Malignant bone tumors in Pediatrics. Five year experience in a pediatric referral center

Background: Osteosarcoma (OS) and Ewing’s Sarcoma (ES) are the two most common malignant bone tumors in children. A retrospective review of the records of children diagnosed in a pediatric hospital over a five year period (2008-2013) was performed.Objective: To present the experiences acquired during the treatment of these types of tumors and to compare the results obtained with those reported in the literature.Methodology: The database of the Oncology and Pathology Service of Fundación Hospital de la Misericordia (HOMI) was reviewed to identify patients with primary bone tumors referred for histopathology analysis.Results: 22 patients were diagnosed with OS, with a mean age of 11.9 years. 96% of cases were located in the lower extremities. All patients received neoadjuvant chemotherapy and 86% underwent surgical treatment; 13% survived. 15 patients were diagnosed with ES, with a mean age of 12.4 years. 67% of cases were located in flat bones, 53% of patients had metastasis when diagnosed, and all received neoadjuvant chemotherapy. 40% of patients received surgical intervention and 20% received radiotherapy. Survival at the completion of the reseearch was 33%.Conclusions: Cure and survival rates are lower than those reported in the literature despite efforts to improve treatments.

• Autores: Barros, Gisela; Trujillo, Angela María; Jaramillo, Lina; Ortiz, Francy Helena; Contreras, Agustin Dario
• Tipo de recurso: Article of journal
• Fecha de publicación: 2016
• Institución: Universidad Nacional de Colombia
• Repositorio: Universidad Nacional de Colombia
• Idioma: spa
• OAI Identifier: oai:repositorio.unal.edu.co:unal/65187
• Acceso en línea: https://repositorio.unal.edu.co/handle/unal/65187; http://bdigital.unal.edu.co/66210/
• Palabra clave: 61 Ciencias médicas; Medicina / Medicine and health; Osteosarcoma; Ewing’s Sarcoma; Disease Progression; Recurrence; Neoplasm Metastasis; Osteosarcoma; Sarcoma de Ewing; Progresión de la enfermedad; Recurrencia; Metástasis de la neoplasia
• Rights: openAccess
• License: Atribución-NoComercial 4.0 Internacional