Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico

ilustraciones, diagramas

Autores:: Espitia Porras, Laura Fernanda

Tipo de recurso:

Fecha de publicación:: 2023

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:

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repository_id_str
dc.title.spa.fl_str_mv	Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico
dc.title.translated.eng.fl_str_mv	Variation in plasma volumene as a confounding factor in the haematological biological passport
title	Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico
spellingShingle	Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico 610 - Medicina y salud::612 - Fisiología humana 790 - Deportes, juegos y entretenimiento::796 - Deportes y juegos al aire libre y deportivos Atletas Athletes Ciclistas Deportistas Cyclists Athletes Volumen plasmático Ejercicio Pasaporte Biológico del Atleta PBA Off-Score Plasma volume Exercise Biological Passport of Athlete BPA Off-Score
title_short	Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico
title_full	Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico
title_fullStr	Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico
title_full_unstemmed	Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico
title_sort	Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico
dc.creator.fl_str_mv	Espitia Porras, Laura Fernanda
dc.contributor.advisor.none.fl_str_mv	Cristancho Mejía, Edgar Mancera Soto, Erica
dc.contributor.author.none.fl_str_mv	Espitia Porras, Laura Fernanda
dc.contributor.researchgroup.spa.fl_str_mv	Grupo de Investigacion en Adaptaciones Al Ejercicio y A la Hipoxia
dc.subject.ddc.spa.fl_str_mv	610 - Medicina y salud::612 - Fisiología humana 790 - Deportes, juegos y entretenimiento::796 - Deportes y juegos al aire libre y deportivos
topic	610 - Medicina y salud::612 - Fisiología humana 790 - Deportes, juegos y entretenimiento::796 - Deportes y juegos al aire libre y deportivos Atletas Athletes Ciclistas Deportistas Cyclists Athletes Volumen plasmático Ejercicio Pasaporte Biológico del Atleta PBA Off-Score Plasma volume Exercise Biological Passport of Athlete BPA Off-Score
dc.subject.decs.spa.fl_str_mv	Atletas
dc.subject.decs.eng.fl_str_mv	Athletes
dc.subject.lemb.spa.fl_str_mv	Ciclistas Deportistas
dc.subject.lemb.eng.fl_str_mv	Cyclists Athletes
dc.subject.proposal.spa.fl_str_mv	Volumen plasmático Ejercicio Pasaporte Biológico del Atleta PBA Off-Score
dc.subject.proposal.eng.fl_str_mv	Plasma volume Exercise Biological Passport of Athlete BPA Off-Score
description	ilustraciones, diagramas
publishDate	2023
dc.date.accessioned.none.fl_str_mv	2023-08-28T14:53:09Z
dc.date.available.none.fl_str_mv	2023-08-28T14:53:09Z
dc.date.issued.none.fl_str_mv	2023
dc.type.spa.fl_str_mv	Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv	info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv	Text
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status_str	acceptedVersion
dc.identifier.uri.none.fl_str_mv	https://repositorio.unal.edu.co/handle/unal/84603
dc.identifier.instname.spa.fl_str_mv	Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv	https://repositorio.unal.edu.co/
url	https://repositorio.unal.edu.co/handle/unal/84603 https://repositorio.unal.edu.co/
identifier_str_mv	Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia
dc.relation.references.spa.fl_str_mv	Ashenden, M., Gough, C. E., Garnham, A., Gore, C. J., & Sharpe, K. (2011). Current markers of the Athlete Blood Passport do not flag microdose EPO doping. European Journal of Applied Physiology, 111(9), 2307-2314. https://doi.org/10.1007/s00421-011-1867-6 Astolfi, T., Crettaz von Roten, F., Kayser, B., Saugy, M., & Faiss, R. (2021). The Influence of Training Load on Hematological Athlete Biological Passport Variables in Elite Cyclists. Frontiers in Sports and Active Living, 3, 618285. https://doi.org/10.3389/fspor.2021.618285 Beidleman, B. A., Staab, J. E., Muza, S. R., & Sawka, M. N. (2017). Quantitative model of hematologic and plasma volume responses after ascent and acclimation to moderate to high altitudes. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 312(2), R265-R272. https://doi.org/10.1152/ajpregu.00225.2016 Bejder, J., Hoffmann, M. F., Ashenden, M., Nordsborg, N. B., Karstoft, K., & Mørkeberg, J. (2016). Acute hyperhydration reduces athlete biological passport OFF-hr score: Hyperhydration and athlete biological passport. Scandinavian Journal of Medicine & Science in Sports, 26(3), 338-347. https://doi.org/10.1111/sms.12438 Böning, D. (2019). Der kolumbianische Tour de France-Sieger Egan Bernal: Sportphysiologische Hintergründe. Deutsche Zeitschrift für Sportmedizin, 70(9), 195-196. https://doi.org/10.5960/dzsm.2019.397 Böning, D., Rojas, J., Serrato, M., Ulloa, C., Coy, L., Mora, M., Gomez, J., & Hütler, M. (2001). Hemoglobin mass and peak oxygen uptake in untrained and trained residents of moderate altitude. International Journal of Sports Medicine, 22(8), 572-578. https://doi.org/10.1055/s-2001-18530 Buchheit, M., Laursen, P. B., Al Haddad, H., & Ahmaidi, S. (2009). Exercise-induced plasma volume expansion and post-exercise parasympathetic reactivation. European Journal of Applied Physiology, 105(3), 471-481. https://doi.org/10.1007/s00421-008-0925-1 Burge, C. M., & Skinner, S. L. (1995). Determination of hemoglobin mass and blood volume with CO: Evaluation and application of a method. Journal of Applied Physiology (Bethesda, Md.: 1985), 79(2), 623-631. https://doi.org/10.1152/jappl.1995.79.2.623 Convertino, V. A. (2007). Blood Volume Response to Physical Activity and Inactivity. The American Journal of the Medical Sciences, 334(1), 72-79. https://doi.org/10.1097/MAJ.0b013e318063c6e4 Davis, J. A., Rozenek, R., DeCicco, D. M., Carizzi, M. T., & Pham, P. H. (2007). Effect of Plasma Volume Loss during Graded Exercise Testing on Blood Lactate Concentration. The Journal of Physiological Sciences, 57(2), 95-99. https://doi.org/10.2170/physiolsci.RP014406 Eichner, E. R. (1992). Sports anemia, iron supplements, and blood doping. Medicine and Science in Sports and Exercise, 24(9 Suppl), S315-318. Flouris, A. D., Poirier, M. P., Bravi, A., Wright-Beatty, H. E., Herry, C., Seely, A. J., & Kenny, G. P. (2014). Changes in heart rate variability during the induction and decay of heat acclimation. European Journal of Applied Physiology, 114(10), 2119-2128. https://doi.org/10.1007/s00421-014-2935-5 Fortney, S. M., Vroman, N. B., Beckett, W. S., Permutt, S., & LaFrance, N. D. (1988). Effect of exercise hemoconcentration and hyperosmolality on exercise responses. Journal of Applied Physiology, 65(2), 519-524. https://doi.org/10.1152/jappl.1988.65.2.519 Garvican, L. A., Eastwood, A., Martin, D. T., Ross, M. L. R., Gripper, A., & Gore, C. J. (2010). Stability of Hemoglobin Mass During a 6-Day UCI ProTour Cycling Race. Clinical Journal of Sport Medicine, 20(3), 200-204. https://doi.org/10.1097/JSM.0b013e3181ddcd5b Garvican, L., Martin, D., Quod, M., Stephens, B., Sassi, A., & Gore, C. (2012). Time course of the hemoglobin mass response to natural altitude training in elite endurance cyclists: Altitude training and hemoglobin mass. Scandinavian Journal of Medicine & Science in Sports, 22(1), 95-103. https://doi.org/10.1111/j.1600-0838.2010.01145.x Garvican‐Lewis, L. A., Lobigs, L. M., Equey, T., Goebel, C., Agon, V., McCowan, A., Speers, N., & Schumacher, Y. O. (2020). A multi‐parametric approach to remove the influence of plasma volume on the athlete biological passport during a Union Cycliste Internationale cycling stage race. Drug Testing and Analysis, 12(9), 1252-1263. https://doi.org/10.1002/dta.2878 Garvican-Lewis, L. A., Schumacher, Y. O., Clark, S. A., Christian, R., Menaspà, P., Plowman, J., Stephens, B., Qi, J., Fan, R., He, Y., Martin, D. T., Thompson, K. G., Gore, C. J., & Ma, F. (2014). Stage racing at altitude induces hemodilution despite an increase in hemoglobin mass. Journal of Applied Physiology, 117(5), 463-472. https://doi.org/10.1152/japplphysiol.00242.2014 González-Alonso, J., Crandall, C. G., & Johnson, J. M. (2008). The cardiovascular challenge of exercising in the heat: Hyperthermia challenge to cardiovascular regulation and homeostasis. The Journal of Physiology, 586(1), 45-53. https://doi.org/10.1113/jphysiol.2007.142158 Green, H. J., Sutton, J. R., Coates, G., Ali, M., & Jones, S. (1991). Response of red cell and plasma volume to prolonged training in humans. Journal of Applied Physiology, 70(4), 1810-1815. https://doi.org/10.1152/jappl.1991.70.4.1810 Gregersen, M. I., & Rawson, R. A. (1959). Blood volume. Physiological Reviews, 39(2), 307-342. https://doi.org/10.1152/physrev.1959.39.2.307 Hütler, M., Beneke, R., & Böning, D. (2000). Determination of circulating hemoglobin mass and related quantities by using capillary blood. Medicine and Science in Sports and Exercise, 32(5), 1024-1027. https://doi.org/10.1097/00005768-200005000-00022 Kargotich, S., Goodman, C., Keast, D., Fry, R. W., Garcia-Webb, P., Crawford, P. M., & Morton, A. R. (1997). Influence of exercise-induced plasma volume changes on the interpretation of biochemical data following high-intensity exercise. Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine, 7(3), 185-191. https://doi.org/10.1097/00042752-199707000- 00006 Krumm, B., & Faiss, R. (2021). Factors Confounding the Athlete Biological Passport: A Systematic Narrative Review. Sports Medicine - Open, 7(1), 65. https://doi.org/10.1186/s40798-021-00356-0 Lobigs, L. M., Sottas, P.-E., Bourdon, P. C., Nikolovski, Z., El-Gingo, M., Varamenti, E., Peeling, P., Dawson, B., & Schumacher, Y. O. (2018). A step towards removing plasma volume variance from the Athlete’s Biological Passport: The use of biomarkers to describe vascular volumes from a simple blood test. Drug Testing and Analysis, 10(2), 294-300. https://doi.org/10.1002/dta.2219 Mancera-Soto, E. M., Ramos-Caballero, D. M., Rojas J., J. A., Duque, L., Chaves-Gomez, S., Cristancho-Mejía, E., & Schmidt, W. F.-J. (2022). Hemoglobin Mass, Blood Volume and VO2max of Trained and Untrained Children and Adolescents Living at Different Altitudes. Frontiers in Physiology, 13, 892247. https://doi.org/10.3389/fphys.2022.892247 Mier, C. M., Domenick, M. A., Turner, N. S., & Wilmore, J. H. (1996). Changes in stroke volume and maximal aerobic capacity with increased blood volume in men women. Journal of Applied Physiology, 80(4), 1180-1186. https://doi.org/10.1152/jappl.1996.80.4.1180 Montero, D., & Lundby, C. (2018). Regulation of Red Blood Cell Volume with Exercise Training. En R. Terjung (Ed.), Comprehensive Physiology (1.a ed., pp. 149-164). Wiley. https://doi.org/10.1002/cphy.c180004 Olaf Schumacher, Y., & d′Onofrio, G. (2012). Scientific Expertise and the Athlete Biological Passport: 3 Years of Experience. Clinical Chemistry, 58(6), 979-985. https://doi.org/10.1373/clinchem.2012.183061 Oscai, L. B., Williams, B. T., & Hertig, B. A. (1968). Effect of exercise on blood volume. Journal of Applied Physiology, 24(5), 622-624. https://doi.org/10.1152/jappl.1968.24.5.622 Racinais, S., Alonso, J. M., Coutts, A. J., Flouris, A. D., Girard, O., González-Alonso, J., Hausswirth, C., Jay, O., Lee, J. K. W., Mitchell, N., Nassis, G. P., Nybo, L., Pluim, B. M., Roelands, B., Sawka, M. N., Wingo, J., & Périard, J. D. (2015). Consensus recommendations on training and competing in the heat. British Journal of Sports Medicine, 49(18), 1164-1173. https://doi.org/10.1136/bjsports-2015-094915 Robinson, N., Saugy, J., Schütz, F., Faiss, R., Baume, N., Giraud, S., & Saugy, M. (2019). Worldwide distribution of blood values in elite track and field athletes: Biomarkers of altered erythropoiesis. Drug Testing and Analysis, 11(4), 567-577. https://doi.org/10.1002/dta.2526 Saugy, J. J., Schmoutz, T., & Botrè, F. (2022). Altitude and Erythropoietin: Comparative Evaluation of Their Impact on Key Parameters of the Athlete Biological Passport: A Review. Frontiers in Sports and Active Living, 4, 864532. https://doi.org/10.3389/fspor.2022.864532 Sawka, M. N., Convertino, V. A., Eichner, E. R., Schnieder, S. M., & Young, A. J. (2000). Blood volume: Importance and adaptations to exercise training, environmental stresses, and trauma/sickness: Medicine & Science in Sports & Exercise, 32(2), 332. https://doi.org/10.1097/00005768-200002000- 00012 Schmidt, W., Heinicke, K., Rojas, J., Manuel Gomez, J., Serrato, M., Mora, M., Wolfarth, B., Schmid, A., & Keul, J. (2002). Blood volume and hemoglobin mass in endurance athletes from moderate altitude. Medicine and Science in Sports and Exercise, 34(12), 1934-1940. https://doi.org/10.1097/00005768- 200212000-00012 Schmidt, W., & Prommer, N. (2005). The optimised CO-rebreathing method: A new tool to determine total haemoglobin mass routinely. European Journal of Applied Physiology, 95(5-6), 486-495. https://doi.org/10.1007/s00421-005-0050-3 Schumacher, Y. O., Schmid, A., Grathwohl, D., Bültermann, D., & Berg, A. (2002). Hematological indices and iron status in athletes of various sports and performances. Medicine and Science in Sports and Exercise, 34(5), 869-875. https://doi.org/10.1097/00005768-200205000-00022 Schütz, F., & Zollinger, A. (2018). ABPS: An R Package for Calculating the Abnormal Blood Profile Score. Frontiers in Physiology, 9, 1638. https://doi.org/10.3389/fphys.2018.01638 Sedano, Rodrigo, Pupiales, Juan, & Poussery, Lionel (Directores). (2022, octubre 1). El dopaje, un flagelo que empaña el brillo del ciclismo colombiano [Digital]. En El dopaje, un flagelo que empaña el brillo del ciclismo colombiano. France 24. https://www.france24.com/es/programas/reporteros/20221011-el-dopaje-un-flagelo-que- empa%C3%B1a-el-brillo-del-ciclismo-colombiano Siebenmann, C., Robach, P., & Lundby, C. (2017). Regulation of blood volume in lowlanders exposed to high altitude. Journal of Applied Physiology, 123(4), 957-966. https://doi.org/10.1152/japplphysiol.00118.2017 Sottas, P.-E., Robinson, N., Rabin, O., & Saugy, M. (2011). The Athlete Biological Passport. Clinical Chemistry, 57(7), 969-976. https://doi.org/10.1373/clinchem.2011.162271 Stanley, J., Halliday, A., D’Auria, S., Buchheit, M., & Leicht, A. S. (2015). Effect of sauna-based heat acclimation on plasma volume and heart rate variability. European Journal of Applied Physiology, 115(4), 785-794. https://doi.org/10.1007/s00421-014-3060-1 Trompetero González, A. C., , Cristancho Mejía, E., Benavides Pinzón, W. F., Serrato Roa, M., & Landinez Macias, M. P. (2015). Comportamiento de la concentración de hemoglobina, el hematocrito y la saturación de oxígeno en una población universitaria en Colombia a diferentes alturas. [Universidad Nacional de Colombia]. https://doi.org/10.3305/nh.2015.32.5.9711 Tyler, C. J., Reeve, T., Hodges, G. J., & Cheung, S. S. (2016). The Effects of Heat Adaptation on Physiology, Perception and Exercise Performance in the Heat: A Meta-Analysis. Sports Medicine, 46(11), 1699-1724. https://doi.org/10.1007/s40279-016-0538-5 Wachsmuth, N. B., Völzke, C., Prommer, N., Schmidt-Trucksäss, A., Frese, F., Spahl, O., Eastwood, A., Stray-Gundersen, J., & Schmidt, W. (2013). The effects of classic altitude training on hemoglobin mass in swimmers. European Journal of Applied Physiology, 113(5), 1199-1211. https://doi.org/10.1007/s00421-012-2536-0 WADA. (2021). Athlete Biological Passport (ABP) Operating Guidelines. https://www.wada- ama.org/sites/default/files/resources/files/guidelines_abp_en_ 16042019.pdf. Young, A. J., Karl, J. P., Berryman, C. E., Montain, S. J., Beidleman, B. A., & Pasiakos, S. M. (2019). Variability in human plasma volume responses during high‐altitude sojourn. Physiological Reports, 7(6). https://doi.org/10.14814/phy2.14051 Zorzoli, M., & Rossi, F. (2012). Case studies on ESA-doping as revealed by the Biological Passport: Case studies on ESA-doping as revealed by the Biological Passport. Drug Testing and Analysis, 4(11), 854- 858. https://doi.org/10.1002/dta.1340
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dc.format.extent.spa.fl_str_mv	39 páginas
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dc.publisher.spa.fl_str_mv	Universidad Nacional de Colombia
dc.publisher.program.spa.fl_str_mv	Bogotá - Medicina - Maestría en Fisiología
dc.publisher.faculty.spa.fl_str_mv	Facultad de Medicina
dc.publisher.place.spa.fl_str_mv	Bogotá, Colombia
dc.publisher.branch.spa.fl_str_mv	Universidad Nacional de Colombia - Sede Bogotá
institution	Universidad Nacional de Colombia
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spelling	Atribución-CompartirIgual 4.0 Internacionalhttp://creativecommons.org/licenses/by-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Cristancho Mejía, Edgar0eca152d0442cc5ef1aaf16a6ba92862Mancera Soto, Erica8de5f334ac07d11caf9a6d4fda1440d3Espitia Porras, Laura Fernandafdf35bd42775a55c64d9b55b5abc1662Grupo de Investigacion en Adaptaciones Al Ejercicio y A la Hipoxia2023-08-28T14:53:09Z2023-08-28T14:53:09Z2023https://repositorio.unal.edu.co/handle/unal/84603Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramasLa exposición aguda de ciclistas residentes y entrenados en altitud a mayor temperatura y presión barométrica disminuye marcadores sanguíneos debido a la expansión del volumen plasmático (VP). Se hizo seguimiento de la respuesta de marcadores sanguíneos como concentración de hemoglobina, hematocrito, volumen plasmático e índice de estimulación (Off-score) a diez hombres ciclistas de ruta que residen y entrenan en altitud moderada (2500 m, 456 mmHg, 22°C) durante un campamento de entrenamiento de siete días a menor altitud (456 m, 566 mmHg, 26°C). La concentración de hemoglobina disminuyó hasta 1.4 g/dl ,el hematocrito hasta 3.3%, el volumen plasmático aumentó hasta 644 ml y el marcador Off-score varió hasta 17.1 puntos. El seguimiento de la variación de dichos marcadores sanguíneos medidos en el pasaporte biológico del atleta (PBA) frente a variaciones de las condiciones ambientales, estableció rangos de variación del Off-Score, lo que permite mejorar el control de sustancias prohibidas en el deporte. (Texto tomado de la fuente)Acute exposure of resident and altitude-trained cyclists to higher temperature and barometric pressure decreases blood markers due to expansion of plasma volume (PV). The response of blood markers such as haemoglobin concentration, hematocrit, plasma volume and stimulation index (Off-score) was monitored in 10 male road cyclists residing and training at moderate altitude (2500 m, 456 mmHg, 22°C) during a 7-day training camp at lower altitude (456 m, 566 mmHg, 26°C). Hemoglobin concentration decreased to 1. 4 g/dl, hematocrit to 3. 3%, plasma volume increased to 644 ml and the Off-score marker varied to 17. 1 points. The monitoring of the variation of these blood markers measured in the athlete's biological passport (PBA) against variations in environmental conditions, established ranges of variation of the Off-Score, which allows to improve the control of prohibited substances in sport.MaestríaMagister en FisiologíaFisiología del ejercicio39 páginasapplication/pdfUniversidad Nacional de ColombiaBogotá - Medicina - Maestría en FisiologíaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y salud::612 - Fisiología humana790 - Deportes, juegos y entretenimiento::796 - Deportes y juegos al aire libre y deportivosAtletasAthletesCiclistasDeportistasCyclistsAthletesVolumen plasmáticoEjercicioPasaporte Biológico del AtletaPBAOff-ScorePlasma volumeExerciseBiological Passport of AthleteBPAOff-ScoreVariación del volumen plasmático como factor de confusión en el pasaporte biológico hematológicoVariation in plasma volumene as a confounding factor in the haematological biological passportTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMAshenden, M., Gough, C. E., Garnham, A., Gore, C. J., & Sharpe, K. (2011). Current markers of the Athlete Blood Passport do not flag microdose EPO doping. European Journal of Applied Physiology, 111(9), 2307-2314. https://doi.org/10.1007/s00421-011-1867-6Astolfi, T., Crettaz von Roten, F., Kayser, B., Saugy, M., & Faiss, R. (2021). The Influence of Training Load on Hematological Athlete Biological Passport Variables in Elite Cyclists. Frontiers in Sports and Active Living, 3, 618285. https://doi.org/10.3389/fspor.2021.618285Beidleman, B. A., Staab, J. E., Muza, S. R., & Sawka, M. N. (2017). Quantitative model of hematologic and plasma volume responses after ascent and acclimation to moderate to high altitudes. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 312(2), R265-R272. https://doi.org/10.1152/ajpregu.00225.2016Bejder, J., Hoffmann, M. F., Ashenden, M., Nordsborg, N. B., Karstoft, K., & Mørkeberg, J. (2016). Acute hyperhydration reduces athlete biological passport OFF-hr score: Hyperhydration and athlete biological passport. Scandinavian Journal of Medicine & Science in Sports, 26(3), 338-347. https://doi.org/10.1111/sms.12438Böning, D. (2019). Der kolumbianische Tour de France-Sieger Egan Bernal: Sportphysiologische Hintergründe. Deutsche Zeitschrift für Sportmedizin, 70(9), 195-196. https://doi.org/10.5960/dzsm.2019.397Böning, D., Rojas, J., Serrato, M., Ulloa, C., Coy, L., Mora, M., Gomez, J., & Hütler, M. (2001). Hemoglobin mass and peak oxygen uptake in untrained and trained residents of moderate altitude. International Journal of Sports Medicine, 22(8), 572-578. https://doi.org/10.1055/s-2001-18530Buchheit, M., Laursen, P. B., Al Haddad, H., & Ahmaidi, S. (2009). Exercise-induced plasma volume expansion and post-exercise parasympathetic reactivation. European Journal of Applied Physiology, 105(3), 471-481. https://doi.org/10.1007/s00421-008-0925-1Burge, C. M., & Skinner, S. L. 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Drug Testing and Analysis, 4(11), 854- 858. https://doi.org/10.1002/dta.1340VARIACIÓN DEL VOLUMEN PLASMÁTICO COMO FACTOR DE CONFUSIÓN EN EL PASAPORTE BIOLÓGICO HEMATOLÓGICOUNIVERSIDAD NACIONAL DE COLOMBIAMINISTERIO DEL DEPORTEEstudiantesInvestigadoresMaestrosPadres y familiasPúblico generalLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/84603/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINAL1019124522.2023.pdf1019124522.2023.pdfTesis de Maestría en Fisiologíaapplication/pdf1092440https://repositorio.unal.edu.co/bitstream/unal/84603/3/1019124522.2023.pdffc93f48877a8504a4cb4796e4f94d25aMD53THUMBNAIL1019124522.2023.pdf.jpg1019124522.2023.pdf.jpgGenerated Thumbnailimage/jpeg5316https://repositorio.unal.edu.co/bitstream/unal/84603/4/1019124522.2023.pdf.jpg73307ec11a9503dddcbff39067e7383dMD54unal/84603oai:repositorio.unal.edu.co:unal/846032024-08-07 23:10:43.179Repositorio Institucional Universidad Nacional de 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Variación del volumen plasmático como factor de confusión en el pasaporte biológico hematológico

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