Fisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatal
ilustraciones, diagramas, fotografías, tablas
- Autores:
-
Lamprea Rodríguez, Sandra Milena
- Tipo de recurso:
- Fecha de publicación:
- 2024
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/87066
- Palabra clave:
- 610 - Medicina y salud::612 - Fisiología humana
610 - Medicina y salud::618 - Ginecología, obstetricia, pediatría, geriatría
Recien Nacido Prematuro
Unidades de Cuidado Intensivo Neonatal
Trastornos del Neurodesarrollo
Conducta en la Lactancia
Deglución
Infant, Premature
Intensive Care, Neonatal
Neurodevelopmental Disorders
Sucking Behavior
Deglutition
Neonato pretérmino
Voz materna
Patrón de succión
Saturación de oxígeno
Neurodesarrollo
Neurodevelopment
Preterm newborn
Maternal voice
Sucking pattern
Oxygen saturation
- Rights
- openAccess
- License
- Atribución-SinDerivadas 4.0 Internacional
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dc.title.spa.fl_str_mv |
Fisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatal |
dc.title.translated.eng.fl_str_mv |
Physiology of the sucking:swallowing:breathing process during exposure to maternal voice in preterm neonates in the neonatal intensive care unit |
title |
Fisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatal |
spellingShingle |
Fisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatal 610 - Medicina y salud::612 - Fisiología humana 610 - Medicina y salud::618 - Ginecología, obstetricia, pediatría, geriatría Recien Nacido Prematuro Unidades de Cuidado Intensivo Neonatal Trastornos del Neurodesarrollo Conducta en la Lactancia Deglución Infant, Premature Intensive Care, Neonatal Neurodevelopmental Disorders Sucking Behavior Deglutition Neonato pretérmino Voz materna Patrón de succión Saturación de oxígeno Neurodesarrollo Neurodevelopment Preterm newborn Maternal voice Sucking pattern Oxygen saturation |
title_short |
Fisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatal |
title_full |
Fisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatal |
title_fullStr |
Fisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatal |
title_full_unstemmed |
Fisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatal |
title_sort |
Fisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatal |
dc.creator.fl_str_mv |
Lamprea Rodríguez, Sandra Milena |
dc.contributor.advisor.spa.fl_str_mv |
Sampallo Pedroza, Rosa Mercedes Zuluaga, Jairo Alberto |
dc.contributor.author.spa.fl_str_mv |
Lamprea Rodríguez, Sandra Milena |
dc.contributor.researchgroup.spa.fl_str_mv |
Voz, Habla y Deglución |
dc.contributor.orcid.spa.fl_str_mv |
Lamprea Rodríguez, Sandra Milena [0000000248845761] |
dc.subject.ddc.spa.fl_str_mv |
610 - Medicina y salud::612 - Fisiología humana 610 - Medicina y salud::618 - Ginecología, obstetricia, pediatría, geriatría |
topic |
610 - Medicina y salud::612 - Fisiología humana 610 - Medicina y salud::618 - Ginecología, obstetricia, pediatría, geriatría Recien Nacido Prematuro Unidades de Cuidado Intensivo Neonatal Trastornos del Neurodesarrollo Conducta en la Lactancia Deglución Infant, Premature Intensive Care, Neonatal Neurodevelopmental Disorders Sucking Behavior Deglutition Neonato pretérmino Voz materna Patrón de succión Saturación de oxígeno Neurodesarrollo Neurodevelopment Preterm newborn Maternal voice Sucking pattern Oxygen saturation |
dc.subject.decs.spa.fl_str_mv |
Recien Nacido Prematuro Unidades de Cuidado Intensivo Neonatal Trastornos del Neurodesarrollo Conducta en la Lactancia Deglución |
dc.subject.decs.eng.fl_str_mv |
Infant, Premature Intensive Care, Neonatal Neurodevelopmental Disorders Sucking Behavior Deglutition |
dc.subject.proposal.spa.fl_str_mv |
Neonato pretérmino Voz materna Patrón de succión Saturación de oxígeno Neurodesarrollo Neurodevelopment |
dc.subject.proposal.eng.fl_str_mv |
Preterm newborn Maternal voice Sucking pattern Oxygen saturation |
description |
ilustraciones, diagramas, fotografías, tablas |
publishDate |
2024 |
dc.date.accessioned.none.fl_str_mv |
2024-10-25T17:19:29Z |
dc.date.available.none.fl_str_mv |
2024-10-25T17:19:29Z |
dc.date.issued.none.fl_str_mv |
2024 |
dc.type.spa.fl_str_mv |
Trabajo de grado - Maestría |
dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/masterThesis |
dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/acceptedVersion |
dc.type.content.spa.fl_str_mv |
Text |
dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/TM |
status_str |
acceptedVersion |
dc.identifier.uri.none.fl_str_mv |
https://repositorio.unal.edu.co/handle/unal/87066 |
dc.identifier.instname.spa.fl_str_mv |
Universidad Nacional de Colombia |
dc.identifier.reponame.spa.fl_str_mv |
Repositorio Institucional Universidad Nacional de Colombia |
dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.unal.edu.co/ |
url |
https://repositorio.unal.edu.co/handle/unal/87066 https://repositorio.unal.edu.co/ |
identifier_str_mv |
Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
dc.language.iso.spa.fl_str_mv |
spa |
language |
spa |
dc.relation.references.spa.fl_str_mv |
1. World Health Organization. Born Too Soon: The global action report on preterm birth. 2012. 2. McCormick MC, Litt JS, Smith VC, Zupancic JAF. Prematurity: An overview and public health implications. Annu Rev Public Health. 2011;32:367–79. 3. Lubbe W, van der Walt C, Klopper H. NICU environment - What should it be like? J Neonatal Nurs. 2012;18(3):90–3. 4. Bremmer P, Byers JF, Kiehl E. Noise and the premature infant: physiological effects and practice implications. J Obstet Gynecol Neonatal Nurs. 2003;32(4):447–54. 5. Acevedo DH, Becerra JIR, Martínez ÁL. The philosophy of the developmental centred care of the premature infant (NIDCAP): A literature review. Enferm Glob. 2017;16(4):577–602. 6. Maltese A, Gallai B, Marotta R, Lavano F, Lavano S, Tripi G, et al. The synactive theory of development: The keyword for neurodevelopmental disorders. Acta Medica Mediterr [Internet]. 2017;33(June):393–8. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26350424 7. Mooney-Leber SM, Brummelte S. Neonatal pain and reduced maternal care: Early-life stressors interacting to impact brain and behavioral development. Neuroscience [Internet]. 2017;342:21–36. Available from: http://www.sciencedirect.com/science/article/pii/S0306452216301403 8. Bucsea O, Pillai Riddell R. Non-pharmacological pain management in the neonatal intensive care unit: Managing neonatal pain without drugs. Semin Fetal Neonatal Med [Internet]. 2019;24(4):101017. Available from: https://doi.org/10.1016/j.siny.2019.05.009 9. Basch K. Beiträge zur Kenntniss des menschlichen Milchapparats. Arch Gynakol [Internet]. 1893;44(1):15–54. Available from: https://doi.org/10.1007/BF01981179 10. Tamilia E, Taffoni F, Formica D, Ricci L, Schena E, Keller F, et al. Technological solutions and main indices for the assessment of newborns’ Nutritive Sucking: A review. Sensors (Switzerland). 2014;14(1):634–58. 11. Tamilia E, Formica D, Scaini A, Taffoni F. An Automated System for the Analysis of Newborns’ Oral-Motor Behavior. IEEE Trans Neural Syst Rehabil Eng. 2016;24(12):1294–303. 12. Rand K, Lahav A. Maternal sounds elicit lower heart rate in preterm newborns in the first month of life. Early Hum Dev [Internet]. 2014;90(10):679–83. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2014.07.016 13. Krueger C. Exposure to maternal voice in preterm infants: A review. Adv Neonatal Care. 2010;10(1):13–8. 14. Filippa M, Devouche E, Arioni C, Imberty M, Gratier M. Live maternal speech and singing have beneficial effects on hospitalized preterm infants. Acta Paediatr Int J Paediatr. 2013;102(10):1017–20. 15.Provenzi L, Broso S, Montirosso R. Do mothers sound good? A systematic review of the effects of maternal voice exposure on preterm infants’ development. Neurosci Biobehav Rev [Internet]. 2018;88(January):42–50. Available from: https://doi.org/10.1016/j.neubiorev.2018.03.009 16. Williamson S, McGrath JM. What Are the Effects of the Maternal Voice on Preterm Infants in the NICU? Adv Neonatal Care. 2019;19(4):294–310. 17. Capilouto GJ, Cunningham TJ, Giannone PJ, Grider D. A comparison of the nutritive sucking performance of full-term and preterm neonates at hospital discharge: A prospective study. Early Hum Dev [Internet]. 2019;134(May):26–30. Available from: https://doi.org/10.1016/j.earlhumdev.2019.05.007 18. Lau C. Development of infant oral feeding skills: What do we know? Am J Clin Nutr. 2016;103(2):616S-621S. 19. Lau C. Development of suck and swallow mechanisms in infants. Ann Nutr Metab. 2015;66(0 5):7–14. 20. World Health Organization. Preterm birth [Internet]. Notas descriptivas. 2018. Available from: https://www.who.int/es/news-room/fact-sheets/detail/preterm-birth 21. Departamento Nacional de Estadística (DANE). Nacimientos 2019. 2019. 22. Stewart DL, Barfield WD. Updates on an at-risk population: Late-preterm and early-term infants. Pediatrics. 2019;144(5). 23. Engle WA, Tomashek KM, Wallman C, Stark AR, Adamkin DH, Batton DG, et al. “Late-preterm” infants: A population at risk. Pediatrics. 2007;120(6):1390–401. 24. Almadhoob A, Ohlsson A. Sound reduction management in the neonatal intensive care unit for preterm or very low birth weight infants. Cochrane Database Syst Rev. 2020;2020(1). 25. Brown G. NICU Noise and The Preterm Infant. Neonatal Netw. 2008;28(April):165–73. 26. Fumagalli M, Provenzi L, De Carli P, Dessimone F, Sirgiovanni I, Giorda R, et al. From early stress to 12-month development in very preterm infants: Preliminary findings on epigenetic mechanisms and brain growth. PLoS One. 2018;13(1):1–15. 27. Pados BF. Physiology of Stress and Use of Skin-to-Skin Care as a Stress-Reducing Intervention in the NICU. Nurs Women's Health [Internet]. 2019;23(1):59–70. Available from: https://doi.org/10.1016/j.nwh.2018.11.002 28. Hall RW, Anand KJS. Physiology of Pain and Stress in the Newborn. Neoreviews [Internet]. 2005 [cited 2023 Aug 31];6(2):e61–8. Available from: https://publications.aap.org/neoreviews/article-abstract/6/2/e61/88579/Physiology-of-Pain-and-Stress-in-the-Newborn?redirectedFrom=fulltex 29. Krueger C, Parker L, Chiu S-H, Theriaque D. Maternal Voice and Short-Term Outcomes in Preterm Infants. Dev Psychobiol [Internet]. 2010 [cited 2023 Aug 31];23(1):1–7. Available from: https://onlinelibrary.wiley.com/doi/10.1002/dev.20426 30. Ministerio de Salud y Protección Social. Guía de práctica clínica del recién nacido prematuro [Internet]. Vol. 2, Colciencias. 2013 [cited 2023 Aug 31]. 2–70 p. Available from: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/INEC/IETS/GPC_Completa_Premat.pdf 31. Sajjadian N, Mohammadzadeh M, Alizadeh Taheri P, Shariat M. Positive effects of low intensity recorded maternal voice on physiologic reactions in premature infants. Infant Behav Dev [Internet]. 2017;46:59–66. Available from: http://dx.doi.org/10.1016/j.infbeh.2016.11.009 32. Pallás Alonso CR. Cuidados centrados en el desarrollo en las unidades neonatales. An Pediatr Contin. 2014;12(2):62–7. 33. Ruiz E. Cuidados Centrados En El Neurodesarrollo Del Recién Nacido. Rev Enfermería CyL [Internet]. 2016;8:1–33. Available from: http://www.revistaenfermeriacyl.com/index.php/revistaenfermeriacyl/article/viewFile/177/148 34. Byers-Heinlein K. High-Amplitude Sucking Procedure. In: Brooks PJ, Kempe V, editors. Encyclopedia of Language Development. SAGE Publications, Inc.; 2014. p. 263–4. 35. Capilouto GJ, Cunningham TJ, Giannone PJ, Grider D. A comparison of the nutritive sucking performance of full-term and preterm neonates at hospital discharge: A prospective study. Early Hum Dev. 2019;134(May):26–30. 36. Haslbeck FB, Jakab A, Held U, Bassler D, Bucher H-U, Hagmann C. Creative music therapy to promote brain function and brain structure in preterm infants: A randomized controlled pilot study. NeuroImage Clin [Internet]. 2020;25:102171. Available from: http://www.sciencedirect.com/science/article/pii/S2213158220300103 37. Koelsch S. Brain correlates of music-evoked emotions. Nat Rev Neurosci [Internet]. 2014;15(3):170–80. Available from: http://dx.doi.org/10.1038/nrn3666 38. Koelsch S, Boehlig A, Hohenadel M, Nitsche I, Bauer K, Sack U. The impact of acute stress on hormones and cytokines, and how their recovery is affected by music-evoked positive mood. Sci Rep. 2016;6(September 2015):1–11. 39. Mendoza A, Claros D, Mendoza L, Arias M, Peñaranda C. Epidemiología de la prematuridad, sus determinantes y prevención del parto prematuro. Rev Chil Obstet Ginecol. 2016;81(4):330–42. 40. Therien JM, Worwa CT, Mattia FR, DeRegnier RAO. Altered pathways for auditory discrimination and recognition memory in preterm infants. Dev Med Child Neurol. 2004;46(12):816–24. 41. Smith SW, Ortmann AJ, Clark WW. Noise in the neonatal intensive care unit: a new approach to examining acoustic events. Noise Health [Internet]. 2018;20(95):121–30. Available from: https://www.noiseandhealth.org/article.asp?issn=1463-1741;year=2018;volume=20;issue=95;spage=121;epage=130;aulast=Smith 42. Lyngstad LT, Tandberg BS, Storm H, Ekeberg BL, Moen A. Does skin-to-skin contact reduce stress during diaper change in preterm infants? Early Hum Dev [Internet]. 2014;90(4):169–72. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2014.01.011 43. Mcmahon E, Wintermark P, Lahav A. Auditory brain development in premature infants: The importance of early experience. Ann N Y Acad Sci [Internet]. 2012 [cited 2023 Oct 14];1252(1):17–24. Available from: https://pubmed.ncbi.nlm.nih.gov/22524335/ 44. Chang E, Merzenich M. Environmental Noise Retards Auditory Cortical Development. Science (80- ). 2003;300(April):498–502. 45. Koeppen BM, Stanton BA. Berne y Levy: Fisiología. Séptima. Elsevier; 2018. 46. Cannizzaro C, Paladino M. Fisiología y fisiopatología de la adaptación neonatal. Anest Analg Reanim. 2011;24(2):59–74. 47. Hillman NH, Kallapur SG, Jobe AH. Physiology of transition from intrauterine to extrauterine life. Clin Perinatol. 2012;39(4):769–83. 48. Mulkey SB, Plessis A dú. The Critical Role of the Central Autonomic Nervous System in Fetal-Neonatal Transition. Semin Pediatr Neurol [Internet]. 2018;28:29–37. Available from: http://dx.doi.org/10.1016/j.spen.2018.05.004 49. Longin E, Gerstner T, Schaible T, Lenz T, König S. Maturation of the autonomic nervous system: Differences in heart rate variability in premature vs. term infants. J Perinat Med. 2006;34(4):303–8. 50. Boron W, Boulpaep E. Fisiología Médica. 3ra ed. 2017. 51. Hunt CE. Ontogeny of Autonomic Regulation in Late Preterm Infants Born at 34-37 Weeks Postmenstrual Age. Semin Perinatol. 2006;30(2):73–6. 52. Mulkey SB, du Plessis AJ. Autonomic nervous system development and its impact on neuropsychiatric outcome. Pediatr Res. 2019;85(2):120–6. 53. Cannon WB. Bodily changes in pain, hunger, fear, and rage : an account of recent researches into the function of emotional excitement. Second. New York, NY: D.Appleton and Company; 1929. 54. Brazelton T. Neonatal Behavioral Assesment Scale. London: Spastic International Medical Publications; 1973. 1–65 p. 55. Medoff‐Cooper B, Ray W. Neonatal Sucking Behaviors. Image J Nurs Scholarsh. 1995;27(3):195–200. 56. Lumeng JC, Weeks HM, Asta K, Sturza J, Kaciroti NA, Miller AL, et al. Sucking behavior in typical and challenging feedings in association with weight gain from birth to 4 Months in full-term infants: Sucking and Weight Gain in Infancy. Appetite [Internet]. 2020;153(July 2019):104745. Available from: https://doi.org/10.1016/j.appet.2020.104745 57. Modrell A, Tadi P. Primitive Reflexes [Internet]. StatPearls. 2021. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554606/ 58. Sohn M, Ahn Y, Lee S. Assessment of Primitive Reflexes in High-risk Newborns. J Clin Med Res. 2011;3(6):285–90. 59. Hall KD. Pediatric Dysphagia Resource Guide [Internet]. Singular Thomson Learning, editor. Singular Thomson Learning; 2001. Available from: https://books.google.com.co/books?id=pepsAAAAMAAJ 60. Boron W, Boulapaep E. Fisiología Médica. Tercera. Elsevier; 2017. 61. Bianchini P V, Montenegro HP. Motricidad orofacial: Fundamentos anatomofisiológicos y evolutivos para la evaluación clínica [Internet]. 2009. Available from: https://books.google.com.co/books?id=SsxgjwEACAAJ 62. Sampallo-Pedroza R. Neonatos y lactantes menores- Guía orofacial y deglutoria: Evaluación, diagnóstico e intervención terapéutica. Bogotá: Facultad de Medicina- Universidad Nacional de Colombia; 2015. 63. Katz PS. Evolution of central pattern generators and rhythmic behaviours. Philos Trans R Soc B Biol Sci. 2016;371(1685). 64. Samson N, Praud JP, Quenet B, Similowski T, Straus C. New insights into sucking, swallowing and breathing central generators: A complexity analysis of rhythmic motor behaviors. Neurosci Lett [Internet]. 2017;638:90–5. Available from: http://dx.doi.org/10.1016/j.neulet.2016.12.016 65. Barlow SM. Central pattern generation involved in oral and respiratory control for feeding in the term infant. Curr Opin Otolaryngol Head Neck Surg. 2009;17(3):187–93. 66. Iriki A, Nozaki S, Nakamura Y. Feeding behavior in mammals: corticobulbar projection is reorganized during conversion from sucking to chewing. Dev Brain Res. 1988;44(2):189–96. 67. Barlow SM, Estep M. Central pattern generation and the motor infrastructure for suck, respiration, and speech. J Commun Disord. 2006;39(5):366–80. 68. Muñoz-Ortiz J, Muñoz-Ortiz E, López-Meraz ML, Beltran-Parrazal L, Morgado-Valle C. Pre-Bötzinger complex: Generation and modulation of respiratory rhythm. Neurologia. 2019;34(7):461–8. 69. Barlow SM, Radder JPL, Radder ME, Radder AK. Central pattern generators for orofacial movements and speech. Handb Behav Neurosci. 2010;19(C):351–69. 70. Shandley S, Capilouto G, Tamilia E, Riley DM, Johnson YR, Papadelis C. Abnormal Nutritive Sucking as an Indicator of Neonatal Brain Injury. Front Pediatr. 2021;8(January):1–13. 71. Mistry S, Hamdy S. Neural Control of Feeding and Swallowing. Phys Med Rehabil Clin N Am [Internet]. 2008;19(4):709–28. Available from: http://dx.doi.org/10.1016/j.pmr.2008.05.002 72. Piontelli A, Ceriani F, Fabietti I, Fogliani R, Restelli E, Kustermann A. Swallowing, Sucking, and Mouthing BT - Development of Normal Fetal Movements: The Last 15 Weeks of Gestation. In: Piontelli A, editor. Milano: Springer Milan; 2015. p. 41–51. Available from: https://doi.org/10.1007/978-88-470-5373-1_5 73. Rendón M, Serrano G. Physiology of nutritive sucking in newborns and infants. Bol Med Hosp Infant Mex. 2011;68(4):319–27. 74. Lau C. Oral Feeding in the Preterm Infant. Neoreviews. 2006;7(1):e19–27. 75. Polin R, Fox W, Steven Abman. Fetal and Neonatal physiology. 4ta ed. Elsevier; 2011. 76. Guido-campuzano MA, Ibarra-reyes MP, Mateos-ortiz C, Mendoza-vásquez N. Eficacia de la succión no nutritiva en recién nacidos pretérmino. Perinatol y Reprod humana. 2012;26(3):198–207. 77. Foster J, Psaila K, Patterson T. Non-nutritive sucking for increasing physiologic stability and nutrition in preterm infants. Cochrane Database Syst Rev [Internet]. 2016; Available from: www.growthcharts.rcpch.ac.uk 78. Neiva FCB, Leone CR, Leone C, Siqueira LL, Uema KA, Evangelista D, et al. Non-nutritive sucking evaluation in preterm newborns and the start of oral feeding: A multicenter study. Clinics. 2014;69(6):393–7. 79. Pineda R, Dewey K, Jacobsen A, Smith J. Non-Nutritive Sucking in the Preterm Infant. Am J Perinatol. 2019;36(3):268–76. 80. Hogan N, Sternad D. Sensitivity of Smoothness Measures to Movement Duration, Amplitude and Arrests. J Mot Behav. 2009;41(6):529–34. 81. Balasubramanian S, Melendez-Calderon A, Roby-Brami A, Burdet E. On the analysis of movement smoothness. J Neuroeng Rehabil [Internet]. 2015;12(1):1–11. Available from: http://dx.doi.org/10.1186/s12984-015-0090-9 82. Vali P, Lakshminrusimha S. Oxyhemoglobin Saturation Targets in Newborns and the Role of Automated Oxygen Delivery Systems [Internet]. Updates on Neonatal Chronic Lung Disease. Elsevier Inc.; 2020. 207–223 p. Available from: http://dx.doi.org/10.1016/B978-0-323-68353-1.00014-2 83. Hyttel-Sorensen S, Pellicer A, Alderliesten T, Austin T, Van Bel F, Benders M, et al. Cerebral near infrared spectroscopy oximetry in extremely preterm infants: Phase II randomised clinical trial. BMJ. 2015;350(January):1–11. 84. Saliba S, Esseily R, Filippa M, Kuhn P, Gratier M. Exposure to human voices has beneficial effects on preterm infants in the neonatal intensive care unit. Acta Paediatr Int J Paediatr. 2018;107(7):1122–30. 85. Webb AR, Heller HT, Benson CB, Lahav A. Mother’s voice and heartbeat sounds elicit auditory plasticity in the human brain before full gestation. Proc Natl Acad Sci U S A. 2015;112(10):3152–7. 86. Carlier MEM, Harmony T. Development of auditory sensory memory in preterm infants. Early Hum Dev [Internet]. 2020;145:105045. Available from: http://www.sciencedirect.com/science/article/pii/S0378378219304360 87. Caskey M, Stephens B, Tucker R, Vohr B. Importance of parent talk on the development of preterm infant vocalizations. Vol. 128, Pediatrics. 2011. p. 910–6. 88. Caskey M, Stephens B, Tucker R, Vohr B. Adult talk in the NICU with preterm infants and developmental outcomes. Pediatrics. 2014;133(3). 89. Alexandre C, De Jonckheere J, Rakza T, Mur S, Carette D, Logier R, et al. Impact of cocooning and maternal voice on the autonomic nervous system activity in the premature newborn infant. Arch Pediatr. 2013;20(9):963–8. 90. Doheny L, Hurwitz S, Insoft R, Ringer S, Lahav A. Exposure to biological maternal sounds improves cardiorespiratory regulation in extremely preterm infants. J Matern Neonatal Med. 2012;25(9):1591–4. 91. Panagiotidis J, Lahav A. Simulation of prenatal maternal sounds in NICU incubators: A pilot safety and feasibility study. J Matern Neonatal Med. 2010;23(SUPPL. 3):106–9. 92. Zimmerman E, Keunen K, Norton M, Lahav A. Weight gain velocity in very low-birth-weight infants: Effects of exposure to biological maternal sounds. Am J Perinatol. 2013;30(10):863–70. 93. Butler SC, O’Sullivan LP, Shah BL, Berthier NE. Preference for infant-directed speech in preterm infants. Infant Behav Dev [Internet]. 2014;37(4):505–11. Available from: http://dx.doi.org/10.1016/j.infbeh.2014.06.007 94. Schaefer M, Hatcher RP, Barglow PD. Prematurity and infant stimulation: A review of research. Child Psychiatry Hum Dev. 1980;10(4):199–212. 95. Bozzette M. Healthy preterm infant responses to taped maternal voice. J Perinat Neonatal Nurs. 2008;22(4):307–16. 96. Johnston CC, Filion F, Nuyt AM. Recorded maternal voice for preterm neonates undergoing heel lance. Adv Neonatal Care. 2007;7(5):258–66. 97. Picciolini O, Porro M, Meazza A, Giannì ML, Rivoli C, Lucco G, et al. Early exposure to maternal voice: Effects on preterm infants development. Early Hum Dev [Internet]. 2014;90(6):287–92. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2014.03.003 98. Saito Y, Fukuhara R, Aoyama S, Toshima T. Frontal brain activation in premature infants’ response to auditory stimuli in neonatal intensive care unit. Early Hum Dev [Internet]. 2009;85(7):471–4. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2009.04.004 99. Nfant Labs. Clinical Evidence Guide [Internet]. 2019. Available from: www.nfant.com 100. Asociación Médica Mundial. Declaración de Helsinki de la AMM – Principios éticos para las investigaciones médicas en seres humanos. Helsinki; 1964. 101. Ministerio de Salud y Protección Social. Resolución 8430. 1993. 102. Woythaler M. Neurodevelopmental outcomes of the late preterm infant. Semin Fetal Neonatal Med [Internet]. 2019;24(1):54–9. Available from: https://www.sciencedirect.com/science/article/pii/S1744165X18301136 103. Capilouto GJ, Cunningham TJ. Objective assessment of a preterm infant’s nutritive sucking from initiation of feeding through hospitalization and discharge. Neonatal Intensive Care. 2016;29(1):40–5. 104. Capilouto GJ, Cunningham TJ, Mullineaux DR, Tamilia E, Papadelis C, Giannone PJ. Quantifying Neonatal Sucking Performance: Promise of New Methods. MCN Am J Matern Nurs. 2017;42(5):300. 105. Capilouto GJ, Cunningham T, Frederick E, Dupont-Versteegden E, Desai N, Butterfield TA. Comparison of tongue muscle characteristics of preterm and full-term infants during nutritive and nonnutritive sucking. Infant Behav Dev [Internet]. 2014;37(3):435–45. Available from: http://dx.doi.org/10.1016/j.infbeh.2014.05.010 106. Als H, Tronick E, Lester BM, Brazelton TB. The Brazelton Neonatal Behavioral Assesment Scale (BNBAS). J Abnorm Child Psychol. 1977;5(3):215–30. 107. Villamizar Carvajal B, Vargas Porras C, Díaz Martínez LA. El progreso de la alimentación oral del recién nacido prematuro. Salud UIS. 2010;42:262–70. 108. DiTomasso D, Cloud M. Systematic Review of Expected Weight Changes After Birth for Full-Term, Breastfed Newborns. JOGNN - J Obstet Gynecol Neonatal Nurs [Internet]. 2019;48(6):593–603. Available from: https://doi.org/10.1016/j.jogn.2019.09.004 109. Valentine GC, Umoren RA, Perez KM. Early inadequate or excessive weight loss: A potential contributor to mortality in premature newborns in resource-scarce settings? Pediatr Neonatol [Internet]. 2021;62(3):237–9. Available from: https://doi.org/10.1016/j.pedneo.2021.01.004 110. Adjerid K, Mayerl CJ, Gould FDH, Edmonds CE, Stricklen BM, Bond LE, et al. Does birth weight affect neonatal body weight, growth, and physiology in an animal model? PLoS One [Internet]. 2021;16:1–14. Available from: http://dx.doi.org/10.1371/journal.pone.0246954 111. Mayerl CJ, Gould FDH, Bond LE, Stricklen BM, Buddington RK, German RZ. Preterm birth disrupts the development of feeding and breathing coordination. J Appl Physiol. 2019;126(6):1681–6. 112. Dodds R, Denison HJ, Ntani G, Cooper R, Cooper C, Sayer AA, et al. Birth weight and muscle strength : a systematic review and meta- analysis. J Nutr Heal Aging. 2019;16(7):609–15. 113. Barr JG, Veena SR, Kiran KN, Wills AK, Winder NR, Kehoe S, et al. The relationship of birthweight, muscle size at birth and post-natal growth to grip strength in 9-year-old Indian children: Findings from the Mysore Parthenon study. J Dev Orig Health Dis. 2010;1(5):329–37. 114. Lahav A. Questionable sound exposure outside of the womb: Frequency analysis of environmental noise in the neonatal intensive care unit. Acta Paediatr Int J Paediatr. 2015;104(1):e14–9. 115. Lahav A, Skoe E. An acoustic gap between the NICU and womb: A potential risk for compromised neuroplasticity of the auditory system in preterm infants. Front Neurosci. 2014;8(DEC):1–8. 116. Šrámková H, Granqvist S, Herbst CT, Švec JG. The softest sound levels of the human voice in normal subjects. J Acoust Soc Am [Internet]. 2015;137(1):407–18. Available from: http://dx.doi.org/10.1121/1.4904538 117. Leino T, Laukkanen AM, Ilomäki I, Mäki E. Assessment of vocal capacity of Finnish university students. Folia Phoniatr Logop. 2008;60(4):199–209. 118. Gramming P. Vocal loudness and frequency capabilities of the voice. J Voice. 1991;5(2):144–57. 119. Sanchez K, Oates J, Dacakis G, Holmberg EB. Speech and voice range profiles of adults with untrained normal voices: Methodological implications. Logop Phoniatr Vocology. 2014;39(2):62–71. 120. Gholami N, Borimnejad L, Jafari R, Rasouli M, Ranjbar F. Effect of a noise reduction program on stress of premature neonates in neonatal intensive care unit. J Neonatal Nurs [Internet]. 2023;29(1):194–8. Available from: https://www.sciencedirect.com/science/article/pii/S1355184122000989 121. Smith S, Ortmann A, Clark W. Noise in the Neonatal Intensive Care Unit: A New Approach to Examining Acoustica Events. Noise Heal. 2018;20(95):121–30. 122. Wachman EM, Lahav A. The effects of noise on preterm infants in the NICU. Arch Dis Child Fetal Neonatal Ed. 2011;96(4). 123. Anand KJS, Scalzo FM. Can Adverse Neonatal Experiences Alter Brain Development and Subsequent Behavior? Biol Neonate [Internet]. 2000 Feb 7;77(2):69–82. Available from: https://doi.org/10.1159/000014197 124. Zimmerman E, Lahav A. Ototoxicity in preterm infants: Effects of genetics, aminoglycosides, and loud environmental noise. J Perinatol [Internet]. 2013;33(1):3–8. Available from: http://dx.doi.org/10.1038/jp.2012.105 125. Scheydt S, Müller Staub M, Frauenfelder F, Nielsen GH, Behrens J, Needham I. Sensory overload: A concept analysis. Int J Ment Health Nurs. 2017;26(2):110–20. 126. Philpott-Robinson K, Lane SJ, Korostenski L, Lane AE. The impact of the Neonatal Intensive Care Unit on sensory and developmental outcomes in infants born preterm: A scoping review. Br J Occup Ther. 2017;80(8):459–69. 127. Ryckman J, Hilton C, Rogers C, Pineda R. Sensory processing disorder in preterm infants during early childhood and relationships to early neurobehavior. Early Hum Dev. 2017;113:18–22. 128. Crozier SC, Goodson JZ, Mackay ML, Synnes AR, Grunau RE, Miller SP, et al. Sensory Processing Patterns in Children Born Very Preterm. Am J Occup Ther [Internet]. 2015 Dec 18;70(1):7001220050p1–7. Available from: https://doi.org/10.5014/ajot.2016.018747 129. Chorna O, Solomon JE, Slaughter JC, Stark AR, Maitre NL. Abnormal sensory reactivity in preterm infants during the first year correlates with adverse neurodevelopmental outcomes at 2 years of age. Arch Dis Child Fetal Neonatal Ed. 2014;99(6):F475–9. 130. Yiallourou SR, Witcombe NB, Sands SA, Walker AM, Horne RSC. The development of autonomic cardiovascular control is altered by preterm birth. Early Hum Dev [Internet]. 2013;89(3):145–52. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2012.09.009 131. Rand K, Lahav A. Impact of the NICU environment on language deprivation in preterm infants. Acta Paediatr Int J Paediatr. 2014;103(3):243–8. 132. Korja R, Latva R, Lehtonen L. The effects of preterm birth on mother-infant interaction and attachment during the infant’s first two years. Acta Obstet Gynecol Scand. 2012;91(2):164–73. 133. Schmücker G, Brisch KH, Köhntop B, Betzler S, Österle M, Pohlandt F, et al. The influence of prematurity, maternal anxiety, and infants’ neurobiological risk on mother-infant interactions. Infant Ment Health J. 2005;26(5):423–41. 134. Alkozei A, McMahon E, Lahav A. Stress levels and depressive symptoms in NICU mothers in the early postpartum period. J Matern Neonatal Med. 2014;27(17):1738–43. 135. Ionio C, Colombo C, Brazzoduro V, Mascheroni E, Confalonieri E, Castoldi F, et al. Mothers and fathers in nicu: The impact of preterm birth on parental distress. Eur J Psychol. 2016;12(4):604–21. 136. Bieleninik Ł, Lutkiewicz K, Cieślak M, Preis-Orlikowska J, Bidzan M. Associations of maternal-infant bonding with maternal mental health, infant’s characteristics and socio-demographical variables in the early postpartum period: A cross-sectional study. Int J Environ Res Public Health. 2021;18(16):1–19. 137. Hofer MA. Early relationships as regulators of infant physiology and behavior. Acta Paediatr Suppl. 1994;397(8):9–18. 138. Carvalho MES, Justo JMRM, Gratier M, Tomé T, Pereira E, Rodrigues H. Vocal responsiveness of preterm infants to maternal infant-directed speaking and singing during skin-to-skin contact (Kangaroo Care) in the NICU. Infant Behav Dev. 2019;57(August). 139. Ionio C, Lista G, Mascheroni E, Olivari MG, Confalonieri E, Mastrangelo M, et al. Premature birth: complexities and difficulties in building the mother–child relationship. J Reprod Infant Psychol [Internet]. 2017;35(5):509–23. Available from: http://doi.org/10.1080/02646838.2017.1383977 140. Gatta M, Miscioscia M, Svanellini L, Peraro C, Simonelli A. A psychological perspective on preterm children: The influence of contextual factors on quality of family interactions. Biomed Res Int. 2017;2017. 141. Hoffenkamp HN, Tooten A, Hall RAS, Croon MA, Braeken J, Winkel FW, et al. The impact of premature childbirth on parental bonding. Evol Psychol. 2012;10(3):542–61. 142. Joaquim RHVT, Wernet M, Leite AM, Fonseca LMM, Mello DF de. Interações Entre Mães E Bebês Prematuros: Enfoque Nas Necessidades Essenciais. Cad Bras Ter Ocup. 2018;26(3):580–9. 143. Floccia C, Nazzi T, Bertoncini J. Unfamiliar voice discrimination for short stimuli in newborns. Dev Sci. 2000;3(3):333–43. 144. Mira A, Coo S, Lemp RB, González R. Interactions between mothers and their moderate preterm babies during hospitalization. Andes Pediatr. 2022;93(6):889–97. 145. Taheri L, Jahromi MK, Abbasi M, Hojat M. Effect of recorded male lullaby on physiologic response of neonates in NICU. Appl Nurs Res [Internet]. 2017;33:127–30. Available from: http://dx.doi.org/10.1016/j.apnr.2016.11.003 146. Chorna OD, Slaughter JC, Wang L, Stark AR, Maitre NL. A pacifier-activated music player with mother’s voice improves oral feeding in preterm infants. Pediatrics. 2014;133(3):462–8. 147. Krueger C, Horesh E, Crossland BA. Safe Sound Exposure in the Fetus and Preterm Infant. JOGNN - J Obstet Gynecol Neonatal Nurs. 2012;41(2):166–70. 148. Fischel JE. The organization of human newborn sucking and movement during auditory stimulation. Infant Behav Dev. 1982;5(1):45–61. 149. Floccia C, Christophe A, Bertoncini J. High-Amplitude Sucking and Newborns: The Quest for Underlying Mechanisms. J Exp Child Psychol. 1997;64(2):175–98. 150. Asociación Colombiana de Neonatología (ASCON). Criterios de Ingreso y Egreso a las Unidades de Recién Naciodos en Colombia. 2020. 151. Arrieta-Arrieta A, Herrera-Malambo D, Díaz-Vargas LC, Pérez-Yepes C, Dueñas-Castell C, Flórez-Tanus A, et al. Determinantes de la estancia prolongada de neonatos en una Unidad de Cuidados Intensivos. Rev Ceincias la Salud. 2019;17(2). 152. Reisenzein R, Meyer WU, Niepel M. Surprise. Encycl Hum Behav Second Ed. 2012;564–70. 153. Sameroff AJ. Changes in the nonnutritive sucking response to stimulation during infancy. J Exp Child Psychol. 1970;10(1):112–9. |
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Atribución-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Sampallo Pedroza, Rosa Mercedesd133b6c0838bb76b56d3735463a78162Zuluaga, Jairo Alberto7037d9953df9d277735965e071b7c70bLamprea Rodríguez, Sandra Milenaa47e5a7909c24446241af37f17eb875bVoz, Habla y DegluciónLamprea Rodríguez, Sandra Milena [0000000248845761]2024-10-25T17:19:29Z2024-10-25T17:19:29Z2024https://repositorio.unal.edu.co/handle/unal/87066Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramas, fotografías, tablasUn neonato pretérmino, definido como aquel que nace antes de la semana 37 de gestación, requiere de cuidados especializados en las Unidades de Cuidado Intensivo Neonatal (UCIN) debido a su inmadurez. El ambiente en la UCIN, cualitativa y cuantitativamente diferente al útero, puede generar niveles de estrés altos en los neonatos, afectando su estabilidad clínica. Teorías del neurodesarrollo sugieren la creación de intervenciones dentro de la UCIN que favorezcan la estabilidad clínica y el desarrollo del neonato, como la exposición a la voz materna y el uso de la succión no nutritiva, para contrarrestar los efectos nocivos del estrés. Esta investigación tiene como objetivo evaluar los cambios fisiológicos en el patrón de succión no nutritiva y en la saturación de oxígeno enmarcados dentro del proceso succión:deglución:respiración ante la exposición de la voz materna en vivo. Se realizó un estudio cuasiexperimental con 9 neonatos pretérmino tardíos por 4 días consecutivos, con dos condiciones: exposición a la voz materna en vivo y no exposición. Resultados: Aunque no se encontraron diferencias significativas entre la condición de voz y no voz para las variables medidas, se observaron diferencias en función del día. Se realizaron análisis descriptivos y complementarios de covarianza. Discusión y conclusiones: Se discuten los posibles mecanismos fisiológicos y otros factores que pudieron llevar a la ausencia de diferencias en la condición de exposición a la voz materna. La conclusión destaca que el estudio fisiológico del proceso succión:deglución:respiración es multifactorial y debe abordarse con diseños que tengan en cuenta la complejidad del fenómeno (Texto tomado de la fuente).A preterm newborn, defined as one born before the 37th week of gestation, requires specialized care in Neonatal Intensive Care Units (NICUs) due to their immaturity. The NICU environment, qualitatively and quantitatively different from the uterus, can generate high levels of stress in neonates, affecting their clinical stability. Neurodevelopmental Theories suggest the implementation of interventions within the NICU that promote clinical stability and neonatal development, such as exposure to maternal voice and the use of non-nutritive sucking, to counteract the detrimental effects of stress. This research aims to evaluate physiological changes in the non-nutritive sucking pattern and oxygen saturation framed within the sucking:swallowing:breathing process during exposure to live maternal voice. A quasi-experimental study was conducted with 9 late preterm neonates over 4 consecutive days, with two conditions: exposure to live maternal voice and no exposure. Results: Although no significant differences were found between the voice and no-voice conditions for the measured variables, differences were observed based on the day. Descriptive and complementary covariate analyses were performed. Discussion and Conclusions: Possible physiological mechanisms and other factors that could have led to the absence of differences in exposure to maternal voice are discussed. The conclusion emphasizes that the physiological study of the sucking:swallowing:breathing process is multifactorial and should be approached with designs that consider the complexity of the phenomenon.MaestríaMagíster en FisiologíaEstudio de diseño cuasiexperimental con medidas repetidas, contrabalanceado por 4 días seguidos. Muestreo: A conveniencia, 11 neonatos pretérmino hospitalizados en la UCIN de la Clínica del Occidente junto con sus madres.xv, 148 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Maestría en FisiologíaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y salud::612 - Fisiología humana610 - Medicina y salud::618 - Ginecología, obstetricia, pediatría, geriatríaRecien Nacido PrematuroUnidades de Cuidado Intensivo NeonatalTrastornos del NeurodesarrolloConducta en la LactanciaDegluciónInfant, PrematureIntensive Care, NeonatalNeurodevelopmental DisordersSucking BehaviorDeglutitionNeonato pretérminoVoz maternaPatrón de succiónSaturación de oxígenoNeurodesarrolloNeurodevelopmentPreterm newbornMaternal voiceSucking patternOxygen saturationFisiología del proceso succión:deglución:respiración durante exposición a la voz materna de neonatos pretérmino en la unidad de cuidado intensivo neonatalPhysiology of the sucking:swallowing:breathing process during exposure to maternal voice in preterm neonates in the neonatal intensive care unitTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TM1. World Health Organization. Born Too Soon: The global action report on preterm birth. 2012.2. McCormick MC, Litt JS, Smith VC, Zupancic JAF. Prematurity: An overview and public health implications. Annu Rev Public Health. 2011;32:367–79.3. Lubbe W, van der Walt C, Klopper H. NICU environment - What should it be like? J Neonatal Nurs. 2012;18(3):90–3.4. Bremmer P, Byers JF, Kiehl E. Noise and the premature infant: physiological effects and practice implications. J Obstet Gynecol Neonatal Nurs. 2003;32(4):447–54.5. Acevedo DH, Becerra JIR, Martínez ÁL. The philosophy of the developmental centred care of the premature infant (NIDCAP): A literature review. Enferm Glob. 2017;16(4):577–602.6. Maltese A, Gallai B, Marotta R, Lavano F, Lavano S, Tripi G, et al. The synactive theory of development: The keyword for neurodevelopmental disorders. Acta Medica Mediterr [Internet]. 2017;33(June):393–8. Available from: https://www.ncbi.nlm.nih.gov/pubmed/263504247. Mooney-Leber SM, Brummelte S. Neonatal pain and reduced maternal care: Early-life stressors interacting to impact brain and behavioral development. Neuroscience [Internet]. 2017;342:21–36. Available from: http://www.sciencedirect.com/science/article/pii/S03064522163014038. Bucsea O, Pillai Riddell R. Non-pharmacological pain management in the neonatal intensive care unit: Managing neonatal pain without drugs. Semin Fetal Neonatal Med [Internet]. 2019;24(4):101017. Available from: https://doi.org/10.1016/j.siny.2019.05.0099. Basch K. Beiträge zur Kenntniss des menschlichen Milchapparats. Arch Gynakol [Internet]. 1893;44(1):15–54. Available from: https://doi.org/10.1007/BF0198117910. Tamilia E, Taffoni F, Formica D, Ricci L, Schena E, Keller F, et al. Technological solutions and main indices for the assessment of newborns’ Nutritive Sucking: A review. Sensors (Switzerland). 2014;14(1):634–58.11. Tamilia E, Formica D, Scaini A, Taffoni F. An Automated System for the Analysis of Newborns’ Oral-Motor Behavior. IEEE Trans Neural Syst Rehabil Eng. 2016;24(12):1294–303.12. Rand K, Lahav A. Maternal sounds elicit lower heart rate in preterm newborns in the first month of life. Early Hum Dev [Internet]. 2014;90(10):679–83. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2014.07.01613. Krueger C. Exposure to maternal voice in preterm infants: A review. Adv Neonatal Care. 2010;10(1):13–8.14. Filippa M, Devouche E, Arioni C, Imberty M, Gratier M. Live maternal speech and singing have beneficial effects on hospitalized preterm infants. Acta Paediatr Int J Paediatr. 2013;102(10):1017–20.15.Provenzi L, Broso S, Montirosso R. Do mothers sound good? A systematic review of the effects of maternal voice exposure on preterm infants’ development. Neurosci Biobehav Rev [Internet]. 2018;88(January):42–50. Available from: https://doi.org/10.1016/j.neubiorev.2018.03.00916. Williamson S, McGrath JM. What Are the Effects of the Maternal Voice on Preterm Infants in the NICU? Adv Neonatal Care. 2019;19(4):294–310.17. Capilouto GJ, Cunningham TJ, Giannone PJ, Grider D. A comparison of the nutritive sucking performance of full-term and preterm neonates at hospital discharge: A prospective study. Early Hum Dev [Internet]. 2019;134(May):26–30. Available from: https://doi.org/10.1016/j.earlhumdev.2019.05.00718. Lau C. Development of infant oral feeding skills: What do we know? Am J Clin Nutr. 2016;103(2):616S-621S.19. Lau C. Development of suck and swallow mechanisms in infants. Ann Nutr Metab. 2015;66(0 5):7–14.20. World Health Organization. Preterm birth [Internet]. Notas descriptivas. 2018. Available from: https://www.who.int/es/news-room/fact-sheets/detail/preterm-birth21. Departamento Nacional de Estadística (DANE). Nacimientos 2019. 2019.22. Stewart DL, Barfield WD. Updates on an at-risk population: Late-preterm and early-term infants. Pediatrics. 2019;144(5).23. Engle WA, Tomashek KM, Wallman C, Stark AR, Adamkin DH, Batton DG, et al. “Late-preterm” infants: A population at risk. Pediatrics. 2007;120(6):1390–401.24. Almadhoob A, Ohlsson A. Sound reduction management in the neonatal intensive care unit for preterm or very low birth weight infants. Cochrane Database Syst Rev. 2020;2020(1).25. Brown G. NICU Noise and The Preterm Infant. Neonatal Netw. 2008;28(April):165–73.26. Fumagalli M, Provenzi L, De Carli P, Dessimone F, Sirgiovanni I, Giorda R, et al. From early stress to 12-month development in very preterm infants: Preliminary findings on epigenetic mechanisms and brain growth. PLoS One. 2018;13(1):1–15.27. Pados BF. Physiology of Stress and Use of Skin-to-Skin Care as a Stress-Reducing Intervention in the NICU. Nurs Women's Health [Internet]. 2019;23(1):59–70. Available from: https://doi.org/10.1016/j.nwh.2018.11.00228. Hall RW, Anand KJS. Physiology of Pain and Stress in the Newborn. Neoreviews [Internet]. 2005 [cited 2023 Aug 31];6(2):e61–8. Available from: https://publications.aap.org/neoreviews/article-abstract/6/2/e61/88579/Physiology-of-Pain-and-Stress-in-the-Newborn?redirectedFrom=fulltex29. Krueger C, Parker L, Chiu S-H, Theriaque D. Maternal Voice and Short-Term Outcomes in Preterm Infants. Dev Psychobiol [Internet]. 2010 [cited 2023 Aug 31];23(1):1–7. Available from: https://onlinelibrary.wiley.com/doi/10.1002/dev.2042630. Ministerio de Salud y Protección Social. Guía de práctica clínica del recién nacido prematuro [Internet]. Vol. 2, Colciencias. 2013 [cited 2023 Aug 31]. 2–70 p. Available from: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/INEC/IETS/GPC_Completa_Premat.pdf31. Sajjadian N, Mohammadzadeh M, Alizadeh Taheri P, Shariat M. Positive effects of low intensity recorded maternal voice on physiologic reactions in premature infants. Infant Behav Dev [Internet]. 2017;46:59–66. Available from: http://dx.doi.org/10.1016/j.infbeh.2016.11.00932. Pallás Alonso CR. Cuidados centrados en el desarrollo en las unidades neonatales. An Pediatr Contin. 2014;12(2):62–7.33. Ruiz E. Cuidados Centrados En El Neurodesarrollo Del Recién Nacido. Rev Enfermería CyL [Internet]. 2016;8:1–33. Available from: http://www.revistaenfermeriacyl.com/index.php/revistaenfermeriacyl/article/viewFile/177/14834. Byers-Heinlein K. High-Amplitude Sucking Procedure. In: Brooks PJ, Kempe V, editors. Encyclopedia of Language Development. SAGE Publications, Inc.; 2014. p. 263–4.35. Capilouto GJ, Cunningham TJ, Giannone PJ, Grider D. A comparison of the nutritive sucking performance of full-term and preterm neonates at hospital discharge: A prospective study. Early Hum Dev. 2019;134(May):26–30.36. Haslbeck FB, Jakab A, Held U, Bassler D, Bucher H-U, Hagmann C. Creative music therapy to promote brain function and brain structure in preterm infants: A randomized controlled pilot study. NeuroImage Clin [Internet]. 2020;25:102171. Available from: http://www.sciencedirect.com/science/article/pii/S221315822030010337. Koelsch S. Brain correlates of music-evoked emotions. Nat Rev Neurosci [Internet]. 2014;15(3):170–80. Available from: http://dx.doi.org/10.1038/nrn366638. Koelsch S, Boehlig A, Hohenadel M, Nitsche I, Bauer K, Sack U. The impact of acute stress on hormones and cytokines, and how their recovery is affected by music-evoked positive mood. Sci Rep. 2016;6(September 2015):1–11.39. Mendoza A, Claros D, Mendoza L, Arias M, Peñaranda C. Epidemiología de la prematuridad, sus determinantes y prevención del parto prematuro. Rev Chil Obstet Ginecol. 2016;81(4):330–42.40. Therien JM, Worwa CT, Mattia FR, DeRegnier RAO. Altered pathways for auditory discrimination and recognition memory in preterm infants. Dev Med Child Neurol. 2004;46(12):816–24.41. Smith SW, Ortmann AJ, Clark WW. Noise in the neonatal intensive care unit: a new approach to examining acoustic events. Noise Health [Internet]. 2018;20(95):121–30. Available from: https://www.noiseandhealth.org/article.asp?issn=1463-1741;year=2018;volume=20;issue=95;spage=121;epage=130;aulast=Smith42. Lyngstad LT, Tandberg BS, Storm H, Ekeberg BL, Moen A. Does skin-to-skin contact reduce stress during diaper change in preterm infants? Early Hum Dev [Internet]. 2014;90(4):169–72. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2014.01.01143. Mcmahon E, Wintermark P, Lahav A. Auditory brain development in premature infants: The importance of early experience. Ann N Y Acad Sci [Internet]. 2012 [cited 2023 Oct 14];1252(1):17–24. Available from: https://pubmed.ncbi.nlm.nih.gov/22524335/44. Chang E, Merzenich M. Environmental Noise Retards Auditory Cortical Development. Science (80- ). 2003;300(April):498–502.45. Koeppen BM, Stanton BA. Berne y Levy: Fisiología. Séptima. Elsevier; 2018.46. Cannizzaro C, Paladino M. Fisiología y fisiopatología de la adaptación neonatal. Anest Analg Reanim. 2011;24(2):59–74.47. Hillman NH, Kallapur SG, Jobe AH. Physiology of transition from intrauterine to extrauterine life. Clin Perinatol. 2012;39(4):769–83.48. Mulkey SB, Plessis A dú. The Critical Role of the Central Autonomic Nervous System in Fetal-Neonatal Transition. Semin Pediatr Neurol [Internet]. 2018;28:29–37. Available from: http://dx.doi.org/10.1016/j.spen.2018.05.00449. Longin E, Gerstner T, Schaible T, Lenz T, König S. Maturation of the autonomic nervous system: Differences in heart rate variability in premature vs. term infants. J Perinat Med. 2006;34(4):303–8.50. Boron W, Boulpaep E. Fisiología Médica. 3ra ed. 2017.51. Hunt CE. Ontogeny of Autonomic Regulation in Late Preterm Infants Born at 34-37 Weeks Postmenstrual Age. Semin Perinatol. 2006;30(2):73–6.52. Mulkey SB, du Plessis AJ. Autonomic nervous system development and its impact on neuropsychiatric outcome. Pediatr Res. 2019;85(2):120–6.53. Cannon WB. Bodily changes in pain, hunger, fear, and rage : an account of recent researches into the function of emotional excitement. Second. New York, NY: D.Appleton and Company; 1929.54. Brazelton T. Neonatal Behavioral Assesment Scale. London: Spastic International Medical Publications; 1973. 1–65 p.55. Medoff‐Cooper B, Ray W. Neonatal Sucking Behaviors. Image J Nurs Scholarsh. 1995;27(3):195–200.56. Lumeng JC, Weeks HM, Asta K, Sturza J, Kaciroti NA, Miller AL, et al. Sucking behavior in typical and challenging feedings in association with weight gain from birth to 4 Months in full-term infants: Sucking and Weight Gain in Infancy. Appetite [Internet]. 2020;153(July 2019):104745. Available from: https://doi.org/10.1016/j.appet.2020.10474557. Modrell A, Tadi P. Primitive Reflexes [Internet]. StatPearls. 2021. Available from: https://www.ncbi.nlm.nih.gov/books/NBK554606/58. Sohn M, Ahn Y, Lee S. Assessment of Primitive Reflexes in High-risk Newborns. J Clin Med Res. 2011;3(6):285–90.59. Hall KD. Pediatric Dysphagia Resource Guide [Internet]. Singular Thomson Learning, editor. Singular Thomson Learning; 2001. Available from: https://books.google.com.co/books?id=pepsAAAAMAAJ60. Boron W, Boulapaep E. Fisiología Médica. Tercera. Elsevier; 2017.61. Bianchini P V, Montenegro HP. Motricidad orofacial: Fundamentos anatomofisiológicos y evolutivos para la evaluación clínica [Internet]. 2009. Available from: https://books.google.com.co/books?id=SsxgjwEACAAJ62. Sampallo-Pedroza R. Neonatos y lactantes menores- Guía orofacial y deglutoria: Evaluación, diagnóstico e intervención terapéutica. Bogotá: Facultad de Medicina- Universidad Nacional de Colombia; 2015.63. Katz PS. Evolution of central pattern generators and rhythmic behaviours. Philos Trans R Soc B Biol Sci. 2016;371(1685).64. Samson N, Praud JP, Quenet B, Similowski T, Straus C. New insights into sucking, swallowing and breathing central generators: A complexity analysis of rhythmic motor behaviors. Neurosci Lett [Internet]. 2017;638:90–5. Available from: http://dx.doi.org/10.1016/j.neulet.2016.12.01665. Barlow SM. Central pattern generation involved in oral and respiratory control for feeding in the term infant. Curr Opin Otolaryngol Head Neck Surg. 2009;17(3):187–93.66. Iriki A, Nozaki S, Nakamura Y. Feeding behavior in mammals: corticobulbar projection is reorganized during conversion from sucking to chewing. Dev Brain Res. 1988;44(2):189–96.67. Barlow SM, Estep M. Central pattern generation and the motor infrastructure for suck, respiration, and speech. J Commun Disord. 2006;39(5):366–80.68. Muñoz-Ortiz J, Muñoz-Ortiz E, López-Meraz ML, Beltran-Parrazal L, Morgado-Valle C. Pre-Bötzinger complex: Generation and modulation of respiratory rhythm. Neurologia. 2019;34(7):461–8.69. Barlow SM, Radder JPL, Radder ME, Radder AK. Central pattern generators for orofacial movements and speech. Handb Behav Neurosci. 2010;19(C):351–69.70. Shandley S, Capilouto G, Tamilia E, Riley DM, Johnson YR, Papadelis C. Abnormal Nutritive Sucking as an Indicator of Neonatal Brain Injury. Front Pediatr. 2021;8(January):1–13.71. Mistry S, Hamdy S. Neural Control of Feeding and Swallowing. Phys Med Rehabil Clin N Am [Internet]. 2008;19(4):709–28. Available from: http://dx.doi.org/10.1016/j.pmr.2008.05.00272. Piontelli A, Ceriani F, Fabietti I, Fogliani R, Restelli E, Kustermann A. Swallowing, Sucking, and Mouthing BT - Development of Normal Fetal Movements: The Last 15 Weeks of Gestation. In: Piontelli A, editor. Milano: Springer Milan; 2015. p. 41–51. Available from: https://doi.org/10.1007/978-88-470-5373-1_573. Rendón M, Serrano G. Physiology of nutritive sucking in newborns and infants. Bol Med Hosp Infant Mex. 2011;68(4):319–27.74. Lau C. Oral Feeding in the Preterm Infant. Neoreviews. 2006;7(1):e19–27.75. Polin R, Fox W, Steven Abman. Fetal and Neonatal physiology. 4ta ed. Elsevier; 2011.76. Guido-campuzano MA, Ibarra-reyes MP, Mateos-ortiz C, Mendoza-vásquez N. Eficacia de la succión no nutritiva en recién nacidos pretérmino. Perinatol y Reprod humana. 2012;26(3):198–207.77. Foster J, Psaila K, Patterson T. Non-nutritive sucking for increasing physiologic stability and nutrition in preterm infants. Cochrane Database Syst Rev [Internet]. 2016; Available from: www.growthcharts.rcpch.ac.uk78. Neiva FCB, Leone CR, Leone C, Siqueira LL, Uema KA, Evangelista D, et al. Non-nutritive sucking evaluation in preterm newborns and the start of oral feeding: A multicenter study. Clinics. 2014;69(6):393–7.79. Pineda R, Dewey K, Jacobsen A, Smith J. Non-Nutritive Sucking in the Preterm Infant. Am J Perinatol. 2019;36(3):268–76.80. Hogan N, Sternad D. Sensitivity of Smoothness Measures to Movement Duration, Amplitude and Arrests. J Mot Behav. 2009;41(6):529–34.81. Balasubramanian S, Melendez-Calderon A, Roby-Brami A, Burdet E. On the analysis of movement smoothness. J Neuroeng Rehabil [Internet]. 2015;12(1):1–11. Available from: http://dx.doi.org/10.1186/s12984-015-0090-982. Vali P, Lakshminrusimha S. Oxyhemoglobin Saturation Targets in Newborns and the Role of Automated Oxygen Delivery Systems [Internet]. Updates on Neonatal Chronic Lung Disease. Elsevier Inc.; 2020. 207–223 p. Available from: http://dx.doi.org/10.1016/B978-0-323-68353-1.00014-283. Hyttel-Sorensen S, Pellicer A, Alderliesten T, Austin T, Van Bel F, Benders M, et al. Cerebral near infrared spectroscopy oximetry in extremely preterm infants: Phase II randomised clinical trial. BMJ. 2015;350(January):1–11.84. Saliba S, Esseily R, Filippa M, Kuhn P, Gratier M. Exposure to human voices has beneficial effects on preterm infants in the neonatal intensive care unit. Acta Paediatr Int J Paediatr. 2018;107(7):1122–30.85. Webb AR, Heller HT, Benson CB, Lahav A. Mother’s voice and heartbeat sounds elicit auditory plasticity in the human brain before full gestation. Proc Natl Acad Sci U S A. 2015;112(10):3152–7.86. Carlier MEM, Harmony T. Development of auditory sensory memory in preterm infants. Early Hum Dev [Internet]. 2020;145:105045. Available from: http://www.sciencedirect.com/science/article/pii/S037837821930436087. Caskey M, Stephens B, Tucker R, Vohr B. Importance of parent talk on the development of preterm infant vocalizations. Vol. 128, Pediatrics. 2011. p. 910–6.88. Caskey M, Stephens B, Tucker R, Vohr B. Adult talk in the NICU with preterm infants and developmental outcomes. Pediatrics. 2014;133(3).89. Alexandre C, De Jonckheere J, Rakza T, Mur S, Carette D, Logier R, et al. Impact of cocooning and maternal voice on the autonomic nervous system activity in the premature newborn infant. Arch Pediatr. 2013;20(9):963–8.90. Doheny L, Hurwitz S, Insoft R, Ringer S, Lahav A. Exposure to biological maternal sounds improves cardiorespiratory regulation in extremely preterm infants. J Matern Neonatal Med. 2012;25(9):1591–4.91. Panagiotidis J, Lahav A. Simulation of prenatal maternal sounds in NICU incubators: A pilot safety and feasibility study. J Matern Neonatal Med. 2010;23(SUPPL. 3):106–9.92. Zimmerman E, Keunen K, Norton M, Lahav A. Weight gain velocity in very low-birth-weight infants: Effects of exposure to biological maternal sounds. Am J Perinatol. 2013;30(10):863–70.93. Butler SC, O’Sullivan LP, Shah BL, Berthier NE. Preference for infant-directed speech in preterm infants. Infant Behav Dev [Internet]. 2014;37(4):505–11. Available from: http://dx.doi.org/10.1016/j.infbeh.2014.06.00794. Schaefer M, Hatcher RP, Barglow PD. Prematurity and infant stimulation: A review of research. Child Psychiatry Hum Dev. 1980;10(4):199–212.95. Bozzette M. Healthy preterm infant responses to taped maternal voice. J Perinat Neonatal Nurs. 2008;22(4):307–16.96. Johnston CC, Filion F, Nuyt AM. Recorded maternal voice for preterm neonates undergoing heel lance. Adv Neonatal Care. 2007;7(5):258–66.97. Picciolini O, Porro M, Meazza A, Giannì ML, Rivoli C, Lucco G, et al. Early exposure to maternal voice: Effects on preterm infants development. Early Hum Dev [Internet]. 2014;90(6):287–92. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2014.03.00398. Saito Y, Fukuhara R, Aoyama S, Toshima T. Frontal brain activation in premature infants’ response to auditory stimuli in neonatal intensive care unit. Early Hum Dev [Internet]. 2009;85(7):471–4. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2009.04.00499. Nfant Labs. Clinical Evidence Guide [Internet]. 2019. Available from: www.nfant.com100. Asociación Médica Mundial. Declaración de Helsinki de la AMM – Principios éticos para las investigaciones médicas en seres humanos. Helsinki; 1964.101. Ministerio de Salud y Protección Social. Resolución 8430. 1993.102. Woythaler M. Neurodevelopmental outcomes of the late preterm infant. Semin Fetal Neonatal Med [Internet]. 2019;24(1):54–9. Available from: https://www.sciencedirect.com/science/article/pii/S1744165X18301136103. Capilouto GJ, Cunningham TJ. Objective assessment of a preterm infant’s nutritive sucking from initiation of feeding through hospitalization and discharge. Neonatal Intensive Care. 2016;29(1):40–5.104. Capilouto GJ, Cunningham TJ, Mullineaux DR, Tamilia E, Papadelis C, Giannone PJ. Quantifying Neonatal Sucking Performance: Promise of New Methods. MCN Am J Matern Nurs. 2017;42(5):300.105. Capilouto GJ, Cunningham T, Frederick E, Dupont-Versteegden E, Desai N, Butterfield TA. Comparison of tongue muscle characteristics of preterm and full-term infants during nutritive and nonnutritive sucking. Infant Behav Dev [Internet]. 2014;37(3):435–45. Available from: http://dx.doi.org/10.1016/j.infbeh.2014.05.010106. Als H, Tronick E, Lester BM, Brazelton TB. The Brazelton Neonatal Behavioral Assesment Scale (BNBAS). J Abnorm Child Psychol. 1977;5(3):215–30.107. Villamizar Carvajal B, Vargas Porras C, Díaz Martínez LA. El progreso de la alimentación oral del recién nacido prematuro. Salud UIS. 2010;42:262–70.108. DiTomasso D, Cloud M. Systematic Review of Expected Weight Changes After Birth for Full-Term, Breastfed Newborns. JOGNN - J Obstet Gynecol Neonatal Nurs [Internet]. 2019;48(6):593–603. Available from: https://doi.org/10.1016/j.jogn.2019.09.004109. Valentine GC, Umoren RA, Perez KM. Early inadequate or excessive weight loss: A potential contributor to mortality in premature newborns in resource-scarce settings? Pediatr Neonatol [Internet]. 2021;62(3):237–9. Available from: https://doi.org/10.1016/j.pedneo.2021.01.004110. Adjerid K, Mayerl CJ, Gould FDH, Edmonds CE, Stricklen BM, Bond LE, et al. Does birth weight affect neonatal body weight, growth, and physiology in an animal model? PLoS One [Internet]. 2021;16:1–14. Available from: http://dx.doi.org/10.1371/journal.pone.0246954111. Mayerl CJ, Gould FDH, Bond LE, Stricklen BM, Buddington RK, German RZ. Preterm birth disrupts the development of feeding and breathing coordination. J Appl Physiol. 2019;126(6):1681–6.112. Dodds R, Denison HJ, Ntani G, Cooper R, Cooper C, Sayer AA, et al. Birth weight and muscle strength : a systematic review and meta- analysis. J Nutr Heal Aging. 2019;16(7):609–15.113. Barr JG, Veena SR, Kiran KN, Wills AK, Winder NR, Kehoe S, et al. The relationship of birthweight, muscle size at birth and post-natal growth to grip strength in 9-year-old Indian children: Findings from the Mysore Parthenon study. J Dev Orig Health Dis. 2010;1(5):329–37.114. Lahav A. Questionable sound exposure outside of the womb: Frequency analysis of environmental noise in the neonatal intensive care unit. Acta Paediatr Int J Paediatr. 2015;104(1):e14–9.115. Lahav A, Skoe E. An acoustic gap between the NICU and womb: A potential risk for compromised neuroplasticity of the auditory system in preterm infants. Front Neurosci. 2014;8(DEC):1–8.116. Šrámková H, Granqvist S, Herbst CT, Švec JG. The softest sound levels of the human voice in normal subjects. J Acoust Soc Am [Internet]. 2015;137(1):407–18. Available from: http://dx.doi.org/10.1121/1.4904538117. Leino T, Laukkanen AM, Ilomäki I, Mäki E. Assessment of vocal capacity of Finnish university students. Folia Phoniatr Logop. 2008;60(4):199–209.118. Gramming P. Vocal loudness and frequency capabilities of the voice. J Voice. 1991;5(2):144–57.119. Sanchez K, Oates J, Dacakis G, Holmberg EB. Speech and voice range profiles of adults with untrained normal voices: Methodological implications. Logop Phoniatr Vocology. 2014;39(2):62–71.120. Gholami N, Borimnejad L, Jafari R, Rasouli M, Ranjbar F. Effect of a noise reduction program on stress of premature neonates in neonatal intensive care unit. J Neonatal Nurs [Internet]. 2023;29(1):194–8. Available from: https://www.sciencedirect.com/science/article/pii/S1355184122000989121. Smith S, Ortmann A, Clark W. Noise in the Neonatal Intensive Care Unit: A New Approach to Examining Acoustica Events. Noise Heal. 2018;20(95):121–30.122. Wachman EM, Lahav A. The effects of noise on preterm infants in the NICU. Arch Dis Child Fetal Neonatal Ed. 2011;96(4).123. Anand KJS, Scalzo FM. Can Adverse Neonatal Experiences Alter Brain Development and Subsequent Behavior? Biol Neonate [Internet]. 2000 Feb 7;77(2):69–82. Available from: https://doi.org/10.1159/000014197124. Zimmerman E, Lahav A. Ototoxicity in preterm infants: Effects of genetics, aminoglycosides, and loud environmental noise. J Perinatol [Internet]. 2013;33(1):3–8. Available from: http://dx.doi.org/10.1038/jp.2012.105125. Scheydt S, Müller Staub M, Frauenfelder F, Nielsen GH, Behrens J, Needham I. Sensory overload: A concept analysis. Int J Ment Health Nurs. 2017;26(2):110–20.126. Philpott-Robinson K, Lane SJ, Korostenski L, Lane AE. The impact of the Neonatal Intensive Care Unit on sensory and developmental outcomes in infants born preterm: A scoping review. Br J Occup Ther. 2017;80(8):459–69.127. Ryckman J, Hilton C, Rogers C, Pineda R. Sensory processing disorder in preterm infants during early childhood and relationships to early neurobehavior. Early Hum Dev. 2017;113:18–22.128. Crozier SC, Goodson JZ, Mackay ML, Synnes AR, Grunau RE, Miller SP, et al. Sensory Processing Patterns in Children Born Very Preterm. Am J Occup Ther [Internet]. 2015 Dec 18;70(1):7001220050p1–7. Available from: https://doi.org/10.5014/ajot.2016.018747129. Chorna O, Solomon JE, Slaughter JC, Stark AR, Maitre NL. Abnormal sensory reactivity in preterm infants during the first year correlates with adverse neurodevelopmental outcomes at 2 years of age. Arch Dis Child Fetal Neonatal Ed. 2014;99(6):F475–9.130. Yiallourou SR, Witcombe NB, Sands SA, Walker AM, Horne RSC. The development of autonomic cardiovascular control is altered by preterm birth. Early Hum Dev [Internet]. 2013;89(3):145–52. Available from: http://dx.doi.org/10.1016/j.earlhumdev.2012.09.009131. Rand K, Lahav A. Impact of the NICU environment on language deprivation in preterm infants. Acta Paediatr Int J Paediatr. 2014;103(3):243–8.132. Korja R, Latva R, Lehtonen L. The effects of preterm birth on mother-infant interaction and attachment during the infant’s first two years. Acta Obstet Gynecol Scand. 2012;91(2):164–73.133. Schmücker G, Brisch KH, Köhntop B, Betzler S, Österle M, Pohlandt F, et al. The influence of prematurity, maternal anxiety, and infants’ neurobiological risk on mother-infant interactions. Infant Ment Health J. 2005;26(5):423–41.134. Alkozei A, McMahon E, Lahav A. Stress levels and depressive symptoms in NICU mothers in the early postpartum period. J Matern Neonatal Med. 2014;27(17):1738–43.135. Ionio C, Colombo C, Brazzoduro V, Mascheroni E, Confalonieri E, Castoldi F, et al. Mothers and fathers in nicu: The impact of preterm birth on parental distress. Eur J Psychol. 2016;12(4):604–21.136. Bieleninik Ł, Lutkiewicz K, Cieślak M, Preis-Orlikowska J, Bidzan M. Associations of maternal-infant bonding with maternal mental health, infant’s characteristics and socio-demographical variables in the early postpartum period: A cross-sectional study. Int J Environ Res Public Health. 2021;18(16):1–19.137. Hofer MA. Early relationships as regulators of infant physiology and behavior. Acta Paediatr Suppl. 1994;397(8):9–18.138. Carvalho MES, Justo JMRM, Gratier M, Tomé T, Pereira E, Rodrigues H. Vocal responsiveness of preterm infants to maternal infant-directed speaking and singing during skin-to-skin contact (Kangaroo Care) in the NICU. Infant Behav Dev. 2019;57(August).139. Ionio C, Lista G, Mascheroni E, Olivari MG, Confalonieri E, Mastrangelo M, et al. Premature birth: complexities and difficulties in building the mother–child relationship. J Reprod Infant Psychol [Internet]. 2017;35(5):509–23. Available from: http://doi.org/10.1080/02646838.2017.1383977140. Gatta M, Miscioscia M, Svanellini L, Peraro C, Simonelli A. A psychological perspective on preterm children: The influence of contextual factors on quality of family interactions. Biomed Res Int. 2017;2017.141. Hoffenkamp HN, Tooten A, Hall RAS, Croon MA, Braeken J, Winkel FW, et al. The impact of premature childbirth on parental bonding. Evol Psychol. 2012;10(3):542–61.142. Joaquim RHVT, Wernet M, Leite AM, Fonseca LMM, Mello DF de. Interações Entre Mães E Bebês Prematuros: Enfoque Nas Necessidades Essenciais. Cad Bras Ter Ocup. 2018;26(3):580–9.143. Floccia C, Nazzi T, Bertoncini J. Unfamiliar voice discrimination for short stimuli in newborns. Dev Sci. 2000;3(3):333–43.144. Mira A, Coo S, Lemp RB, González R. Interactions between mothers and their moderate preterm babies during hospitalization. Andes Pediatr. 2022;93(6):889–97.145. Taheri L, Jahromi MK, Abbasi M, Hojat M. Effect of recorded male lullaby on physiologic response of neonates in NICU. Appl Nurs Res [Internet]. 2017;33:127–30. Available from: http://dx.doi.org/10.1016/j.apnr.2016.11.003146. Chorna OD, Slaughter JC, Wang L, Stark AR, Maitre NL. A pacifier-activated music player with mother’s voice improves oral feeding in preterm infants. Pediatrics. 2014;133(3):462–8.147. Krueger C, Horesh E, Crossland BA. Safe Sound Exposure in the Fetus and Preterm Infant. JOGNN - J Obstet Gynecol Neonatal Nurs. 2012;41(2):166–70.148. Fischel JE. The organization of human newborn sucking and movement during auditory stimulation. Infant Behav Dev. 1982;5(1):45–61.149. Floccia C, Christophe A, Bertoncini J. High-Amplitude Sucking and Newborns: The Quest for Underlying Mechanisms. J Exp Child Psychol. 1997;64(2):175–98.150. Asociación Colombiana de Neonatología (ASCON). Criterios de Ingreso y Egreso a las Unidades de Recién Naciodos en Colombia. 2020.151. Arrieta-Arrieta A, Herrera-Malambo D, Díaz-Vargas LC, Pérez-Yepes C, Dueñas-Castell C, Flórez-Tanus A, et al. Determinantes de la estancia prolongada de neonatos en una Unidad de Cuidados Intensivos. Rev Ceincias la Salud. 2019;17(2).152. Reisenzein R, Meyer WU, Niepel M. Surprise. Encycl Hum Behav Second Ed. 2012;564–70.153. Sameroff AJ. Changes in the nonnutritive sucking response to stimulation during infancy. 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