Bacteremia by colistin-resistant acinetobacter baumannii isolate: a case report

Background Carbapenem-resistant Acinetobacter baumannii infections are a major public health problem worldwide, requiring the use of “old” antibiotics such as polymyxin B and E (colistin). However, there is concern regarding the emergence of isolates resistant to these antibiotics. Case presentation...

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Autores:
Robayo Amortegui, Henry
Corredor Rozo, Zayda Lorena
Carrasco Márquez, Adriana Marcela
Escobar-Pérez, Javier
García Casallas, Julio César
Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/1689
Acceso en línea:
http://hdl.handle.net/20.500.12495/1689
https://doi.org/10.1186/s13256-019-2062-3
Palabra clave:
Colistina
Farmacorresistencia microbiana
Bacterias gramnegativas
Colombia
Bacteremia
Colistin resistance
Rights
License
Attribution 4.0 International
Description
Summary:Background Carbapenem-resistant Acinetobacter baumannii infections are a major public health problem worldwide, requiring the use of “old” antibiotics such as polymyxin B and E (colistin). However, there is concern regarding the emergence of isolates resistant to these antibiotics. Case presentation We report a case of a 64-year-old mestizo man hospitalized in an intensive care unit of a health institution in Colombia with identification and clinical and molecular typing of a colistin- and carbapenem-resistant A. baumannii isolate with mechanisms of resistance to colistin not previously reported, causing bacteremia. Conclusions We have identified a strain of A. baumannii with mechanisms of resistance to colistin not previously reported in a patient with bacteremia who required treatment with multiple antibiotic schemes and had an adequate response.