Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer

Resumen Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer El funcionamiento de la personalidad determina aspectos emocionales, cognitivos y comportamentales en los individuos. A partir de esta noción, hallar la compleja interrelación entre algunos ras...

Full description

Autores:: Herrera Leiva, Lucas Mateo

Tipo de recurso:: Trabajo de grado de pregrado

Fecha de publicación:: 2024

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:: spa

id	UNACIONAL2_d2d6d4550ce3740815d636ad8f649c2c
oai_identifier_str	oai:repositorio.unal.edu.co:unal/85563
network_acronym_str	UNACIONAL2
network_name_str	Universidad Nacional de Colombia
repository_id_str
dc.title.spa.fl_str_mv	Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer
dc.title.translated.eng.fl_str_mv	Personality traits and their association with symptoms of anxiety and depression in cancer patients.
title	Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer
spellingShingle	Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer 610 - Medicina y salud::616 - Enfermedades 610 - Medicina y salud::613 - Salud y seguridad personal Trastornos de la personalidad Trastornos de ansiedad Trastorno depresivo Personality disorders Anxiety disorders Depressive disorder Enfermos con cáncer - Salud mental Cancer - Patients - Mental health Rasgos de personalidad Síntomas de ansiedad Síntomas de depresión Paciente con cáncer Personality traits Anxiety symptoms Depression symptoms Cancer patient
title_short	Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer
title_full	Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer
title_fullStr	Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer
title_full_unstemmed	Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer
title_sort	Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer
dc.creator.fl_str_mv	Herrera Leiva, Lucas Mateo
dc.contributor.advisor.spa.fl_str_mv	Urrego Mendoza, Diana Zulima Sánchez Pedraza, Ricardo
dc.contributor.author.spa.fl_str_mv	Herrera Leiva, Lucas Mateo
dc.subject.ddc.spa.fl_str_mv	610 - Medicina y salud::616 - Enfermedades 610 - Medicina y salud::613 - Salud y seguridad personal
topic	610 - Medicina y salud::616 - Enfermedades 610 - Medicina y salud::613 - Salud y seguridad personal Trastornos de la personalidad Trastornos de ansiedad Trastorno depresivo Personality disorders Anxiety disorders Depressive disorder Enfermos con cáncer - Salud mental Cancer - Patients - Mental health Rasgos de personalidad Síntomas de ansiedad Síntomas de depresión Paciente con cáncer Personality traits Anxiety symptoms Depression symptoms Cancer patient
dc.subject.decs.spa.fl_str_mv	Trastornos de la personalidad Trastornos de ansiedad Trastorno depresivo
dc.subject.decs.eng.fl_str_mv	Personality disorders Anxiety disorders Depressive disorder
dc.subject.lemb.spa.fl_str_mv	Enfermos con cáncer - Salud mental
dc.subject.lemb.eng.fl_str_mv	Cancer - Patients - Mental health
dc.subject.proposal.spa.fl_str_mv	Rasgos de personalidad Síntomas de ansiedad Síntomas de depresión Paciente con cáncer
dc.subject.proposal.eng.fl_str_mv	Personality traits Anxiety symptoms Depression symptoms Cancer patient
description	Resumen Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer El funcionamiento de la personalidad determina aspectos emocionales, cognitivos y comportamentales en los individuos. A partir de esta noción, hallar la compleja interrelación entre algunos rasgos de personalidad y los síntomas de depresión y ansiedad ha representado una fuente de interés significativo en la psiquiatría, de acuerdo con la comorbilidad y las consecuencias de estos fenómenos en términos de diagnóstico, tratamiento y pronóstico. A tal punto que se ha planteado, a raíz de ciertas presentaciones clínicas, un continuum entre algunos grupos de personalidad y síntomas afectivos, sin definir este hecho de manera concluyente. Con base en esto, se han realizado múltiples estudios que buscan asociación entre los rasgos de personalidad y los síntomas de ansiedad y depresión, que diluciden la importancia de este vínculo y que contribuyan al desarrollo de la práctica clínica. Objetivo: determinar la asociación entre los rasgos de personalidad y los síntomas de ansiedad y depresión en pacientes con cáncer del Instituto Nacional de Cancerología durante los años 2021 y 2022. Metodología: estudio observacional analítico, de corte transversal, el cual incluyó 399 pacientes del Instituto Nacional de Cancerología que se encuentren en fase de tratamiento de alguna enfermedad neoplásica, abordadas en los servicios que atienden los tipos de cáncer más frecuentes, mayores de 18 años que aceptaron hacer parte del estudio; a quienes se les aplicaron dos tipos de cuestionarios (Test de Salamanca y DASS-21), en busca de hallar la posible correlación entre los rasgos de personalidad y los síntomas de ansiedad y depresión. Resultados: estos pacientes tuvieron una edad promedio de 58 años (DE=13.9), en la mayoría de los casos fueron mujeres (69.4%; N=277). La configuración de personalidad más prevalente en este estudio fue la anancástica con 229 pacientes con estos rasgos (57.39%; IC95%: 54.39% a 60.39%), seguida de la histriónica, en la que se identificaron 157 pacientes con estos rasgos (39.35% (IC 95: 36.35% a 42.35%)) y, de manera relevante, los rasgos de personalidad esquizoide reconocidos en 149 pacientes (37.34%; (IC: 95: 34.34% a 40.33%)). En cuanto a los síntomas de depresión, en primer lugar se encontró la presentación moderada (10.03%, N=40), seguida de la leve (9.77%, N=39), la muy grave (6.52%, N=26) y finalmente la presentación grave (5.26%, N=21); y sobre los síntomas de ansiedad primero se tuvo en cuenta la presentación moderada (15.54%, N=62), seguida de la presentación muy grave (10.28%, N=41), luego la leve (9.02%, N=36) y al final la grave (4.51%, N=18). El análisis multivariado agrupó tres factores, el principal determina la asociación entre rasgos de personalidad y síntomas de depresión y ansiedad, con un hallazgo en particular de ausencia de rasgos de personalidad en correlación con la ausencia de síntomas de ansiedad y depresión. Palabras clave: rasgos de personalidad, síntomas de ansiedad, síntomas de depresión, paciente con cáncer. (Texto tomado de la fuente)
publishDate	2024
dc.date.accessioned.none.fl_str_mv	2024-01-31T17:03:32Z
dc.date.available.none.fl_str_mv	2024-01-31T17:03:32Z
dc.date.issued.none.fl_str_mv	2024
dc.type.spa.fl_str_mv	Trabajo de grado - Especialidad Médica
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/bachelorThesis
dc.type.version.spa.fl_str_mv	info:eu-repo/semantics/acceptedVersion
dc.type.coar.spa.fl_str_mv	http://purl.org/coar/resource_type/c_7a1f
dc.type.content.spa.fl_str_mv	Text
dc.type.redcol.spa.fl_str_mv	http://purl.org/redcol/resource_type/TP
format	http://purl.org/coar/resource_type/c_7a1f
status_str	acceptedVersion
dc.identifier.uri.none.fl_str_mv	https://repositorio.unal.edu.co/handle/unal/85563
dc.identifier.instname.spa.fl_str_mv	Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv	https://repositorio.unal.edu.co/
url	https://repositorio.unal.edu.co/handle/unal/85563 https://repositorio.unal.edu.co/
identifier_str_mv	Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv	spa
language	spa
dc.relation.references.spa.fl_str_mv	Adams, M. J., Howard, D. M., Luciano, M., Clarke, T. K., Davies, G., Hill, W. D., Smith, D., Deary, I. J., Porteous, D. J. & McIntosh, A. M. (2019, 2 octubre). Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition. Psychological Medicine, 50(15), 2526-2535. https://doi.org/10.1017/s0033291719002629 Akiskal, H. S. (1983, 1 julio). The Relationship of Personality to Affective Disorders. Archives of General Psychiatry, 40(7), 801. https://doi.org/10.1001/archpsyc.1983.01790060099013 Alagizy, H. A., Soltan, M. E., Soliman, S., Hegazy, N. N., & Gohar, S. (2020). Anxiety, depression and perceived stress among breast cancer patients: Single Institute experience. Middle East Current Psychiatry, 27(1). https://doi.org/10.1186/s43045-020-00036-x Améndola, L., Weary, D. & Zobel, G. (2022, octubre). Effects of personality on assessments of anxiety and cognition. Neuroscience & Biobehavioral Reviews, 141, 104827. https://doi.org/10.1016/j.neubiorev.2022.104827 Antoni, M. H., Lutgendorf, S. K., Cole, S. W., Dhabhar, F. S., Sephton, S. E., McDonald, P. G., Stefanek, M. & Sood, A. K. (2006). The influence of bio-behavioural factors on tumour biology: pathways and mechanisms. Nature Reviews Cancer, 6(3), 240-248. https://doi.org/10.1038/nrc1820 Bagby, R. M., Ryder, A. G. & Cristi, C. (2002, julio). Psychosocial and clinical predictorsof response to pharmacotherapy for depression. Journal of Psychiatry and Neuroscience, 4(27), 250-257. Barlow, D. H., Ellard, K. K., Sauer-Zavala, S., Bullis, J. R. & Carl, J. R. (2014, septiembre). The Origins of Neuroticism. Perspectives on Psychological Science, 9(5), 481-496. https://doi.org/10.1177/1745691614544528 Bennasar, R. M. (2022, 1 octubre). Trastornos De La Personalidad / Roca Bennasar, Miguel. LEXUS. Boland, R., Verduin, M. & Md, R. P. (2022). Kaplan & Sadock. Sinopsis de Psiquiatría (12th ed.). LWW. Carvalho, L. D. F. & Arruda, W. (2016, 1 mayo). Association Between Anxiety And Depression Symptoms With Pathological Personality Traits. psicología desde el caribe, 33(2), 3-20. https://doi.org/10.14482/psdc.33.2.7290 Caruso, R., Nanni, M. G., Riba, M., Sabato, S., Mitchell, A. J., Croce, E., & Grassi, L. (2017). Depressive Spectrum Disorders in Cancer: Prevalence, risk factors and screening for Depression: a Critical review. Acta Oncologica, 56(2), 146-155. https://doi.org/10.1080/0284186x.2016.1266090 Curran, L., Sharpe, L. & Butow, P. (2017). Anxiety in the context of cancer: A systematic review and development of an integrated model. Clinical Psychology Review, 56, 40-54. https://doi.org/10.1016/j.cpr.2017.06.003 DeYoung, C. G. (2015). Cybernetic Big Five Theory. Journal of Research in Personality, 56, 33-58. https://doi.org/10.1016/j.jrp.2014.07.004 Dong, J., Dai, Q., & Zhang, F. (2019). The Effect of marital status on endometrial cancer-related diagnosis and Prognosis: A Surveillance Epidemiology and End Results Database analysis. Future Oncology, 15(34), 3963-3976. https://doi.org/10.2217/fon-2019-0241 Ekselius, L. (2018). Personality disorder: a disease in disguise. Upsala Journal of Medical Sciences, 123(4), 194-204. https://doi.org/10.1080/03009734.2018.1526235 Fava, M., Farabaugh, A., Sickinger, A. H., Wright, E., Alpert, J. E., Sonawalla, S. B., Nierenberg, A. A., & Worthington, J. J. (2002). Personality disorders and depression. Psychological Medicine, 32(6), 1049-1057. https://doi.org/10.1017/s0033291702005780 Foster, J. A. & MacQueen, G. (2008, enero). Neurobiological Factors Linking Personality Traits and Major Depression. The Canadian Journal of Psychiatry, 53(1), 6-13. https://doi.org/10.1177/070674370805300103 Fjermestad-Noll, J., Ronningstam, E., Bach, B., Rosenbaum, B., & Simonsen, E. (2019). Characterological depression in patients with narcissistic personality disorder. Nordic Journal of Psychiatry, 73(8), 539-545. https://doi.org/10.1080/08039488.2019.1664630 Gawda, B., & Czubak, K. (2017). Prevalence of personality disorders in a general population among men and women. Psychological Reports, 120(3), 503-519. https://doi.org/10.1177/0033294117692807 Gescher, D. M., Kahl, K. G., Hillemacher, T., Frieling, H., Kuhn, J. & Frodl, T. (2018, 19 noviembre). Epigenetics in Personality Disorders: Today’s Insights. Frontiers in Psychiatry, 9. https://doi.org/10.3389/fpsyt.2018.00579 Giner Zaragoza, Francesc, Lera Calatayud, Guillem, Vidal Sánchez, María Luisa, Puchades Muñoz, Mari Paz, Rodenes Pérez, Ainhoa, Císcar Pons, Sonia, Chiclana Actis, Carlos, Martín Vivar, María, Garulo Ibáñez, Teresa, Tapia Alcañiz, José, Díaz Esteban, Elena, & Ferrer Ferrer, Lucía. (2015). Diagnóstico y prevalencia de trastornos de la personalidad en atención ambulatoria: estudio descriptivo. Revista de la Asociación Española de Neuropsiquiatría, 35(128), 789-799. https://dx.doi.org/10.4321/S0211-57352015000400007 Goerling, U., Hinz, A., Koch-Gromus, U. et al. Prevalence and severity of anxiety in cancer patients: results from a multi-center cohort study in Germany. J Cancer Res Clin Oncol 149, 6371–6379 (2023). https://doi.org/10.1007/s00432-023-04600-w Grassi, L., Caruso, R., Riba, M., Lloyd‐Williams, M., Kissane, D. W., Rodin, G., McFarland, D. C., Campos-Ródenas, R., Zachariae, R., Santini, D., & Ripamonti, C. (2023). Anxiety and Depression in adult cancer patients: ESMO Clinical Practice Guideline. ESMO Open, 8(2), 101155. https://doi.org/10.1016/j.esmoop.2023.101155 Habimana, S., Biracyaza, E., Mpunga, T., Nsabimana, E., Kayitesi, F., Nzamwita, P., & Jansen, S. (2023). Prevalence and associated factors of depression and anxiety among patients with cancer seeking treatment at the Butaro Cancer Center of Excellence in Rwanda. Frontiers in Public Health, 11. https://doi.org/10.3389/fpubh.2023.972360 Hashemi, S. M., Rafiemanesh, H., Aghamohammadi, T., Badakhsh, M., Amirshahi, M., Sari, M., Behnamfar, N., & Roudini, K. (2019). Prevalence of anxiety among breast cancer patients: A systematic review and meta-analysis. Breast Cancer, 27(2), 166-178. https://doi.org/10.1007/s12282-019-01031-9 Hayden, E. P., & Klein, D. N. (2001). Outcome of dysthymic disorder at 5-year follow-up: the effect of familial psychopathology, early adversity, personality, comorbidity, and chronic stress. The American journal of psychiatry, 158(11), 1864–1870. https://doi.org/10.1176/appi.ajp.158.11.1864 Hayward, R. D., Taylor, W. D., Smoski, M. J., Steffens, D. C. & Payne, M. E. (2013, enero). Association of Five-Factor Model Personality Domains and Facets with Presence, Onset, and Treatment Outcomes of Major Depression in Older Adults. The American Journal of Geriatric Psychiatry, 21(1), 88-96. https://doi.org/10.1016/j.jagp.2012.11.012 Hughes, D. J., Kratsiotis, I. K., Niven, K. & Holman, D. (2020). Personality traits and emotion regulation: A targeted review and recommendations. Emotion, 20(1), 63-67. https://doi.org/10.1037/emo0000644 İzci, F., Sarsanov, D., iyigun Erdogan, Z., Ilgun, A. S., Celebi, E., Alco, G., Kocaman, N., Ordu, C., Ozturk, A., Duymaz, T., Pilavci, K. N., Elbuken, F., Agacayak, F., Aktepe, F., Unveren, G., Ozdem, G., Eralp, Y. & Ozmen, V. (2018, 16 mayo). Impact of Personality Traits, Anxiety, Depression and Hopelessness -.ñLevels on Quality of Life in the Patients with Breast Cancer. European Journal of Breast Health. https://doi.org/10.5152/ejbh.2018.3724 Jeronimus, B. F., Kotov, R., Riese, H. & Ormel, J. (2016, 15 agosto). Neuroticism’s prospective association with mental disorders halves after adjustment for baseline symptoms and psychiatric history, but the adjusted association hardly decays with time: a meta-analysis on 59 longitudinal/prospective studies with 443 313 participants. Psychological Medicine, 46(14), 2883-2906. https://doi.org/10.1017/s0033291716001653 Jia, Y., Li, F., Liu, Y., Zhao, J., Leng, M. & Chen, L. (2017). Depression and cancer risk: a systematic review and meta-analysis. Public Health, 149, 138-148. https://doi.org/10.1016/j.puhe.2017.04.026 Kiecolt-Glaser, J. & Glaser, R. (1999). Psychoneuroimmunology and cancer: fact or fiction? European Journal of Cancer, 35(11), 1603-1607. https://doi.org/10.1016/s0959-8049(99)00197-5 Kotov, R., Gamez, W., Schmidt, F. & Watson, D. (2010). Linking “big” personality traits to anxiety, depressive, and substance use disorders: A meta-analysis. Psychological Bulletin, 136(5), 768-821. https://doi.org/10.1037/a0020327 Klein, D. N., Kotov, R. & Bufferd, S. J. (2011). Personality and Depression: Explanatory Models and Review of the Evidence. Annual Review of Clinical Psychology, 7(1), 269-295. https://doi.org/10.1146/annurev-clinpsy-032210-104540 Hughes, B., Costello, C., Pearman, J., Razavi, P., Bedford-Petersen, C., Ludwig, R. M., & Srivastava, S. (2021). The big five across socioeconomic status: measurement invariance, relationships, and age trends. Collabra, 7(1). https://doi.org/10.1525/collabra.24431 Li, J., Ma, H., Zhou, H., Huang, Y., Wu, L., Li, J. & Zhu, G. (2011, 3 marzo). Association Between DARPP-32 Gene Polymorphism and Personality Traits in Healthy Chinese-Han Subjects. Journal of Molecular Neuroscience, 44(1), 48-52. https://doi.org/10.1007/s12031-011-9505-7 Li, T. (2021, December). An Overview of Schizoid Personality Disorder. In 2021 4th International Conference on Humanities Education and Social Sciences (ICHESS 2021) (pp. 1657-1663). Atlantis Press. Llorente, Y. J., Tejada, B. A. M., & Herrera, J. L. (2019). Depresión en pacientes diagnosticados con cáncer en una institución de IV nivel en Montería, Colombia. Enfermería global, 18(4), 230-253. https://doi.org/10.6018/eglobal.18.4.354161 Ma, H., Huang, Y., Zhang, B., Jin, L., Cong, Z., Wang, Y., Li, J. & Zhu, G. (2013, 31 diciembre). Neurotensin Receptor 1 Gene Polymorphisms Are Associated with Personality Traits in Healthy Chinese Individuals. Neuropsychobiology, 69(1), 11-18. https://doi.org/10.1159/000356966 McFarland, D. C., Morita, J., & Alici, Y. (2019). Personality Disorders in Patients with Cancer. Oncology (Williston Park, N.Y.), 33(10), 686510. Mitchell, A. J., Ferguson, D. W., Gill, J., Paul, J., & Symonds, P. (2013). Depression and anxiety in long-term cancer survivors compared with spouses and healthy controls: A systematic review and meta-analysis. Lancet Oncology, 14(8), 721–732. http://dx.doi.org/10.1016/S1470-2045(13)70244-4 Mohammadi, M. R., Pourdehghan, P., Mostafavi, S., Khaleghi, A., & Ahmadi, N. (2023). Prevalence, sociodemographic correlates, and comorbidity of personality disorders in the general population of Iran. Current Psychology. https://doi.org/10.1007/s12144-023-04716-9 Molinera, G. (2009). Trastornos de personalidad y depresión. SEMERGEN, 35. Morris, T., Greer, S., Pettingale, K. W. & Watson, M. (1981). Patterns of expression of anger and their psychological correlates in women with breast cancer. Journal of Psychosomatic Research, 25(2), 111-117. https://doi.org/10.1016/0022-3999(81)90098-2 Nakaya, N., Bidstrup, P. E., Saito-Nakaya, K., Frederiksen, K., Koskenvuo, M., Pukkala, E., Kaprio, J., Floderus, B., Uchitomi, Y. & Johansen, C. (2010). Personality Traits and Cancer Risk and Survival Based on Finnish and Swedish Registry Data. American Journal of Epidemiology, 172(4), 377-385. https://doi.org/10.1093/aje/kwq046 Newton-Howes, G., Tyrer, P. & Johnson, T. (2006, enero). Personality disorder and the outcome of depression: Meta-analysis of published studies. British Journal of Psychiatry, 188(1), 13-20. https://doi.org/10.1192/bjp.188.1.13 Neyrinck, B. (2021). Histrionic personality features and depression: the role of emotion regulation and need frustration. https://studenttheses.uu.nl/handle/20.500.12932/41333 Noel, M. S., & Fiscella, K. (2019). Disparities in pancreatic cancer treatment and outcomes. Health equity, 3(1), 532-540. https://doi.org/10.1089/heq.2019.0057 Pezzin, L. E., Nattinger, A. B., McGinley, E. L., & Pezzin, L. E. (2017). Socioeconomic status and breast cancer treatment. Breast Cancer Research and Treatment, 167(1), 1-8. https://doi.org/10.1007/s10549-017-4490-3 Pitman, A., Suleman, S., Hyde, N. & Hodgkiss, A. (2018). Depression and anxiety in patients with cancer. BMJ, k1415. https://doi.org/10.1136/bmj.k1415 Portella, M. J., Harmer, C. J., Flint, J., Cowen, P. & Goodwin, G. M. (2005, abril). Enhanced Early Morning Salivary Cortisol in Neuroticism. American Journal of Psychiatry, 162(4), 807-809. https://doi.org/10.1176/appi.ajp.162.4.807 Prince, E. J., Siegel, D. J., Carroll, C. P., Sher, K. J. & Bienvenu, O. J. (2020, 15 noviembre). A longitudinal study of personality traits, anxiety, and depressive disorders in young adults. Anxiety, Stress, & Coping, 34(3), 299-307. https://doi.org/10.1080/10615806.2020.1845431 Puyané, M., Subirà, S., Torres, A., Roca, A., Garcia-Esteve, L. & Gelabert, E. (2022, febrero). Personality traits as a risk factor for postpartum depression: A systematic review and meta-analysis. Journal of Affective Disorders, 298, 577-589. https://doi.org/10.1016/j.jad.2021.11.010 Qiu, M., Yang, D., & Xu, R. (2016). Impact of marital status on survival of gastric adenocarcinoma patients: results from the Surveillance Epidemiology and End Results (SEER) database. Scientific Reports, 6(1). https://doi.org/10.1038/srep21098 Reif, A. (2015, 1 septiembre). Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing. Molecular Psychiatry, 21(6), 813-822. https://doi.org/10.1038/mp.2015.125 Rico, J. L., Restrepo, M., & Molina, M. (2005). Adaptación y validación de la escala hospitalaria de ansiedad y depresión (HAD) en una muestra de pacientes con cáncer del Instituto Nacional de Cancerología de Colombia. Avances en medición, 3(1), 73-86 Riedl D, Schüßler G. Factors associated with and risk factors for depression in cancer patients – A systematic literature review. Transl Oncol. (2022) 16:101328. doi: 10.1016/j.tranon.2021.101328 Rimlinger, B. (2010). Dépressions et troubles de la personnalité : influences réciproques. L’Encéphale, 36, S123-S126. https://doi.org/10.1016/s0013-7006(10)70043-9 Rivest J, Levenson J. Clinical features, assessment, and diagnosis of unipolar depressive disorders in patients with cancer (2019). In: Silver JM, Block SD. (eds.) UpToDate. Waltham, MA. Román Mella, F., Vinet, E. V., & Alarcón Muñoz, A. M. (2014). Escalas de Depresión, Ansiedad y Estrés (DASS-21): Adaptación y propiedades psicométricas en estudiantes secundarios de Temuco. Revista Argentina de Clínica Psicológica, XXIII(2),179-190.[fecha de Consulta 8 de Noviembre de 2022]. ISSN: 0327-6716. Recuperado de: https://www.redalyc.org/articulo.oa?id=281943265009 Rosenbluth, M., Macqueen, G., McIntyre, R. S., Beaulieu, S., Schaffer, A., & Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force (2012). The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid personality disorders. Annals of clinical psychiatry: official journal of the American Academy of Clinical Psychiatrists, 24(1), 56–68. Ruiz, F. J., Martín, M. B. G., Falcón, J. C. S., & González, P. O. (2017). The hierarchical factor structure of the Spanish version of Depression Anxiety and Stress Scale-21. International Journal of Psychology and Psychological Therapy, 17(1), 97-105. Sadeq, N. A. & Molinari, V. (2017, 26 diciembre). Personality and its Relationship to Depression and Cognition in Older Adults: Implications for Practice. Clinical Gerontologist, 41(5), 385-398. https://doi.org/10.1080/07317115.2017.1407981 Sanchez-Roige, S., Gray, J. C., MacKillop, J., Chen, C. H. & Palmer, A. A. (2017, 29 diciembre). The genetics of human personality. Genes, Brain and Behavior, 17(3), e12439. https://doi.org/10.1111/gbb.12439 Shah, A. Q., Prasad, D., Caropreso, L., Frey, B. N., & De Azevedo Cardoso, T. (2023). The Comorbidity between Borderline Personality Disorder (BPD) and Generalized Anxiety Disorder (GAD): a systematic review and meta-analysis. Journal of Psychiatric Research, 164, 304-314. https://doi.org/10.1016/j.jpsychires.2023.06.009 Shao, X. & Zhu, G. (2020, 13 mayo). Associations Among Monoamine Neurotransmitter Pathways, Personality Traits, and Major Depressive Disorder. Frontiers in Psychiatry, 11. https://doi.org/10.3389/fpsyt.2020.00381 Shea, M. T., Pilkonis, P. A., Beckham, E., Collins, J. F., Elkin, I., Sotsky, S. M. & Docherty, J. P. (1990). Personality disorders and treatment outcome in the NIMH treatment of depression collaborative research program. American Journal of Psychiatry 176, 711–718. Shi, F., Shaver, L.G., Kong, Y. et al. Sociodemographics and their impacts on risk factor awareness and beliefs about cancer and screening: results from a cross-sectional study in Newfoundland and Labrador. BMC Public Health 20, 1513 (2020). https://doi.org/10.1186/s12889-020-09616-2 Shou, Y., Lay, S. E., De Silva, H. S., Xyrakis, N., & Sellbom, M. (2021). Sociocultural Influences on Psychopathy Traits: A Cross-National Investigation. Journal of Personality Disorders, 35(2), 194-216. https://doi.org/10.1521/pedi_2019_33_428 Siegel, R. L., Miller, K. D., Wagle, N. S., & Jemal, A. (2023). Cancer Statistics, 2023. CA: A Cancer Journal for Clinicians, 73(1), 17-48. https://doi.org/10.3322/caac.21763 Smith, D. J., Escott-Price, V., Davies, G., Bailey, M. E. S., Colodro-Conde, L., Ward, J., Vedernikov, A., Marioni, R., Cullen, B., Lyall, D., Hagenaars, S. P., Liewald, D. C. M., Luciano, M., Gale, C. R., Ritchie, S. J., Hayward, C., Nicholl, B., Bulik-Sullivan, B., Adams, M., . . . O’Donovan, M. C. (2016, 12 abril). Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci. Molecular Psychiatry, 21(6), 749-757. https://doi.org/10.1038/mp.2016.49 Sontag, S. (2012). La enfermedad y sus metáforas \| El sida y sus metáforas. DEBOLS!LLO. Suárez, B. G., Molina, Á., Mosquera, J., Martinez, A., Lado, M., Forjan, M., Liste, R., Reboredo, C., Gómez‐Randulfe, I., Cordeiro, P., Coroas, O., & Deben, M. (2019). Socio-demographic characteristics and quality of life analysis of cancer survivors followed at a primary care center. Annals of Oncology, 30, v834. https://doi.org/10.1093/annonc/mdz275.019 Szelei, A., & Döme, P. (2020). Daganatos megbetegedések és a depresszió: rövid irodalmi áttekintés, Orvosi Hetilap, 161(22), 908-916. Retrieved Nov 4, 2022, from https://akjournals.com/view/journals/650/161/22/article-p908.xml Trevino, K. M., Saracino, R. M. & Roth, A. J. (2021). Symptomatology, assessment, and treatment of anxiety in older adults with cancer. Journal of Geriatric Oncology, 12(2), 316-319. https://doi.org/10.1016/j.jgo.2020.06.011 Torgersen, S., Kringlen, E., & Cramer, V. (2001). The prevalence of personality disorders in a community sample. Archives of General Psychiatry, 58(6), 590. https://doi.org/10.1001/archpsyc.58.6.590 Turhal, N. S., Demirhan, S., Satici, C., Cinar, C. & Kinar, A. (2013). Personality Traits in Cancer Patients. Asian Pacific Journal of Cancer Prevention, 14(8), 4515-4518. https://doi.org/10.7314/apjcp.2013.14.8.4515 Valderrama Rios, M. C. & Sánchez Pedraza, R. (2018). Trastornos de ansiedad y depresión en relación con la calidad de vida de pacientes con cáncer de mama en estadio localmente avanzado o diseminado. Revista Colombiana de Psiquiatría, 47(4), 211-220. https://doi.org/10.1016/j.rcp.2017.04.003 Vespa, A., Giulietti, M. V., Fabbietti, P., Di Rosa, M., Gattafoni, P., Sarzani, R., Arnaldi, G., Balercia, G., Berardi, R., Salvo, G., Attademo, L. & Spatuzzi, R. (2022, enero). Structural Analysis of Social Behavior: Using Cluster Analysis to Examine Intrapsychic Personality Traits Associated With Depression in Women With Breast Cancer. Cancer Control, 29, 107327482211033. https://doi.org/10.1177/10732748221103327 Vujicic, M. & Randjelovic, D. (2017). Personality traits as predictors of depression, anxiety, and stress with secondary school students of final years. Зборник радова Филозофског факултета у Приштини, 47-3, 217-237. https://doi.org/10.5937/zrffp47-14984 Wang, X., Wang, N., Zhong, L., Wang, S., Zheng, Y., Yang, B., Zhang, J., Lin, Y. & Wang, Z. (2020). Prognostic value of depression and anxiety on breast cancer recurrence and mortality: a systematic review and meta-analysis of 282,203 patients. Molecular Psychiatry, 25(12), 3186-3197. https://doi.org/10.1038/s41380-020-00865-6 Wang, H., Sun, X., Yue, H., Yang, Y. & Feng, D. (2021). The dyadic effects of personality traits on depression in advanced lung cancer patients and caregivers: The mediating role of acceptance of illness. European Journal of Cancer Care, 31(1). https://doi.org/10.1111/ecc.13538 Weber, H., Richter, J., Straube, B., Lueken, U., Domschke, K., Schartner, C., Klauke, B., Baumann, C., Pané-Farré, C., Jacob, C. P., Scholz, C. J., Zwanzger, P., Lang, T., Fehm, L., Jansen, A., Konrad, C., Fydrich, T., Wittmann, A., Pfleiderer, B., Reif, A. (2015). Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing. Molecular Psychiatry, 21(6), 813-822. https://doi.org/10.1038/mp.2015.125 White, M. C., Holman, D. M., Boehm, J., Peipins, L. A., Grossman, M., & Henley, S. J. (2014). Age and cancer risk. American Journal of Preventive Medicine, 46(3), S7-S15. https://doi.org/10.1016/j.amepre.2013.10.029 Winsper, C., Bilgin, A., Thompson, A., Marwaha, S., Chanen, A. M., Singh, S. P., Wang, A., & Furtado, V. (2019). The Prevalence of Personality Disorders in the Community: A Global Systematic review and Meta-analysis. The British Journal of Psychiatry, 216(2), 69-78. https://doi.org/10.1192/bjp.2019.166 Zhu, S., & Lei, C. (2023). Association between marital status and all-cause mortality of patients with metastatic breast cancer: a population-based study. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-36139-8 Salmon, C., Song, L., Muir, K., Pashayan, N., Dunning, A. M., Batra, J., Chambers, S. K., Stanford, J. L., Ostrander, E. A., Park, J. Y., Lin, H., Cussenot, O., Cancel‐Tassin, G., Ménégaux, F., Cordina‐Duverger, E., Kogevinas, M., Llorca, J., Kaneva, R., Slavov, C., . . . Parent, M. (2021). Marital status and prostate cancer incidence: A pooled analysis of 12 case–control studies from the PRACTICAL Consortium. European Journal of Epidemiology, 36(9), 913-925. https://doi.org/10.1007/s10654-021-00781-1
dc.rights.coar.fl_str_mv	http://purl.org/coar/access_right/c_abf2
dc.rights.license.spa.fl_str_mv	Reconocimiento 4.0 Internacional
dc.rights.uri.spa.fl_str_mv	http://creativecommons.org/licenses/by/4.0/
dc.rights.accessrights.spa.fl_str_mv	info:eu-repo/semantics/openAccess
rights_invalid_str_mv	Reconocimiento 4.0 Internacional http://creativecommons.org/licenses/by/4.0/ http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv	openAccess
dc.format.extent.spa.fl_str_mv	[73] páginas
dc.format.mimetype.spa.fl_str_mv	application/pdf
dc.publisher.spa.fl_str_mv	Universidad Nacional de Colombia
dc.publisher.program.spa.fl_str_mv	Bogotá - Medicina - Especialidad en Psiquiatría
dc.publisher.faculty.spa.fl_str_mv	Facultad de Medicina
dc.publisher.place.spa.fl_str_mv	Bogotá, Colombia
dc.publisher.branch.spa.fl_str_mv	Universidad Nacional de Colombia - Sede Bogotá
institution	Universidad Nacional de Colombia
bitstream.url.fl_str_mv	https://repositorio.unal.edu.co/bitstream/unal/85563/1/license.txt https://repositorio.unal.edu.co/bitstream/unal/85563/2/1026286522.2024.pdf https://repositorio.unal.edu.co/bitstream/unal/85563/3/1026286522.2024.pdf.jpg
bitstream.checksum.fl_str_mv	eb34b1cf90b7e1103fc9dfd26be24b4a 9b377ede8bed883d39e8bc52a3c60987 91b35c752ff9ec029d1677ee77358485
bitstream.checksumAlgorithm.fl_str_mv	MD5 MD5 MD5
repository.name.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
repository.mail.fl_str_mv	repositorio_nal@unal.edu.co
_version_	1806886424984682496
spelling	Reconocimiento 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Urrego Mendoza, Diana Zulima51d6219bd2d1f9df032cd13d344000f8Sánchez Pedraza, Ricardo71d39599cff2e2eb6af28ec7d259fc60Herrera Leiva, Lucas Mateo6097efce12378c2f46618b8ac1d2739b2024-01-31T17:03:32Z2024-01-31T17:03:32Z2024https://repositorio.unal.edu.co/handle/unal/85563Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/Resumen Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer El funcionamiento de la personalidad determina aspectos emocionales, cognitivos y comportamentales en los individuos. A partir de esta noción, hallar la compleja interrelación entre algunos rasgos de personalidad y los síntomas de depresión y ansiedad ha representado una fuente de interés significativo en la psiquiatría, de acuerdo con la comorbilidad y las consecuencias de estos fenómenos en términos de diagnóstico, tratamiento y pronóstico. A tal punto que se ha planteado, a raíz de ciertas presentaciones clínicas, un continuum entre algunos grupos de personalidad y síntomas afectivos, sin definir este hecho de manera concluyente. Con base en esto, se han realizado múltiples estudios que buscan asociación entre los rasgos de personalidad y los síntomas de ansiedad y depresión, que diluciden la importancia de este vínculo y que contribuyan al desarrollo de la práctica clínica. Objetivo: determinar la asociación entre los rasgos de personalidad y los síntomas de ansiedad y depresión en pacientes con cáncer del Instituto Nacional de Cancerología durante los años 2021 y 2022. Metodología: estudio observacional analítico, de corte transversal, el cual incluyó 399 pacientes del Instituto Nacional de Cancerología que se encuentren en fase de tratamiento de alguna enfermedad neoplásica, abordadas en los servicios que atienden los tipos de cáncer más frecuentes, mayores de 18 años que aceptaron hacer parte del estudio; a quienes se les aplicaron dos tipos de cuestionarios (Test de Salamanca y DASS-21), en busca de hallar la posible correlación entre los rasgos de personalidad y los síntomas de ansiedad y depresión. Resultados: estos pacientes tuvieron una edad promedio de 58 años (DE=13.9), en la mayoría de los casos fueron mujeres (69.4%; N=277). La configuración de personalidad más prevalente en este estudio fue la anancástica con 229 pacientes con estos rasgos (57.39%; IC95%: 54.39% a 60.39%), seguida de la histriónica, en la que se identificaron 157 pacientes con estos rasgos (39.35% (IC 95: 36.35% a 42.35%)) y, de manera relevante, los rasgos de personalidad esquizoide reconocidos en 149 pacientes (37.34%; (IC: 95: 34.34% a 40.33%)). En cuanto a los síntomas de depresión, en primer lugar se encontró la presentación moderada (10.03%, N=40), seguida de la leve (9.77%, N=39), la muy grave (6.52%, N=26) y finalmente la presentación grave (5.26%, N=21); y sobre los síntomas de ansiedad primero se tuvo en cuenta la presentación moderada (15.54%, N=62), seguida de la presentación muy grave (10.28%, N=41), luego la leve (9.02%, N=36) y al final la grave (4.51%, N=18). El análisis multivariado agrupó tres factores, el principal determina la asociación entre rasgos de personalidad y síntomas de depresión y ansiedad, con un hallazgo en particular de ausencia de rasgos de personalidad en correlación con la ausencia de síntomas de ansiedad y depresión. Palabras clave: rasgos de personalidad, síntomas de ansiedad, síntomas de depresión, paciente con cáncer. (Texto tomado de la fuente)Personality traits and their association with symptoms of anxiety and depression in cancer patients. The functioning of personality determines emotional, cognitive and behavioral aspects in individuals. From this notion, finding the complex interrelationship between some personality traits and symptoms of depression and anxiety has represented a source of significant interest in psychiatry, according to the comorbidity and consequences of these phenomena in terms of diagnosis, treatment and prognosis. To such an extent that a continuum between some personality groups and affective symptoms has been proposed, following certain clinical presentations, without defining this fact conclusively. Based on this, multiple studies have been carried out looking for associations between personality traits and symptoms of anxiety and depression, to elucidate the importance of this link and to contribute to the development of clinical practice. Objective: to determine the association between personality traits and symptoms of anxiety and depression in cancer patients at the National Cancer Institute during the years 2021 and 2022. Methodology: analytical observational study, cross-sectional, which included 399 patients of the National Cancer Institute who are in the treatment phase of a neoplastic disease, addressed in the services that treat the most common types of cancer, over 18 years of age who agreed to be part of the study; to whom two types of questionnaires were applied (Salamanca Test and DASS-21), in order to find the possible correlation between personality traits and symptoms of anxiety and depression. Results: these patients had a mean age of 58 years (SD=13.9), most of them were women (69.4%; N=277). The most prevalent personality configuration in this study was anancastic with 229 patients with these traits (57.39%; CI95%: 54.39% to 60.39%), followed by histrionic, in which 157 patients were identified with these traits (39.35% (CI 95: 36.35% to 42.35%)) and, relevantly, schizoid personality traits recognized in 149 patients (37.34%; (CI: 95: 34.34% to 40.33%)). Regarding depressive symptoms, moderate presentation was found first (10.03%, N=40), followed by mild (9.77%, N=39), very severe (6.52%, N=26) and finally severe presentation (5. 26%, N=21); and on anxiety symptoms first the moderate presentation was considered (15.54%, N=62), followed by the very severe presentation (10.28%, N=41), then the mild (9.02%, N=36) and finally the severe (4.51%, N=18). The multivariate analysis grouped three factors, the main one determining the association between personality traits and symptoms of depression and anxiety, with a particular finding of absence of personality traits correlating with absence of symptoms of anxiety and depression. Keywords: personality traits, anxiety symptoms, depression symptoms, cancer patient.Especialidades MédicasEspecialista en Psiquiatría[73] páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina - Especialidad en PsiquiatríaFacultad de MedicinaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá610 - Medicina y salud::616 - Enfermedades610 - Medicina y salud::613 - Salud y seguridad personalTrastornos de la personalidadTrastornos de ansiedadTrastorno depresivoPersonality disordersAnxiety disordersDepressive disorderEnfermos con cáncer - Salud mentalCancer - Patients - Mental healthRasgos de personalidadSíntomas de ansiedadSíntomas de depresiónPaciente con cáncerPersonality traitsAnxiety symptomsDepression symptomsCancer patientRasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncerPersonality traits and their association with symptoms of anxiety and depression in cancer patients.Trabajo de grado - Especialidad Médicainfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/acceptedVersionhttp://purl.org/coar/resource_type/c_7a1fTexthttp://purl.org/redcol/resource_type/TPAdams, M. J., Howard, D. M., Luciano, M., Clarke, T. K., Davies, G., Hill, W. D., Smith, D., Deary, I. J., Porteous, D. J. & McIntosh, A. M. (2019, 2 octubre). Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition. Psychological Medicine, 50(15), 2526-2535. https://doi.org/10.1017/s0033291719002629Akiskal, H. S. (1983, 1 julio). The Relationship of Personality to Affective Disorders. Archives of General Psychiatry, 40(7), 801. https://doi.org/10.1001/archpsyc.1983.01790060099013Alagizy, H. A., Soltan, M. E., Soliman, S., Hegazy, N. N., & Gohar, S. (2020). Anxiety, depression and perceived stress among breast cancer patients: Single Institute experience. Middle East Current Psychiatry, 27(1). https://doi.org/10.1186/s43045-020-00036-xAméndola, L., Weary, D. & Zobel, G. (2022, octubre). Effects of personality on assessments of anxiety and cognition. Neuroscience & Biobehavioral Reviews, 141, 104827. https://doi.org/10.1016/j.neubiorev.2022.104827Antoni, M. H., Lutgendorf, S. K., Cole, S. W., Dhabhar, F. S., Sephton, S. E., McDonald, P. G., Stefanek, M. & Sood, A. K. (2006). The influence of bio-behavioural factors on tumour biology: pathways and mechanisms. Nature Reviews Cancer, 6(3), 240-248. https://doi.org/10.1038/nrc1820Bagby, R. M., Ryder, A. G. & Cristi, C. (2002, julio). Psychosocial and clinical predictorsof response to pharmacotherapy for depression. Journal of Psychiatry and Neuroscience, 4(27), 250-257.Barlow, D. H., Ellard, K. K., Sauer-Zavala, S., Bullis, J. R. & Carl, J. R. (2014, septiembre). The Origins of Neuroticism. Perspectives on Psychological Science, 9(5), 481-496. https://doi.org/10.1177/1745691614544528Bennasar, R. M. (2022, 1 octubre). Trastornos De La Personalidad / Roca Bennasar, Miguel. LEXUS.Boland, R., Verduin, M. & Md, R. P. (2022). Kaplan & Sadock. Sinopsis de Psiquiatría (12th ed.). LWW.Carvalho, L. D. F. & Arruda, W. (2016, 1 mayo). Association Between Anxiety And Depression Symptoms With Pathological Personality Traits. psicología desde el caribe, 33(2), 3-20. https://doi.org/10.14482/psdc.33.2.7290Caruso, R., Nanni, M. G., Riba, M., Sabato, S., Mitchell, A. J., Croce, E., & Grassi, L. (2017). Depressive Spectrum Disorders in Cancer: Prevalence, risk factors and screening for Depression: a Critical review. Acta Oncologica, 56(2), 146-155. https://doi.org/10.1080/0284186x.2016.1266090Curran, L., Sharpe, L. & Butow, P. (2017). Anxiety in the context of cancer: A systematic review and development of an integrated model. Clinical Psychology Review, 56, 40-54. https://doi.org/10.1016/j.cpr.2017.06.003DeYoung, C. G. (2015). Cybernetic Big Five Theory. Journal of Research in Personality, 56, 33-58. https://doi.org/10.1016/j.jrp.2014.07.004Dong, J., Dai, Q., & Zhang, F. (2019). The Effect of marital status on endometrial cancer-related diagnosis and Prognosis: A Surveillance Epidemiology and End Results Database analysis. Future Oncology, 15(34), 3963-3976. https://doi.org/10.2217/fon-2019-0241Ekselius, L. (2018). Personality disorder: a disease in disguise. Upsala Journal of Medical Sciences, 123(4), 194-204. https://doi.org/10.1080/03009734.2018.1526235Fava, M., Farabaugh, A., Sickinger, A. H., Wright, E., Alpert, J. E., Sonawalla, S. B., Nierenberg, A. A., & Worthington, J. J. (2002). Personality disorders and depression. Psychological Medicine, 32(6), 1049-1057. https://doi.org/10.1017/s0033291702005780Foster, J. A. & MacQueen, G. (2008, enero). Neurobiological Factors Linking Personality Traits and Major Depression. The Canadian Journal of Psychiatry, 53(1), 6-13. https://doi.org/10.1177/070674370805300103Fjermestad-Noll, J., Ronningstam, E., Bach, B., Rosenbaum, B., & Simonsen, E. (2019). Characterological depression in patients with narcissistic personality disorder. Nordic Journal of Psychiatry, 73(8), 539-545. https://doi.org/10.1080/08039488.2019.1664630Gawda, B., & Czubak, K. (2017). Prevalence of personality disorders in a general population among men and women. Psychological Reports, 120(3), 503-519. https://doi.org/10.1177/0033294117692807Gescher, D. M., Kahl, K. G., Hillemacher, T., Frieling, H., Kuhn, J. & Frodl, T. (2018, 19 noviembre). Epigenetics in Personality Disorders: Today’s Insights. Frontiers in Psychiatry, 9. https://doi.org/10.3389/fpsyt.2018.00579Giner Zaragoza, Francesc, Lera Calatayud, Guillem, Vidal Sánchez, María Luisa, Puchades Muñoz, Mari Paz, Rodenes Pérez, Ainhoa, Císcar Pons, Sonia, Chiclana Actis, Carlos, Martín Vivar, María, Garulo Ibáñez, Teresa, Tapia Alcañiz, José, Díaz Esteban, Elena, & Ferrer Ferrer, Lucía. (2015). Diagnóstico y prevalencia de trastornos de la personalidad en atención ambulatoria: estudio descriptivo. Revista de la Asociación Española de Neuropsiquiatría, 35(128), 789-799. https://dx.doi.org/10.4321/S0211-57352015000400007Goerling, U., Hinz, A., Koch-Gromus, U. et al. Prevalence and severity of anxiety in cancer patients: results from a multi-center cohort study in Germany. J Cancer Res Clin Oncol 149, 6371–6379 (2023). https://doi.org/10.1007/s00432-023-04600-wGrassi, L., Caruso, R., Riba, M., Lloyd‐Williams, M., Kissane, D. W., Rodin, G., McFarland, D. C., Campos-Ródenas, R., Zachariae, R., Santini, D., & Ripamonti, C. (2023). Anxiety and Depression in adult cancer patients: ESMO Clinical Practice Guideline. ESMO Open, 8(2), 101155. https://doi.org/10.1016/j.esmoop.2023.101155Habimana, S., Biracyaza, E., Mpunga, T., Nsabimana, E., Kayitesi, F., Nzamwita, P., & Jansen, S. (2023). Prevalence and associated factors of depression and anxiety among patients with cancer seeking treatment at the Butaro Cancer Center of Excellence in Rwanda. Frontiers in Public Health, 11. https://doi.org/10.3389/fpubh.2023.972360Hashemi, S. M., Rafiemanesh, H., Aghamohammadi, T., Badakhsh, M., Amirshahi, M., Sari, M., Behnamfar, N., & Roudini, K. (2019). Prevalence of anxiety among breast cancer patients: A systematic review and meta-analysis. Breast Cancer, 27(2), 166-178. https://doi.org/10.1007/s12282-019-01031-9Hayden, E. P., & Klein, D. N. (2001). Outcome of dysthymic disorder at 5-year follow-up: the effect of familial psychopathology, early adversity, personality, comorbidity, and chronic stress. The American journal of psychiatry, 158(11), 1864–1870. https://doi.org/10.1176/appi.ajp.158.11.1864Hayward, R. D., Taylor, W. D., Smoski, M. J., Steffens, D. C. & Payne, M. E. (2013, enero). Association of Five-Factor Model Personality Domains and Facets with Presence, Onset, and Treatment Outcomes of Major Depression in Older Adults. The American Journal of Geriatric Psychiatry, 21(1), 88-96. https://doi.org/10.1016/j.jagp.2012.11.012Hughes, D. J., Kratsiotis, I. K., Niven, K. & Holman, D. (2020). Personality traits and emotion regulation: A targeted review and recommendations. Emotion, 20(1), 63-67. https://doi.org/10.1037/emo0000644İzci, F., Sarsanov, D., iyigun Erdogan, Z., Ilgun, A. S., Celebi, E., Alco, G., Kocaman, N., Ordu, C., Ozturk, A., Duymaz, T., Pilavci, K. N., Elbuken, F., Agacayak, F., Aktepe, F., Unveren, G., Ozdem, G., Eralp, Y. & Ozmen, V. (2018, 16 mayo). Impact of Personality Traits, Anxiety, Depression and Hopelessness -.ñLevels on Quality of Life in the Patients with Breast Cancer. European Journal of Breast Health. https://doi.org/10.5152/ejbh.2018.3724Jeronimus, B. F., Kotov, R., Riese, H. & Ormel, J. (2016, 15 agosto). Neuroticism’s prospective association with mental disorders halves after adjustment for baseline symptoms and psychiatric history, but the adjusted association hardly decays with time: a meta-analysis on 59 longitudinal/prospective studies with 443 313 participants. Psychological Medicine, 46(14), 2883-2906. https://doi.org/10.1017/s0033291716001653Jia, Y., Li, F., Liu, Y., Zhao, J., Leng, M. & Chen, L. (2017). Depression and cancer risk: a systematic review and meta-analysis. Public Health, 149, 138-148. https://doi.org/10.1016/j.puhe.2017.04.026Kiecolt-Glaser, J. & Glaser, R. (1999). Psychoneuroimmunology and cancer: fact or fiction? European Journal of Cancer, 35(11), 1603-1607. https://doi.org/10.1016/s0959-8049(99)00197-5Kotov, R., Gamez, W., Schmidt, F. & Watson, D. (2010). Linking “big” personality traits to anxiety, depressive, and substance use disorders: A meta-analysis. Psychological Bulletin, 136(5), 768-821. https://doi.org/10.1037/a0020327Klein, D. N., Kotov, R. & Bufferd, S. J. (2011). Personality and Depression: Explanatory Models and Review of the Evidence. Annual Review of Clinical Psychology, 7(1), 269-295. https://doi.org/10.1146/annurev-clinpsy-032210-104540Hughes, B., Costello, C., Pearman, J., Razavi, P., Bedford-Petersen, C., Ludwig, R. M., & Srivastava, S. (2021). The big five across socioeconomic status: measurement invariance, relationships, and age trends. Collabra, 7(1). https://doi.org/10.1525/collabra.24431Li, J., Ma, H., Zhou, H., Huang, Y., Wu, L., Li, J. & Zhu, G. (2011, 3 marzo). Association Between DARPP-32 Gene Polymorphism and Personality Traits in Healthy Chinese-Han Subjects. Journal of Molecular Neuroscience, 44(1), 48-52. https://doi.org/10.1007/s12031-011-9505-7Li, T. (2021, December). An Overview of Schizoid Personality Disorder. In 2021 4th International Conference on Humanities Education and Social Sciences (ICHESS 2021) (pp. 1657-1663). Atlantis Press.Llorente, Y. J., Tejada, B. A. M., & Herrera, J. L. (2019). Depresión en pacientes diagnosticados con cáncer en una institución de IV nivel en Montería, Colombia. Enfermería global, 18(4), 230-253. https://doi.org/10.6018/eglobal.18.4.354161Ma, H., Huang, Y., Zhang, B., Jin, L., Cong, Z., Wang, Y., Li, J. & Zhu, G. (2013, 31 diciembre). Neurotensin Receptor 1 Gene Polymorphisms Are Associated with Personality Traits in Healthy Chinese Individuals. Neuropsychobiology, 69(1), 11-18. https://doi.org/10.1159/000356966McFarland, D. C., Morita, J., & Alici, Y. (2019). Personality Disorders in Patients with Cancer. Oncology (Williston Park, N.Y.), 33(10), 686510.Mitchell, A. J., Ferguson, D. W., Gill, J., Paul, J., & Symonds, P. (2013). Depression and anxiety in long-term cancer survivors compared with spouses and healthy controls: A systematic review and meta-analysis. Lancet Oncology, 14(8), 721–732. http://dx.doi.org/10.1016/S1470-2045(13)70244-4Mohammadi, M. R., Pourdehghan, P., Mostafavi, S., Khaleghi, A., & Ahmadi, N. (2023). Prevalence, sociodemographic correlates, and comorbidity of personality disorders in the general population of Iran. Current Psychology. https://doi.org/10.1007/s12144-023-04716-9Molinera, G. (2009). Trastornos de personalidad y depresión. SEMERGEN, 35.Morris, T., Greer, S., Pettingale, K. W. & Watson, M. (1981). Patterns of expression of anger and their psychological correlates in women with breast cancer. Journal of Psychosomatic Research, 25(2), 111-117. https://doi.org/10.1016/0022-3999(81)90098-2Nakaya, N., Bidstrup, P. E., Saito-Nakaya, K., Frederiksen, K., Koskenvuo, M., Pukkala, E., Kaprio, J., Floderus, B., Uchitomi, Y. & Johansen, C. (2010). Personality Traits and Cancer Risk and Survival Based on Finnish and Swedish Registry Data. American Journal of Epidemiology, 172(4), 377-385. https://doi.org/10.1093/aje/kwq046Newton-Howes, G., Tyrer, P. & Johnson, T. (2006, enero). Personality disorder and the outcome of depression: Meta-analysis of published studies. British Journal of Psychiatry, 188(1), 13-20. https://doi.org/10.1192/bjp.188.1.13Neyrinck, B. (2021). Histrionic personality features and depression: the role of emotion regulation and need frustration. https://studenttheses.uu.nl/handle/20.500.12932/41333Noel, M. S., & Fiscella, K. (2019). Disparities in pancreatic cancer treatment and outcomes. Health equity, 3(1), 532-540. https://doi.org/10.1089/heq.2019.0057Pezzin, L. E., Nattinger, A. B., McGinley, E. L., & Pezzin, L. E. (2017). Socioeconomic status and breast cancer treatment. Breast Cancer Research and Treatment, 167(1), 1-8. https://doi.org/10.1007/s10549-017-4490-3Pitman, A., Suleman, S., Hyde, N. & Hodgkiss, A. (2018). Depression and anxiety in patients with cancer. BMJ, k1415. https://doi.org/10.1136/bmj.k1415Portella, M. J., Harmer, C. J., Flint, J., Cowen, P. & Goodwin, G. M. (2005, abril). Enhanced Early Morning Salivary Cortisol in Neuroticism. American Journal of Psychiatry, 162(4), 807-809. https://doi.org/10.1176/appi.ajp.162.4.807Prince, E. J., Siegel, D. J., Carroll, C. P., Sher, K. J. & Bienvenu, O. J. (2020, 15 noviembre). A longitudinal study of personality traits, anxiety, and depressive disorders in young adults. Anxiety, Stress, & Coping, 34(3), 299-307. https://doi.org/10.1080/10615806.2020.1845431Puyané, M., Subirà, S., Torres, A., Roca, A., Garcia-Esteve, L. & Gelabert, E. (2022, febrero). Personality traits as a risk factor for postpartum depression: A systematic review and meta-analysis. Journal of Affective Disorders, 298, 577-589. https://doi.org/10.1016/j.jad.2021.11.010Qiu, M., Yang, D., & Xu, R. (2016). Impact of marital status on survival of gastric adenocarcinoma patients: results from the Surveillance Epidemiology and End Results (SEER) database. Scientific Reports, 6(1). https://doi.org/10.1038/srep21098Reif, A. (2015, 1 septiembre). Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing. Molecular Psychiatry, 21(6), 813-822. https://doi.org/10.1038/mp.2015.125Rico, J. L., Restrepo, M., & Molina, M. (2005). Adaptación y validación de la escala hospitalaria de ansiedad y depresión (HAD) en una muestra de pacientes con cáncer del Instituto Nacional de Cancerología de Colombia. Avances en medición, 3(1), 73-86Riedl D, Schüßler G. Factors associated with and risk factors for depression in cancer patients – A systematic literature review. Transl Oncol. (2022) 16:101328. doi: 10.1016/j.tranon.2021.101328Rimlinger, B. (2010). Dépressions et troubles de la personnalité : influences réciproques. L’Encéphale, 36, S123-S126. https://doi.org/10.1016/s0013-7006(10)70043-9Rivest J, Levenson J. Clinical features, assessment, and diagnosis of unipolar depressive disorders in patients with cancer (2019). In: Silver JM, Block SD. (eds.) UpToDate. Waltham, MA.Román Mella, F., Vinet, E. V., & Alarcón Muñoz, A. M. (2014). Escalas de Depresión, Ansiedad y Estrés (DASS-21): Adaptación y propiedades psicométricas en estudiantes secundarios de Temuco. Revista Argentina de Clínica Psicológica, XXIII(2),179-190.[fecha de Consulta 8 de Noviembre de 2022]. ISSN: 0327-6716. Recuperado de: https://www.redalyc.org/articulo.oa?id=281943265009Rosenbluth, M., Macqueen, G., McIntyre, R. S., Beaulieu, S., Schaffer, A., & Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force (2012). The Canadian Network for Mood and Anxiety Treatments (CANMAT) task force recommendations for the management of patients with mood disorders and comorbid personality disorders. Annals of clinical psychiatry: official journal of the American Academy of Clinical Psychiatrists, 24(1), 56–68.Ruiz, F. J., Martín, M. B. G., Falcón, J. C. S., & González, P. O. (2017). The hierarchical factor structure of the Spanish version of Depression Anxiety and Stress Scale-21. International Journal of Psychology and Psychological Therapy, 17(1), 97-105.Sadeq, N. A. & Molinari, V. (2017, 26 diciembre). Personality and its Relationship to Depression and Cognition in Older Adults: Implications for Practice. Clinical Gerontologist, 41(5), 385-398. https://doi.org/10.1080/07317115.2017.1407981Sanchez-Roige, S., Gray, J. C., MacKillop, J., Chen, C. H. & Palmer, A. A. (2017, 29 diciembre). The genetics of human personality. Genes, Brain and Behavior, 17(3), e12439. https://doi.org/10.1111/gbb.12439Shah, A. Q., Prasad, D., Caropreso, L., Frey, B. N., & De Azevedo Cardoso, T. (2023). The Comorbidity between Borderline Personality Disorder (BPD) and Generalized Anxiety Disorder (GAD): a systematic review and meta-analysis. Journal of Psychiatric Research, 164, 304-314. https://doi.org/10.1016/j.jpsychires.2023.06.009Shao, X. & Zhu, G. (2020, 13 mayo). Associations Among Monoamine Neurotransmitter Pathways, Personality Traits, and Major Depressive Disorder. Frontiers in Psychiatry, 11. https://doi.org/10.3389/fpsyt.2020.00381Shea, M. T., Pilkonis, P. A., Beckham, E., Collins, J. F., Elkin, I., Sotsky, S. M. & Docherty, J. P. (1990). Personality disorders and treatment outcome in the NIMH treatment of depression collaborative research program. American Journal of Psychiatry 176, 711–718.Shi, F., Shaver, L.G., Kong, Y. et al. Sociodemographics and their impacts on risk factor awareness and beliefs about cancer and screening: results from a cross-sectional study in Newfoundland and Labrador. BMC Public Health 20, 1513 (2020). https://doi.org/10.1186/s12889-020-09616-2Shou, Y., Lay, S. E., De Silva, H. S., Xyrakis, N., & Sellbom, M. (2021). Sociocultural Influences on Psychopathy Traits: A Cross-National Investigation. Journal of Personality Disorders, 35(2), 194-216. https://doi.org/10.1521/pedi_2019_33_428Siegel, R. L., Miller, K. D., Wagle, N. S., & Jemal, A. (2023). Cancer Statistics, 2023. CA: A Cancer Journal for Clinicians, 73(1), 17-48. https://doi.org/10.3322/caac.21763Smith, D. J., Escott-Price, V., Davies, G., Bailey, M. E. S., Colodro-Conde, L., Ward, J., Vedernikov, A., Marioni, R., Cullen, B., Lyall, D., Hagenaars, S. P., Liewald, D. C. M., Luciano, M., Gale, C. R., Ritchie, S. J., Hayward, C., Nicholl, B., Bulik-Sullivan, B., Adams, M., . . . O’Donovan, M. C. (2016, 12 abril). Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci. Molecular Psychiatry, 21(6), 749-757. https://doi.org/10.1038/mp.2016.49Sontag, S. (2012). La enfermedad y sus metáforas \| El sida y sus metáforas. DEBOLS!LLO.Suárez, B. G., Molina, Á., Mosquera, J., Martinez, A., Lado, M., Forjan, M., Liste, R., Reboredo, C., Gómez‐Randulfe, I., Cordeiro, P., Coroas, O., & Deben, M. (2019). Socio-demographic characteristics and quality of life analysis of cancer survivors followed at a primary care center. Annals of Oncology, 30, v834. https://doi.org/10.1093/annonc/mdz275.019Szelei, A., & Döme, P. (2020). Daganatos megbetegedések és a depresszió: rövid irodalmi áttekintés, Orvosi Hetilap, 161(22), 908-916. Retrieved Nov 4, 2022, from https://akjournals.com/view/journals/650/161/22/article-p908.xmlTrevino, K. M., Saracino, R. M. & Roth, A. J. (2021). Symptomatology, assessment, and treatment of anxiety in older adults with cancer. Journal of Geriatric Oncology, 12(2), 316-319. https://doi.org/10.1016/j.jgo.2020.06.011Torgersen, S., Kringlen, E., & Cramer, V. (2001). The prevalence of personality disorders in a community sample. Archives of General Psychiatry, 58(6), 590. https://doi.org/10.1001/archpsyc.58.6.590Turhal, N. S., Demirhan, S., Satici, C., Cinar, C. & Kinar, A. (2013). Personality Traits in Cancer Patients. Asian Pacific Journal of Cancer Prevention, 14(8), 4515-4518. https://doi.org/10.7314/apjcp.2013.14.8.4515Valderrama Rios, M. C. & Sánchez Pedraza, R. (2018). Trastornos de ansiedad y depresión en relación con la calidad de vida de pacientes con cáncer de mama en estadio localmente avanzado o diseminado. Revista Colombiana de Psiquiatría, 47(4), 211-220. https://doi.org/10.1016/j.rcp.2017.04.003Vespa, A., Giulietti, M. V., Fabbietti, P., Di Rosa, M., Gattafoni, P., Sarzani, R., Arnaldi, G., Balercia, G., Berardi, R., Salvo, G., Attademo, L. & Spatuzzi, R. (2022, enero). Structural Analysis of Social Behavior: Using Cluster Analysis to Examine Intrapsychic Personality Traits Associated With Depression in Women With Breast Cancer. Cancer Control, 29, 107327482211033. https://doi.org/10.1177/10732748221103327Vujicic, M. & Randjelovic, D. (2017). Personality traits as predictors of depression, anxiety, and stress with secondary school students of final years. Зборник радова Филозофског факултета у Приштини, 47-3, 217-237. https://doi.org/10.5937/zrffp47-14984Wang, X., Wang, N., Zhong, L., Wang, S., Zheng, Y., Yang, B., Zhang, J., Lin, Y. & Wang, Z. (2020). Prognostic value of depression and anxiety on breast cancer recurrence and mortality: a systematic review and meta-analysis of 282,203 patients. Molecular Psychiatry, 25(12), 3186-3197. https://doi.org/10.1038/s41380-020-00865-6Wang, H., Sun, X., Yue, H., Yang, Y. & Feng, D. (2021). The dyadic effects of personality traits on depression in advanced lung cancer patients and caregivers: The mediating role of acceptance of illness. European Journal of Cancer Care, 31(1). https://doi.org/10.1111/ecc.13538Weber, H., Richter, J., Straube, B., Lueken, U., Domschke, K., Schartner, C., Klauke, B., Baumann, C., Pané-Farré, C., Jacob, C. P., Scholz, C. J., Zwanzger, P., Lang, T., Fehm, L., Jansen, A., Konrad, C., Fydrich, T., Wittmann, A., Pfleiderer, B., Reif, A. (2015). Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing. Molecular Psychiatry, 21(6), 813-822. https://doi.org/10.1038/mp.2015.125White, M. C., Holman, D. M., Boehm, J., Peipins, L. A., Grossman, M., & Henley, S. J. (2014). Age and cancer risk. American Journal of Preventive Medicine, 46(3), S7-S15. https://doi.org/10.1016/j.amepre.2013.10.029Winsper, C., Bilgin, A., Thompson, A., Marwaha, S., Chanen, A. M., Singh, S. P., Wang, A., & Furtado, V. (2019). The Prevalence of Personality Disorders in the Community: A Global Systematic review and Meta-analysis. The British Journal of Psychiatry, 216(2), 69-78. https://doi.org/10.1192/bjp.2019.166Zhu, S., & Lei, C. (2023). Association between marital status and all-cause mortality of patients with metastatic breast cancer: a population-based study. Scientific Reports, 13(1). https://doi.org/10.1038/s41598-023-36139-8Salmon, C., Song, L., Muir, K., Pashayan, N., Dunning, A. M., Batra, J., Chambers, S. K., Stanford, J. L., Ostrander, E. A., Park, J. Y., Lin, H., Cussenot, O., Cancel‐Tassin, G., Ménégaux, F., Cordina‐Duverger, E., Kogevinas, M., Llorca, J., Kaneva, R., Slavov, C., . . . Parent, M. (2021). Marital status and prostate cancer incidence: A pooled analysis of 12 case–control studies from the PRACTICAL Consortium. European Journal of Epidemiology, 36(9), 913-925. https://doi.org/10.1007/s10654-021-00781-1EstudiantesInvestigadoresMaestrosPadres y familiasLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/85563/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINAL1026286522.2024.pdf1026286522.2024.pdfTesis de Especialidad en Psiquiatríaapplication/pdf1010720https://repositorio.unal.edu.co/bitstream/unal/85563/2/1026286522.2024.pdf9b377ede8bed883d39e8bc52a3c60987MD52THUMBNAIL1026286522.2024.pdf.jpg1026286522.2024.pdf.jpgGenerated Thumbnailimage/jpeg4655https://repositorio.unal.edu.co/bitstream/unal/85563/3/1026286522.2024.pdf.jpg91b35c752ff9ec029d1677ee77358485MD53unal/85563oai:repositorio.unal.edu.co:unal/855632024-01-31 23:08:58.123Repositorio Institucional Universidad Nacional de Colombiarepositorio_nal@unal.edu.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

Rasgos de personalidad y su asociación con síntomas de ansiedad y depresión en paciente con cáncer

Publicaciones similares