Complex relationships between structural changes using brain Magnetic Resonance imaging in early diagnosis of Alzheimer's Disease

Neurodegenerative disease is the term used for a sort of incurable pathologies present in the brain. It results in progressive degeneration of nerve cells, leading to movement ata- xias, or mental dementias. Dementias are responsible for greatest burden of disease with Alzheimer's representing...

Full description

Autores:
Pulido Chadid, Andrea Marcella
Tipo de recurso:
Fecha de publicación:
2014
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/52248
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/52248
http://bdigital.unal.edu.co/46567/
Palabra clave:
57 Ciencias de la vida; Biología / Life sciences; biology
61 Ciencias médicas; Medicina / Medicine and health
62 Ingeniería y operaciones afines / Engineering
Magnetic Resonance Imaging
Visual Attention Models
Probabilistic Latent Semantic Analysis
Alzheimer's disease
Neurodegenerative diseases
Imágenes de Resonancia Magnética
Modelos de Atención Visual
Análisis Probabilístico de semántica latente
Enfermedad de Alzheimer
Enfermedades Neurodegenerativas
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
Description
Summary:Neurodegenerative disease is the term used for a sort of incurable pathologies present in the brain. It results in progressive degeneration of nerve cells, leading to movement ata- xias, or mental dementias. Dementias are responsible for greatest burden of disease with Alzheimer's representing approximately 60-70% of cases. The main goal of this thesis is to highlight subtle anatomical differences that constitute abnormal structural patterns that may indicate the presence or absence of the pathology in regions with similar visual features by using Brain Magnetic Resonance Imaging.