Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético

ilustraciones (principalmente a color), diagramas, mapas

Autores:
Flórez Bautista, Bayron Germán
Tipo de recurso:
Fecha de publicación:
2024
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/86364
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/86364
https://repositorio.unal.edu.co/
Palabra clave:
540 - Química y ciencias afines::542 - Técnicas, procedimientos, aparatos, equipos, materiales
660 - Ingeniería química::668 - Tecnología de otros productos orgánicos
Cosmética
Cosmeticos
Beauty culture
Cosmetics
Microencapsulación
Aceite de cannabis
Coalescencia
Potencial Z
Emulsión
Cosméticos
Microencapsulation
Cannabis oil
Coalescence
Z Potential
Emulsion
Cosmetics
Aceite de cannabis
Cannabis oil
Rights
openAccess
License
Atribución-NoComercial-SinDerivadas 4.0 Internacional
id UNACIONAL2_e270f454bc0c5bf206bfd52956769cd1
oai_identifier_str oai:repositorio.unal.edu.co:unal/86364
network_acronym_str UNACIONAL2
network_name_str Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético
dc.title.translated.eng.fl_str_mv Encapsulation of cannabis oil for use as an active ingredient in cosmetic consumer products
title Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético
spellingShingle Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético
540 - Química y ciencias afines::542 - Técnicas, procedimientos, aparatos, equipos, materiales
660 - Ingeniería química::668 - Tecnología de otros productos orgánicos
Cosmética
Cosmeticos
Beauty culture
Cosmetics
Microencapsulación
Aceite de cannabis
Coalescencia
Potencial Z
Emulsión
Cosméticos
Microencapsulation
Cannabis oil
Coalescence
Z Potential
Emulsion
Cosmetics
Aceite de cannabis
Cannabis oil
title_short Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético
title_full Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético
title_fullStr Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético
title_full_unstemmed Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético
title_sort Encapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosmético
dc.creator.fl_str_mv Flórez Bautista, Bayron Germán
dc.contributor.advisor.none.fl_str_mv Rodríguez Niño, Gerardo
dc.contributor.author.none.fl_str_mv Flórez Bautista, Bayron Germán
dc.contributor.researchgroup.spa.fl_str_mv Grupo de Investigación en Procesos Químicos y Bioquímicos
dc.subject.ddc.spa.fl_str_mv 540 - Química y ciencias afines::542 - Técnicas, procedimientos, aparatos, equipos, materiales
660 - Ingeniería química::668 - Tecnología de otros productos orgánicos
topic 540 - Química y ciencias afines::542 - Técnicas, procedimientos, aparatos, equipos, materiales
660 - Ingeniería química::668 - Tecnología de otros productos orgánicos
Cosmética
Cosmeticos
Beauty culture
Cosmetics
Microencapsulación
Aceite de cannabis
Coalescencia
Potencial Z
Emulsión
Cosméticos
Microencapsulation
Cannabis oil
Coalescence
Z Potential
Emulsion
Cosmetics
Aceite de cannabis
Cannabis oil
dc.subject.lemb.spa.fl_str_mv Cosmética
Cosmeticos
dc.subject.lemb.eng.fl_str_mv Beauty culture
Cosmetics
dc.subject.proposal.spa.fl_str_mv Microencapsulación
Aceite de cannabis
Coalescencia
Potencial Z
Emulsión
Cosméticos
dc.subject.proposal.eng.fl_str_mv Microencapsulation
Cannabis oil
Coalescence
Z Potential
Emulsion
Cosmetics
dc.subject.umls.spa.fl_str_mv Aceite de cannabis
dc.subject.umls.eng.fl_str_mv Cannabis oil
description ilustraciones (principalmente a color), diagramas, mapas
publishDate 2024
dc.date.accessioned.none.fl_str_mv 2024-07-03T00:03:36Z
dc.date.available.none.fl_str_mv 2024-07-03T00:03:36Z
dc.date.issued.none.fl_str_mv 2024
dc.type.spa.fl_str_mv Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.coarversion.spa.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.content.spa.fl_str_mv Text
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/TM
status_str publishedVersion
dc.identifier.uri.none.fl_str_mv https://repositorio.unal.edu.co/handle/unal/86364
dc.identifier.instname.spa.fl_str_mv Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv https://repositorio.unal.edu.co/
url https://repositorio.unal.edu.co/handle/unal/86364
https://repositorio.unal.edu.co/
identifier_str_mv Universidad Nacional de Colombia
Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv spa
language spa
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spelling Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Rodríguez Niño, Gerardocc3b4036a9c5c30dd1f98cb2b8b858c3600Flórez Bautista, Bayron Germán520843b1b1275af25c85a37e75543f8aGrupo de Investigación en Procesos Químicos y Bioquímicos2024-07-03T00:03:36Z2024-07-03T00:03:36Z2024https://repositorio.unal.edu.co/handle/unal/86364Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones (principalmente a color), diagramas, mapasEl aceite de cannabis debido a la presencia de cannabinoides, terpenoides y flavonoides presenta funciones activas y de valor nutricional o en tratamientos para la epilepsia, manejo del dolor, inflamación y desordenes neurodegenerativos. Debido a la variedad de las propiedades físicas de sus compuestos, esta puede presentar diferentes retos a la hora de su integración como ingrediente activo en productos. Entre estos se relacionan impactos de en el perfil olfativo, impacto en la estabilizas del producto y modificaciones o pérdida de metabolitos deseados. A modo de presentar un abordaje para enfrentar estos retos, se propone la encapsulación del aceite como una metodología que permite cubrir estos frentes. Para este abordaje, se hace un primer acercamiento alrededor de la contextualización de la planta de cannabis, sus compuestos, mercado actual de su extracto y su uso en diferentes productos en el mercado reciente. Posteriormente se aborda los mecanismos de encapsulación, sus principios y el desarrollo de tres diferentes rutas para su obtención. Realizado este contexto, se selecciona la coalescencia como mecanismo de encapsulamiento debido principalmente a su acceso tecnológico y de insumos. Así mismo, debido a la falta de bibliografía de la encapsulación del aceite bajo esta metodología y materiales encapsulantes, se diseña el proceso por medio de la revisión bibliográfica de este en otras aplicaciones. A partir de esto, se obtienen partículas de un tamaño medio de 9,43μm que posteriormente son caracterizadas por medio de la medición de su potencial Z en diferentes medios de pH, análisis termogravimétrico y la presentación de su morfología por medio de microscopia electrónica de barrido. A través de estos análisis se pudo identificar la encapsulación del aceite, así como la estabilidad de estas en un medio dado para la aplicación cosmética planteada. En torno a su aplicación cosmética, se evalúo el impacto a tres diferentes concentraciones (0.15%, 0.20% y 0,25%) dentro de la formulación emulsionada cosmética. Esta estabilidad se desarrolla sometiendo al producto en un ambiente de 45°C en horno y corroborando por medio cualitativo tras su centrifugación la no separación de fases a lo largo del mes de evaluación. Finalmente, se encontró la metodología capaz de formar partículas que proveen la protección y asilamiento del aceite, igualmente, que cargas superficiales pueden favorecer la estabilidad de los sistemas emulsionados (Texto tomado de la fuente).Cannabis oil, due to the presence of cannabinoids, terpenoids and flavonoids, has active functions and nutritional value or in treatments for epilepsy, pain management, inflammation, and neurodegenerative disorders. Due to the variety of physical properties of its compounds, it can present different challenges related with its integration as an active ingredient in products. These include impacts on the olfactory profile, impact on the stability of the product and modifications or loss of desired metabolites. To present an approach to face these challenges, oil encapsulation is proposed as a methodology that allows these fronts to be covered. For this approach, at first, it has made the contextualization of the cannabis plant, its compounds, current market for its extract and its use in different products in the recent market. Subsequently, the encapsulation mechanisms, their principles, and the development of three different routes to obtain them. Once this context is realized, coalescence is selected as an encapsulation mechanism mainly due to its technological and input access. Likewise, due to the lack of bibliography on oil encapsulation under this methodology and encapsulating materials, the process is designed through a bibliographic review of it in other applications. From this, particles with an average size of 9.43 μm are obtained, which are subsequently characterized by measuring their Z potential in different pH media, thermogravimetric analysis, and the presentation of their morphology by scanning electron microscopy. Through these analyzes it was possible to identify the encapsulation of the oil, as well as its stability in a specific medium for the proposed cosmetic application. Regarding its cosmetic application, the impact was evaluated at three different concentrations (0.15%, 0.20% and 0.25%) within the cosmetic emulsified formulation. This stability is developed by subjecting the product to an environment of 45°C in an oven and corroborating by qualitative means after centrifugation the non-separation of phases throughout the month of evaluation. Finally, the methodology was found capable of forming particles that provide protection and isolation of the oil, likewise, that surface charges can favor the stability of the emulsified systems (Texto tomado de la fuente).MaestríaMagíster en Ingeniería - Ingeniería QuímicaDiseño de ProductoIngeniería Química y Ambiental.Sede Bogotáxx, 105 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Ingeniería - Maestría en Ingeniería - Ingeniería QuímicaFacultad de IngenieríaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá540 - Química y ciencias afines::542 - Técnicas, procedimientos, aparatos, equipos, materiales660 - Ingeniería química::668 - Tecnología de otros productos orgánicosCosméticaCosmeticosBeauty cultureCosmeticsMicroencapsulaciónAceite de cannabisCoalescenciaPotencial ZEmulsiónCosméticosMicroencapsulationCannabis oilCoalescenceZ PotentialEmulsionCosmeticsAceite de cannabisCannabis oilEncapsulamiento de aceite de cannabis para uso como ingrediente activo en productos de consumo cosméticoEncapsulation of cannabis oil for use as an active ingredient in cosmetic consumer productsTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/TMAbe, A., Aggarwal, S. 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Springer New York. https://doi.org/10.1007/978-1-4419-1008-0/COVERBibliotecariosEstudiantesInvestigadoresMaestrosPúblico generalLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/86364/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINAL1016073601.2024.pdf1016073601.2024.pdfTesis de Maestría en Ingeniería Química - Encapsulamiento de Aceite de Cannabisapplication/pdf5524367https://repositorio.unal.edu.co/bitstream/unal/86364/2/1016073601.2024.pdf6938098b7b36c46fc16fafe458c3b141MD52THUMBNAIL1016073601.2024.pdf.jpg1016073601.2024.pdf.jpgGenerated Thumbnailimage/jpeg5712https://repositorio.unal.edu.co/bitstream/unal/86364/3/1016073601.2024.pdf.jpge2e853ced6268abd2ae3711716deb66bMD53unal/86364oai:repositorio.unal.edu.co:unal/863642024-07-02 23:05:02.81Repositorio Institucional Universidad Nacional de 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