Latin American consensus: children born small for gestational age

Background Children born small for gestational age (SGA) experience higher rates of morbidity and mortality than those born appropriate for gestational age. In Latin America, identification and optimal management of children born SGA is a critical issue. Leading experts in pediatric endocrinology th...

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Autores:
Boguszewski, Margaret CS
Bergada, Ignacio
Gunczler, Peter
Ortiz, Teresa
Llano, Mauricio
Domené, Horacio M.
Calzada-León, Raúl
Blanco, Armando
Barrientos, Margarita
Lanes, Roberto
Jaramillo, Orlando
Mericq, Verónica
Damiani, Durval
Belgorosky, Alicia
Procel, Patricio
Tipo de recurso:
Fecha de publicación:
2015
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/1573
Acceso en línea:
http://hdl.handle.net/20.500.12495/1573
https://doi.org/10.1186/1471-2431-11-66
Palabra clave:
Hormona del crecimiento
Edad gestacional
Endocrinología
Pediatría
Growth hormone
Growth hormone treatment
Growth hormone therapy
Acanthosis nigricans
Rights
License
Attribution 4.0 International
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dc.title.spa.fl_str_mv Latin American consensus: children born small for gestational age
title Latin American consensus: children born small for gestational age
spellingShingle Latin American consensus: children born small for gestational age
Hormona del crecimiento
Edad gestacional
Endocrinología
Pediatría
Growth hormone
Growth hormone treatment
Growth hormone therapy
Acanthosis nigricans
title_short Latin American consensus: children born small for gestational age
title_full Latin American consensus: children born small for gestational age
title_fullStr Latin American consensus: children born small for gestational age
title_full_unstemmed Latin American consensus: children born small for gestational age
title_sort Latin American consensus: children born small for gestational age
dc.creator.fl_str_mv Boguszewski, Margaret CS
Bergada, Ignacio
Gunczler, Peter
Ortiz, Teresa
Llano, Mauricio
Domené, Horacio M.
Calzada-León, Raúl
Blanco, Armando
Barrientos, Margarita
Lanes, Roberto
Jaramillo, Orlando
Mericq, Verónica
Damiani, Durval
Belgorosky, Alicia
Procel, Patricio
dc.contributor.author.none.fl_str_mv Boguszewski, Margaret CS
Bergada, Ignacio
Gunczler, Peter
Ortiz, Teresa
Llano, Mauricio
Domené, Horacio M.
Calzada-León, Raúl
Blanco, Armando
Barrientos, Margarita
Lanes, Roberto
Jaramillo, Orlando
Mericq, Verónica
Damiani, Durval
Belgorosky, Alicia
Procel, Patricio
dc.subject.decs.spa.fl_str_mv Hormona del crecimiento
Edad gestacional
Endocrinología
Pediatría
topic Hormona del crecimiento
Edad gestacional
Endocrinología
Pediatría
Growth hormone
Growth hormone treatment
Growth hormone therapy
Acanthosis nigricans
dc.subject.keywords.spa.fl_str_mv Growth hormone
Growth hormone treatment
Growth hormone therapy
Acanthosis nigricans
description Background Children born small for gestational age (SGA) experience higher rates of morbidity and mortality than those born appropriate for gestational age. In Latin America, identification and optimal management of children born SGA is a critical issue. Leading experts in pediatric endocrinology throughout Latin America established working groups in order to discuss key challenges regarding the evaluation and management of children born SGA and ultimately develop a consensus statement. Discussion SGA is defined as a birth weight and/or birth length greater than 2 standard deviations (SD) below the population reference mean for gestational age. SGA refers to body size and implies length-weight reference data in a geographical population whose ethnicity is known and specific to this group. Ideally, each country/region within Latin America should establish its own standards and make relevant updates. SGA children should be evaluated with standardized measures by trained personnel every 3 months during year 1 and every 6 months during year 2. Those without catch-up growth within the first 6 months of life need further evaluation, as do children whose weight is ≤ -2 SD at age 2 years. Growth hormone treatment can begin in SGA children > 2 years with short stature (< -2.0 SD) and a growth velocity < 25th percentile for their age, and should continue until final height (a growth velocity below 2 cm/year or a bone age of > 14 years for girls and > 16 years for boys) is reached. Blood glucose, thyroid function, HbA1c, and insulin-like growth factor-1 (IGF-1) should be monitored once a year. Monitoring insulin changes from baseline and surrogates of insulin sensitivity is essential. Reduced fetal growth followed by excessive postnatal catch-up in height, and particularly in weight, should be closely monitored. In both sexes, gonadal function should be monitored especially during puberty. Summary Children born SGA should be carefully followed by a multidisciplinary group that includes perinatologists, pediatricians, nutritionists, and pediatric endocrinologists since 10% to 15% will continue to have weight and height deficiency through development and may benefit from growth hormone treatment. Standards/guidelines should be developed on a country/region basis throughout Latin America.
publishDate 2015
dc.date.issued.none.fl_str_mv 2015
dc.date.accessioned.none.fl_str_mv 2019-07-29T16:43:51Z
dc.date.available.none.fl_str_mv 2019-07-29T16:43:51Z
dc.type.spa.fl_str_mv article
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dc.type.local.spa.fl_str_mv artículo
dc.identifier.issn.none.fl_str_mv 1471-2431
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/1573
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1186/1471-2431-11-66
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
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instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
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url http://hdl.handle.net/20.500.12495/1573
https://doi.org/10.1186/1471-2431-11-66
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv BMC Pediatrics, 1471-2431, Vol. 11,Nro.66 2015, p.1-10
dc.relation.uri.none.fl_str_mv https://bmcpediatr.biomedcentral.com/articles/10.1186/1471-2431-11-66
dc.rights.*.fl_str_mv Attribution 4.0 International
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dc.rights.local.spa.fl_str_mv Acceso abierto
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dc.rights.creativecommons.none.fl_str_mv 2011
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dc.publisher.spa.fl_str_mv Biomed Central
dc.publisher.journal.spa.fl_str_mv BMC Pediatrics
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spelling Boguszewski, Margaret CSBergada, IgnacioGunczler, PeterOrtiz, TeresaLlano, MauricioDomené, Horacio M.Calzada-León, RaúlBlanco, ArmandoBarrientos, MargaritaLanes, RobertoJaramillo, OrlandoMericq, VerónicaDamiani, DurvalBelgorosky, AliciaProcel, Patricio2019-07-29T16:43:51Z2019-07-29T16:43:51Z20151471-2431http://hdl.handle.net/20.500.12495/1573https://doi.org/10.1186/1471-2431-11-66instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coapplication/pdfengBiomed CentralBMC PediatricsBMC Pediatrics, 1471-2431, Vol. 11,Nro.66 2015, p.1-10https://bmcpediatr.biomedcentral.com/articles/10.1186/1471-2431-11-66Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Acceso abiertohttp://purl.org/coar/access_right/c_abf4582011http://purl.org/coar/access_right/c_abf2Latin American consensus: children born small for gestational agearticleartículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501Hormona del crecimientoEdad gestacionalEndocrinologíaPediatríaGrowth hormoneGrowth hormone treatmentGrowth hormone therapyAcanthosis nigricansBackground Children born small for gestational age (SGA) experience higher rates of morbidity and mortality than those born appropriate for gestational age. In Latin America, identification and optimal management of children born SGA is a critical issue. Leading experts in pediatric endocrinology throughout Latin America established working groups in order to discuss key challenges regarding the evaluation and management of children born SGA and ultimately develop a consensus statement. Discussion SGA is defined as a birth weight and/or birth length greater than 2 standard deviations (SD) below the population reference mean for gestational age. SGA refers to body size and implies length-weight reference data in a geographical population whose ethnicity is known and specific to this group. Ideally, each country/region within Latin America should establish its own standards and make relevant updates. SGA children should be evaluated with standardized measures by trained personnel every 3 months during year 1 and every 6 months during year 2. Those without catch-up growth within the first 6 months of life need further evaluation, as do children whose weight is ≤ -2 SD at age 2 years. Growth hormone treatment can begin in SGA children > 2 years with short stature (< -2.0 SD) and a growth velocity < 25th percentile for their age, and should continue until final height (a growth velocity below 2 cm/year or a bone age of > 14 years for girls and > 16 years for boys) is reached. Blood glucose, thyroid function, HbA1c, and insulin-like growth factor-1 (IGF-1) should be monitored once a year. Monitoring insulin changes from baseline and surrogates of insulin sensitivity is essential. Reduced fetal growth followed by excessive postnatal catch-up in height, and particularly in weight, should be closely monitored. In both sexes, gonadal function should be monitored especially during puberty. Summary Children born SGA should be carefully followed by a multidisciplinary group that includes perinatologists, pediatricians, nutritionists, and pediatric endocrinologists since 10% to 15% will continue to have weight and height deficiency through development and may benefit from growth hormone treatment. 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