Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster

A patient with native valve endocarditis caused by a vancomycin "heteroresistant" strain of Enterococcus faecium experienced failure of daptomycin monotherapy without evidence of daptomycin resistance. The infecting organism exhibited in vivo emergence of a vancomycin-susceptible subpopula...

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Autores:
Arias, Cesar A.
Torres, Harrys A.
Singh, Kavindra V.
Panesso, Diana
Moore, Judson
Wanger, Audrey
Murray, Barbara E.
Tipo de recurso:
Article of journal
Fecha de publicación:
2007
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/5246
Acceso en línea:
http://hdl.handle.net/20.500.12495/5246
https://doi.org/10.1086/522656
https://repositorio.unbosque.edu.co
Palabra clave:
Rights
openAccess
License
Acceso abierto
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network_name_str Repositorio U. El Bosque
repository_id_str
dc.title.spa.fl_str_mv Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster
dc.title.translated.spa.fl_str_mv Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster
title Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster
spellingShingle Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster
title_short Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster
title_full Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster
title_fullStr Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster
title_full_unstemmed Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster
title_sort Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene cluster
dc.creator.fl_str_mv Arias, Cesar A.
Torres, Harrys A.
Singh, Kavindra V.
Panesso, Diana
Moore, Judson
Wanger, Audrey
Murray, Barbara E.
dc.contributor.author.none.fl_str_mv Arias, Cesar A.
Torres, Harrys A.
Singh, Kavindra V.
Panesso, Diana
Moore, Judson
Wanger, Audrey
Murray, Barbara E.
dc.contributor.orcid.none.fl_str_mv Panesso, Diana [0000-0002-4049-9702]
description A patient with native valve endocarditis caused by a vancomycin "heteroresistant" strain of Enterococcus faecium experienced failure of daptomycin monotherapy without evidence of daptomycin resistance. The infecting organism exhibited in vivo emergence of a vancomycin-susceptible subpopulation lacking vanA. Treatment with a combination of high-dose daptomycin, gentamicin, and high-dose ampicillin cleared the infection.
publishDate 2007
dc.date.issued.none.fl_str_mv 2007
dc.date.accessioned.none.fl_str_mv 2021-02-04T19:52:10Z
dc.date.available.none.fl_str_mv 2021-02-04T19:52:10Z
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.local.none.fl_str_mv Artículo de revista
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
format http://purl.org/coar/resource_type/c_6501
dc.identifier.issn.none.fl_str_mv 1537-6591
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/5246
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1086/522656
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv https://repositorio.unbosque.edu.co
identifier_str_mv 1537-6591
instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
url http://hdl.handle.net/20.500.12495/5246
https://doi.org/10.1086/522656
https://repositorio.unbosque.edu.co
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv Clinical Infectious Diseases, 1537-6591, Vol. 45, Nro. 10, 2007 p. 1343–1346
dc.relation.uri.none.fl_str_mv https://academic.oup.com/cid/article/45/10/1343/278162
dc.rights.local.spa.fl_str_mv Acceso abierto
dc.rights.accessrights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
Acceso abierto
dc.rights.creativecommons.none.fl_str_mv 2007
rights_invalid_str_mv Acceso abierto
http://purl.org/coar/access_right/c_abf2
2007
eu_rights_str_mv openAccess
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Oxford University Press
dc.publisher.journal.spa.fl_str_mv Clinical Infectious Diseases
institution Universidad El Bosque
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spelling Arias, Cesar A.Torres, Harrys A.Singh, Kavindra V.Panesso, DianaMoore, JudsonWanger, AudreyMurray, Barbara E.Panesso, Diana [0000-0002-4049-9702]2021-02-04T19:52:10Z2021-02-04T19:52:10Z20071537-6591http://hdl.handle.net/20.500.12495/5246https://doi.org/10.1086/522656instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquehttps://repositorio.unbosque.edu.coapplication/pdfengOxford University PressClinical Infectious DiseasesClinical Infectious Diseases, 1537-6591, Vol. 45, Nro. 10, 2007 p. 1343–1346https://academic.oup.com/cid/article/45/10/1343/278162Failure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene clusterFailure of daptomycin monotherapy for endocarditis caused by an Enterococcus faecium strain with vancomycin-resistant and vancomycin-susceptible subpopulations and evidence of in vivo loss of the vanA gene clusterArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85A patient with native valve endocarditis caused by a vancomycin "heteroresistant" strain of Enterococcus faecium experienced failure of daptomycin monotherapy without evidence of daptomycin resistance. The infecting organism exhibited in vivo emergence of a vancomycin-susceptible subpopulation lacking vanA. 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