Histopathology image classification via characterization of nuclei arrangement

Abstract. The automatic characterization of histopathology images is an important requirement for the development of computarized tools that might benefit clinicians in their everyday professional workflow. Researchers have developed image descriptors for histopathology images that are mainly migrated from the techniques used with natural images, which result in high-dimensional feature vectors that are difficult to interpret. Since automatic analysis of histopathology images is performed only as support tools for physicians, the level of interpretability of such automatic analysis is of considerable importance. This thesis work was focused in finding a way towards the characterization of histopathology images through the abstraction of simple histological concepts, i.e. information from cell properties. More specifically, we have investigated the potential of cells' area and topology for the construction of descriptors for histopathology images. Experimental results suggest that our proposed descriptors provide a discriminative power that could be used either for classification or retrieval tasks.

• Autores: Álvarez Corrales, Pablo Arturo
• Fecha de publicación: 2017
• Institución: Universidad Nacional de Colombia
• Repositorio: Universidad Nacional de Colombia
• Idioma: spa
• OAI Identifier: oai:repositorio.unal.edu.co:unal/60276
• Acceso en línea: https://repositorio.unal.edu.co/handle/unal/60276; http://bdigital.unal.edu.co/58542/
• Palabra clave: 57 Ciencias de la vida; Biología / Life sciences; biology; 61 Ciencias médicas; Medicina / Medicine and health; 62 Ingeniería y operaciones afines / Engineering; Virtual Microscopy; Image Characterization; Digital Pathology; Histopathology; Microscopía Virtual; Caracterización de Imagen; Patología Digital; Histopatología
• Rights: openAccess
• License: Atribución-NoComercial 4.0 Internacional