Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions

High-dose daptomycin (DAP) therapy failed in a neutropenic patient with bloodstream infection caused by a DAP-susceptible Enterococcus faecium (minimum inhibitory concentration, 3 μg/mL) harboring genetic changes associated with DAP resistance, with persistent bacteremia and selection of additional...

Full description

Autores:
Munita, Jose M.
Mishra, Nagendra N.
Alvarez, Danya
Tran, Truc T.
Diaz, Lorena
Panesso, Diana
Reyes, Jinnethe
Murray, Barbara E.
Adachi, Javier A.
Bayer, Arnold S.
Arias, Cesar A.
Tipo de recurso:
Article of journal
Fecha de publicación:
2014
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/3347
Acceso en línea:
http://hdl.handle.net/20.500.12495/3347
https://repositorio.unbosque.edu.co
Palabra clave:
Daptomicina
Enterococcus faecium
Tratamientos
Daptomycin
Enterococcus faecium
Resistance
Treatment failure
Rights
openAccess
License
Acceso abierto
id UNBOSQUE2_288dcbedb4aa82ae9b9a14d18104cf6c
oai_identifier_str oai:repositorio.unbosque.edu.co:20.500.12495/3347
network_acronym_str UNBOSQUE2
network_name_str Repositorio U. El Bosque
repository_id_str
dc.title.spa.fl_str_mv Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions
title Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions
spellingShingle Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions
Daptomicina
Enterococcus faecium
Tratamientos
Daptomycin
Enterococcus faecium
Resistance
Treatment failure
title_short Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions
title_full Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions
title_fullStr Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions
title_full_unstemmed Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions
title_sort Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions
dc.creator.fl_str_mv Munita, Jose M.
Mishra, Nagendra N.
Alvarez, Danya
Tran, Truc T.
Diaz, Lorena
Panesso, Diana
Reyes, Jinnethe
Murray, Barbara E.
Adachi, Javier A.
Bayer, Arnold S.
Arias, Cesar A.
dc.contributor.author.none.fl_str_mv Munita, Jose M.
Mishra, Nagendra N.
Alvarez, Danya
Tran, Truc T.
Diaz, Lorena
Panesso, Diana
Reyes, Jinnethe
Murray, Barbara E.
Adachi, Javier A.
Bayer, Arnold S.
Arias, Cesar A.
dc.contributor.orcid.none.fl_str_mv Panesso, Diana [0000-0002-4049-9702]
dc.subject.decs.spa.fl_str_mv Daptomicina
Enterococcus faecium
Tratamientos
topic Daptomicina
Enterococcus faecium
Tratamientos
Daptomycin
Enterococcus faecium
Resistance
Treatment failure
dc.subject.keywords.spa.fl_str_mv Daptomycin
Enterococcus faecium
Resistance
Treatment failure
description High-dose daptomycin (DAP) therapy failed in a neutropenic patient with bloodstream infection caused by a DAP-susceptible Enterococcus faecium (minimum inhibitory concentration, 3 μg/mL) harboring genetic changes associated with DAP resistance, with persistent bacteremia and selection of additional resistances. Daptomycin monotherapy should be used cautiously against DAP-susceptible E. faecium strains with minimum inhibitory concentrations >2 μg/mL.
publishDate 2014
dc.date.issued.none.fl_str_mv 2014
dc.date.accessioned.none.fl_str_mv 2020-07-07T16:47:26Z
dc.date.available.none.fl_str_mv 2020-07-07T16:47:26Z
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.local.none.fl_str_mv Artículo de revista
dc.type.coar.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.driver.none.fl_str_mv info:eu-repo/semantics/article
format http://purl.org/coar/resource_type/c_6501
dc.identifier.issn.none.fl_str_mv 1058-4838
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/3347
dc.identifier.doi.none.fl_str_mv 10.1093/cid/ciu642
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv https://repositorio.unbosque.edu.co
identifier_str_mv 1058-4838
10.1093/cid/ciu642
instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
url http://hdl.handle.net/20.500.12495/3347
https://repositorio.unbosque.edu.co
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv Clinical Infectious Diseases, 1058-4838, Vol. 59, Nro. 9, 2014, p. 1277–1280
dc.relation.uri.none.fl_str_mv https://academic.oup.com/cid/article/59/9/1277/424852
dc.rights.local.spa.fl_str_mv Acceso abierto
dc.rights.accessrights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
Acceso abierto
dc.rights.creativecommons.none.fl_str_mv 2014
rights_invalid_str_mv Acceso abierto
http://purl.org/coar/access_right/c_abf2
2014
eu_rights_str_mv openAccess
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Oxford University Press
dc.publisher.journal.spa.fl_str_mv Clinical Infectious Diseases
institution Universidad El Bosque
bitstream.url.fl_str_mv https://repositorio.unbosque.edu.co/bitstreams/ac92132a-e82b-43dd-9ad9-a39f773413ab/download
https://repositorio.unbosque.edu.co/bitstreams/def66bc7-4e6b-4c1d-8143-bc4c40fe6316/download
https://repositorio.unbosque.edu.co/bitstreams/e433ec09-34dd-4a70-bf7e-c6db6ac390e1/download
https://repositorio.unbosque.edu.co/bitstreams/525d42f4-51af-4dc9-9424-1aac65c9d7ea/download
bitstream.checksum.fl_str_mv 7a2141304375d1711076076f7366a2bb
8a4605be74aa9ea9d79846c1fba20a33
b026eccdb0f1a574b86e08915b6c1c2c
efb09fb39a369a6fcc5fc9d311c852f9
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio Institucional Universidad El Bosque
repository.mail.fl_str_mv bibliotecas@biteca.com
_version_ 1814100761785663488
spelling Munita, Jose M.Mishra, Nagendra N.Alvarez, DanyaTran, Truc T.Diaz, LorenaPanesso, DianaReyes, JinnetheMurray, Barbara E.Adachi, Javier A.Bayer, Arnold S.Arias, Cesar A.Panesso, Diana [0000-0002-4049-9702]2020-07-07T16:47:26Z2020-07-07T16:47:26Z20141058-4838http://hdl.handle.net/20.500.12495/334710.1093/cid/ciu642instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquehttps://repositorio.unbosque.edu.coapplication/pdfengOxford University PressClinical Infectious DiseasesClinical Infectious Diseases, 1058-4838, Vol. 59, Nro. 9, 2014, p. 1277–1280https://academic.oup.com/cid/article/59/9/1277/424852Failure of High-Dose Daptomycin for Bacteremia Caused by Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR SubstitutionsArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85DaptomicinaEnterococcus faeciumTratamientosDaptomycinEnterococcus faeciumResistanceTreatment failureHigh-dose daptomycin (DAP) therapy failed in a neutropenic patient with bloodstream infection caused by a DAP-susceptible Enterococcus faecium (minimum inhibitory concentration, 3 μg/mL) harboring genetic changes associated with DAP resistance, with persistent bacteremia and selection of additional resistances. Daptomycin monotherapy should be used cautiously against DAP-susceptible E. faecium strains with minimum inhibitory concentrations >2 μg/mL.Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abierto2014ORIGINALMunita_Jose_M_2014.pdfMunita_Jose_M_2014.pdfapplication/pdf287451https://repositorio.unbosque.edu.co/bitstreams/ac92132a-e82b-43dd-9ad9-a39f773413ab/download7a2141304375d1711076076f7366a2bbMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/def66bc7-4e6b-4c1d-8143-bc4c40fe6316/download8a4605be74aa9ea9d79846c1fba20a33MD52THUMBNAILMunita_Jose_M_2014.pdf.jpgMunita_Jose_M_2014.pdf.jpgIM Thumbnailimage/jpeg13300https://repositorio.unbosque.edu.co/bitstreams/e433ec09-34dd-4a70-bf7e-c6db6ac390e1/downloadb026eccdb0f1a574b86e08915b6c1c2cMD53TEXTMunita_Jose_M_2014.pdf.txtMunita_Jose_M_2014.pdf.txtExtracted texttext/plain22574https://repositorio.unbosque.edu.co/bitstreams/525d42f4-51af-4dc9-9424-1aac65c9d7ea/downloadefb09fb39a369a6fcc5fc9d311c852f9MD5420.500.12495/3347oai:repositorio.unbosque.edu.co:20.500.12495/33472024-02-07 03:35:26.509restrictedhttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.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