Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery

Objective To establish the association between adipokine levels and markers of periodontal involvement as risk indicators of early stages of RA (eRA) and the interaction between the presence of markers of periodontal disease with adipokine in eRA individuals. Materials and methods Fifty-one patients...

Full description

Autores:
Cabrera Vargas, Luis Felipe
Torregrosa Almonacid, Lilian
Guevara, Óscar Alexander
Pedraza Ciro, Mauricio
Carrera, Javier A.
Villarreal, Ricardo A.
Vinck, Erick
Cabrera, Laura
Ferrada, Paula
Chen, Herbert
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/3748
Acceso en línea:
http://hdl.handle.net/20.500.12495/3748
https://doi.org/10.1016/j.amjsurg.2020.07.014
https://repositorio.unbosque.edu.co
Palabra clave:
Surgical smoke
Aerosol
Filter
COVID-19
Rights
openAccess
License
Acceso abierto
id UNBOSQUE2_7e5ae7fc7b06dcdfe4660664eb5c0dda
oai_identifier_str oai:repositorio.unbosque.edu.co:20.500.12495/3748
network_acronym_str UNBOSQUE2
network_name_str Repositorio U. El Bosque
repository_id_str
dc.title.spa.fl_str_mv Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery
dc.title.translated.spa.fl_str_mv Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery
title Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery
spellingShingle Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery
Surgical smoke
Aerosol
Filter
COVID-19
title_short Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery
title_full Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery
title_fullStr Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery
title_full_unstemmed Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery
title_sort Low-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgery
dc.creator.fl_str_mv Cabrera Vargas, Luis Felipe
Torregrosa Almonacid, Lilian
Guevara, Óscar Alexander
Pedraza Ciro, Mauricio
Carrera, Javier A.
Villarreal, Ricardo A.
Vinck, Erick
Cabrera, Laura
Ferrada, Paula
Chen, Herbert
dc.contributor.author.none.fl_str_mv Cabrera Vargas, Luis Felipe
Torregrosa Almonacid, Lilian
Guevara, Óscar Alexander
Pedraza Ciro, Mauricio
Carrera, Javier A.
Villarreal, Ricardo A.
Vinck, Erick
Cabrera, Laura
Ferrada, Paula
Chen, Herbert
dc.contributor.orcid.none.fl_str_mv Pedraza Ciro, Mauricio [0000-0001-8726-5578]
dc.subject.keywords.spa.fl_str_mv Surgical smoke
Aerosol
Filter
COVID-19
topic Surgical smoke
Aerosol
Filter
COVID-19
description Objective To establish the association between adipokine levels and markers of periodontal involvement as risk indicators of early stages of RA (eRA) and the interaction between the presence of markers of periodontal disease with adipokine in eRA individuals. Materials and methods Fifty-one patients with a diagnosis of eRA and 51 healthy controls matched for age and sex were studied. Clinical joint condition, clinical and serological markers of disease activity, serum adipokine levels (leptin, adiponectin, resistin, adipsin, vaspin, and IL-6), periodontal diagnosis, presence of Porphyromonas gingivalis, and related IgG1 and IgG2 antibodies were evaluated. Comparisons were made between eRA and healthy controls for periodontal indicators and adipokines. A subgroup analysis was realized with a non-conditional logistic regression to establish the association between the levels of leptin in individuals with eRA and controls according to the periodontal condition, presence of P. gingivalis, or high titers of IgG antibodies against P. gingivalis. Results The condition of overweight or obesity is associated with the diagnosis of eRA (p = 0.05), and these individuals also have higher levels of leptin (p = 0.001) and vaspin (p = 0.007). Higher frequency of P. gingivalis (p = 0.001) was found in the eRa group. Individuals with eRA with higher IgG2 titers against P. gingivalis had higher levels of leptin (OR: 1.66 (CI 95% 1.01–2.73)); however, individuals with periodontitis or P. gingivalis with eRA were associated with highest levels of leptin (OR: 1.86, CI 95% 1.19–24.3; and OR: 2.04, CI 95% 1.37–3 respectively). Conclusions eRA individuals have high levels of leptin and vaspin. However, the presence of periodontitis and related-periodontal disease markers showed an effect only in leptin levels in eRA individuals. Clinical relevance Emphasizing in personalized medicine, monitoring serum leptin levels and periodontitis markers can improve the early diagnosis of RA.
publishDate 2020
dc.date.accessioned.none.fl_str_mv 2020-08-10T20:22:07Z
dc.date.available.none.fl_str_mv 2020-08-10T20:22:07Z
dc.date.issued.none.fl_str_mv 2020
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.local.none.fl_str_mv Artículo de revista
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
format http://purl.org/coar/resource_type/c_6501
dc.identifier.issn.none.fl_str_mv 1879-1883
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/3748
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/j.amjsurg.2020.07.014
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv https://repositorio.unbosque.edu.co
identifier_str_mv 1879-1883
instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
url http://hdl.handle.net/20.500.12495/3748
https://doi.org/10.1016/j.amjsurg.2020.07.014
https://repositorio.unbosque.edu.co
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv American journal of surgery, 1879-1883, 2020
dc.relation.uri.none.fl_str_mv https://www.americanjournalofsurgery.com/article/S0002-9610(20)30443-8/fulltext
dc.rights.local.spa.fl_str_mv Acceso abierto
dc.rights.accessrights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
Acceso abierto
dc.rights.creativecommons.none.fl_str_mv 2020-07-22
rights_invalid_str_mv Acceso abierto
http://purl.org/coar/access_right/c_abf2
2020-07-22
eu_rights_str_mv openAccess
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Elsevier
dc.publisher.journal.spa.fl_str_mv Clinical oral investigations
American journal of surgery
institution Universidad El Bosque
bitstream.url.fl_str_mv https://repositorio.unbosque.edu.co/bitstreams/8052b7fc-51ec-4942-baba-e6b1b4205876/download
https://repositorio.unbosque.edu.co/bitstreams/3af0f88b-2155-4e6c-a376-22a9245e2817/download
https://repositorio.unbosque.edu.co/bitstreams/651c0fcb-02bd-45b3-a40c-cb6ed8937e8a/download
https://repositorio.unbosque.edu.co/bitstreams/bdd908c8-d163-49d5-b4a1-6cdcc5a6c9e0/download
bitstream.checksum.fl_str_mv 23ed47ea6d2c9e6dca5ad3f3f5583e4f
8a4605be74aa9ea9d79846c1fba20a33
7210a811635d1799e7c05fee5d259be7
973c928daf7724cf60f7a8a4fb79a15c
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio Institucional Universidad El Bosque
repository.mail.fl_str_mv bibliotecas@biteca.com
_version_ 1812134223822192640
spelling Cabrera Vargas, Luis FelipeTorregrosa Almonacid, LilianGuevara, Óscar AlexanderPedraza Ciro, MauricioCarrera, Javier A.Villarreal, Ricardo A.Vinck, ErickCabrera, LauraFerrada, PaulaChen, HerbertPedraza Ciro, Mauricio [0000-0001-8726-5578]2020-08-10T20:22:07Z2020-08-10T20:22:07Z20201879-1883http://hdl.handle.net/20.500.12495/3748https://doi.org/10.1016/j.amjsurg.2020.07.014instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquehttps://repositorio.unbosque.edu.coapplication/pdfengElsevierClinical oral investigationsAmerican journal of surgeryAmerican journal of surgery, 1879-1883, 2020https://www.americanjournalofsurgery.com/article/S0002-9610(20)30443-8/fulltextLow-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgeryLow-cost devices to prevent SARS-CoV-2 infection during open and laparoscopic surgeryArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85Surgical smokeAerosolFilterCOVID-19Objective To establish the association between adipokine levels and markers of periodontal involvement as risk indicators of early stages of RA (eRA) and the interaction between the presence of markers of periodontal disease with adipokine in eRA individuals. Materials and methods Fifty-one patients with a diagnosis of eRA and 51 healthy controls matched for age and sex were studied. Clinical joint condition, clinical and serological markers of disease activity, serum adipokine levels (leptin, adiponectin, resistin, adipsin, vaspin, and IL-6), periodontal diagnosis, presence of Porphyromonas gingivalis, and related IgG1 and IgG2 antibodies were evaluated. Comparisons were made between eRA and healthy controls for periodontal indicators and adipokines. A subgroup analysis was realized with a non-conditional logistic regression to establish the association between the levels of leptin in individuals with eRA and controls according to the periodontal condition, presence of P. gingivalis, or high titers of IgG antibodies against P. gingivalis. Results The condition of overweight or obesity is associated with the diagnosis of eRA (p = 0.05), and these individuals also have higher levels of leptin (p = 0.001) and vaspin (p = 0.007). Higher frequency of P. gingivalis (p = 0.001) was found in the eRa group. Individuals with eRA with higher IgG2 titers against P. gingivalis had higher levels of leptin (OR: 1.66 (CI 95% 1.01–2.73)); however, individuals with periodontitis or P. gingivalis with eRA were associated with highest levels of leptin (OR: 1.86, CI 95% 1.19–24.3; and OR: 2.04, CI 95% 1.37–3 respectively). Conclusions eRA individuals have high levels of leptin and vaspin. However, the presence of periodontitis and related-periodontal disease markers showed an effect only in leptin levels in eRA individuals. Clinical relevance Emphasizing in personalized medicine, monitoring serum leptin levels and periodontitis markers can improve the early diagnosis of RA.Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abierto2020-07-22ORIGINALCabrera Vargas, Torregrosa, L., Guevara, O._2020.pdfCabrera Vargas, Torregrosa, L., Guevara, O._2020.pdfapplication/pdf637715https://repositorio.unbosque.edu.co/bitstreams/8052b7fc-51ec-4942-baba-e6b1b4205876/download23ed47ea6d2c9e6dca5ad3f3f5583e4fMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/3af0f88b-2155-4e6c-a376-22a9245e2817/download8a4605be74aa9ea9d79846c1fba20a33MD52THUMBNAILCabrera Vargas, Torregrosa, L., Guevara, O._2020.pdf.jpgCabrera Vargas, Torregrosa, L., Guevara, O._2020.pdf.jpgimage/jpeg5775https://repositorio.unbosque.edu.co/bitstreams/651c0fcb-02bd-45b3-a40c-cb6ed8937e8a/download7210a811635d1799e7c05fee5d259be7MD53TEXTCabrera Vargas, Torregrosa, L., Guevara, O._2020.pdf.txtCabrera Vargas, Torregrosa, L., Guevara, O._2020.pdf.txtExtracted texttext/plain17298https://repositorio.unbosque.edu.co/bitstreams/bdd908c8-d163-49d5-b4a1-6cdcc5a6c9e0/download973c928daf7724cf60f7a8a4fb79a15cMD5420.500.12495/3748oai:repositorio.unbosque.edu.co:20.500.12495/37482024-02-07 02:58:30.52restrictedhttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.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