Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications
The aim of this research was to develop membranes of polyvinyl alcohol (PVA) and chitosan (CH), capable of absorbing an Aloe Vera solution and gradually releasing to accelerate wound healing. The methodology involved varying the membrane’s composition using Chitosan and Polyvinyl Alcohol at 5 and 10...
- Autores:
-
Escobar-Sierra, Diana Marcela
Perea-Mesa, Yuli Paola
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2017
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/60861
- Acceso en línea:
- https://repositorio.unal.edu.co/handle/unal/60861
http://bdigital.unal.edu.co/59243/
- Palabra clave:
- 62 Ingeniería y operaciones afines / Engineering
Aloe Vera
Chitosan
Hydrogel
Mechanical Strength
Polyvinyl Alcohol
Aloe Vera
Quitosano
Hidrogel
Resistencia Mecánica
Alcohol PoliVinilico
- Rights
- openAccess
- License
- Atribución-NoComercial 4.0 Internacional
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| dc.title.spa.fl_str_mv |
Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications |
| title |
Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications |
| spellingShingle |
Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications 62 Ingeniería y operaciones afines / Engineering Aloe Vera Chitosan Hydrogel Mechanical Strength Polyvinyl Alcohol Aloe Vera Quitosano Hidrogel Resistencia Mecánica Alcohol PoliVinilico |
| title_short |
Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications |
| title_full |
Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications |
| title_fullStr |
Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications |
| title_full_unstemmed |
Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications |
| title_sort |
Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications |
| dc.creator.fl_str_mv |
Escobar-Sierra, Diana Marcela Perea-Mesa, Yuli Paola |
| dc.contributor.author.spa.fl_str_mv |
Escobar-Sierra, Diana Marcela Perea-Mesa, Yuli Paola |
| dc.subject.ddc.spa.fl_str_mv |
62 Ingeniería y operaciones afines / Engineering |
| topic |
62 Ingeniería y operaciones afines / Engineering Aloe Vera Chitosan Hydrogel Mechanical Strength Polyvinyl Alcohol Aloe Vera Quitosano Hidrogel Resistencia Mecánica Alcohol PoliVinilico |
| dc.subject.proposal.spa.fl_str_mv |
Aloe Vera Chitosan Hydrogel Mechanical Strength Polyvinyl Alcohol Aloe Vera Quitosano Hidrogel Resistencia Mecánica Alcohol PoliVinilico |
| description |
The aim of this research was to develop membranes of polyvinyl alcohol (PVA) and chitosan (CH), capable of absorbing an Aloe Vera solution and gradually releasing to accelerate wound healing. The methodology involved varying the membrane’s composition using Chitosan and Polyvinyl Alcohol at 5 and 10% w/v, and implementing different PVA/CH relations of 30/70, 50/50 and 70/30 (v/v) and embed them in a 2% (v/v) Aloe Vera solution to create hydrogels. Once hydrogels were obtained, they were characterized by Infrared Spectroscopy and Scanning Electronic Microscopy, and evaluated by mechanical and absorption tests as well as bactericide activity assays.The crosslinking degree between PVA/CH allowed obtaining a matrix with high absorption capacity and with gradual release of Aloe Vera, with mechanical properties and dimensional stability even after rehydration. Bactericide assays showed chitosan and Aloe Vera protective activity, which indicates this compound may be suitable for applications that help in wound healing. |
| publishDate |
2017 |
| dc.date.issued.spa.fl_str_mv |
2017-10-01 |
| dc.date.accessioned.spa.fl_str_mv |
2019-07-02T19:18:06Z |
| dc.date.available.spa.fl_str_mv |
2019-07-02T19:18:06Z |
| dc.type.spa.fl_str_mv |
Artículo de revista |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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info:eu-repo/semantics/article |
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info:eu-repo/semantics/publishedVersion |
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http://purl.org/coar/resource_type/c_6501 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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Text |
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http://purl.org/redcol/resource_type/ART |
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http://purl.org/coar/resource_type/c_6501 |
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publishedVersion |
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ISSN: 2346-2183 |
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https://repositorio.unal.edu.co/handle/unal/60861 |
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http://bdigital.unal.edu.co/59243/ |
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ISSN: 2346-2183 |
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https://repositorio.unal.edu.co/handle/unal/60861 http://bdigital.unal.edu.co/59243/ |
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spa |
| language |
spa |
| dc.relation.spa.fl_str_mv |
https://revistas.unal.edu.co/index.php/dyna/article/view/62742 |
| dc.relation.ispartof.spa.fl_str_mv |
Universidad Nacional de Colombia Revistas electrónicas UN Dyna Dyna |
| dc.relation.references.spa.fl_str_mv |
Escobar-Sierra, Diana Marcela and Perea-Mesa, Yuli Paola (2017) Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications. DYNA, 84 (203). pp. 134-142. ISSN 2346-2183 |
| dc.rights.spa.fl_str_mv |
Derechos reservados - Universidad Nacional de Colombia |
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http://purl.org/coar/access_right/c_abf2 |
| dc.rights.license.spa.fl_str_mv |
Atribución-NoComercial 4.0 Internacional |
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http://creativecommons.org/licenses/by-nc/4.0/ |
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info:eu-repo/semantics/openAccess |
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Atribución-NoComercial 4.0 Internacional Derechos reservados - Universidad Nacional de Colombia http://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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Universidad Nacional de Colombia (Sede Medellín). Facultad de Minas. |
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Universidad Nacional de Colombia |
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Atribución-NoComercial 4.0 InternacionalDerechos reservados - Universidad Nacional de Colombiahttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Escobar-Sierra, Diana Marcelab959e01f-7559-47ad-8abf-dc8afee5fcd8300Perea-Mesa, Yuli Paola944ff8fe-fc36-4af2-b756-cc35597250d03002019-07-02T19:18:06Z2019-07-02T19:18:06Z2017-10-01ISSN: 2346-2183https://repositorio.unal.edu.co/handle/unal/60861http://bdigital.unal.edu.co/59243/The aim of this research was to develop membranes of polyvinyl alcohol (PVA) and chitosan (CH), capable of absorbing an Aloe Vera solution and gradually releasing to accelerate wound healing. The methodology involved varying the membrane’s composition using Chitosan and Polyvinyl Alcohol at 5 and 10% w/v, and implementing different PVA/CH relations of 30/70, 50/50 and 70/30 (v/v) and embed them in a 2% (v/v) Aloe Vera solution to create hydrogels. Once hydrogels were obtained, they were characterized by Infrared Spectroscopy and Scanning Electronic Microscopy, and evaluated by mechanical and absorption tests as well as bactericide activity assays.The crosslinking degree between PVA/CH allowed obtaining a matrix with high absorption capacity and with gradual release of Aloe Vera, with mechanical properties and dimensional stability even after rehydration. Bactericide assays showed chitosan and Aloe Vera protective activity, which indicates this compound may be suitable for applications that help in wound healing.El objetivo fue desarrollar membranas de Polivinil Alcohol (PVA) y Quitosano (Qo), capaces de absorber solución de Aloe Vera y luego liberarla gradualmente para acelerar la cicatrización de la herida. La metodología empleada consistió en variar la composición de las membranas usando quitosano y Polivinil Alcohol al 5 y 10% p/v, e implementar diferentes relaciones de PVA/Qo de 30/70, 50/50 y 70/30 (v/v), para posteriormente embeberlas en solución de Aloe Vera al 2% (v/v) y formar hidrogeles. Una vez obtenidos, éstos fueron caracterizados por Espectroscopía de Infrarrojo y Microscopía Electrónica de Barrido, y evaluadas por pruebas mecánicas, pruebas de absorción, y ensayos de actividad bactericida.El grado de entrecruzamiento entre el PVA y el Quitosano permitió obtener una matriz con alta capacidad de absorción y liberación controlada de Aloe Vera, con propiedades mecánicas y estabilidad dimensional aún después de rehidratadas. Las pruebas bactericidas mostraron actividad protectora del quitosano y del Aloe Vera, lo cual hace que este compuesto sea adecuado para aplicaciones que ayudan en la curación de heridas.application/pdfspaUniversidad Nacional de Colombia (Sede Medellín). Facultad de Minas.https://revistas.unal.edu.co/index.php/dyna/article/view/62742Universidad Nacional de Colombia Revistas electrónicas UN DynaDynaEscobar-Sierra, Diana Marcela and Perea-Mesa, Yuli Paola (2017) Manufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applications. DYNA, 84 (203). pp. 134-142. ISSN 2346-218362 Ingeniería y operaciones afines / EngineeringAloe VeraChitosanHydrogelMechanical StrengthPolyvinyl AlcoholAloe VeraQuitosanoHidrogelResistencia MecánicaAlcohol PoliVinilicoManufacturing and evaluation of Chitosan, PVA and Aloe Vera hydrogels for skin applicationsArtículo de revistainfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/ARTORIGINAL62742-357509-1-PB.pdfapplication/pdf1314561https://repositorio.unal.edu.co/bitstream/unal/60861/1/62742-357509-1-PB.pdfd0190b918b4525340bd2fbfc4d654fedMD51THUMBNAIL62742-357509-1-PB.pdf.jpg62742-357509-1-PB.pdf.jpgGenerated Thumbnailimage/jpeg9600https://repositorio.unal.edu.co/bitstream/unal/60861/2/62742-357509-1-PB.pdf.jpgc7d54538e1beb2a390beb8b232a69ad3MD52unal/60861oai:repositorio.unal.edu.co:unal/608612024-04-15 23:09:05.945Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.co |