Biosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombiano
La detección temprana de hepatitis B y C es crucial para mejorar los resultados en el trata-miento de estas enfermedades infecciosas. Este estudio evalúa la aplicabilidad de sensores moleculares —electroquímicos, colorimétricos y fluorimétricos— en el diagnóstico eficiente de estos virus en el conte...
- Autores:
-
Quintero Rivas, Sofia Alejandra
Vega Pérez , Flor Alejandra
Sarmiento Monsalve, Jeymy Tatiana
- Tipo de recurso:
- https://purl.org/coar/resource_type/c_7a1f
- Fecha de publicación:
- 2024
- Institución:
- Universidad El Bosque
- Repositorio:
- Repositorio U. El Bosque
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unbosque.edu.co:20.500.12495/13236
- Acceso en línea:
- https://hdl.handle.net/20.500.12495/13236
- Palabra clave:
- Hepatitis B
Hepatitis C
Sensores moleculares
Diagnóstico
Detección
Biosensores
Electroquímica
Colorimetría
Fluorimetría
Biomarcadores
615.19
Hepatitis B
Hepatitis C
Molecular Sensors
Diagnosis
Detection
Biosensors
Electrochemistry
Colorimetry
Fluorimetry
Biomarkers
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 International
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UNBOSQUE2 |
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Repositorio U. El Bosque |
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| dc.title.none.fl_str_mv |
Biosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombiano |
| dc.title.translated.none.fl_str_mv |
Molecular biosensors (colorimetric, fluorimetric or electrochemical) for the detection of hepatitis B and C: Current status and perspectives in the Colombian context |
| title |
Biosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombiano |
| spellingShingle |
Biosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombiano Hepatitis B Hepatitis C Sensores moleculares Diagnóstico Detección Biosensores Electroquímica Colorimetría Fluorimetría Biomarcadores 615.19 Hepatitis B Hepatitis C Molecular Sensors Diagnosis Detection Biosensors Electrochemistry Colorimetry Fluorimetry Biomarkers |
| title_short |
Biosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombiano |
| title_full |
Biosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombiano |
| title_fullStr |
Biosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombiano |
| title_full_unstemmed |
Biosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombiano |
| title_sort |
Biosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombiano |
| dc.creator.fl_str_mv |
Quintero Rivas, Sofia Alejandra Vega Pérez , Flor Alejandra Sarmiento Monsalve, Jeymy Tatiana |
| dc.contributor.advisor.none.fl_str_mv |
Sarmiento Monsalve, Jeymy Tatiana |
| dc.contributor.author.none.fl_str_mv |
Quintero Rivas, Sofia Alejandra Vega Pérez , Flor Alejandra Sarmiento Monsalve, Jeymy Tatiana |
| dc.subject.none.fl_str_mv |
Hepatitis B Hepatitis C Sensores moleculares Diagnóstico Detección Biosensores Electroquímica Colorimetría Fluorimetría Biomarcadores |
| topic |
Hepatitis B Hepatitis C Sensores moleculares Diagnóstico Detección Biosensores Electroquímica Colorimetría Fluorimetría Biomarcadores 615.19 Hepatitis B Hepatitis C Molecular Sensors Diagnosis Detection Biosensors Electrochemistry Colorimetry Fluorimetry Biomarkers |
| dc.subject.ddc.none.fl_str_mv |
615.19 |
| dc.subject.keywords.none.fl_str_mv |
Hepatitis B Hepatitis C Molecular Sensors Diagnosis Detection Biosensors Electrochemistry Colorimetry Fluorimetry Biomarkers |
| description |
La detección temprana de hepatitis B y C es crucial para mejorar los resultados en el trata-miento de estas enfermedades infecciosas. Este estudio evalúa la aplicabilidad de sensores moleculares —electroquímicos, colorimétricos y fluorimétricos— en el diagnóstico eficiente de estos virus en el contexto colombiano. Se realizó una revisión exhaustiva de la literatura, recopilando 109 artículos académicos, de los cuales 27 se enfocan en sensores moleculares desde 2010. Los hallazgos revelan que estos sensores ofrecen ventajas significativas en limites de detección y tiempos de respuesta frente a métodos convencionales, además de facilitar la diferenciación entre los virus. La capacidad de interacción efectiva con las moléculas diana optimiza su uso diagnóstico. En conclusión, los biosensores moleculares se presentan como alternativas viables para el diagnóstico temprano de hepatitis B y C. Se recomienda que futuras investigaciones se concentren en su implementación en el sistema de salud colom-biano para mejorar la efectividad diagnóstica y prevenir complicaciones severas. |
| publishDate |
2024 |
| dc.date.accessioned.none.fl_str_mv |
2024-11-19T14:16:05Z |
| dc.date.available.none.fl_str_mv |
2024-11-19T14:16:05Z |
| dc.date.issued.none.fl_str_mv |
2024-10 |
| dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_7a1f |
| dc.type.local.none.fl_str_mv |
Tesis/Trabajo de grado - Monografía - Pregrado |
| dc.type.coar.none.fl_str_mv |
https://purl.org/coar/resource_type/c_7a1f |
| dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/bachelorThesis |
| dc.type.coarversion.none.fl_str_mv |
https://purl.org/coar/version/c_ab4af688f83e57aa |
| format |
https://purl.org/coar/resource_type/c_7a1f |
| dc.identifier.uri.none.fl_str_mv |
https://hdl.handle.net/20.500.12495/13236 |
| dc.identifier.instname.spa.fl_str_mv |
Universidad El Bosque |
| dc.identifier.reponame.spa.fl_str_mv |
reponame:Repositorio Institucional Universidad El Bosque |
| dc.identifier.repourl.none.fl_str_mv |
repourl:https://repositorio.unbosque.edu.co |
| url |
https://hdl.handle.net/20.500.12495/13236 |
| identifier_str_mv |
Universidad El Bosque reponame:Repositorio Institucional Universidad El Bosque repourl:https://repositorio.unbosque.edu.co |
| dc.language.iso.fl_str_mv |
spa |
| language |
spa |
| dc.relation.references.none.fl_str_mv |
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Sarmiento Monsalve, Jeymy TatianaQuintero Rivas, Sofia AlejandraVega Pérez , Flor AlejandraSarmiento Monsalve, Jeymy Tatiana2024-11-19T14:16:05Z2024-11-19T14:16:05Z2024-10https://hdl.handle.net/20.500.12495/13236Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coLa detección temprana de hepatitis B y C es crucial para mejorar los resultados en el trata-miento de estas enfermedades infecciosas. Este estudio evalúa la aplicabilidad de sensores moleculares —electroquímicos, colorimétricos y fluorimétricos— en el diagnóstico eficiente de estos virus en el contexto colombiano. Se realizó una revisión exhaustiva de la literatura, recopilando 109 artículos académicos, de los cuales 27 se enfocan en sensores moleculares desde 2010. Los hallazgos revelan que estos sensores ofrecen ventajas significativas en limites de detección y tiempos de respuesta frente a métodos convencionales, además de facilitar la diferenciación entre los virus. La capacidad de interacción efectiva con las moléculas diana optimiza su uso diagnóstico. En conclusión, los biosensores moleculares se presentan como alternativas viables para el diagnóstico temprano de hepatitis B y C. Se recomienda que futuras investigaciones se concentren en su implementación en el sistema de salud colom-biano para mejorar la efectividad diagnóstica y prevenir complicaciones severas.PregradoQuímico FarmacéuticoEarly detection of hepatitis B and C is essential for improving treatment outcomes for these infectious diseases. This study assesses the applicability of molecular sensors—electrochemical, colorimetric, and fluorimetric—for efficient diagnosis of these viruses within the Colombian context. A comprehensive literature review was conducted, compiling 109 academic articles, of which 27 focus on molecular sensors published since 2010. The findings indicate that these sensors offer significant advantages in detection limits and response times over conventional methods, as well as facilitating differentiation between the viruses. Their effective interaction with target molecules enhances diagnostic applicability. In conclusion, molecular biosensors emerge as viable alternatives for the early diagnosis of hepatitis B and C. Future research is recommended to focus on their implementation in the Colombian healthcare system to improve diagnostic effectiveness and prevent severe complications.application/pdfAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/Acceso abiertohttps://purl.org/coar/access_right/c_abf2http://purl.org/coar/access_right/c_abf2Hepatitis BHepatitis CSensores molecularesDiagnósticoDetecciónBiosensoresElectroquímicaColorimetríaFluorimetríaBiomarcadores615.19Hepatitis BHepatitis CMolecular SensorsDiagnosisDetectionBiosensorsElectrochemistryColorimetryFluorimetryBiomarkersBiosensores moleculares (colorimétricos, fluorimétricos o electroquímicos) para la detección de hepatitis B y C: Estado actual y perspectivas en el contexto colombianoMolecular biosensors (colorimetric, fluorimetric or electrochemical) for the detection of hepatitis B and C: Current status and perspectives in the Colombian contextQuímica FarmacéuticaUniversidad El BosqueFacultad de CienciasTesis/Trabajo de grado - Monografía - Pregradohttps://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesishttps://purl.org/coar/version/c_ab4af688f83e57aa[1] L. Salas Zapata, “Dirección de Promoción y Prevención Grupo de Sexualidad, Derechos Sexuales y Derechos Reproductivos Grupo de endemo-epidémicas,” 2020. [Online]. Available: https://www.ins.gov.co/buscador-[2] C. Shih, C. C. Yang, G. Choijilsuren, C. H. Chang, and A. T. Liou, “Hepatitis B Virus,” Trends Microbiol, vol. 26, no. 4, pp. 386–387, Apr. 2018, doi: 10.1016/j.tim.2018.01.009.[3] N. Echeverría, G. Moratorio, J. Cristina, and P. Moreno, “Hepatitis C virus genetic variability and evolution,” World J Hepatol, vol. 7, no. 6, p. 831, Apr. 2015, doi: 10.4254/WJH.V7.I6.831.[4] D. Castaneda, A. J. Gonzalez, M. Alomari, K. Tandon, and X. B. Zervos, “From hepatitis A to E: A critical review of viral hepatitis,” Apr. 28, 2021, Baishideng Publishing Group Co. doi: 10.3748/wjg.v27.i16.1691.[5] Organización Mundial de la Salud, “La OMS da la alarma sobre las hepatitis víricas que se cobran 3500 vidas al día.” Accessed: Jun. 25, 2024. [Online]. Available: https://www.who.int/es/news/item/09-04-2024-who-sounds-alarm-on-viral-hepatitis-infections-claiming-3500-lives-each-day[6] H. Sepúlveda, “Informe de evento. Hepatitis B, C y coinfección B-D. Periodo epidemiológico III. Colombia, 2023,” 2023. [Online]. Available: www.ins.gov.co[7] D. Romero and L. Daza, “Protocolo de Vigilancia de Hepatitis B, C y coinfección/superinfección Hepatitis B-Delta Protocolo de Vigilancia de,” 2022, doi: 10.33610/infoeventos.56.[8] M. Makvandi, “Update on occult hepatitis B virus infection,” Oct. 21, 2016, Baishideng Publishing Group Co. doi: 10.3748/wjg.v22.i39.8720.[9] Ö. Kirişci and A. Calıskan, “Threshold value of the anti-HCV test in the diagnosis of HCV infection,” The Journal of Infection in Developing Countries, vol. 13, no. 10, pp. 914–919, Oct. 2019, doi: 10.3855/jidc.11657.[10] J. Uribe et al., “Guía de Práctica Clínica Para la tamización, diagnóstico y tratamiento de personas con infección por el virus de la hepatitis C,” 2018, Accessed: Nov. 17, 2023. [Online]. Available: https://www.acin.org/images/guias/GPC_Hep_C_2018_FINAL.pdf[11] C. Abella, “Guía para la vigilancia por laboratorio de hepatitis virales,” 2019, Accessed: Jul. 13, 2023. [Online]. Available: https://www.ins.gov.co/buscador-eventos/Informacin%20de%20laboratorio/Guia-Vigilancia-por-Laboratorio-Hepatitis-Virales.pdf[12] I. García-Bermejo and F. de Ory, “Diagnóstico rápido en serología,” Enferm Infecc Microbiol Clin, vol. 35, no. 4, pp. 246–254, Apr. 2017, doi: 10.1016/J.EIMC.2016.12.013.[13] N. Hasaneen, S. Akhtarian, R. Pulicharla, S. K. Brar, and P. Rezai, “Surface molecularly imprinted polymer-based sensors for antibiotic detection,” TrAC Trends in Analytical Chemistry, vol. 170, p. 117389, Jan. 2024, doi: 10.1016/J.TRAC.2023.117389.[14] N. Chauhan, T. Maekawa, and D. N. S. Kumar, “Graphene based biosensors - Accelerating medical diagnostics to new-dimensions,” Aug. 14, 2017, Cambridge University Press. doi: 10.1557/jmr.2017.91.[15] M. Derakhshan, E. Molaakbari, T. Shamspur, and A. Mostafavi, “Novel hybridization indicator for DNA sequences related to the hepatitis B virus: Electrochemical and in-silico approach,” Microchemical Journal, vol. 193, p. 109118, Oct. 2023, doi: 10.1016/J.MICROC.2023.109118.[16] T. Beduk et al., “A Portable Molecularly Imprinted Sensor for On-Site and Wireless Environmental Bisphenol A Monitoring,” Front Chem, vol. 10, p. 833899, Feb. 2022, doi: 10.3389/FCHEM.2022.833899/BIBTEX.[17] M. Heiat, R. Ranjbar, ; Seyed, and M. Alavian, “Classical and Modern Approaches Used for Viral Hepatitis Diagnosis,” vol. 14, no. 4, p. 17632, 2014, doi: 10.5812/hepatmon.17632.[18] J. I. Marín and A. Toro, “Biomarcadores convencionales y emergentes en hepatitis B.” Accessed: Jun. 27, 2024. [Online]. Available: https://revistahepatologia.org/index.php/hepa/article/view/82/66[19] M. A. Odenwald and S. Paul, “Viral hepatitis: Past, present, and future,” World J Gastroenterol, vol. 28, no. 14, p. 1405, Apr. 2022, doi: 10.3748/WJG.V28.I14.1405.[20] S. Tsukuda and K. Watashi, “Hepatitis B virus biology and life cycle,” Antiviral Res, vol. 182, p. 104925, Oct. 2020, doi: 10.1016/J.ANTIVIRAL.2020.104925.[21] A. Gaviria et al., “Guía de Práctica Clínica Diagnostivo y tratamiento de Hepatitis B crónica,” 2016, Accessed: Nov. 17, 2023. [Online]. Available: https://www.hepb.org/assets/Uploads/GPC-Hep-B.pdf[22] A. I. Toro and J. C. Gutiérrez, “Hepatitis B,” vol. 17, pp. 7–8, 2011.[23] S. Nate and J. Pavan, “BIOLOGÍA DE LOS VIRUS,” vol. 1, 2019.[24] M. Guvenir and A. Arikan, “Hepatitis B virus: From Diagnosis to Treatment,” Dec. 01, 2020, Polish Society of Microbiolo-gists. doi: 10.33073/PJM-2020-044.[25] M. 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Fu, “Biosensors for hepatitis B virus detection,” World J Gastroenterol, vol. 20, no. 35, p. 12485, Sep. 2014, doi: 10.3748/wjg.v20.i35.12485.https://docs.google.com/spreadsheets/d/1_p_41rZbXzBUV80FUdXyTyW3-yEEWYQD-X5Y8YbW0HQ/edit?usp=sharingspaLICENSElicense.txtlicense.txttext/plain; charset=utf-82000https://repositorio.unbosque.edu.co/bitstreams/a2817912-00b9-45d3-9f8e-c6cf1697df64/download17cc15b951e7cc6b3728a574117320f9MD51Acta de aprobacion.pdfapplication/pdf1006359https://repositorio.unbosque.edu.co/bitstreams/bc91579a-b757-46da-a208-135a4abb50c0/download47c663c92589b38dd6c5fe930ea69b42MD512Carta de autorizacion.pdfapplication/pdf208549https://repositorio.unbosque.edu.co/bitstreams/dc789d10-f59b-4643-850c-c346081fb767/downloadaf75fd5a990f38c4d8774a5e758bcafdMD513ORIGINALTrabajo de grado.pdfTrabajo de grado.pdfapplication/pdf1093494https://repositorio.unbosque.edu.co/bitstreams/b6ae6dc4-ae5c-4893-8baa-4e1ea1915ebb/download9832b799035b6c42f88d9d6ed8fd500fMD53Anexo 1. 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