Modelling the dynamics of antibody production in birds

This paper presents a dynamical model of avian immune response, for antibody production purposes. Antibodies are fundamental tools for research, diagnosis, and the treatment of several diseases. It has been recognized for some time that antibodies obtained from poultry are an efficient alternative f...

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Autores:
Olarte Dussan, Fredy Andres
Clavijo Ramirez, Carlos Arturo
Díaz Morales, Hernando
Tipo de recurso:
Article of journal
Fecha de publicación:
2011
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/37751
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/37751
http://bdigital.unal.edu.co/27835/
Palabra clave:
Avian immunology
antibodies
dynamical models.
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
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spelling Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Olarte Dussan, Fredy Andres02727e74-7ac0-4477-af6b-a65e3b470f1d300Clavijo Ramirez, Carlos Arturo5759a9ff-77a7-46c2-9102-c77e024e969b300Díaz Morales, Hernando5e557bf7-0222-4755-9228-ba041cbe41933002019-06-28T01:58:41Z2019-06-28T01:58:41Z2011https://repositorio.unal.edu.co/handle/unal/37751http://bdigital.unal.edu.co/27835/This paper presents a dynamical model of avian immune response, for antibody production purposes. Antibodies are fundamental tools for research, diagnosis, and the treatment of several diseases. It has been recognized for some time that antibodies obtained from poultry are an efficient alternative for applications in medicine and biology. Therefore, a dynamical model for this process might be very useful. The model being proposed consists of seven non-linear ordinary differential equations with constant coefficients that represent the main cellular and molecular populations in avian immune response. Values for the parameters were obtained from avian and mammalian literature. In silico-generated responses in terms of antibody concentrations are presented and compared to reported kinetics.application/pdfspaUniversidad Nacional de Colombia Sede Medellínhttp://revistas.unal.edu.co/index.php/dyna/article/view/25730Universidad Nacional de Colombia Revistas electrónicas UN DynaDynaDyna; Vol. 78, núm. 166 (2011); 174-182 DYNA; Vol. 78, núm. 166 (2011); 174-182 2346-2183 0012-7353Olarte Dussan, Fredy Andres and Clavijo Ramirez, Carlos Arturo and Díaz Morales, Hernando (2011) Modelling the dynamics of antibody production in birds. Dyna; Vol. 78, núm. 166 (2011); 174-182 DYNA; Vol. 78, núm. 166 (2011); 174-182 2346-2183 0012-7353 .Modelling the dynamics of antibody production in birdsArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTAvian immunologyantibodiesdynamical models.ORIGINAL25730-90219-1-PB.pdfapplication/pdf245237https://repositorio.unal.edu.co/bitstream/unal/37751/1/25730-90219-1-PB.pdf80941a8df213c61f907d10d3a9912237MD5125730-162433-1-PB.htmltext/html48884https://repositorio.unal.edu.co/bitstream/unal/37751/2/25730-162433-1-PB.html91d164e1ea524882982b613e22adb20eMD52THUMBNAIL25730-90219-1-PB.pdf.jpg25730-90219-1-PB.pdf.jpgGenerated Thumbnailimage/jpeg9456https://repositorio.unal.edu.co/bitstream/unal/37751/3/25730-90219-1-PB.pdf.jpgde41e6676b2b1120f6c868708ba5bbc7MD53unal/37751oai:repositorio.unal.edu.co:unal/377512024-01-12 23:05:57.638Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co
dc.title.spa.fl_str_mv Modelling the dynamics of antibody production in birds
title Modelling the dynamics of antibody production in birds
spellingShingle Modelling the dynamics of antibody production in birds
Avian immunology
antibodies
dynamical models.
title_short Modelling the dynamics of antibody production in birds
title_full Modelling the dynamics of antibody production in birds
title_fullStr Modelling the dynamics of antibody production in birds
title_full_unstemmed Modelling the dynamics of antibody production in birds
title_sort Modelling the dynamics of antibody production in birds
dc.creator.fl_str_mv Olarte Dussan, Fredy Andres
Clavijo Ramirez, Carlos Arturo
Díaz Morales, Hernando
dc.contributor.author.spa.fl_str_mv Olarte Dussan, Fredy Andres
Clavijo Ramirez, Carlos Arturo
Díaz Morales, Hernando
dc.subject.proposal.spa.fl_str_mv Avian immunology
antibodies
dynamical models.
topic Avian immunology
antibodies
dynamical models.
description This paper presents a dynamical model of avian immune response, for antibody production purposes. Antibodies are fundamental tools for research, diagnosis, and the treatment of several diseases. It has been recognized for some time that antibodies obtained from poultry are an efficient alternative for applications in medicine and biology. Therefore, a dynamical model for this process might be very useful. The model being proposed consists of seven non-linear ordinary differential equations with constant coefficients that represent the main cellular and molecular populations in avian immune response. Values for the parameters were obtained from avian and mammalian literature. In silico-generated responses in terms of antibody concentrations are presented and compared to reported kinetics.
publishDate 2011
dc.date.issued.spa.fl_str_mv 2011
dc.date.accessioned.spa.fl_str_mv 2019-06-28T01:58:41Z
dc.date.available.spa.fl_str_mv 2019-06-28T01:58:41Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.eprints.spa.fl_str_mv http://bdigital.unal.edu.co/27835/
url https://repositorio.unal.edu.co/handle/unal/37751
http://bdigital.unal.edu.co/27835/
dc.language.iso.spa.fl_str_mv spa
language spa
dc.relation.spa.fl_str_mv http://revistas.unal.edu.co/index.php/dyna/article/view/25730
dc.relation.ispartof.spa.fl_str_mv Universidad Nacional de Colombia Revistas electrónicas UN Dyna
Dyna
dc.relation.ispartofseries.none.fl_str_mv Dyna; Vol. 78, núm. 166 (2011); 174-182 DYNA; Vol. 78, núm. 166 (2011); 174-182 2346-2183 0012-7353
dc.relation.references.spa.fl_str_mv Olarte Dussan, Fredy Andres and Clavijo Ramirez, Carlos Arturo and Díaz Morales, Hernando (2011) Modelling the dynamics of antibody production in birds. Dyna; Vol. 78, núm. 166 (2011); 174-182 DYNA; Vol. 78, núm. 166 (2011); 174-182 2346-2183 0012-7353 .
dc.rights.spa.fl_str_mv Derechos reservados - Universidad Nacional de Colombia
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional
dc.rights.uri.spa.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv Atribución-NoComercial 4.0 Internacional
Derechos reservados - Universidad Nacional de Colombia
http://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Universidad Nacional de Colombia Sede Medellín
institution Universidad Nacional de Colombia
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