Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report
Background Extranodal NK/T-cell nasal type lymphoma, is an uncommon subtype of non-Hodgkin’s lymphoma. It is mostly located in the nasal cavity, but in some cases can be found outside of it. The central nervous system (CNS) is a rare site of primary or progression of this lymphoma. Only one similar...
- Autores:
-
Rodríguez-Hernández, Pablo Andrés
Gil-Duran, Melissa
Riveros-Loaiza, Laura María
Miranda-Acosta, Yeiris
Romero-Rojas, Alfredo Ernesto
Torres-Bayona, Sergio
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2021
- Institución:
- Universidad El Bosque
- Repositorio:
- Repositorio U. El Bosque
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.unbosque.edu.co:20.500.12495/5901
- Palabra clave:
- Extranodal nasal type NK-T-Cell Lymphoma
Peripheral Nervous System
Cauda Equina Sydrome
- Rights
- openAccess
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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|
dc.title.spa.fl_str_mv |
Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report |
dc.title.translated.spa.fl_str_mv |
Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report |
title |
Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report |
spellingShingle |
Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report Extranodal nasal type NK-T-Cell Lymphoma Peripheral Nervous System Cauda Equina Sydrome |
title_short |
Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report |
title_full |
Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report |
title_fullStr |
Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report |
title_full_unstemmed |
Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report |
title_sort |
Atypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case report |
dc.creator.fl_str_mv |
Rodríguez-Hernández, Pablo Andrés Gil-Duran, Melissa Riveros-Loaiza, Laura María Miranda-Acosta, Yeiris Romero-Rojas, Alfredo Ernesto Torres-Bayona, Sergio |
dc.contributor.author.none.fl_str_mv |
Rodríguez-Hernández, Pablo Andrés Gil-Duran, Melissa Riveros-Loaiza, Laura María Miranda-Acosta, Yeiris Romero-Rojas, Alfredo Ernesto Torres-Bayona, Sergio |
dc.subject.keywords.spa.fl_str_mv |
Extranodal nasal type NK-T-Cell Lymphoma Peripheral Nervous System Cauda Equina Sydrome |
topic |
Extranodal nasal type NK-T-Cell Lymphoma Peripheral Nervous System Cauda Equina Sydrome |
description |
Background Extranodal NK/T-cell nasal type lymphoma, is an uncommon subtype of non-Hodgkin’s lymphoma. It is mostly located in the nasal cavity, but in some cases can be found outside of it. The central nervous system (CNS) is a rare site of primary or progression of this lymphoma. Only one similar case of cauda equina syndrome had been reported previously in a postmortem patient. Patients with this type of lymphoma have a poor prognosis and some authors have described a median overall survival of 8.5 months from diagnosis (range 3.8–24 months from CNS involvement). Case report We report a case of a 38-year-old female with diagnosis of extranodal NK/T-cell nasal lymphoma. After radiotherapy and chemotherapy, she was admitted to the emergency room presenting neurologic impairment in the limbs (2/5 in MRC grading scale). Brain neuroimaging did not show any abnormality and lumbar puncture was not possible despite multiple attempts. Thoracolumbar imaging showed an involvement of the cauda equina and intraoperative findings revealed thickening and swelling of the nerve roots confirming an infiltration by lymphoma in the pathology. To date, our patient has an overall survival of 18 months from diagnosis of lymphoma and 7 months from peripheral nervous system involvement (actually 5/5 in MRC grading scale). Conclusions In this particular case, the surgery goal was to obtain a diagnosis to guide treatment but not to relieve symptoms. We considered its diffusion and knowledge as imperative for all practitioners involved in the care of this patient. |
publishDate |
2021 |
dc.date.accessioned.none.fl_str_mv |
2021-06-23T21:09:10Z |
dc.date.available.none.fl_str_mv |
2021-06-23T21:09:10Z |
dc.date.issued.none.fl_str_mv |
2021-09 |
dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
dc.type.local.none.fl_str_mv |
Artículo de revista |
dc.type.coar.none.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/article |
format |
http://purl.org/coar/resource_type/c_6501 |
dc.identifier.issn.none.fl_str_mv |
2214-7519 |
dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/20.500.12495/5901 |
dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1016/j.inat.2021.101213 |
dc.identifier.instname.spa.fl_str_mv |
instname:Universidad El Bosque |
dc.identifier.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional Universidad El Bosque |
dc.identifier.repourl.none.fl_str_mv |
repourl:https://repositorio.unbosque.edu.co |
identifier_str_mv |
2214-7519 instname:Universidad El Bosque reponame:Repositorio Institucional Universidad El Bosque repourl:https://repositorio.unbosque.edu.co |
url |
http://hdl.handle.net/20.500.12495/5901 https://doi.org/10.1016/j.inat.2021.101213 |
dc.language.iso.none.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartofseries.spa.fl_str_mv |
Interdisciplinary Neurosurgery, 2214-7519, Vol. 25, 2021 |
dc.relation.uri.none.fl_str_mv |
https://www.sciencedirect.com/science/article/pii/S2214751921001250 |
dc.rights.*.fl_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
dc.rights.uri.*.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.rights.local.spa.fl_str_mv |
Acceso abierto |
dc.rights.accessrights.none.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess Acceso abierto |
rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ Acceso abierto http://purl.org/coar/access_right/c_abf2 |
eu_rights_str_mv |
openAccess |
dc.format.mimetype.none.fl_str_mv |
application/pdf |
dc.publisher.spa.fl_str_mv |
Elsevier |
dc.publisher.journal.spa.fl_str_mv |
Interdisciplinary Neurosurgery |
institution |
Universidad El Bosque |
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Rodríguez-Hernández, Pablo AndrésGil-Duran, MelissaRiveros-Loaiza, Laura MaríaMiranda-Acosta, YeirisRomero-Rojas, Alfredo ErnestoTorres-Bayona, Sergio2021-06-23T21:09:10Z2021-06-23T21:09:10Z2021-092214-7519http://hdl.handle.net/20.500.12495/5901https://doi.org/10.1016/j.inat.2021.101213instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coapplication/pdfengElsevierInterdisciplinary NeurosurgeryInterdisciplinary Neurosurgery, 2214-7519, Vol. 25, 2021https://www.sciencedirect.com/science/article/pii/S2214751921001250Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abiertoAtypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case reportAtypical cauda equina presentation of an extranodal nasal type NK/T cell lymphoma: a case reportArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85Extranodal nasal type NK-T-Cell LymphomaPeripheral Nervous SystemCauda Equina SydromeBackground Extranodal NK/T-cell nasal type lymphoma, is an uncommon subtype of non-Hodgkin’s lymphoma. It is mostly located in the nasal cavity, but in some cases can be found outside of it. The central nervous system (CNS) is a rare site of primary or progression of this lymphoma. Only one similar case of cauda equina syndrome had been reported previously in a postmortem patient. Patients with this type of lymphoma have a poor prognosis and some authors have described a median overall survival of 8.5 months from diagnosis (range 3.8–24 months from CNS involvement). Case report We report a case of a 38-year-old female with diagnosis of extranodal NK/T-cell nasal lymphoma. After radiotherapy and chemotherapy, she was admitted to the emergency room presenting neurologic impairment in the limbs (2/5 in MRC grading scale). Brain neuroimaging did not show any abnormality and lumbar puncture was not possible despite multiple attempts. Thoracolumbar imaging showed an involvement of the cauda equina and intraoperative findings revealed thickening and swelling of the nerve roots confirming an infiltration by lymphoma in the pathology. To date, our patient has an overall survival of 18 months from diagnosis of lymphoma and 7 months from peripheral nervous system involvement (actually 5/5 in MRC grading scale). Conclusions In this particular case, the surgery goal was to obtain a diagnosis to guide treatment but not to relieve symptoms. We considered its diffusion and knowledge as imperative for all practitioners involved in the care of this patient.CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://repositorio.unbosque.edu.co/bitstreams/144648be-fb6d-4569-a9f7-dcb656f3aeef/download4460e5956bc1d1639be9ae6146a50347MD52ORIGINALRodríguez_Hernández_Pablo_Andrés_2021.pdfRodríguez_Hernández_Pablo_Andrés_2021.pdfapplication/pdf6038596https://repositorio.unbosque.edu.co/bitstreams/4446a1c5-abe6-418b-ac15-ecf05cf1175f/download45445ade522c8ae5bbcc2bc8a82ee8a3MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/d431ce3f-d1f8-4ab6-a7ab-881aef3aa376/download8a4605be74aa9ea9d79846c1fba20a33MD53THUMBNAILRodríguez_Hernández_Pablo_Andrés_2021.pdf.jpgRodríguez_Hernández_Pablo_Andrés_2021.pdf.jpgIM Thumbnailimage/jpeg10202https://repositorio.unbosque.edu.co/bitstreams/3a482c92-660c-4a22-8255-4f5e3883e96d/downloada63fa7956a0c9feaa65cc0240dbe6ff3MD54TEXTRodríguez_Hernández_Pablo_Andrés_2021.pdf.txtRodríguez_Hernández_Pablo_Andrés_2021.pdf.txtExtracted texttext/plain21988https://repositorio.unbosque.edu.co/bitstreams/ee72eb0c-0993-45c0-b3ab-f307d4f3cbf3/download4148b998c5f7ebc1e2fdd2233a8c6556MD5520.500.12495/5901oai:repositorio.unbosque.edu.co:20.500.12495/59012024-02-07 06:31:18.379http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internacionalopen.accesshttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.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 |