MitraClipVR as bridging strategy for heart transplantation in chagas cardiomyopathy: a case report

Background Patients with end-stage heart failure, suffering from severe pulmonary hypertension (PH) and elevated pulmonary vascular resistance, are not eligible for heart transplant due to high mortality risk and primary graft dysfunction. Severe PH may be favoured by functional severe mitral regurg...

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Autores:
Vásquez-Rodriguez, Juan Felipe
Medina, Héctor Manuel
Cabrales, Jaime Ramón
Torres, Adriana Gisella
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/5812
Acceso en línea:
http://hdl.handle.net/20.500.12495/5812
https://doi.org/10.1093/ehjcr/ytz238
Palabra clave:
Case report
Heart failure
Chagasic cardiomyopathy MitraClip®
Pulmonary hypertension
Heart transplant
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
Description
Summary:Background Patients with end-stage heart failure, suffering from severe pulmonary hypertension (PH) and elevated pulmonary vascular resistance, are not eligible for heart transplant due to high mortality risk and primary graft dysfunction. Severe PH may be favoured by functional severe mitral regurgitation, which is present in many cardiopathies like end-stage Chagasic cardiomyopathy. Case summary We present a case of a young man with end-stage heart failure secondary to Chagas cardiomyopathy with severe functional mitral regurgitation (FMR) and severe PH. The patient received percutaneous correction with MitraClipVR system reducing PH and making him a suitable candidate for heart transplant. Discussion In patients with advanced heart failure, FMR, and severe PH, optimal treatment according to current guide lines is recommended. MitraClipVR therapy appears to be safe and effective for control of severe PH as a bridge measure for cardiac transplantation.