Epidemiological analysis of the incidence and resolution of the infection by the human papillomavirus in women undergoing a retrospective follow-up study

There are few longitudinal studies in Colombia that cover people from different parts of the country to allow understanding the infection dynamics by Human Papilloma Virus (HPV). A representative sample of 1433 women from three Colombian cities aged 18-60 years which were visited every 6 ± 2 months...

Full description

Autores:
Vega Ruiz, Erika Gilma
Sánchez, Ricardo
Lozano, José Manuel
Tipo de recurso:
Article of journal
Fecha de publicación:
2013
Institución:
Universidad Nacional de Colombia
Repositorio:
Universidad Nacional de Colombia
Idioma:
spa
OAI Identifier:
oai:repositorio.unal.edu.co:unal/49331
Acceso en línea:
https://repositorio.unal.edu.co/handle/unal/49331
http://bdigital.unal.edu.co/42788/
http://bdigital.unal.edu.co/42788/2/
Palabra clave:
VPH
incidencia
resolución de la infección
regresión de la lesión
persistencia
tasa
HPV
incidence
infection clearance
lesion regression
persistence
rate
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional
Description
Summary:There are few longitudinal studies in Colombia that cover people from different parts of the country to allow understanding the infection dynamics by Human Papilloma Virus (HPV). A representative sample of 1433 women from three Colombian cities aged 18-60 years which were visited every 6 ± 2 months during two years, were submitted to the Papanicolau and reaction Polymerase chain (pcr) tests. Infection incidence was 2.49 /1000 women/day (CI 95%, 2.25-2.75), the incidence rate for lesion was 0.043 lesion/1000 women/day (CI 95%, 0.021-0.086), while for infection clearance the rate was 2.47 infection clearance/1000 women/day (CI 95%, 2.25-2.71). A women´s subgroup who reported having lesions on the first visit, had a rate of 3.92 lesion-regressions/1000 women/day (CI 95%, 2.97-5.17). From a group of 619 women with infection, 27% reported a persistent infection and only 10% of 55 women with cervical lesion kept this condition. Data showed that incidence and infection resolution was frequent, while the epidemiological study of lesions would require a greater number of women and a cohort of longer duration.