The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia

There is a lack of population based studies of autoimmune encephalitis (AE) in Latin American countries, especially in Colombia. The aim of this study is to characterize patients with AE managed in three centers in Bogotá-Colombia, emphasizing on antibody profile. We conducted a retrospective case-s...

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Autores:
Moutran Barroso, Habib
Kreinter Rosembaun, Hellen
Beltrán S, Maria Alejandra
Bayona, Hernán
Mayor, Luis Carlos
Tipo de recurso:
Article of journal
Fecha de publicación:
2021
Institución:
Universidad El Bosque
Repositorio:
Repositorio U. El Bosque
Idioma:
eng
OAI Identifier:
oai:repositorio.unbosque.edu.co:20.500.12495/5553
Acceso en línea:
http://hdl.handle.net/20.500.12495/5553
https://doi.org/10.1016/J.JNEUROIM.2020.577451
Palabra clave:
Autoimmune encephalitis
Epilepsy
Anti-NMDA
LGI1
Paraneoplastic encephalitis
Rights
openAccess
License
Acceso abierto
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dc.title.spa.fl_str_mv The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia
dc.title.translated.spa.fl_str_mv The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia
title The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia
spellingShingle The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia
Autoimmune encephalitis
Epilepsy
Anti-NMDA
LGI1
Paraneoplastic encephalitis
title_short The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia
title_full The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia
title_fullStr The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia
title_full_unstemmed The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia
title_sort The multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, Colombia
dc.creator.fl_str_mv Moutran Barroso, Habib
Kreinter Rosembaun, Hellen
Beltrán S, Maria Alejandra
Bayona, Hernán
Mayor, Luis Carlos
dc.contributor.author.none.fl_str_mv Moutran Barroso, Habib
Kreinter Rosembaun, Hellen
Beltrán S, Maria Alejandra
Bayona, Hernán
Mayor, Luis Carlos
dc.subject.keywords.spa.fl_str_mv Autoimmune encephalitis
Epilepsy
Anti-NMDA
LGI1
Paraneoplastic encephalitis
topic Autoimmune encephalitis
Epilepsy
Anti-NMDA
LGI1
Paraneoplastic encephalitis
description There is a lack of population based studies of autoimmune encephalitis (AE) in Latin American countries, especially in Colombia. The aim of this study is to characterize patients with AE managed in three centers in Bogotá-Colombia, emphasizing on antibody profile. We conducted a retrospective case-series study, including 9 patients. The most prevalent antibody found was NMDAR, followed by LGI1. Some distinguishing features included: faciobrachial dystonia and hyponatremia in LGI1, a younger age and good outcome in NMDAR, a notable response to steroids in anti TPO-Thyroglobulin, a cerebellar syndrome associated with Anti-Yo, and epilepsy with insomnia in CASPR2.
publishDate 2021
dc.date.accessioned.none.fl_str_mv 2021-03-05T14:35:59Z
dc.date.available.none.fl_str_mv 2021-03-05T14:35:59Z
dc.date.issued.none.fl_str_mv 2021
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dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.local.none.fl_str_mv Artículo de revista
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dc.identifier.issn.none.fl_str_mv 1872-8421
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/20.500.12495/5553
dc.identifier.doi.none.fl_str_mv https://doi.org/10.1016/J.JNEUROIM.2020.577451
dc.identifier.instname.spa.fl_str_mv instname:Universidad El Bosque
dc.identifier.reponame.spa.fl_str_mv reponame:Repositorio Institucional Universidad El Bosque
dc.identifier.repourl.none.fl_str_mv repourl:https://repositorio.unbosque.edu.co
identifier_str_mv 1872-8421
instname:Universidad El Bosque
reponame:Repositorio Institucional Universidad El Bosque
repourl:https://repositorio.unbosque.edu.co
url http://hdl.handle.net/20.500.12495/5553
https://doi.org/10.1016/J.JNEUROIM.2020.577451
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.ispartofseries.spa.fl_str_mv Journal of Neuroimmunology, 1872-8421, Vol. 350, 2021, p. 577451
dc.relation.uri.none.fl_str_mv https://www.jni-journal.com/article/S0165-5728(20)30712-8/fulltext
dc.rights.local.spa.fl_str_mv Acceso abierto
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Acceso abierto
dc.rights.creativecommons.none.fl_str_mv 2021
rights_invalid_str_mv Acceso abierto
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2021
eu_rights_str_mv openAccess
dc.format.mimetype.none.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Elsevier B.V.
dc.publisher.journal.spa.fl_str_mv Journal of Neuroimmunology
institution Universidad El Bosque
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spelling Moutran Barroso, HabibKreinter Rosembaun, HellenBeltrán S, Maria AlejandraBayona, HernánMayor, Luis Carlos2021-03-05T14:35:59Z2021-03-05T14:35:59Z20211872-8421http://hdl.handle.net/20.500.12495/5553https://doi.org/10.1016/J.JNEUROIM.2020.577451instname:Universidad El Bosquereponame:Repositorio Institucional Universidad El Bosquerepourl:https://repositorio.unbosque.edu.coapplication/pdfengElsevier B.V.Journal of NeuroimmunologyJournal of Neuroimmunology, 1872-8421, Vol. 350, 2021, p. 577451https://www.jni-journal.com/article/S0165-5728(20)30712-8/fulltextThe multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, ColombiaThe multiple faces of encephalitis: Antibody profile in a case series of autoimmune encephalitis in Bogotá, ColombiaArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85Autoimmune encephalitisEpilepsyAnti-NMDALGI1Paraneoplastic encephalitisThere is a lack of population based studies of autoimmune encephalitis (AE) in Latin American countries, especially in Colombia. The aim of this study is to characterize patients with AE managed in three centers in Bogotá-Colombia, emphasizing on antibody profile. We conducted a retrospective case-series study, including 9 patients. The most prevalent antibody found was NMDAR, followed by LGI1. Some distinguishing features included: faciobrachial dystonia and hyponatremia in LGI1, a younger age and good outcome in NMDAR, a notable response to steroids in anti TPO-Thyroglobulin, a cerebellar syndrome associated with Anti-Yo, and epilepsy with insomnia in CASPR2.Acceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessAcceso abierto2021LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.unbosque.edu.co/bitstreams/8cc417ea-7235-47da-8553-35874df0c7e6/download8a4605be74aa9ea9d79846c1fba20a33MD52ORIGINALMoutran_Barroso_Habib_2021.pdfMoutran_Barroso_Habib_2021.pdfapplication/pdf1604797https://repositorio.unbosque.edu.co/bitstreams/56cef96c-2c65-4266-8545-f19e45a0da06/download0e7e8107f74d8fd4266906b2d65aea3fMD51THUMBNAILMoutran_Barroso_Habib_2021.pdf.jpgMoutran_Barroso_Habib_2021.pdf.jpgimage/jpeg5775https://repositorio.unbosque.edu.co/bitstreams/ef28a97d-9f0a-4f58-ada9-20676c187ec4/download7210a811635d1799e7c05fee5d259be7MD53TEXTMoutran_Barroso_Habib_2021.pdf.txtMoutran_Barroso_Habib_2021.pdf.txtExtracted texttext/plain33106https://repositorio.unbosque.edu.co/bitstreams/787dfc9e-649f-47f4-b4ee-a9c45c4c23ad/downloadc9ba06a6de9d625a69cd12f0f4e39a3fMD5420.500.12495/5553oai:repositorio.unbosque.edu.co:20.500.12495/55532024-02-07 00:57:36.394restrictedhttps://repositorio.unbosque.edu.coRepositorio Institucional Universidad El Bosquebibliotecas@biteca.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