Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia
The ability of Pseudomonas aeruginosa to develop resistance to most antimicrobials represents an important clinical threat worldwide. We report the dissemination in several Colombian hospitals of two predominant lineages of extensively drug-resistant (XDR) carbapenemase-producing P. aeruginosa strai...
- Autores:
-
Correa, Adriana
del Campo, Rosa
Perenguez, Marcela
Blanco, Victor M.
Rodríguez-Baños, Mercedes
Perez, Federico
Maya, Juan J.
Rojas, Laura
Cantón, Rafael
Arias, Cesar A.
Villegas, María Virginia
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2020
- Institución:
- Universidad El Bosque
- Repositorio:
- Repositorio U. El Bosque
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.unbosque.edu.co:20.500.12495/3720
- Acceso en línea:
- http://hdl.handle.net/20.500.12495/3720
https://doi.org/10.1128/AAC.03926-14
https://repositorio.unbosque.edu.co
- Palabra clave:
- Infecciones por pseudomonas
Farmacorresistencia bacteriana
Colombia
- Rights
- openAccess
- License
- Acceso abierto
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| dc.title.spa.fl_str_mv |
Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia |
| dc.title.translated.spa.fl_str_mv |
Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia |
| title |
Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia |
| spellingShingle |
Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia Infecciones por pseudomonas Farmacorresistencia bacteriana Colombia |
| title_short |
Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia |
| title_full |
Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia |
| title_fullStr |
Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia |
| title_full_unstemmed |
Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia |
| title_sort |
Dissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in Colombia |
| dc.creator.fl_str_mv |
Correa, Adriana del Campo, Rosa Perenguez, Marcela Blanco, Victor M. Rodríguez-Baños, Mercedes Perez, Federico Maya, Juan J. Rojas, Laura Cantón, Rafael Arias, Cesar A. Villegas, María Virginia |
| dc.contributor.author.none.fl_str_mv |
Correa, Adriana del Campo, Rosa Perenguez, Marcela Blanco, Victor M. Rodríguez-Baños, Mercedes Perez, Federico Maya, Juan J. Rojas, Laura Cantón, Rafael Arias, Cesar A. Villegas, María Virginia |
| dc.contributor.orcid.none.fl_str_mv |
Villegas, María Virginia [0000-0003-1898-9067] |
| dc.subject.decs.spa.fl_str_mv |
Infecciones por pseudomonas Farmacorresistencia bacteriana Colombia |
| topic |
Infecciones por pseudomonas Farmacorresistencia bacteriana Colombia |
| description |
The ability of Pseudomonas aeruginosa to develop resistance to most antimicrobials represents an important clinical threat worldwide. We report the dissemination in several Colombian hospitals of two predominant lineages of extensively drug-resistant (XDR) carbapenemase-producing P. aeruginosa strains. These lineages belong to the high-risk clones sequence type 111 (ST111) and ST235 and harbor blaVIM-2 on a class 1 integron and blaKPC-2 on a Tn4401 transposon, respectively. Additionally, P. aeruginosa ST1492, a novel single-locus variant of ST111, was identified. Clonal dissemination and the presence of mobile genetic elements likely explain the successful spread of XDR P. aeruginosa strains in Colombia. |
| publishDate |
2020 |
| dc.date.accessioned.none.fl_str_mv |
2020-08-06T19:35:16Z |
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2020-08-06T19:35:16Z |
| dc.date.issued.none.fl_str_mv |
2020 |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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Artículo de revista |
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http://purl.org/coar/resource_type/c_6501 |
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info:eu-repo/semantics/article |
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http://purl.org/coar/resource_type/c_6501 |
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0066-4804 |
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http://hdl.handle.net/20.500.12495/3720 |
| dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.1128/AAC.03926-14 |
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instname:Universidad El Bosque |
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reponame:Repositorio Institucional Universidad El Bosque |
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https://repositorio.unbosque.edu.co |
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0066-4804 instname:Universidad El Bosque reponame:Repositorio Institucional Universidad El Bosque |
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http://hdl.handle.net/20.500.12495/3720 https://doi.org/10.1128/AAC.03926-14 https://repositorio.unbosque.edu.co |
| dc.language.iso.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartofseries.spa.fl_str_mv |
Antimicrobial agents and chemotherapy, 0066-4804, Vol. 59, Nro. 4, p. 2421-2425 |
| dc.relation.uri.none.fl_str_mv |
https://aac.asm.org/content/59/4/2421.long |
| dc.rights.local.spa.fl_str_mv |
Acceso abierto |
| dc.rights.accessrights.none.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 info:eu-repo/semantics/openAccess Acceso abierto |
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2015-04 |
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openAccess |
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application/pdf |
| dc.publisher.spa.fl_str_mv |
American Society for Microbiology |
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Antimicrobial agents and chemotherapy |
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Correa, Adrianadel Campo, RosaPerenguez, MarcelaBlanco, Victor M.Rodríguez-Baños, MercedesPerez, FedericoMaya, Juan J.Rojas, LauraCantón, RafaelArias, Cesar A.Villegas, María VirginiaVillegas, María Virginia [0000-0003-1898-9067]2020-08-06T19:35:16Z2020-08-06T19:35:16Z20200066-4804http://hdl.handle.net/20.500.12495/3720https://doi.org/10.1128/AAC.03926-14instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquehttps://repositorio.unbosque.edu.coapplication/pdfengAmerican Society for MicrobiologyAntimicrobial agents and chemotherapyAntimicrobial agents and chemotherapy, 0066-4804, Vol. 59, Nro. 4, p. 2421-2425https://aac.asm.org/content/59/4/2421.longDissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in ColombiaDissemination of high-risk clones of extensively drug-resistant pseudomonas aeruginosa in ColombiaArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85Infecciones por pseudomonasFarmacorresistencia bacterianaColombiaThe ability of Pseudomonas aeruginosa to develop resistance to most antimicrobials represents an important clinical threat worldwide. We report the dissemination in several Colombian hospitals of two predominant lineages of extensively drug-resistant (XDR) carbapenemase-producing P. aeruginosa strains. These lineages belong to the high-risk clones sequence type 111 (ST111) and ST235 and harbor blaVIM-2 on a class 1 integron and blaKPC-2 on a Tn4401 transposon, respectively. Additionally, P. aeruginosa ST1492, a novel single-locus variant of ST111, was identified. Clonal dissemination and the presence of mobile genetic elements likely explain the successful spread of XDR P. aeruginosa strains in Colombia.Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abierto2015-04LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/621ad2d8-650d-4132-9a6e-f9cbe8d8d539/download8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALCorrea, Adriana.pdfCorrea, Adriana.pdfapplication/pdf186855https://repositorio.unbosque.edu.co/bitstreams/9243efc1-e82e-4f1d-9751-d64510c8ccfb/download5c5efb1f095da824a267b2a76424b167MD51THUMBNAILCorrea, Adriana.pdf.jpgCorrea, Adriana.pdf.jpgimage/jpeg5775https://repositorio.unbosque.edu.co/bitstreams/e4568ea3-f245-4e95-be9b-b0cff65c761e/download7210a811635d1799e7c05fee5d259be7MD53TEXTCorrea, Adriana.pdf.txtCorrea, Adriana.pdf.txtExtracted texttext/plain34514https://repositorio.unbosque.edu.co/bitstreams/afa52974-2905-4f19-877d-d676686938b1/download15954e8ef321031f35e05cfad0f12031MD5420.500.12495/3720oai:repositorio.unbosque.edu.co:20.500.12495/37202024-02-07 00:40:55.858restrictedhttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.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 |