Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report

Background Carbapenem-resistant Acinetobacter baumannii infections are a major public health problem worldwide, requiring the use of “old” antibiotics such as polymyxin B and E (colistin). However, there is concern regarding the emergence of isolates resistant to these antibiotics. Case presentation...

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Autores:
Robayo Amortegui, Henry
Corredor Rozo, Zayda Lorena
Carrasco Márquez, Adriana Marcela
Escobar-Pérez, Javier
García Casallas, Julio César
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/1689
Acceso en línea:
http://hdl.handle.net/20.500.12495/1689
https://doi.org/10.1186/s13256-019-2062-3
Palabra clave:
Colistina
Farmacorresistencia microbiana
Bacterias gramnegativas
Colombia
Bacteremia
Colistin resistance
Rights
License
Attribution 4.0 International
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network_name_str Repositorio U. El Bosque
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dc.title.spa.fl_str_mv Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report
title Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report
spellingShingle Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report
Colistina
Farmacorresistencia microbiana
Bacterias gramnegativas
Colombia
Bacteremia
Colistin resistance
title_short Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report
title_full Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report
title_fullStr Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report
title_full_unstemmed Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report
title_sort Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report
dc.creator.fl_str_mv Robayo Amortegui, Henry
Corredor Rozo, Zayda Lorena
Carrasco Márquez, Adriana Marcela
Escobar-Pérez, Javier
García Casallas, Julio César
dc.contributor.author.none.fl_str_mv Robayo Amortegui, Henry
Corredor Rozo, Zayda Lorena
Carrasco Márquez, Adriana Marcela
Escobar-Pérez, Javier
García Casallas, Julio César
dc.contributor.orcid.none.fl_str_mv Escobar-Pérez, Javier [0000-0002-0432-6978]
dc.subject.decs.spa.fl_str_mv Colistina
Farmacorresistencia microbiana
Bacterias gramnegativas
topic Colistina
Farmacorresistencia microbiana
Bacterias gramnegativas
Colombia
Bacteremia
Colistin resistance
dc.subject.keywords.spa.fl_str_mv Colombia
Bacteremia
Colistin resistance
description Background Carbapenem-resistant Acinetobacter baumannii infections are a major public health problem worldwide, requiring the use of “old” antibiotics such as polymyxin B and E (colistin). However, there is concern regarding the emergence of isolates resistant to these antibiotics. Case presentation We report a case of a 64-year-old mestizo man hospitalized in an intensive care unit of a health institution in Colombia with identification and clinical and molecular typing of a colistin- and carbapenem-resistant A. baumannii isolate with mechanisms of resistance to colistin not previously reported, causing bacteremia. Conclusions We have identified a strain of A. baumannii with mechanisms of resistance to colistin not previously reported in a patient with bacteremia who required treatment with multiple antibiotic schemes and had an adequate response.
publishDate 2019
dc.date.accessioned.none.fl_str_mv 2019-09-13T19:57:26Z
dc.date.available.none.fl_str_mv 2019-09-13T19:57:26Z
dc.date.issued.none.fl_str_mv 2019
dc.type.spa.fl_str_mv article
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dc.type.local.spa.fl_str_mv artículo
dc.identifier.issn.none.fl_str_mv 1752-1947
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/1689
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1186/s13256-019-2062-3
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
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identifier_str_mv 1752-1947
instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
repourl:https://repositorio.unbosque.edu.co
url http://hdl.handle.net/20.500.12495/1689
https://doi.org/10.1186/s13256-019-2062-3
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv Journal of Medical Case Reports, 1752-1947, Vol. 13, Nor, 141, 2019 p. 1-3
dc.relation.uri.none.fl_str_mv https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-019-2062-3
dc.rights.*.fl_str_mv Attribution 4.0 International
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dc.rights.local.spa.fl_str_mv Acceso abierto
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dc.rights.creativecommons.none.fl_str_mv 2019
rights_invalid_str_mv Attribution 4.0 International
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Acceso abierto
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2019
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dc.publisher.spa.fl_str_mv BioMed central
dc.publisher.journal.spa.fl_str_mv Journal of Medical Case Reports
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spelling Robayo Amortegui, HenryCorredor Rozo, Zayda LorenaCarrasco Márquez, Adriana MarcelaEscobar-Pérez, JavierGarcía Casallas, Julio CésarEscobar-Pérez, Javier [0000-0002-0432-6978]2019-09-13T19:57:26Z2019-09-13T19:57:26Z20191752-1947http://hdl.handle.net/20.500.12495/1689https://doi.org/10.1186/s13256-019-2062-3instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coapplication/pdfengBioMed centralJournal of Medical Case ReportsJournal of Medical Case Reports, 1752-1947, Vol. 13, Nor, 141, 2019 p. 1-3https://jmedicalcasereports.biomedcentral.com/articles/10.1186/s13256-019-2062-3Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Acceso abiertohttp://purl.org/coar/access_right/c_abf4542019http://purl.org/coar/access_right/c_abf2Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case reportarticleartículohttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501ColistinaFarmacorresistencia microbianaBacterias gramnegativasColombiaBacteremiaColistin resistanceBackground Carbapenem-resistant Acinetobacter baumannii infections are a major public health problem worldwide, requiring the use of “old” antibiotics such as polymyxin B and E (colistin). However, there is concern regarding the emergence of isolates resistant to these antibiotics. Case presentation We report a case of a 64-year-old mestizo man hospitalized in an intensive care unit of a health institution in Colombia with identification and clinical and molecular typing of a colistin- and carbapenem-resistant A. baumannii isolate with mechanisms of resistance to colistin not previously reported, causing bacteremia. Conclusions We have identified a strain of A. baumannii with mechanisms of resistance to colistin not previously reported in a patient with bacteremia who required treatment with multiple antibiotic schemes and had an adequate response.ORIGINALGarcia Casallas J.C., Robayo-Amortegui H._2019.pdfGarcia Casallas J.C., Robayo-Amortegui H._2019.pdfapplication/pdf306419https://repositorio.unbosque.edu.co/bitstreams/332eb777-03ae-4bc6-8591-f15252ba7265/download14477cd041e35a9410de2e1f0ee4748cMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8908https://repositorio.unbosque.edu.co/bitstreams/1dd3be61-7cb1-42bf-8796-ca85a269bfe5/download0175ea4a2d4caec4bbcc37e300941108MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/b2dfc48c-0d8a-4e68-9982-c062fb359208/download8a4605be74aa9ea9d79846c1fba20a33MD55THUMBNAILGarcia Casallas J.C., Robayo-Amortegui H._2019.pdf.jpgGarcia Casallas J.C., Robayo-Amortegui H._2019.pdf.jpgIM Thumbnailimage/jpeg10329https://repositorio.unbosque.edu.co/bitstreams/d2950597-a347-469a-b68a-a95e5afee0f2/download53c14d7d157a6711488e0f4e179ea678MD56TEXTGarcia Casallas J.C., Robayo-Amortegui H._2019.pdf.txtGarcia Casallas J.C., Robayo-Amortegui H._2019.pdf.txtExtracted texttext/plain18417https://repositorio.unbosque.edu.co/bitstreams/3d968bca-4161-4775-bf25-ce0f14ac1fb8/downloadeae04d68066ddc55d0d5ed5fc577b9ccMD5720.500.12495/1689oai:repositorio.unbosque.edu.co:20.500.12495/16892024-02-07 10:35:41.101http://creativecommons.org/licenses/by/4.0/Attribution 4.0 Internationalopen.accesshttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.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