Caracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia.
ilustraciones, fotografías, mapas
- Autores:
-
Coronel Guzmán, María Alejandra
- Tipo de recurso:
- Fecha de publicación:
- 2023
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/85257
- Palabra clave:
- 570 - Biología::576 - Genética y evolución
Huesos
Antropología
Bone and Bones
Anthropology
Physiology
Fisiología
Poblaciones prehispánicas, ADNmt, ADN antiguo, Valle del Magdalena, restos óseos, poblamiento americano
Poblaciones prehispánicas
ADNmt
ADN antiguo
Valle del Magdalena
Restos óseos
Poblamiento americano
- Rights
- openAccess
- License
- Reconocimiento 4.0 Internacional
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| dc.title.spa.fl_str_mv |
Caracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia. |
| dc.title.translated.eng.fl_str_mv |
Phylogenetic characterization of mitochondrial DNA (mtDNA) of bone remains from 5 pre-Columbian populations from Bajo Magdalena, Colombia. |
| title |
Caracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia. |
| spellingShingle |
Caracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia. 570 - Biología::576 - Genética y evolución Huesos Antropología Bone and Bones Anthropology Physiology Fisiología Poblaciones prehispánicas, ADNmt, ADN antiguo, Valle del Magdalena, restos óseos, poblamiento americano Poblaciones prehispánicas ADNmt ADN antiguo Valle del Magdalena Restos óseos Poblamiento americano |
| title_short |
Caracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia. |
| title_full |
Caracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia. |
| title_fullStr |
Caracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia. |
| title_full_unstemmed |
Caracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia. |
| title_sort |
Caracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia. |
| dc.creator.fl_str_mv |
Coronel Guzmán, María Alejandra |
| dc.contributor.advisor.none.fl_str_mv |
Casas Vargas, Lilian Andrea Usaquén Martínez, William |
| dc.contributor.author.none.fl_str_mv |
Coronel Guzmán, María Alejandra |
| dc.contributor.educationalvalidator.none.fl_str_mv |
Rodríguez Cuenca, José Vicente |
| dc.contributor.researchgroup.spa.fl_str_mv |
Grupo de Investigación en Antropología Biológica (Giab) Genética de Poblaciones e Identificación |
| dc.contributor.orcid.spa.fl_str_mv |
Coronel Guzmán, María Alejandra [https://orcid.org/0009-0007-1365-9647] |
| dc.contributor.cvlac.spa.fl_str_mv |
https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000133153 |
| dc.subject.ddc.spa.fl_str_mv |
570 - Biología::576 - Genética y evolución |
| topic |
570 - Biología::576 - Genética y evolución Huesos Antropología Bone and Bones Anthropology Physiology Fisiología Poblaciones prehispánicas, ADNmt, ADN antiguo, Valle del Magdalena, restos óseos, poblamiento americano Poblaciones prehispánicas ADNmt ADN antiguo Valle del Magdalena Restos óseos Poblamiento americano |
| dc.subject.decs.spa.fl_str_mv |
Huesos Antropología |
| dc.subject.decs.eng.fl_str_mv |
Bone and Bones |
| dc.subject.decs.none.fl_str_mv |
Anthropology |
| dc.subject.lemb.eng.fl_str_mv |
Physiology |
| dc.subject.lemb.spa.fl_str_mv |
Fisiología |
| dc.subject.proposal.none.fl_str_mv |
Poblaciones prehispánicas, ADNmt, ADN antiguo, Valle del Magdalena, restos óseos, poblamiento americano |
| dc.subject.proposal.spa.fl_str_mv |
Poblaciones prehispánicas ADNmt ADN antiguo Valle del Magdalena Restos óseos Poblamiento americano |
| description |
ilustraciones, fotografías, mapas |
| publishDate |
2023 |
| dc.date.issued.none.fl_str_mv |
2023-11-24 |
| dc.date.accessioned.none.fl_str_mv |
2024-01-12T20:04:34Z |
| dc.date.available.none.fl_str_mv |
2024-01-12T20:04:34Z |
| dc.type.spa.fl_str_mv |
Trabajo de grado - Maestría |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/masterThesis |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
| dc.type.content.spa.fl_str_mv |
Collection DataPaper Dataset Text |
| dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/TM |
| status_str |
acceptedVersion |
| dc.identifier.uri.none.fl_str_mv |
https://repositorio.unal.edu.co/handle/unal/85257 |
| dc.identifier.instname.spa.fl_str_mv |
Universidad Nacional de Colombia |
| dc.identifier.reponame.spa.fl_str_mv |
Repositorio Institucional Universidad Nacional de Colombia |
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https://repositorio.unal.edu.co/ |
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https://repositorio.unal.edu.co/handle/unal/85257 https://repositorio.unal.edu.co/ |
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Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
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spa |
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spa |
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Achilli, A., Perego, U. A., Bravi, C. M., Coble, M. D., Kong, Q. P., Woodward, S. R., Salas, A., Torroni, A., & Bandelt, H. J. (2008). The phylogeny of the four pan-American MtDNA haplogroups: Implications for evolutionary and disease studies. PLoS ONE, 3(3). https://doi.org/10.1371/journal.pone.0001764 Bodner, M., Perego, U. A., Huber, G., Fendt, L., Röck, A. W., Zimmermann, B., Olivieri, A., Gómez-Carballa, A., Lancioni, H., Angerhofer, N., Bobillo, M. C., Corach, D., Woodward, S. R., Salas, A., Achilli, A., Torroni, A., Bandelt, H.-J., & Parson, W. (2012). Rapid coastal spread of First Americans: novel insights from South America’s Southern Cone mitochondrial genomes. Genome Research, 22(5), 811–820. https://doi.org/10.1101/gr.131722.111 Capodiferro, M. R., Aram, B., Raveane, A., Rambaldi Migliore, N., Colombo, G., Ongaro, L., Rivera, J., Mendizábal, T., Hernández-Mora, I., Tribaldos, M., Perego, U. A., Li, H., Scheib, C. L., Modi, A., Gòmez-Carballa, A., Grugni, V., Lombardo, G., Hellenthal, G., Pascale, J. M., … Achilli, A. (2021). Archaeogenomic distinctiveness of the Isthmo-Colombian area. Cell, 184(7), 1706-1723.e24. https://doi.org/10.1016/j.cell.2021.02.040 De Saint Pierre, M., Bravi, C. M., Motti, J. M. B., Fuku, N., Tanaka, M., Llop, E., Bonatto, S. L., & Moraga, M. (2012). An alternative model for the early peopling of Southern South America revealed by analyses of three mitochondrial DNA haplogroups. PLoS ONE, 7(9). https://doi.org/10.1371/journal.pone.0043486 de Saint Pierre, M., Gandini, F., Perego, U. A., Bodner, M., Gómez-Carballa, A., Corach, D., Angerhofer, N., Woodward, S. R., Semino, O., Salas, A., Parson, W., Moraga, M., Achilli, A., Torroni, A., & Olivieri, A. (2012). Arrival of Paleo-Indians to the Southern Cone of South America: New Clues from Mitogenomes. PLoS ONE, 7(12), 1–9. https://doi.org/10.1371/journal.pone.0051311 Díaz-Matallana, M., Gómez Gutiérrez, A., Briceño, I., & Rodríguez Cuenca, J. V. (2016). Genetic analysis of paleo-colombians from Nemocón, Cundinamarca provides insights on the early peopling of northwestern South America. Revista de La Academia Colombiana de Ciencias Exactas, Físicas y Naturales, 40(156), 461. https://doi.org/10.18257/raccefyn.328 Dillehay, T. D., Ocampo, C., Saavedra, J., Sawakuchi, A. O., Vega, R. M., Pino, M., Collins, M. B., Cummings, L. S., Arregui, I., Villagran, X. S., Hartmann, G. A., Mella, M., González, A., & Dix, G. (2015). New archaeological evidence for an early human presence at Monte Verde, Chile. PLoS ONE, 10(11), 1–27. https://doi.org/10.1371/journal.pone.0141923 Fagundes, N. J. R., Kanitz, R., Eckert, R., Valls, A. C. S., Bogo, M. R., Salzano, F. M., Smith, D. G., Silva, W. A. J., Zago, M. A., Ribeiro-dos-Santos, A. K., Santos, S. E. B., Petzl-Erler, M. L., & Bonatto, S. L. (2008). 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Chungara, 43(2), 283–292. https://doi.org/10.4067/S0717-73562011000200009 Martínez, B., Simão, F., Gomes, V., Nguidi, M., Amorim, A., Carvalho, E. F., Marrugo, J., & Gusmão, L. (2020). Searching for the roots of the first free African American community. Scientific Reports, 10(1), 1–11. https://doi.org/10.1038/s41598-020-77608-8 Melton, P. E., Baldi, N. F., Barrantes, R., & Crawford, M. H. (2013). Microevolution, migration, and the population structure of five Amerindian populations from Nicaragua and Costa Rica. American Journal of Human Biology : The Official Journal of the Human Biology Council, 25(4), 480–490. https://doi.org/10.1002/ajhb.22382 Messina, F., Corcia, T. Di, Ragazzo, M., Mellado, C. S., Contini, I., Malaspina, P., Ciminelli, B. M., Rickards, O., & Jodice, C. (2018). Signs of continental ancestry in urban populations of Peru through autosomal STR loci and mitochondrial DNA typing. PLoS ONE, 13(7), 1–18. https://doi.org/10.1371/journal.pone.0200796 Perego, U. A., Achilli, A., Angerhofer, N., Accetturo, M., Pala, M., Olivieri, A., Kashani, B. H., Ritchie, K. H., Scozzari, R., Kong, Q. P., Myres, N. M., Salas, A., Semino, O., Bandelt, H. J., Woodward, S. R., & Torroni, A. (2009). Distinctive Paleo-Indian Migration Routes from Beringia Marked by Two Rare mtDNA Haplogroups. Current Biology, 19(1), 1–8. https://doi.org/10.1016/j.cub.2008.11.058 Perego, U. A., Lancioni, H., Tribaldos, M., Angerhofer, N., Ekins, J. E., Olivieri, A., Woodward, S. R., Pascale, J. M., Cooke, R., Motta, J., & Achilli, A. (2012). Decrypting the mitochondrial gene pool of modern panamanians. PLoS ONE, 7(6). https://doi.org/10.1371/journal.pone.0038337 Reichel-Dolmatoff, G. (2016). Arqueología de Colombia: un texto introductorio. In Biblioteca Virtual del Banco de la República. Rodríguez, J. V., Cifuentes, A., & Cabal, G. (2012). Arqueología en el “valle de la Tristura,” sur del Alto Magdalena, Huila. 327. Rohland, N., Glocke, I., Aximu-Petri, A., & Meyer, M. (2018). Extraction of highly degraded DNA from ancient bones, teeth and sediments for high-throughput sequencing. Nature Protocols, 13(11), 2447–2461. https://doi.org/10.1038/s41596-018-0050-5 Simão, F., Ferreira, A. P., de Carvalho, E. F., Parson, W., & Gusmão, L. (2018). Defining mtDNA origins and population stratification in Rio de Janeiro. Forensic Science International: Genetics, 34(December 2017), 97–104. https://doi.org/10.1016/j.fsigen.2018.02.003 Tamm, E., Kivisild, T., Reidla, M., Metspalu, M., Smith, D. G., Mulligan, C. J., Bravi, C. M., Rickards, O., Martinez-Labarga, C., Khusnutdinova, E. K., Fedorova, S. A., Golubenko, M. V., Stepanov, V. A., Gubina, M. A., Zhadanov, S. I., Ossipova, L. P., Damba, L., Voevoda, M. I., Dipierri, J. E., … Malhi, R. S. (2007). Beringian standstill and spread of native American founders. PLoS ONE, 2(9). https://doi.org/10.1371/journal.pone.0000829 Van Oven, M., & Kayser, M. (2009). Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Human Mutation, 30(2), 386–394. https://doi.org/10.1002/humu.20921 Wang, S., Lewis, C. M., Jakobsson, M., Ramachandran, S., Ray, N., Bedoya, G., Rojas, W., Parra, M. V., Molina, J. A., Gallo, C., Mazzotti, G., Poletti, G., Hill, K., Hurtado, A. M., Labuda, D., Klitz, W., Barrantes, R., Bortolini, M. C., Salzano, F. M., … Ruiz-Linares, A. (2007). Genetic variation and population structure in Native Americans. PLoS Genetics, 3(11), 2049–2067. https://doi.org/10.1371/journal.pgen.0030185 Xavier, C., Builes, J. J., Gomes, V., Ospino, J. M., Aquino, J., Parson, W., Amorim, A., Gusmão, L., & Goios, A. (2015). Admixture and genetic diversity distribution patterns of non-recombining lineages of native american ancestry in colombian populations. PLoS ONE, 10(3), 1–13. https://doi.org/10.1371/journal.pone.0120155 Arias, L., Barbieri, C., & Barreto, G. (2017). 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Sinopsis de la arqueología y la bioantropología del poblamiento temprano del noroccidente de Sudamérica. Revista Colombiana de Antropología, 53(1), 213–239. https://doi.org/10.22380/2539472x.9 Gómez-Carballa, A., Ignacio-Veiga, A., Álvarez-Iglesias, V., Pastoriza-Mourelle, A., Ruíz, Y., Pineda, L., Carracedo, Á., & Salas, A. (2012). A melting pot of multicontinental mtDNA lineages in admixed Venezuelans. American Journal of Physical Anthropology, 147(1), 78–87. https://doi.org/https://doi.org/10.1002/ajpa.21629 Kumar, S., Bellis, C., Zlojutro, M., Melton, P. E., Blangero, J., & Curran, J. E. (2011). Large scale mitochondrial sequencing in Mexican Americans suggests a reappraisal of Native American origins. BMC Evolutionary Biology, 11(1), 293. https://doi.org/10.1186/1471-2148-11-293 Morales-Arce, A. Y., Hofman, C. A., Duggan, A. T., Benfer, A. K., Katzenberg, M. A., McCafferty, G., & Warinner, C. (2017). Successful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico. Scientific Reports, 7(1), 1–13. https://doi.org/10.1038/s41598-017-18356-0 Noguera-Santamaría, M. C., Rivera-Sandoval, J., Martín, J. G., Briceño-Balcázar, I., & Gómez-Gutiérrez, A. (2020). Genetic analysis of pre-columbian human remains from lower magdalena suggests a migratory route and matrilineal genetic continuity in Northern South America. Revista de La Academia Colombiana de Ciencias Exactas, Fisicas y Naturales, 44(172), 704–715. https://doi.org/10.18257/RACCEFYN.973 Patrícia, B., & Ribeiro, A. (2021). Genetic characterization of the maternal lineages in Andean Colombian populations. Rieux, A., Eriksson, A., Li, M., Sobkowiak, B., Weinert, L. A., Warmuth, V., Ruiz-Linares, A., Manica, A., & Balloux, F. (2014). Improved calibration of the human mitochondrial clock using ancient genomes. Molecular Biology and Evolution, 31(10), 2780–2792. https://doi.org/10.1093/molbev/msu222 Scorrano, G., Viva, S., Pinotti, T., Fabbri, P. F., Rickards, O., & Macciardi, F. (2022). Bioarchaeological and palaeogenomic portrait of two Pompeians that died during the eruption of Vesuvius in 79 AD. Scientific Reports, 12(1), 6468. https://doi.org/10.1038/s41598-022-10899- Tamm, E., Kivisild, T., Reidla, M., Metspalu, M., Smith, D. G., Mulligan, C. J., Bravi, C. M., Rickards, O., Martinez-Labarga, C., Khusnutdinova, E. K., Fedorova, S. A., Golubenko, M. V., Stepanov, V. A., Gubina, M. A., Zhadanov, S. I., Ossipova, L. P., Damba, L., Voevoda, M. I., Dipierri, J. E., … Malhi, R. S. (2007). Beringian standstill and spread of native American founders. PLoS ONE, 2(9). https://doi.org/10.1371/journal.pone.0000829 Zheng, H. X., Yan, S., Qin, Z. D., & Jin, L. (2012). MtDNA analysis of global populations support that major population expansions began before Neolithic Time. Scientific Reports, 2. https://doi.org/10.1038/srep00745 Tovar, G. M. de. (1993). Poblamiento y sociedad en el bajo magdalena durante la segunda mitad del siglo XVIII. Anuario Colombiano de Historia Social y de La Cultura, 0(21), 40–62. |
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Reconocimiento 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Casas Vargas, Lilian Andrea36bbd2323102900ba533a371322653adUsaquén Martínez, William4ef7bc5fd4f471346296f0c6a4b91c64Coronel Guzmán, María Alejandra1ac47e863dba7428c8d397a4edb6d245Rodríguez Cuenca, José VicenteGrupo de Investigación en Antropología Biológica (Giab)Genética de Poblaciones e IdentificaciónCoronel Guzmán, María Alejandra [https://orcid.org/0009-0007-1365-9647]https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=00001331532024-01-12T20:04:34Z2024-01-12T20:04:34Z2023-11-24https://repositorio.unal.edu.co/handle/unal/85257Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, fotografías, mapasLos estudios arqueogenómicos indican que el poblamiento de América sucedió hace aproximadamente 16.000 años antes del presente. Adicionalmente, Colombia fue un punto importante de entrada al continente suramericano, y cuenta con limitados estudios que describen su historia genético-poblacional. Las comunidades precolombinas del valle del río Magdalena son de interés a nivel de ADN antiguo, ya que, por su posición geográfica contribuyeron al desarrollo de procesos bioculturales y adaptativos que llevaron a migraciones, relaciones interpoblacionales, diversificación biológica y la colonización hasta el sur del continente. El objetivo de este estudio es analizar la estructura genética por vía matrilineal de restos óseos del valle del río Magdalena a través del análisis de la región control y genomas completos de ADN mitocondrial. Se obtuvieron datos de la región control en 11 muestras y 15 genomas mitocondriales de restos óseos precolombinos de la cuenca del río Magdalena, realizando posteriormente, asignación de haplogrupos mitocondriales, diversidad genética, filogenia matrilineal, y su relación entre los haplotipos encontrados a nivel inter e intrapoblacional, a través de los softwares Arlequín, Network y mtPhyl. Los linajes del ADNmt observados en este grupo poblacional pertenecen a los haplogrupos nativoamericanos A, B, C y D, se lograron definir 9 subhaplogrupos que están relacionados con otras poblaciones antiguas y contemporáneas de América o que, en otros casos, se encuentran aislados y restringidos a poblaciones colombianas y sus zonas fronterizas, las cuales revelan relaciones intra e interpoblacionales y sucesos de contacto importantes. En conclusión, este reporte de genomas mitocondriales precolombinos del Magdalena complementa las hipótesis arqueológicas del poblamiento suramericano, de los movimientos migracionales, de la diversidad genética y de la historia cultural de estas poblaciones evidenciando linajes fundadores y que se encuentran estrechamente ligados por línea materna con una alta diversidad genética. (Texto tomado de la fuente)Archaeogenomic studies indicate that the peopling of America occurred approximately 16,000 years ago before the present. Furthermore, Colombia was an important entry point to the South American continent, and has limited studies that describe its genetic-population history. The pre-Columbian communities of the Magdalena River Valley are of interest at the level of ancient DNA, since, due to their geographical position, they contributed to the development of biocultural and adaptive processes that led to migrations, interpopulation relationships, biological diversification and colonization to the south of the continent. The aim of this study is to analyze the genetic structure through the matrilineal phylogeny of human skeletons from the Magdalena River Valley through the analysis of the control region and complete mitochondrial DNA genomes. Data from the control region were obtained in 11 samples and 15 mitochondrial genomes from pre-Columbian dental samples from the Magdalena River Valley, subsequently assigning mitochondrial haplogroups, genetic diversity, matrilineal phylogeny, and their relationship between the haplotypes found at the inter- and intrapopulation, through the Arlequín, Network and mtPhyl software. The mtDNA lineages observed in this population belong to the Native American haplogroups A, B, C and D, it was possible to define 9 subhaplogroups that are related to other ancient and contemporary populations of America and others, are isolated and restricted to Colombian populations and their border areas, which reveal intra- and inter-population relationships and important contact events. In conclusion, this report of pre-Columbian mitochondrial genomes from Magdalena complements the archaeological hypotheses of the South American settlement, migratory movements, genetic diversity and cultural history of these populations, evidencing founding lineages that are closely linked by maternal lineage with a high genetic diversity.Código Registro: 71442 Título: Análisis Paleogenético y Paleoantropológico de los grupos prehispánicos de la cuenca del Río Magdalena Convocatoria: 852-2019 CONVOCATORIA DE PROYECTOS CONECTANDO CONOCIMIENTO 2019 Programa Nacional de CTeI: PROGRAMA NACIONAL EN CIENCIAS BÁSICAS Entidad/Persona: UNIVERSIDAD NACIONAL DE COLOMBIA - SEDE BOGOTÁ (OFICIAL) Tipo: Proyecto Tipo Financiación: RECUPERACIÓN CONTINGENTE Lugar Ejecución: BOGOTA D.C. Focos Estratégicos: CIENCIAS DE LA VIDA Temática(s): BIOLOGÍA EVOLUTIVAMaestríaMagíster en Genética HumanaInvestigación con datos propios en cooperación Antropología Física y Biológica y el grupo de Genética de Poblaciones e Identificación del Instituto de Genética de la Universidad Nacional de ColombiaPaleogenéticaADN antiguoGenética de poblaciones135 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Maestría en Genética HumanaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá570 - Biología::576 - Genética y evoluciónHuesosAntropologíaBone and BonesAnthropologyPhysiologyFisiologíaPoblaciones prehispánicas, ADNmt, ADN antiguo, Valle del Magdalena, restos óseos, poblamiento americanoPoblaciones prehispánicasADNmtADN antiguoValle del MagdalenaRestos óseosPoblamiento americanoCaracterización filogenética del ADN mitocondrial (ADNmt) de restos óseos provenientes de 5 poblaciones precolombinas del Bajo Magdalena, Colombia.Phylogenetic characterization of mitochondrial DNA (mtDNA) of bone remains from 5 pre-Columbian populations from Bajo Magdalena, Colombia.Trabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionCollectionDataPaperDatasetTexthttp://purl.org/redcol/resource_type/TMColombiaBajo MagdalenaAchilli, A., Perego, U. 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Anuario Colombiano de Historia Social y de La Cultura, 0(21), 40–62.Análisis Paleogenético y Paleoantropológico de los grupos prehispánicos de la cuenca del Río MagdalenaMinCienciasEstudiantesInvestigadoresMaestrosPersonal de apoyo escolarPúblico generalLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/85257/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINALTESIS MAESTRÍAGENÉTICAHUMANA_MACG_2023.pdfTESIS MAESTRÍAGENÉTICAHUMANA_MACG_2023.pdfTesis de Maestría en Genética Humanaapplication/pdf3441858https://repositorio.unal.edu.co/bitstream/unal/85257/2/TESIS%20MAESTR%c3%8dAGEN%c3%89TICAHUMANA_MACG_2023.pdfe2a81cd0ec3adfb42704616af7e8348dMD52THUMBNAILTESIS MAESTRÍAGENÉTICAHUMANA_MACG_2023.pdf.jpgTESIS MAESTRÍAGENÉTICAHUMANA_MACG_2023.pdf.jpgGenerated 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