the removal of methylene blue dye using the synthesized adsorbent. Appl. Water Sci. 2023, 13, 243. Wang, T.; Zhao, Y. Optimization of bleaching process for cellulose extraction from apple and kale pomace and evaluation of their potentials as film forming materials. Carbohydr. Polym.,2021, 253, 117225. Jiya, V.P.; Athira, H.M.; Hafeela, S.G.; Sabu, T.; Pereira, M. Hydrogels: An overview of the history, classification, principles, applications, and kinetics, Sustain. Hydrogels, 2023, 1-22. Tudoroiu, E.; Albu, M.G.; Titorencu, I; et al. Design and evaluation of new wound dressings based on collagen-cellulose derivatives. Mater Des. 2023, 236, 112469. Supachok, T.; Sirilak, M.; Chotirot, K.; Woraporn, K.; Kasidit T.; Chutidech, T.; Anyaporn, B. 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Ethanol affects fibroblast behavior differentially at low and high doses: A comprehensive, dose-response evaluation. Toxicology reports 2021, 8, 1054–1066. Salazar, S.; Torres, C.; Rojas, J. Cytotoxic evaluation of sodium hypochlorite, using Pisum sativum L as effective bioindicator. Ecotoxicology and Environmental Safety 2019, 173, 71–76. Umai, R.; Samuel J.; Vinod K. Deep Eutectic Solvent Pretreatment of Water Hyacinth for Improved Holocellulosic Saccharification and Fermentative Co-Production of Xylitol and Lipids Using Rhodosporidium toruloides NCIM 3547, Fermentation 2022, 8(11), 591. Pintor, L.; Rivera, J.; Ngangyo, M.; Rutiaga, J. Evaluation of the chemical components of Eichhornia crassipes as an alternative raw material for pulp and paper, BioRes, 2018. 13(2), 2800-2813. Suh, E.; Park, B.; Han, B. In vitro micropropagation of water hyacinth (Eichhornia crassipes). Journal of Plant Biotechnology, 2010, 37(4), 505-510. Ahmed, F;, Wodag, A.; Gelebo, G.; Gebre, B. Ethiopian Water Hyacinth Leaf Extract as a Potential Tannery Effluent Treatment Material. Journal of Engineering, 2022. Kablanbekov, A.; Svetlana Y.; Feruza B.; Serik S.; Sergey Y.; Nurgali S.; Baimakhan S.; Alma T.; Abdurassul Z. Rice Husk Cellulose-Based Adsorbent to Extract Rare Metals: Preparing and Properties. Materials 2023, 16(18), 6277. Urbano, C. Validación del método analítico para la cuantificación de polifenoles totales en productos elaborado con té verde por método colorimétrico folin ciocalteu. Pregrado, Universidad ICESI, Santiago de Cali, 2016. ACS. Infrared Spectroscopy. ACS Reagent Chemicals, 2017, 2. Casas, E.; Raquid, J.; Yaptenco, K.; Peralta, E. Optimized drying parameters of water hyacinths (Eichhornia crassipes. L). Science Diliman 2012, 24(2). Naga, V.; Maheshwari, P.; Navya, M.; Reddy, S.; Shivakumar, H.; Gowda, D.v. Calcipotriol delivery into the skin as emulgel for effective permeation. Saudi Pharmaceutical Journal. 2014, 22(6), 591–599. Stojkov, G.; Niyazov, Z.; Picchioni, F.; Bose, R. Relationship between Structure and Rheology of Hydrogels for Various Applications. Gels. 2021, 7(4), 255. Mihranyan, A.; Edsman, K.; Strømme, M. Rheological properties of cellulose hydrogels prepared from Cladophora cellulose powder. Food Hydrocolloids 2007, 21(2), 267-272.
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spelling	Jiménez Cruz, Ronald AndrésMillán Cortés, Diana MilenaBriceño Barón, Andrea NicoleMolina Rodríguez, Angelly NicoleQuiñones Martinez, Maria Jose2024-05-15T18:34:49Z2024-05-15T18:34:49Z2024-05https://hdl.handle.net/20.500.12495/12118Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coLa creciente demanda de alternativas a los hidrogeles sintéticos y la inconveniente proliferación de la Eichhornia crassipes que causa afectaciones al medio ambiente, parecen ser dos problemáticas que se pueden solventar entre sí. Este estudio pretendía evaluar la viabilidad de esta planta invasora como fuente de celulosa para la fabricación de hidrogeles físicos de uso tópico. Para ello, se obtuvieron cuatro prototipos mediante variaciones de la metodología Organosolv, los cuales fueron caracterizados farmacotécnicamente y reológicamente. Los ensayos revelaron que cada prototipo obtenido se trataba de un hidrogel, con un contenido de agua superior al 92%, determinado por pérdida por secado, y un rendimiento del 31.1% ± 4.9%. La esparcibilidad señaló el prototipo B como semifluido, mientras que las pruebas reológicas determinaron que entre los prototipos no hay diferencias significativas y son pseudoplásticos garantizando el uso como hidrogeles tópicos. Además, todos los hidrogeles demostraron una baja citotoxicidad. Un análisis IR sugirió diferencias estructurales en cada uno de los hidrogeles, confirmando a su vez la prevalencia de celulosa. Se llevó a cabo un análisis de varianza (p < 0.05) para determinar cambios significativos. En conjunto, estos hallazgos sugieren que la Eichhornia crassipes es una fuente viable para la fabricación de hidrogeles.PregradoQuímico FarmacéuticoThe increasing demand for alternatives to synthetic hydrogels and the issue of Eichhornia crassipes' proliferation, which causes environmental damage, seem to be two problems that can be addressed by each other. This study aimed to evaluate the feasibility of utilizing this invasive plant as a source of cellulose for the fabrication of topical-use physical hydrogels. Four prototypes were synthesized via variations of the Organosolv methodology and subsequently subjected to pharmaceutical characterization. The experimental assays demonstrated that each prototype constituted a hydrogel, characterized by a water content exceeding 92%, as determined through drying loss, with a yield of 31.1% ± 4.9%. Evaluation of spreadability indicated the suitability of prototype B, while rheological assessments determined that there were no significant differences among the prototypes and they were all pseudoplastic, enserió their use as topical hydrogels. Furthermore, all hydrogels exhibited low cytotoxicity. Infrared spectroscopy revealed distinctive structural variances among the hydrogel formulations, confirming the predominance of cellulose. Statistical analysis, conducted via analysis of variance (p < 0.05), underscored significant differences. Collectively, these findings display the potential of Eichhornia crassipes as a viable cellulose source for hydrogel production.application/pdfAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Acceso abiertoinfo:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Hidrogel físicoCelulosaEichhornia crassipesUso tópicoBiomasaMaterial lignocelulósico615.19Physical hydrogelCelluloseEichhornia crassipesTopical useBiomassLignocellulosic materialDiseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)Design and characterization of hydrogels using Eichhornia crassipes (water hyacinth)Química FarmacéuticaUniversidad El BosqueFacultad de CienciasTesis/Trabajo de grado - Monografía - Pregradohttps://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesishttps://purl.org/coar/version/c_ab4af688f83e57aaLaffleur, F.; Keckeis, V. 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Food Hydrocolloids 2007, 21(2), 267-272.spaORIGINALTrabajo de grado.pdfTrabajo de grado.pdfapplication/pdf14646016https://repositorio.unbosque.edu.co/bitstreams/2e77d939-cfb1-4873-8d4b-4566d12b20a5/download5b295fa5c4d2af0ab260d210311263a6MD53Anexo 2 Material suplementario.pdfAnexo 2 Material suplementario.pdfapplication/pdf480351https://repositorio.unbosque.edu.co/bitstreams/65d04924-5aa5-4664-aebe-10a45dc8afd6/downloadbd15114175e967ec7bb50dd5a5b40817MD59Anexo 3 Certificado de identificación taxonómica.pdfAnexo 3 Certificado de identificación taxonómica.pdfapplication/pdf342143https://repositorio.unbosque.edu.co/bitstreams/57f188e8-b09d-42b6-8214-ceaf2ec2c321/downloadd9e6a3d774f6171294734de48561a0e7MD58LICENSElicense.txtlicense.txttext/plain; charset=utf-82000https://repositorio.unbosque.edu.co/bitstreams/7d184450-b4df-4c0b-bc70-0458f4266486/download17cc15b951e7cc6b3728a574117320f9MD55Anexo 1 Acta de aprobacion.pdfapplication/pdf1752988https://repositorio.unbosque.edu.co/bitstreams/27243f21-2979-417c-8356-5ed159e3e4a1/download75303d62896c9c26307030be83464986MD520Carta de autorizacion.pdfapplication/pdf454357https://repositorio.unbosque.edu.co/bitstreams/0b1aa565-af6e-43bc-956a-9ed0dc3787d7/download3272b1a80fff83571f33ed27d9be9488MD521CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; 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Diseño y caracterización de hidrogeles empleando Eichhornia crassipes (buchón de agua)

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