Efecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinos
Ilustraciones, tablas
- Autores:
-
Amaya Barragán, Lina Marcela
- Tipo de recurso:
- Fecha de publicación:
- 2021
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/80346
- Palabra clave:
- 630 - Agricultura y tecnologías relacionadas
Extractos de hoja
Extractos vegetales
Antioxidantes
Moringa
blastocisto
Biotecnología
Estrés oxidativo
Planta medicinal
Ganado vacuno
blastocyst
biotechnology
oxidative stress
medicinal plant
cattle
- Rights
- openAccess
- License
- Reconocimiento 4.0 Internacional
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| dc.title.spa.fl_str_mv |
Efecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinos |
| dc.title.translated.eng.fl_str_mv |
Antioxidant effect of Moringa oleifera extract in the in vitro maturation of bovine oocytes |
| title |
Efecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinos |
| spellingShingle |
Efecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinos 630 - Agricultura y tecnologías relacionadas Extractos de hoja Extractos vegetales Antioxidantes Moringa blastocisto Biotecnología Estrés oxidativo Planta medicinal Ganado vacuno blastocyst biotechnology oxidative stress medicinal plant cattle |
| title_short |
Efecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinos |
| title_full |
Efecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinos |
| title_fullStr |
Efecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinos |
| title_full_unstemmed |
Efecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinos |
| title_sort |
Efecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinos |
| dc.creator.fl_str_mv |
Amaya Barragán, Lina Marcela |
| dc.contributor.advisor.none.fl_str_mv |
Torres Osorio, Viviana Campos Gaona, Rómulo |
| dc.contributor.author.none.fl_str_mv |
Amaya Barragán, Lina Marcela |
| dc.contributor.datacurator.none.fl_str_mv |
Vélez, Mauricio |
| dc.contributor.researchgroup.spa.fl_str_mv |
Conservación, Mejoramiento y Utilización del Ganado Criollo Hartón del Valle y Otros Recursos Genéticos Animales en el Sur Occidente Colombiano |
| dc.contributor.subjectmatterexpert.none.fl_str_mv |
Torres Castañeda, Harlen Urrego, Rodrigo |
| dc.subject.ddc.spa.fl_str_mv |
630 - Agricultura y tecnologías relacionadas |
| topic |
630 - Agricultura y tecnologías relacionadas Extractos de hoja Extractos vegetales Antioxidantes Moringa blastocisto Biotecnología Estrés oxidativo Planta medicinal Ganado vacuno blastocyst biotechnology oxidative stress medicinal plant cattle |
| dc.subject.agrovoc.none.fl_str_mv |
Extractos de hoja Extractos vegetales Antioxidantes Moringa |
| dc.subject.proposal.spa.fl_str_mv |
blastocisto Biotecnología Estrés oxidativo Planta medicinal Ganado vacuno |
| dc.subject.proposal.eng.fl_str_mv |
blastocyst biotechnology oxidative stress medicinal plant cattle |
| description |
Ilustraciones, tablas |
| publishDate |
2021 |
| dc.date.accessioned.none.fl_str_mv |
2021-09-30T20:11:57Z |
| dc.date.available.none.fl_str_mv |
2021-09-30T20:11:57Z |
| dc.date.issued.none.fl_str_mv |
2021 |
| dc.type.spa.fl_str_mv |
Trabajo de grado - Maestría |
| dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/masterThesis |
| dc.type.coarversion.spa.fl_str_mv |
http://purl.org/coar/version/c_e19f295774971610 |
| dc.type.content.spa.fl_str_mv |
Text |
| dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/TM |
| dc.identifier.uri.none.fl_str_mv |
https://repositorio.unal.edu.co/handle/unal/80346 |
| dc.identifier.instname.spa.fl_str_mv |
Universidad Nacional de Colombia |
| dc.identifier.reponame.spa.fl_str_mv |
Repositorio Institucional Universidad Nacional de Colombia |
| dc.identifier.repourl.spa.fl_str_mv |
https://repositorio.unal.edu.co/ |
| url |
https://repositorio.unal.edu.co/handle/unal/80346 https://repositorio.unal.edu.co/ |
| identifier_str_mv |
Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
| dc.language.iso.spa.fl_str_mv |
spa |
| language |
spa |
| dc.relation.references.spa.fl_str_mv |
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Reconocimiento 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Torres Osorio, Viviana8a0c9bca367e01ac8a0ea640c8eb7685Campos Gaona, Rómulof8816487732e56dd010acaeeb7d6bfdaAmaya Barragán, Lina Marcela148fb455d0420929b8e361a76be7d24dVélez, MauricioConservación, Mejoramiento y Utilización del Ganado Criollo Hartón del Valle y Otros Recursos Genéticos Animales en el Sur Occidente ColombianoTorres Castañeda, HarlenUrrego, Rodrigo2021-09-30T20:11:57Z2021-09-30T20:11:57Z2021https://repositorio.unal.edu.co/handle/unal/80346Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/Ilustraciones, tablasLas hojas de Moringa oleifera tienen compuestos como vitaminas, minerales y metabolitos secundarios que le confieren propiedades antioxidantes. Sin embargo, el extracto de esta planta no ha sido estudiado como suplemento en los medios de cultivo en la producción in vitro de embriones bovinos. Por tanto, el objetivo fue evaluar si el medio de maduración in vitro con extracto de Moringa oleifera mejora la competencia del oocito y la calidad del blastocisto, a través de la tasa de maduración nuclear, tasa de blastocistos totales, niveles de especies reactivas de oxígeno (EROs), niveles de glutatión (GSH) intracelular y número de células totales. La extracción fitoquímica se realizó a partir de hojas maduras de Moringa oleifera. Los oocitos provenientes de ovarios de una planta de beneficio (1446) se maduraron en medio TCM 199 suplementado con 0 (control- , C), 50, 100 y 150 μg mL1 de extracto de Moringa oleifera y 50 μg mL-1 de ácido ascórbico (Control+ , AA). Pasadas 24 horas, se fertilizaron y cultivaron de acuerdo con el procedimiento estándar. Los datos obtenidos fueron analizados con la prueba Kruskal-Wallis. No se observaron diferencias significativas entre tratamientos (P>0,05), a excepción de los niveles de GSH y EROs, que se redujeron un 59% y 57%, respectivamente, con el uso de 150 μg mL-1 de extracto. En conclusión, el extracto de Moringa oleifera redujo las EROs, sin embargo las concentraciones de GSH intracelular también se redujeron y no hubo un efecto significativo en la maduración in vitro de oocitos bovinos ni en el desarrollo embrionario temprano. (Texto tomado de la fuente)Moringa oleifera leaves have compounds such as vitamins, minerals and secondary metabolites that give it antioxidant properties. However, the extract of this plant has not been studied as a supplement in culture media in the in vitro production of bovine embryos. Therefore, the objective was to evaluate whether the in vitro maturation medium with Moringa oleifera extract improves oocyte competence and blastocyst quality, through the nuclear maturation rate, total blastocyst rate, levels of reactive oxygen species. (ROS), intracellular glutathione (GSH) levels and total cell number. The phytochemical extraction was carried out from mature leaves of Moringa oleifera. The oocytes from ovaries of a beneficiation plant (1446) were matured in TCM 199 medium supplemented with 0 (control- , C), 50, 100 and 150 μg mL-1 of Moringa oleifera extract and 50 μg mL-1 of ascorbic acid (Control + , AA). After 24 hours, they were fertilized and cultivated according to the standard procedure. The data obtained were analyzed with the Kruskal-Wallis test. No significant differences were observed between treatments (P> 0.05), with the exception of GSH and ROS levels, which were reduced by 59% and 57%, respectively, with the use of 150 μg mL-1 of extract. In conclusion, Moringa oleifera extract reduced ROS, however intracellular GSH concentrations were also reduced and there was no significant effect on in vitro maturation of bovine oocytes or early embryonic developmentMaestríaMagíster en Ciencias Agrarias1. Obtención del extracto de hojas de Moringa oleifera 2. Fraccionamiento del extracto 3. Análisis fitoquímico preliminar 4. Determinación colorimétrica a microescala de compuestos fenólicos 5. Contenido total de fenoles (CTF) 6. Contenido de Flavonoides Totales (CFT) 7.Contenido total de catequinas (CTC) 8. Determinación de la actividad antioxidante (DPPH, FRAP, ABTS) 9. Recolección de ovarios 10. Aspiración folicular y obtención de oocitos 11. Maduración in vitro (MIV) 12. Fertilización in vitro (FIV) 13. Cultivo in vitro (CIV) 14. Evaluación de la maduración nuclear 15. Evaluación de los niveles de EROs y GSH intracelulares 16. Evaluación de la calidad embrionariaProducción animal tropical85 páginasapplication/pdfspaUniversidad Nacional de ColombiaPalmira - Ciencias Agropecuarias - Maestría en Ciencias AgrariasFacultad de Ciencias AgropecuariasUniversidad Nacional de Colombia - Sede Palmira630 - Agricultura y tecnologías relacionadasExtractos de hojaExtractos vegetalesAntioxidantesMoringablastocistoBiotecnologíaEstrés oxidativoPlanta medicinalGanado vacunoblastocystbiotechnologyoxidative stressmedicinal plantcattleEfecto antioxidante del extracto de Moringa oleifera en la maduración in vitro de oocitos bovinosAntioxidant effect of Moringa oleifera extract in the in vitro maturation of bovine oocytesTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesishttp://purl.org/coar/version/c_e19f295774971610http://purl.org/coar/version/c_970fb48d4fbd8a85Texthttp://purl.org/redcol/resource_type/TMAbdel Fattah, M. E., Sobhy, H. M., Reda, A., & Abdelrazek, H. M. A. (2020). 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Journal of Integrative Agriculture, 12(10), 1826–1838. https://doi.org/10.1016/S2095-3119(13)60412-8Universidad Nacional de ColombiaEstudiantesInvestigadoresLICENSElicense.txtlicense.txttext/plain; charset=utf-83964https://repositorio.unal.edu.co/bitstream/unal/80346/1/license.txtcccfe52f796b7c63423298c2d3365fc6MD51ORIGINAL1113669612.2021.pdf1113669612.2021.pdfTesis de Maestría en Ciencias Agrariasapplication/pdf1497104https://repositorio.unal.edu.co/bitstream/unal/80346/3/1113669612.2021.pdf9ee18390abc47400c70b656f9d66e8c8MD53THUMBNAIL1113669612.2021.pdf.jpg1113669612.2021.pdf.jpgGenerated Thumbnailimage/jpeg4981https://repositorio.unal.edu.co/bitstream/unal/80346/4/1113669612.2021.pdf.jpg7d115b47719c76ea4e91341b4ce68ac2MD54unal/80346oai:repositorio.unal.edu.co:unal/803462024-07-30 23:10:42.669Repositorio Institucional Universidad Nacional de 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