SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude

Background: Given the high prevalence of chronic obstructive pulmonary disease (COPD) in Bogota (2630 m above the sea), screening methods are required for COPD patients who develop exercise-induced hypoxemia (EIH). Objective: The objective was to measure the productive capacity of basal oxygen satur...

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Autores:
Colmenares, Rafael Acero
Lombo, Carlos
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/2404
Acceso en línea:
http://hdl.handle.net/20.500.12495/2404
https://doi.org/10.2147/COPD.S207467
Palabra clave:
Oximetría
Tamizaje masivo
Enfermedades pulmonares
COPD
Altitude
walk test
Rights
License
Attribution-NonCommercial 4.0 International
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dc.title.spa.fl_str_mv SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
dc.title.translated.none.fl_str_mv SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
title SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
spellingShingle SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
Oximetría
Tamizaje masivo
Enfermedades pulmonares
COPD
Altitude
walk test
title_short SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
title_full SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
title_fullStr SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
title_full_unstemmed SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
title_sort SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitude
dc.creator.fl_str_mv Colmenares, Rafael Acero
Lombo, Carlos
dc.contributor.author.none.fl_str_mv Colmenares, Rafael Acero
Lombo, Carlos
dc.subject.decs.spa.fl_str_mv Oximetría
Tamizaje masivo
Enfermedades pulmonares
topic Oximetría
Tamizaje masivo
Enfermedades pulmonares
COPD
Altitude
walk test
dc.subject.keywords.spa.fl_str_mv COPD
Altitude
walk test
description Background: Given the high prevalence of chronic obstructive pulmonary disease (COPD) in Bogota (2630 m above the sea), screening methods are required for COPD patients who develop exercise-induced hypoxemia (EIH). Objective: The objective was to measure the productive capacity of basal oxygen saturation for the detection of EIH during the 6-min walking test (6MWT) in patients diagnosed with COPD in a hospital in Bogotá. Design: This was a cross-sectional, retrospective study. Population: Patients diagnosed with COPD with SaO2≥88% who attended the Pneumology Section of the FSFB for a 6MWT between 2013 and 2017 were included in the study. Measurements: Age, sex, anthropometric data, SaO2, SaO2 during 6MWT, and spirometry were evaluated. Results: Ninety-two patients with EIH and 32 patients without EIH were studied. Statistically significant differences were found in SaO2, minimum SaO2 during 6MWT, and BMI (90.8% vs 93%, 80.3% vs 88.9%, and 26.7 kg/m2 vs 23.8 kg/m2, respectively). FEV1 was without statistically significant differences (74.1% vs 78.6%). The ROC curve showed a better cut-off point for detecting EIH with basal SaO2≤92% (sensitivity 76.1%, specificity 62.5%, NPV 47.6%, and PPV 85.4%) and SaO2≤94% as the best sensitivity point (sensitivity 94.6%, specificity 15.6%, NPV 76.3%, and PPV 50%). Conclusion: SaO2 is not a good screening test for EIH in COPD patients at moderate altitude.
publishDate 2019
dc.date.issued.none.fl_str_mv 2019
dc.date.accessioned.none.fl_str_mv 2020-04-26T21:29:10Z
dc.date.available.none.fl_str_mv 2020-04-26T21:29:10Z
dc.type.spa.fl_str_mv article
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dc.type.local.spa.fl_str_mv artículo
dc.identifier.issn.none.fl_str_mv 1178-2005
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/2404
dc.identifier.doi.none.fl_str_mv https://doi.org/10.2147/COPD.S207467
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
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instname:Universidad El Bosque
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url http://hdl.handle.net/20.500.12495/2404
https://doi.org/10.2147/COPD.S207467
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv International Journal of COPD, 1178-2005, Vol. 2019, Nro. 14, 2019, p. 1951-1958
dc.relation.uri.none.fl_str_mv https://www.dovepress.com/sao2-as-a-predictor-of-exercise-induced-hypoxemia-in-chronic-obstructi-peer-reviewed-article-COPD
dc.rights.*.fl_str_mv Attribution-NonCommercial 4.0 International
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dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.local.spa.fl_str_mv Acceso abierto
dc.rights.accessrights.none.fl_str_mv http://purl.org/coar/access_right/c_abf98
dc.rights.creativecommons.none.fl_str_mv 2019
rights_invalid_str_mv Attribution-NonCommercial 4.0 International
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dc.publisher.spa.fl_str_mv Dove Medical Press
dc.publisher.journal.spa.fl_str_mv International Journal of COPD
institution Universidad El Bosque
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spelling Colmenares, Rafael AceroLombo, Carlos2020-04-26T21:29:10Z2020-04-26T21:29:10Z20191178-2005http://hdl.handle.net/20.500.12495/2404https://doi.org/10.2147/COPD.S207467instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coapplication/pdfengDove Medical PressInternational Journal of COPDInternational Journal of COPD, 1178-2005, Vol. 2019, Nro. 14, 2019, p. 1951-1958https://www.dovepress.com/sao2-as-a-predictor-of-exercise-induced-hypoxemia-in-chronic-obstructi-peer-reviewed-article-COPDAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/Acceso abiertohttp://purl.org/coar/access_right/c_abf982019http://purl.org/coar/access_right/c_abf2SaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitudeSaO2 as a predictor of exercise-induced hypoxemia in chronic obstructive pulmonary disease at moderate altitudearticleartículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501OximetríaTamizaje masivoEnfermedades pulmonaresCOPDAltitudewalk testBackground: Given the high prevalence of chronic obstructive pulmonary disease (COPD) in Bogota (2630 m above the sea), screening methods are required for COPD patients who develop exercise-induced hypoxemia (EIH). Objective: The objective was to measure the productive capacity of basal oxygen saturation for the detection of EIH during the 6-min walking test (6MWT) in patients diagnosed with COPD in a hospital in Bogotá. Design: This was a cross-sectional, retrospective study. Population: Patients diagnosed with COPD with SaO2≥88% who attended the Pneumology Section of the FSFB for a 6MWT between 2013 and 2017 were included in the study. Measurements: Age, sex, anthropometric data, SaO2, SaO2 during 6MWT, and spirometry were evaluated. Results: Ninety-two patients with EIH and 32 patients without EIH were studied. Statistically significant differences were found in SaO2, minimum SaO2 during 6MWT, and BMI (90.8% vs 93%, 80.3% vs 88.9%, and 26.7 kg/m2 vs 23.8 kg/m2, respectively). FEV1 was without statistically significant differences (74.1% vs 78.6%). The ROC curve showed a better cut-off point for detecting EIH with basal SaO2≤92% (sensitivity 76.1%, specificity 62.5%, NPV 47.6%, and PPV 85.4%) and SaO2≤94% as the best sensitivity point (sensitivity 94.6%, specificity 15.6%, NPV 76.3%, and PPV 50%). 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