Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa

A multicenter, retrospective study of patients infected with carbapenem-resistant Pseudomonas aeruginosa who were treated with ceftolozane/tazobactam was performed. Among 35 patients, pneumonia was the most common indication and treatment was successful in 26 (74%). Treatment failure was observed in...

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Autores:
Munita, Jose M.
Aitken, Samuel L.
Miller, William R.
Perez, Federico
Rosa, Rossana
Shimose, Luis A.
Lichtenberger, Paola N.
Abbo, Lilian M.
Jain, Rupali
Nigo, Masayuki
Wanger, Audrey
Araos, Rafael
Tran, Truc T.
Adachi, Javier
Rakita, Robert
Shelburne, Samuel
Bonomo, Robert A.
Arias, Cesar A.
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/3679
Acceso en línea:
http://hdl.handle.net/20.500.12495/3679
https://doi.org/10.1093/cid/cix014
https://repositorio.unbosque.edu.co
Palabra clave:
Ceftolozane
Carbapenem resistant
P. aeruginosa
Multidrug resistant
Rights
openAccess
License
Acceso abierto
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dc.title.spa.fl_str_mv Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa
dc.title.translated.spa.fl_str_mv Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa
title Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa
spellingShingle Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa
Ceftolozane
Carbapenem resistant
P. aeruginosa
Multidrug resistant
title_short Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa
title_full Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa
title_fullStr Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa
title_full_unstemmed Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa
title_sort Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa
dc.creator.fl_str_mv Munita, Jose M.
Aitken, Samuel L.
Miller, William R.
Perez, Federico
Rosa, Rossana
Shimose, Luis A.
Lichtenberger, Paola N.
Abbo, Lilian M.
Jain, Rupali
Nigo, Masayuki
Wanger, Audrey
Araos, Rafael
Tran, Truc T.
Adachi, Javier
Rakita, Robert
Shelburne, Samuel
Bonomo, Robert A.
Arias, Cesar A.
dc.contributor.author.none.fl_str_mv Munita, Jose M.
Aitken, Samuel L.
Miller, William R.
Perez, Federico
Rosa, Rossana
Shimose, Luis A.
Lichtenberger, Paola N.
Abbo, Lilian M.
Jain, Rupali
Nigo, Masayuki
Wanger, Audrey
Araos, Rafael
Tran, Truc T.
Adachi, Javier
Rakita, Robert
Shelburne, Samuel
Bonomo, Robert A.
Arias, Cesar A.
dc.subject.keywords.spa.fl_str_mv Ceftolozane
Carbapenem resistant
P. aeruginosa
Multidrug resistant
topic Ceftolozane
Carbapenem resistant
P. aeruginosa
Multidrug resistant
description A multicenter, retrospective study of patients infected with carbapenem-resistant Pseudomonas aeruginosa who were treated with ceftolozane/tazobactam was performed. Among 35 patients, pneumonia was the most common indication and treatment was successful in 26 (74%). Treatment failure was observed in all cases where isolates demonstrated ceftolozane-tazobactam minimum inhibitory concentrations ≥8 μg/mL.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-08-05T13:34:42Z
dc.date.available.none.fl_str_mv 2020-08-05T13:34:42Z
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dc.type.local.none.fl_str_mv Artículo de revista
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dc.identifier.issn.none.fl_str_mv 1537-6591
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/3679
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1093/cid/cix014
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
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identifier_str_mv 1537-6591
instname:Universidad El Bosque
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url http://hdl.handle.net/20.500.12495/3679
https://doi.org/10.1093/cid/cix014
https://repositorio.unbosque.edu.co
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv Clinical Infectious Diseases, 1537-6591, Vol. 65, Nro. 1, 2017, p. 158–161
dc.relation.uri.none.fl_str_mv https://academic.oup.com/cid/article/65/1/158/3069333
dc.rights.local.spa.fl_str_mv Acceso abierto
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info:eu-repo/semantics/openAccess
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dc.rights.creativecommons.none.fl_str_mv 2017-03-14
rights_invalid_str_mv Acceso abierto
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2017-03-14
eu_rights_str_mv openAccess
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dc.publisher.spa.fl_str_mv Oxford University Press
dc.publisher.journal.spa.fl_str_mv Clinical Infectious Diseases
institution Universidad El Bosque
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spelling Munita, Jose M.Aitken, Samuel L.Miller, William R.Perez, FedericoRosa, RossanaShimose, Luis A.Lichtenberger, Paola N.Abbo, Lilian M.Jain, RupaliNigo, MasayukiWanger, AudreyAraos, RafaelTran, Truc T.Adachi, JavierRakita, RobertShelburne, SamuelBonomo, Robert A.Arias, Cesar A.2020-08-05T13:34:42Z2020-08-05T13:34:42Z1537-6591http://hdl.handle.net/20.500.12495/3679https://doi.org/10.1093/cid/cix014instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquehttps://repositorio.unbosque.edu.coapplication/pdfengOxford University PressClinical Infectious DiseasesClinical Infectious Diseases, 1537-6591, Vol. 65, Nro. 1, 2017, p. 158–161https://academic.oup.com/cid/article/65/1/158/3069333Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosaMulticenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosaArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85CeftolozaneCarbapenem resistantP. aeruginosaMultidrug resistantA multicenter, retrospective study of patients infected with carbapenem-resistant Pseudomonas aeruginosa who were treated with ceftolozane/tazobactam was performed. Among 35 patients, pneumonia was the most common indication and treatment was successful in 26 (74%). Treatment failure was observed in all cases where isolates demonstrated ceftolozane-tazobactam minimum inhibitory concentrations ≥8 μg/mL.Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abierto2017-03-14ORIGINALMunita, Jose M..pdfMunita, Jose M..pdfapplication/pdf152229https://repositorio.unbosque.edu.co/bitstreams/57c151bd-7bd1-4dcb-83ba-f94e43c0fc88/downloada97c5a71060781d799d5000917ac40d7MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/958475c1-8316-415e-8482-a1b60214ade3/download8a4605be74aa9ea9d79846c1fba20a33MD52THUMBNAILMunita, Jose M. .pdf.jpgMunita, Jose M. .pdf.jpgimage/jpeg5775https://repositorio.unbosque.edu.co/bitstreams/29553d38-4ec4-4d35-bed8-68f9c26a4fa1/download7210a811635d1799e7c05fee5d259be7MD53Munita, Jose M..pdf.jpgMunita, Jose M..pdf.jpgIM Thumbnailimage/jpeg10756https://repositorio.unbosque.edu.co/bitstreams/2f439bd1-ea52-47a6-9c81-6813039a4a93/downloadbe37d4ad09313865c101050bd0c50479MD54TEXTMunita, Jose M..pdf.txtMunita, Jose M..pdf.txtExtracted texttext/plain20923https://repositorio.unbosque.edu.co/bitstreams/5d871a34-318c-462b-b064-c183f8f61058/download94980af1c8e49a6cbb5c7235f23f06bcMD5520.500.12495/3679oai:repositorio.unbosque.edu.co:20.500.12495/36792024-02-07 10:02:59.983restrictedhttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.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