Estudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021
ilustraciones, gráficas, tablas
- Autores:
-
Rojas Perdomo, Juan David
- Tipo de recurso:
- Fecha de publicación:
- 2021
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/80931
- Palabra clave:
- 610 - Medicina y salud
Health Services Research
Neoplasms
Respiratory Tract Diseases
Investigación sobre Servicios de Salud
Neoplasias
Enfermedades Respiratorias
COVID-19
Infección respiratoria aguda
Síndrome de distrés respiratorio
Neumonía
Choque séptico
Neoplasias malignas
Estudio cohorte
COVID-19
Malignant Neoplasms
Cohort studies
Pneumonia
Acute respiratory infection
Respiratory distress syndrome
Septic shock
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional
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| dc.title.spa.fl_str_mv |
Estudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021 |
| dc.title.translated.eng.fl_str_mv |
Study cohort of patients with malignant neoplasms treated for Acute Respiratory Infection in the Instituto Nacional de Cancerologia (INC) during the COVID-19 pandemic from May 2020 to August 2021 |
| title |
Estudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021 |
| spellingShingle |
Estudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021 610 - Medicina y salud Health Services Research Neoplasms Respiratory Tract Diseases Investigación sobre Servicios de Salud Neoplasias Enfermedades Respiratorias COVID-19 Infección respiratoria aguda Síndrome de distrés respiratorio Neumonía Choque séptico Neoplasias malignas Estudio cohorte COVID-19 Malignant Neoplasms Cohort studies Pneumonia Acute respiratory infection Respiratory distress syndrome Septic shock |
| title_short |
Estudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021 |
| title_full |
Estudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021 |
| title_fullStr |
Estudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021 |
| title_full_unstemmed |
Estudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021 |
| title_sort |
Estudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021 |
| dc.creator.fl_str_mv |
Rojas Perdomo, Juan David |
| dc.contributor.advisor.spa.fl_str_mv |
Cuervo Maldonado, Sonia Isabel Carolina, Wiesner Ceballos Gómez Rincón, Julio César Sánchez, Ricardo Montañez Ayala, Anita María García Guzmán, Katherine |
| dc.contributor.author.spa.fl_str_mv |
Rojas Perdomo, Juan David |
| dc.contributor.researchgroup.spa.fl_str_mv |
Greicah Grupo en Enfermedades Infecciosas en Cáncer y Alteraciones Hematológicas |
| dc.subject.ddc.spa.fl_str_mv |
610 - Medicina y salud |
| topic |
610 - Medicina y salud Health Services Research Neoplasms Respiratory Tract Diseases Investigación sobre Servicios de Salud Neoplasias Enfermedades Respiratorias COVID-19 Infección respiratoria aguda Síndrome de distrés respiratorio Neumonía Choque séptico Neoplasias malignas Estudio cohorte COVID-19 Malignant Neoplasms Cohort studies Pneumonia Acute respiratory infection Respiratory distress syndrome Septic shock |
| dc.subject.decs.eng.fl_str_mv |
Health Services Research Neoplasms Respiratory Tract Diseases |
| dc.subject.decs.spa.fl_str_mv |
Investigación sobre Servicios de Salud Neoplasias Enfermedades Respiratorias |
| dc.subject.proposal.spa.fl_str_mv |
COVID-19 Infección respiratoria aguda Síndrome de distrés respiratorio Neumonía Choque séptico Neoplasias malignas Estudio cohorte |
| dc.subject.proposal.eng.fl_str_mv |
COVID-19 Malignant Neoplasms Cohort studies Pneumonia Acute respiratory infection Respiratory distress syndrome Septic shock |
| description |
ilustraciones, gráficas, tablas |
| publishDate |
2021 |
| dc.date.issued.none.fl_str_mv |
2021-12-24 |
| dc.date.accessioned.none.fl_str_mv |
2022-02-10T15:24:48Z |
| dc.date.available.none.fl_str_mv |
2022-02-10T15:24:48Z |
| dc.type.spa.fl_str_mv |
Trabajo de grado - Especialidad Médica |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/masterThesis |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
| dc.type.content.spa.fl_str_mv |
Text |
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http://purl.org/redcol/resource_type/TM |
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acceptedVersion |
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https://repositorio.unal.edu.co/handle/unal/80931 |
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Universidad Nacional de Colombia |
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Repositorio Institucional Universidad Nacional de Colombia |
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https://repositorio.unal.edu.co/ |
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https://repositorio.unal.edu.co/handle/unal/80931 https://repositorio.unal.edu.co/ |
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Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
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spa |
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Bireme |
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Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China. JAMA 2020;323:1061–9. Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020;395:507–13. Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez-Ocampo E, Villamizar-Peña R, Holguin-Rivera Y, Escalera-Antezana JP, et al. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Med Infect Dis 2020:101623. Saavedra Trujillo CH. Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-COV-2/COVID 19 en establecimientos de atención de la salud. Recomendaciones basadas en consenso de expertos e informadas en la evidencia. Infectio 2020;24:1. Yu J, Ouyang W, Chua MLK, Xie C. SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China. JAMA Oncol 2020. Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020:NEJMoa2002032. MacIntyre CR, Chughtai AA, Barnes M, Ridda I, Seale H, Toms R, et al. The role of pneumonia and secondary bacterial infection in fatal and serious outcomes of pandemic influenza a(H1N1)pdm09 11 Medical and Health Sciences 1103 Clinical Sciences 11 Medical and Health Sciences 1117 Public Health and Health Services. BMC Infect Dis 2018;18:637. Klein EY, Monteforte B, Gupta A, Jiang W, May L, Hsieh YH, et al. The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis. Influenza Other Respi Viruses 2016;10:394–403. Anexo versión 9. Instituto Nacional de Salud. Instructivo para la vigilancia en salud pública intensificada de infección respiratoria aguda asociada al nuevo coronavirus 2019 (COVID-19) 2020;Versión 9. Kamboj M, Sepkowitz KA. Nosocomial infections in patients with cancer. Lancet Oncol 2009;10:589–97. Liang W, Guan W, Chen R, Wang W, Li J, Xu K, et al. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. Lancet Oncol 2020;21:335–7. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020;395:1054–62. Ministerio de Salud y protección social C, Instituto Nacional de Cancerología C. Plan Decenal para el Control del Cáncer en Colombia, 2012 – 2021 2012. Morens DM, Fauci AS. The 1918 Influenza Pandemic: Insights for the 21st Century. J Infect Dis 2007;195:1018–28. Dauer CC, Serfling RE. Mortality from Influenza. Am Rev Respir Dis 1961;83:15–28. Alling DW, Blackwelder WC, Stuart-Harris CH. A study of excess mortality during influenza epidemics in the United States, 1968-1976. Am J Epidemiol 1981;113:30–43. Morens DM, Taubenberger JK, Fauci AS. Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness. J Infect Dis 2008;198:962–70. Booth CM. Clinical Features and Short-term Outcomes of 144 Patients With SARS in the Greater Toronto Area. JAMA 2003;289:2801. Martín-Loeches I, Sanchez-Corral A, Diaz E, Granada RM, Zaragoza R, Villavicencio C, et al. Community-acquired respiratory coinfection in critically III patients with pandemic 2009 influenza A(H1N1) virus. Chest 2011;139:555–62. Lee EH, Wu C, Lee EU, Stoute A, Hanson H, Cook HA, et al. Fatalities Associated with the 2009 H1N1 Influenza A Virus in New York City. Clin Infect Dis 2010;50:1498–504. Wu X, Cai Y, Huang X, Yu X, Zhao L, Wang F, et al. Co-infection with SARS-CoV-2 and Influenza A Virus in Patient with Pneumonia, China. Emerg Infect Dis 2020;26. Touzard-Romo F, Tapé C, Lonks JR. Co-infection with SARS-CoV-2 and Human Metapneumovirus. R I Med J (2013) 2020;103:75–6. Vilar-Compte D, Shah DP, Vanichanan J, Cornejo-Juarez P, Garcia-Horton A, Volkow P, et al. Influenza in patients with hematological malignancies: Experience at two comprehensive cancer centers. J Med Virol 2018;90:50–60. Choi SM, Boudreault AA, Xie H, Englund JA, Corey L, Boeckh M. Differences in clinical outcomes after 2009 influenza A/H1N1 and seasonal influenza among hematopoietic cell transplant recipients. Blood 2011;117:5050–6. Tai Y, Lee TC, Chang HL, Chen KT. Epidemiology and outcomes of hospitalization of influenza in the cancer population in Taiwan. J Cancer Res Clin Oncol 2009;135:1061–6. Mikulska M, Del Bono V, Gandolfo N, Dini S, Dominietto A, Di Grazia C, et al. Epidemiology of viral respiratory tract infections in an outpatient haematology facility. Ann Hematol 2014;93:669–76. Redelman-Sidi G, Sepkowitz KA, Huang CK, Park S, Stiles J, Eagan J, et al. 2009 H1N1 influenza infection in cancer patients and hematopoietic stem cell transplant recipients. J Infect 2010;60:257–63. Saad M, Hayajneh W, Mubarak S, Yousef I, Awad H, Elbjeirami W, et al. Clinical presentations and outcomes of influenza infection among hematology/oncology patients from a single cancer center: Pandemic and post-pandemic seasons. Scand J Infect Dis 2014;46:770–8. Falsey AR, McElhaney JE, Beran J, van Essen GA, Duval X, Esen M, et al. Respiratory syncytial virus and other respiratory viral infections in older adults with moderate to severe influenza-like illness. J Infect Dis 2014;209:1873–81. Livingston E, Bucher K, Rekito A. Coronavirus Disease 2019 and Influenza 2019-2020. JAMA 2020;323:1122. Weng TC, Chiu HYR, Chen SY, Shih FY, King CC, Fang CC. National retrospective cohort study to identify age-specific fatality risks of comorbidities 012019;9:e025276. Dhanoa A, Fang NC, Hassan SS, Kaniappan P, Rajasekaram G. Epidemiology and clinical characteristics of hospitalized patients with pandemic influenza A (H1N1) 2009 infections: The effects of bacterial coinfection. Virol J 2011;8:501. NM K, TK C, DP S, Y S, SM R, DR R, et al. Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study. Lancet (London, England) 2020;395:1907–18. Group TRC. Dexamethasone in Hospitalized Patients with Covid-19. Https://DoiOrg/101056/NEJMoa2021436 2020;384:693–704. Desai A, Gupta R, Advani S, Ouellette L, Kuderer NM, Lyman GH, et al. Mortality in hospitalized patients with cancer and coronavirus disease 2019: A systematic review and meta-analysis of cohort studies. Cancer 2021;127:1459–68. Yang K, Sheng Y, Huang C, Jin Y, Xiong N, Jiang K, et al. Clinical characteristics, outcomes, and risk factors for mortality in patients with cancer and COVID-19 in Hubei, China: a multicentre, retrospective, cohort study. Lancet Oncol 2020;21:904–13. Pinato DJ, Lee AJX, Biello F, Seguí E, Aguilar-Company J, Carbó A, et al. Presenting Features and Early Mortality from SARS-CoV-2 Infection in Cancer Patients during the Initial Stage of the COVID-19 Pandemic in Europe. Cancers 2020, Vol 12, Page 1841 2020;12:1841. J J, MB F, M L, AJ S, B W, V N, et al. Chemotherapy and COVID-19 Outcomes in Patients With Cancer. J Clin Oncol 2020;38:3538–46. Pinato DJ, Zambelli A, Aguilar-Company J, Bower M, Sng CCT, Salazar R, et al. Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer. Cancer Discov 2020;10:1465–74. National Institute for Health and Care Excellence (NICE). COVID-19 Rapid Guideline: Delivery of SystemicAnticancer Treatments NICE Guideline Rivera DR, Peters S, Panagiotou OA, Shah DP, Kuderer NM, Hsu CY, et al. Utilization of COVID-19 Treatments and Clinical Outcomes among Patients with Cancer: A COVID-19 and Cancer Consortium (CCC19) Cohort Study. Cancer Discov 2020;10:1514–27. Dettorre GM, Dolly S, Loizidou A, Chester J, Jackson A, Mukherjee U, et al. Systemic pro-inflammatory response identifies patients with cancer with adverse outcomes from SARS-CoV-2 infection: the OnCovid Inflammatory Score. J Immunother Cancer 2021;9:2277. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA 2020;323:1239–42. Palmieri C, Turtle L, Docherty A, Harrison E, Drake T, Greenhalf B, et al. 1670O Prospective data of first 1,797 hospitalised patients with cancer and COVID-19 derived from the COVID-19 Clinical Information Network and international Severe Acute Respiratory and emerging Infections Consortium, WHO Coronavirus Clinical Characterisation Consortium. Ann Oncol 2020;31:S992. Li A, Kuderer NM, Hsu CY, Shyr Y, Warner JL, Shah DP, et al. The CoVID-TE risk assessment model for venous thromboembolism in hospitalized patients with cancer and COVID-19. J Thromb Haemost 2021;19:2522–32. S R, JS H, M N, JM C, T M, KW D, et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA 2020;323:2052–9. Petrilli CM, Jones SA, Yang J, Rajagopalan H, O’Donnell L, Chernyak Y, et al. Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study. BMJ 2020;369. AV O, R B, W M, I T, P R, S A, et al. Impact of COVID-19 Infection on Patients with Cancer: Experience in a Latin American Country: The ACHOCC-19 Study. Oncologist 2021;26:e1761–73. Kuderer NM, Wulff-Burchfield E, Rubinstein SM, Grivas P, Warner JL. Cancer and COVID-19 – Authors’ reply. Lancet 2020;396:1067–8. Marron JM, Joffe S, Jagsi R, Spence RA, Hlubocky FJ. Ethics and Resource Scarcity: ASCO Recommendations for the Oncology Community During the COVID-19 Pandemic. J Clin Oncol 2020;38:2201–5 |
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xvii, 59 páginas |
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2020-2021 |
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Universidad Nacional de Colombia |
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Bogotá - Medicina - Especialidad en Medicina Interna |
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Departamento de Medicina Interna |
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Facultad de Medicina |
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Bogotá, Colombia |
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Universidad Nacional de Colombia - Sede Bogotá |
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Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Cuervo Maldonado, Sonia Isabel8b45c15b8c35afce253a5861965c00f8600Carolina, Wiesner Ceballosb47d979090a526467306cedf18cc5e4d600Gómez Rincón, Julio César23ebca40d4dfed9e79b059621839f097600Sánchez, Ricardodb503ef6bc4fc2626727a8658bb76600600Montañez Ayala, Anita Maríaa818bff6dfb02253e85dfa501b53af59600García Guzmán, Katherine89b67e3be720ffb83e95832e089aeb55600Rojas Perdomo, Juan David428fd610559588016ff411a73fca4685600Greicah Grupo en Enfermedades Infecciosas en Cáncer y Alteraciones Hematológicas2020-20212022-02-10T15:24:48Z2022-02-10T15:24:48Z2021-12-24https://repositorio.unal.edu.co/handle/unal/80931Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, gráficas, tablasEstudio de Cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021 Introducción: Los pacientes con neoplasias malignas son una población de alto riesgo. Se describe una caracterización exhaustiva de pacientes con cáncer e infección respiratoria aguda (IRA) durante la pandemia por COVID-19 y se analizan factores de riesgo para ventilación mecánica invasiva y muerte en esta población. Métodos: Estudio de cohorte ambispectivo, de 644 pacientes con IRA y cáncer desde Mayo de 2020 a Agosto de 2021. Se realizó seguimiento a 30 días del egreso hospitalario. Características clínicas, paraclínicas, imagenológicas e historia de cáncer fueron comparados entre sobrevivientes y no sobrevivientes, y entre positivos y negativos para COVID-19. Factores de riesgo para ventilación mecánica invasiva y muerte fueron identificados usando modelos de regresión logística univariable y multivariables. Resultados: 644 pacientes con IRA y neoplasias malignas fueron abarcados (mediana edad 60 años (IQR 23);48.5% mujeres). 421 (65.3%) tenían tumores sólidos y 219 (34%) hematológicos. El más frecuente fue el cáncer de mama (67/421) seguido por colorrectal (46/421) y próstata (42/421) (15%, 10% y 9% respectivamente). 161 (25%) recibieron quimioterapia en los 30 días previos al diagnóstico de IRA. 30.4% de los pacientes ingresó a UCI y 93.8% requirió ventilación mecánica invasiva. La mortalidad global a 30 días fue del 50.4%, 53.7% en el grupo de infección por COVID 19. 60.17% directamente relacionado a IRA y 31.23% asociado a neoplasia maligna de base. Conclusiones: Los pacientes con neoplasias malignas e IRA quienes fueron admitidos al hospital tiene una alta tasa de mortalidad no relacionado a la identificación de SARS-CoV2 como agente causal. (Texto tomado de la fuente).Study cohort of patients with malignant neoplasms treated for Acute Respiratory Infection in the Instituto Nacional de Cancerologia (INC) during the COVID-19 pandemic from May 2020 to August 2021 Introduction: Patients with malignant neoplasms are a high-risk population. A comprehensive characterization of cancer patients with acute respiratory infection (ARI) during the COVID-19 pandemic is described and risk factors for invasive mechanical ventilation and death in this population are analyzed. Methods: Ambispective cohort study of 644 patients with ARI and cancer, from May 2020 to August 2021. Follow-up was carried out 30 days after hospital discharge. Clinical, paraclinical, imaging characteristics and history of cancer were compared between survivors and non-survivors, and between positive and negative COVID-19 cases. Risk factors for invasive mechanical ventilation and death were identified using univariate and multivariate logistic regression models. Results: 644 patients with ARI and malignant neoplasms were included (median age: 60 years (IQR 23); 48.5% women). 421 (65.3%) had solid tumors and 219 (34%) hematological ones. The most frequent was breast cancer (67/421) followed by colorectal (46/421) and prostate (42/421) (15%, 10% and 9% respectively). 161 (25%) received chemotherapy in the 30 days prior to ARI diagnosis. 30.4% of the patients were admitted to the ICU and 93.8% required invasive mechanical ventilation. Overall 30-day mortality was 50.4%, 53.7% in the COVID-19 infection group. 60.17% directly related to ARI and 31.23% associated with the underlying malignancy. Conclusions: Patients with malignant neoplasms and ARI admitted to the hospital had a high mortality rate not related to the identification of SARS-CoV2 as a causal agent.Incluye anexosEspecialidades MédicasEspecialista en Medicina InternaEstudio observacional, analítico, de cohorte ambispectivo.Epidemiología descriptiva y sistemas de vigilancia del cáncerxvii, 59 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Especialidad en Medicina InternaDepartamento de Medicina InternaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y saludHealth Services ResearchNeoplasmsRespiratory Tract DiseasesInvestigación sobre Servicios de SaludNeoplasiasEnfermedades RespiratoriasCOVID-19Infección respiratoria agudaSíndrome de distrés respiratorioNeumoníaChoque sépticoNeoplasias malignasEstudio cohorteCOVID-19Malignant NeoplasmsCohort studiesPneumoniaAcute respiratory infectionRespiratory distress syndromeSeptic shockEstudio de cohorte de pacientes con neoplasias malignas atendidos por infección respiratoria aguda (IRA) en el Instituto Nacional de Cancerología (INC) durante la pandemia por COVID-19 mayo 2020- agosto 2021Study cohort of patients with malignant neoplasms treated for Acute Respiratory Infection in the Instituto Nacional de Cancerologia (INC) during the COVID-19 pandemic from May 2020 to August 2021Trabajo de grado - Especialidad Médicainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMBiremeWang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China. JAMA 2020;323:1061–9.Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020;395:507–13.Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez-Ocampo E, Villamizar-Peña R, Holguin-Rivera Y, Escalera-Antezana JP, et al. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Med Infect Dis 2020:101623.Saavedra Trujillo CH. Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-COV-2/COVID 19 en establecimientos de atención de la salud. Recomendaciones basadas en consenso de expertos e informadas en la evidencia. Infectio 2020;24:1.Yu J, Ouyang W, Chua MLK, Xie C. SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China. 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