Bola grasa de Bichat como una fuente potencial de células troncales mesenquimales. Revisión de la literatura. Extracción de datos

Mesenchyme stem cells obtained underneath adipose tissue are a promising cellular source for tissue engineering due to their abundance in the human body. This cellular population possesses self-renovation, differentiation, multi-lineage and high proliferation potential which makes it ideal for isolation, characterisation and expansion. The Buccal Fat Pad (BFP) represents a source of stem cells which are easy to access, from which adipose tissue stem cells have been isolated and their extraction is by means of a minimally-invasive or complicated procedure for the patient. The present review is aimed at studying the published scientific evidence, anatomical, histological and physiological characteristics of the BFP, as well the protocols which have reported its isolation, characterisation, expansion, proliferation and differentiation. Also, to identify their clinical applications in dentistry and regenerative medicine. Three electronic searches of PUBMED were carried out, one for each topic of the revision; each had different strategies with their respective key words, as well as manual, reference searches and all articles with complete texts were selected without restriction of language, place or publishing date. The selected studies were in vivo, in vitro, case reports and descriptive studies. A table was developed for each topic for data collection from each article and from these the revision was redacted following the scientific parameters established in the European Association of Science Editors (EASE). It has been shown that the BFP-ASCs have a morphology which is characteristic of adipose tissue in comparison with subcutaneous fat stem cells; they have proliferative characteristics similar to dental pulp and subcutaneous fat stem cells, as well as being a great source and easily accessible type of said cells for maxilla-facial surgeons which can be the focus of future research with clinical and therapeutic objectives.

• Autores: Martínez Carreño, Miguel Ángel; Fajardo Báez, Paula Andrea
• Tipo de recurso: Trabajo de grado de pregrado
• Fecha de publicación: 2018
• Institución: Universidad El Bosque
• Repositorio: Repositorio U. El Bosque
• Idioma: spa
• OAI Identifier: oai:repositorio.unbosque.edu.co:20.500.12495/2228
• Acceso en línea: http://hdl.handle.net/20.500.12495/2228
• Palabra clave: Ingeniería de tejidos
• Rights: openAccess
• License: Attribution-NonCommercial-ShareAlike 4.0 International