Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu

ilustraciones

Autores:: Castellanos Castellanos, Deisy Nataly

Tipo de recurso:

Fecha de publicación:: 2023

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:: spa

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repository_id_str
dc.title.spa.fl_str_mv	Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu
dc.title.translated.eng.fl_str_mv	Evaluation of spect/ct image quality in post-therapy rastrays with 131i and 131I y 177Lu
title	Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu
spellingShingle	Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu Próstata Medicina nuclear Prostate Nuclear Medicine Terapias metabólicas Calidad de la imagen SPECT/CT Medicina Nuclear Rastreos post-terapia Colimadores Metabolic therapies Image quality SPECT/CT Nuclear Medicine Post-therapy Rastray Collimators
title_short	Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu
title_full	Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu
title_fullStr	Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu
title_full_unstemmed	Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu
title_sort	Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu
dc.creator.fl_str_mv	Castellanos Castellanos, Deisy Nataly
dc.contributor.advisor.none.fl_str_mv	Barbosa Parada, Nathaly Plazas de Pinzon, Maria Cristina
dc.contributor.author.none.fl_str_mv	Castellanos Castellanos, Deisy Nataly
dc.contributor.orcid.spa.fl_str_mv	https://orcid.org/0000-0003-1317-7289
dc.contributor.cvlac.spa.fl_str_mv	https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000098087
dc.subject.decs.spa.fl_str_mv	Próstata Medicina nuclear
topic	Próstata Medicina nuclear Prostate Nuclear Medicine Terapias metabólicas Calidad de la imagen SPECT/CT Medicina Nuclear Rastreos post-terapia Colimadores Metabolic therapies Image quality SPECT/CT Nuclear Medicine Post-therapy Rastray Collimators
dc.subject.decs.eng.fl_str_mv	Prostate Nuclear Medicine
dc.subject.proposal.spa.fl_str_mv	Terapias metabólicas Calidad de la imagen SPECT/CT Medicina Nuclear Rastreos post-terapia Colimadores
dc.subject.proposal.eng.fl_str_mv	Metabolic therapies Image quality SPECT/CT Nuclear Medicine Post-therapy Rastray Collimators
description	ilustraciones
publishDate	2023
dc.date.accessioned.none.fl_str_mv	2023-07-07T15:14:28Z
dc.date.available.none.fl_str_mv	2023-07-07T15:14:28Z
dc.date.issued.none.fl_str_mv	2023-06-06
dc.type.spa.fl_str_mv	Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/masterThesis
dc.type.version.spa.fl_str_mv	info:eu-repo/semantics/acceptedVersion
dc.type.content.spa.fl_str_mv	Text
dc.type.redcol.spa.fl_str_mv	http://purl.org/redcol/resource_type/TM
status_str	acceptedVersion
dc.identifier.uri.none.fl_str_mv	https://repositorio.unal.edu.co/handle/unal/84163
dc.identifier.instname.spa.fl_str_mv	Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv	https://repositorio.unal.edu.co/
url	https://repositorio.unal.edu.co/handle/unal/84163 https://repositorio.unal.edu.co/
identifier_str_mv	Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv	spa
language	spa
dc.relation.references.spa.fl_str_mv	Rachel A Powsner, Matthew R Palmer, and Edward R Powsner. Essentials of nuclear medicine physics and instrumentation. John Wiley & Sons, 2013. Ashutosh Dash, Maroor Raghavan Ambikalmajan Pillai, and Furn F Knapp. Production of 177lu for targeted radionuclide therapy: available options. Nuclear medicine and molecular imaging, 49(2):85–107, 2015. Ervin B Podgorsak. Radiation physics for medical physicists. Springer, 2006 David Dowsett, Patrick A Kenny, and R Eugene Johnston. The physics of diagnostic imaging. CRC Press, 2006. Gabriela Kramer-Marek and Jacek Capala. The role of nuclear medicine in modern therapy of cancer. Tumor Biology, 33(3):629–640, 2012. Yuni K Dewaraja, Eric C Frey, George Sgouros, A Bertrand Brill, Peter Roberson, Pat B Zanzonico, and Michael Ljungberg. Mird pamphlet no. 23: quantitative spect for patient- specific 3-dimensional dosimetry in internal radionuclide therapy. Journal of Nuclear Medicine, 53(8):1310–1325, 2012. Simon R Cherry, James A Sorenson, and Michael E Phelps. Physics in nuclear medicine e-Book. Elsevier Health Sciences, 2012. HEALTH SAFETY GUIDELINE ENVIRONMENTAL. Radiation Safety Service: Iodine-131. University Of Michigan, 2020. Hojjat Ahmadzadehfar, Hans-J ̈urgen Biersack, Leonard M Freeman, and Lionel S Zuckier. Clinical nuclear medicine. Springer Nature, 2020. GE Healthcare. Discovery nm/ct 670, 2011. Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, and Freddie Bray. Global cancer statistics 2020: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians, 71(3):209–249, 2021. Luca Filippi, Agostino Chiaravalloti, Orazio Schillaci, Roberto Cianni, and Oreste Bagni. Theranostic approaches in nuclear medicine: Current status and future prospects. Expert review of medical devices, 17(4):331–343, 2020. Nasim Vahidfar, Elisabeth Eppard, Saeed Farzanehfar, Anna Yordanova, Maryam Fallahpoor, and Hojjat Ahmadzadehfar. An impressive approach in nuclear medicine: Theranostics. PET clinics, 16(3):327–340, 2021. M D’Arienzo, M Cazzato, ML Cozzella, M Cox, Marco D’Andrea, A Fazio, A Fenwick, G Iaccarino, L Johansson, Lidia Strigari, et al. Gamma camera calibration and validation for quantitative spect imaging with 177lu. Applied Radiation and Isotopes, 112:156164, 2016. Michael Ljungberg, Anna Celler, Mark W Konijnenberg, Keith F Eckerman, Yuni K Dewaraja, and Katarina Sj ̈ogreen-Gleisner. Mird pamphlet no. 26: joint eanm/mird guidelines for quantitative 177lu spect applied for dosimetry of radiopharmaceutical therapy. Journal of nuclear medicine, 57(1):151–162, 2016. Lidia Strigari, Mark Konijnenberg, Carlo Chiesa, Manuel Bardies, Yong Du, Katarina Sj ̈ogreen Gleisner, Michael Lassmann, and Glenn Flux. The evidence base for the use of internal dosimetry in the clinical practice of molecular radiotherapy. European journal of nuclear medicine and molecular imaging, 41(10):1976–1988, 2014. Richard L Wahl, George Sgouros, Amir Iravani, Heather Jacene, Daniel Pryma, Babak Saboury, Jacek Capala, and Stephen A Graves. Normal-tissue tolerance to radiopharmaceutical therapies, the knowns and the unknowns. Journal of Nuclear Medicine, 62 (Supplement 3):23S–35S, 2021. Else A Aalbersberg, Daphne de Vries-Huizing, Margot ET Tesselaar, Marcel PM Stokkel, and Michelle WJ Versleijen. Post-prrt scans: which scans to make and what to look for. Cancer Imaging, 22(1):1–8, 2022. Alejandro Perera Pintado, Leonel A Torres Aroche, Alex Vergara Gil, Juan F Batista Cu ́ellar, and Analis ́ıs Prats Capote. Spect/ct: principales aplicaciones en la medicina nuclear. Nucleus, (62):2–9, 2017. Masato Kobayashi, Hiroshi Wakabayashi, Daiki Kayano, Takahiro Konishi, Hironori Kojima, Hiroto Yoneyama, Koichi Okuda, Hiroyuki Tsushima, Masahisa Onoguchi, Keiichi Kawai, et al. Application of a medium-energy collimator for i-131 imaging after ablation treatment of differentiated thyroid cancer. Annals of nuclear medicine, 28(6):551–558, 2014. Anna Yordanova, Elisabeth Eppard, Stefan K ̈urpig, Ralph A Bundschuh, Stefan Schonberger, Maria Gonzalez-Carmona, Georg Feldmann, Hojjat Ahmadzadehfar, and Markus Essler. Theranostics in nuclear medicine practice. OncoTargets and therapy, 10:4821, 2017. Hojjat Ahmadzadehfar. Targeted therapy for metastatic prostate cancer with radionuclides. Prostate Cancer–Leading–Edge Diagnostic Procedures and Treatments, pages 60–4, 2016. Serengulam V Govindan, Gary L Griffiths, Hans J Hansen, Ivan D Horak, and David M Goldenberg. Cancer therapy with radiolabeled and drug/toxin-conjugated antibodies. Technology in cancer research & treatment, 4(4):375–391, 2005. Abdelhamid H Elgazzar. The pathophysiologic basis of nuclear medicine. Springer Science Business Media, 2006. Anna Wyszomirska. Iodine-131 for therapy of thyroid diseases. physical and biological basis. Nuclear Medicine Review, 15(2):120–123, 2012. Ludwike WM van Kalmthout, Esm ́ee CA van der Sar, Arthur JAT Braat, Bart de Keizer, and Marnix GEH Lam. Lutetium-177-psma therapy for prostate cancer patients—a brief overview of the literature. Tijdschrift voor Urologie, 10(6):141–146, 2020. Ferdinando Calabria and Orazio Schillaci. Radiopharmaceuticals. Springer, 2020. Kenyoung Kim and Seong-Jang Kim. Lu-177-based peptide receptor radionuclide therapy for advanced neuroendocrine tumors. Nuclear medicine and molecular imaging, 52(3):208–215, 2018. Richard B Firestone, SY Chu, and Coral M Baglin. of the table of isotopes: 1998 update. In APS Division of Nuclear Physics Meeting Abstracts, pages BD–11, 1997. FF Knapp Jr, S Mirzadeh, AL Beets, and M Du. Production of therapeutic radioisotopes in the ornl high flux isotope reactor (hfir) for applications in nuclear medicine, oncologyand interventional cardiology. Journal of radioanalytical and nuclear chemistry, 263(2):503– 509, 2005. Jeong Won Lee, Sang Mi Lee, Gwan Pyo Koh, and Dae Ho Lee. The comparison of 131i whole-body scans on the third and tenth day after 131i therapy in patients with well-differentiated thyroid cancer: preliminary report. Annals of nuclear medicine, 25(6): 439–446, 2011. Ari Chong, Ho-Chun Song, Jung-Joon Min, Shin Young Jeong, Jung-Min Ha, Jahae Kim, Su-Ung Yoo, Jong-Ryool Oh, and Hee-Seung Bom. Improved detection of lung or bone metastases with an i-131 whole body scan on the 7th day after high-dose i-131 therapy in patients with thyroid cancer. Nuclear Medicine and Molecular Imaging, 44(4):273–281, 2010. Angela Spanu, Maria E Solinas, Francesca Chessa, Daniela Sanna, Susanna Nuvoli, and Giuseppe Madeddu. 131i spect/ct in the follow-up of differentiated thyroid carcinoma: incremental value versus planar imaging. Journal of Nuclear Medicine, 50(2):184–190, 2009. Frank Herbert Attix. Introduction to radiological physics and radiation dosimetry. John Wiley & Sons, 2008. James E Turner. Atoms, radiation, and radiation protection. John Wiley & Sons, 2008. Faiz M Khan and John P Gibbons. Khan’s the physics of radiation therapy. Lippincott Williams & Wilkins, 2014. ulong Yan and Eduardo G Moros. Radiation oncology physics: A handbook for teachers and students, eb podgorsak (ed.), international atomic energy association, vienna, austria (2005), 657 pages, euro 65, paperbound, isbn 92-0-107304-6, 2006. Michael Ljungberg. Handbook of Nuclear Medicine and Molecular Imaging for Physicists: Instrumentation and Imaging Procedures, Volume I. CRC Press, 2022. Syed Naeem Ahmed. Physics and engineering of radiation detection. Academic Press, 2007. jennifer Prekeges. Nuclear Medicine Instrumentation (book). Jones & Bartlett Publishers, 2012. Philippe P Bruyant. Analytic and iterative reconstruction algorithms in spect. Journal of Nuclear Medicine, 43(10):1343–1358, 2002. James A Patton and Timothy G Turkington. Spect/ct physical principles and attenuation correction. Journal of nuclear medicine technology, 36(1):1–10, 2008. Jerry L Prince and Jonathan M Links. Medical imaging signals and systems, volume 37. Pearson Prentice Hall Upper Saddle River, 2006. Richard L Van Metter. Handbook of medical imaging, volume 1. Physics and psychophysics, 2000. Albert Rose. The sensitivity performance of the human eye on an absolute scale. JOSA, 38(2):196–208, 1948. Louis Sibille, Benjamin Chambert, Sandrine Alonso, Corinne Barrau, Emmanuel D’Estanque, Yassine Al Tabaa, Laurent Collombier, Christophe Demattei, Pierre-Olivier Kotzki, and Vincent Boudousq. Impact of the adaptive statistical iterative reconstruction technique on radiation dose and image quality in bone spect/ct. Journal of Nuclear Medicine, 57(7):1091–1095, 2016. Johannes Schindelin, Curtis T Rueden, Mark C Hiner, and Kevin W Eliceiri. The imagej ecosystem: An open platform for biomedical image analysis. Molecular reproduction and development, 82(7-8):518–529, 2015. Marcin Wojdyr. Fityk: a general-purpose peak fitting program. Journal of applied crystallography, 43(5-1):1126–1128, 2010. Mansour M Alqahtani, Kathy P Willowson, Chris Constable, Roger Fulton, and Peter L Kench. Optimization of 99mtc wholebody spect/ct image quality: A phantom study. Journal of Applied Clinical Medical Physics, 23(4):e13528, 2022. Silje Kjærnes Øen, Lars Birger Aasheim, Live Eikenes, and Anna Maria Karlberg. Image quality and detectability in siemens biograph pet/mri and pet/ct systems—a phantom study. EJNMMI physics, 6:1–16, 2019. Wesley Wooten and Tri Tran. Megp vs hegp collimator for i-131 thyroid scintigraphy, 2010. Masato Kobayashi, Hiroshi Wakabayashi, Daiki Kayano, Koudai Nishi, Masahisa Onoguchi, Keiichi Kawai, and Seigo Kinuya. Comparison between a high-and medium-energy collimator for na131i imaging of differentiated thyroid cancer, 2013.
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dc.publisher.spa.fl_str_mv	Universidad Nacional de Colombia
dc.publisher.program.spa.fl_str_mv	Bogotá - Ciencias - Maestría en Física Médica
dc.publisher.faculty.spa.fl_str_mv	Facultad de Ciencias
dc.publisher.place.spa.fl_str_mv	Bogotá,Colombia
dc.publisher.branch.spa.fl_str_mv	Universidad Nacional de Colombia - Sede Bogotá
institution	Universidad Nacional de Colombia
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spelling	Reconocimiento 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Barbosa Parada, Nathaly0c6572d2dff251068726d15e0c282dc2Plazas de Pinzon, Maria Cristinaf0881dc4c133b89730196b3918379074Castellanos Castellanos, Deisy Natalycaf309136f56b97bf05431e91828044ahttps://orcid.org/0000-0003-1317-7289https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=00000980872023-07-07T15:14:28Z2023-07-07T15:14:28Z2023-06-06https://repositorio.unal.edu.co/handle/unal/84163Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustracionesUn método muy utilizado en los últimos años debido a sus excelentes resultados para tratar tumores neuroendocrinos, cáncer de próstata metástasis resistente a la castración y cáncer de tiroides es el teragnóstico, un ́área de la medicina nuclear que emplea moléculas unidas a radionúclidos y que combina el diagnóstico y la terapia dirigida específica para lograr un tratamiento personalizado para el paciente. Se conoce la terapia con yodo radiactivo I-131 para tratar el carcinoma diferenciado de tiroides y el radioisótopo Lu-177 para tratar tumores neuroendocrinos y cáncer de próstata resistente a la castración. Debido a las características físicas de estos radionuclidos, ya que son emisores de radiación gamma y beta, mediante las emisiones gamma es posible obtener imágenes posteriores a la terapia conocidas como rastreo posterapia, que nos da información de la biodistribución del radiofármaco y estimar la respuesta exitosa de la terapia. En el presente trabajo se evalúa la calidad de la imagen de rastreos Post-terapia I-131 cuando se utilizan colimadores HEGP y MEGP para imágenes I-131 post-terapia utilizando un fantoma y un protocolo clínico de adquisición y reconstrucción. El trabajo se limita al análisis de imagen SPECT de I-131, ya que en los meses precedentes a esta entrega se da un desabastecimiento de Lu-177 a nivel global, producto de la falla que presentó uno de los reactores que producen este radioisótopo. (Texto tomado de la fuente)A method widely used in recent years due to its excellent results in treating neuroendocrine tumors, metastatic castration-resistant prostate cancer and thyroid cancer is teragnostics, an area of nuclear medicine that uses molecules bound to radionuclides and combines diagnosis and targeted therapy to achieve a personalized treatment for the patient. Radioactive iodine I-131 therapy is known to treat differentiated thyroid carcinoma and the radioisotope Lu-177 to treat neuroendocrine tumors and castration-resistant prostate cancer. Due to the physical characteristics of these radionuclides, since they are emitters of gamma and beta radiation, by means of gamma emissions it is possible to obtain post-therapy images known as post-therapy tracking, which gives us information on the biodistribution of the radiopharmaceutical and to estimate the successful response of the therapy. In the present work we evaluate the image quality of I-131 post-therapy tracings when using HEGP and MEGP collimators for I-131 post-therapy imaging using a phantom and a clinical acquisition and reconstruction protocol. The work is limited to SPECT image analysis of I-131, since in the months preceding this delivery there was a global shortage of Lu-177, due to the failure of one of the reactors that produce this radioisotope.MaestríaMagíster en Física MédicaFísica Medica/Medicina Nuclear60 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Ciencias - Maestría en Física MédicaFacultad de CienciasBogotá,ColombiaUniversidad Nacional de Colombia - Sede BogotáEvaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177LuEvaluation of spect/ct image quality in post-therapy rastrays with 131i and 131I y 177LuTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMRachel A Powsner, Matthew R Palmer, and Edward R Powsner. Essentials of nuclear medicine physics and instrumentation. John Wiley & Sons, 2013.Ashutosh Dash, Maroor Raghavan Ambikalmajan Pillai, and Furn F Knapp. Production of 177lu for targeted radionuclide therapy: available options. Nuclear medicine and molecular imaging, 49(2):85–107, 2015.Ervin B Podgorsak. Radiation physics for medical physicists. Springer, 2006David Dowsett, Patrick A Kenny, and R Eugene Johnston. The physics of diagnostic imaging. CRC Press, 2006.Gabriela Kramer-Marek and Jacek Capala. The role of nuclear medicine in modern therapy of cancer. Tumor Biology, 33(3):629–640, 2012.Yuni K Dewaraja, Eric C Frey, George Sgouros, A Bertrand Brill, Peter Roberson, Pat B Zanzonico, and Michael Ljungberg. Mird pamphlet no. 23: quantitative spect for patient- specific 3-dimensional dosimetry in internal radionuclide therapy. Journal of Nuclear Medicine, 53(8):1310–1325, 2012.Simon R Cherry, James A Sorenson, and Michael E Phelps. Physics in nuclear medicine e-Book. Elsevier Health Sciences, 2012.HEALTH SAFETY GUIDELINE ENVIRONMENTAL. Radiation Safety Service: Iodine-131. University Of Michigan, 2020.Hojjat Ahmadzadehfar, Hans-J ̈urgen Biersack, Leonard M Freeman, and Lionel S Zuckier. Clinical nuclear medicine. Springer Nature, 2020.GE Healthcare. Discovery nm/ct 670, 2011.Hyuna Sung, Jacques Ferlay, Rebecca L Siegel, Mathieu Laversanne, Isabelle Soerjomataram, Ahmedin Jemal, and Freddie Bray. Global cancer statistics 2020: Globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians, 71(3):209–249, 2021.Luca Filippi, Agostino Chiaravalloti, Orazio Schillaci, Roberto Cianni, and Oreste Bagni. Theranostic approaches in nuclear medicine: Current status and future prospects. Expert review of medical devices, 17(4):331–343, 2020.Nasim Vahidfar, Elisabeth Eppard, Saeed Farzanehfar, Anna Yordanova, Maryam Fallahpoor, and Hojjat Ahmadzadehfar. An impressive approach in nuclear medicine: Theranostics. PET clinics, 16(3):327–340, 2021.M D’Arienzo, M Cazzato, ML Cozzella, M Cox, Marco D’Andrea, A Fazio, A Fenwick, G Iaccarino, L Johansson, Lidia Strigari, et al. Gamma camera calibration and validation for quantitative spect imaging with 177lu. Applied Radiation and Isotopes, 112:156164, 2016.Michael Ljungberg, Anna Celler, Mark W Konijnenberg, Keith F Eckerman, Yuni K Dewaraja, and Katarina Sj ̈ogreen-Gleisner. Mird pamphlet no. 26: joint eanm/mird guidelines for quantitative 177lu spect applied for dosimetry of radiopharmaceutical therapy. Journal of nuclear medicine, 57(1):151–162, 2016.Lidia Strigari, Mark Konijnenberg, Carlo Chiesa, Manuel Bardies, Yong Du, Katarina Sj ̈ogreen Gleisner, Michael Lassmann, and Glenn Flux. The evidence base for the use of internal dosimetry in the clinical practice of molecular radiotherapy. European journal of nuclear medicine and molecular imaging, 41(10):1976–1988, 2014.Richard L Wahl, George Sgouros, Amir Iravani, Heather Jacene, Daniel Pryma, Babak Saboury, Jacek Capala, and Stephen A Graves. Normal-tissue tolerance to radiopharmaceutical therapies, the knowns and the unknowns. Journal of Nuclear Medicine, 62 (Supplement 3):23S–35S, 2021.Else A Aalbersberg, Daphne de Vries-Huizing, Margot ET Tesselaar, Marcel PM Stokkel, and Michelle WJ Versleijen. Post-prrt scans: which scans to make and what to look for. Cancer Imaging, 22(1):1–8, 2022.Alejandro Perera Pintado, Leonel A Torres Aroche, Alex Vergara Gil, Juan F Batista Cu ́ellar, and Analis ́ıs Prats Capote. Spect/ct: principales aplicaciones en la medicina nuclear. Nucleus, (62):2–9, 2017.Masato Kobayashi, Hiroshi Wakabayashi, Daiki Kayano, Takahiro Konishi, Hironori Kojima, Hiroto Yoneyama, Koichi Okuda, Hiroyuki Tsushima, Masahisa Onoguchi, Keiichi Kawai, et al. Application of a medium-energy collimator for i-131 imaging after ablation treatment of differentiated thyroid cancer. Annals of nuclear medicine, 28(6):551–558, 2014.Anna Yordanova, Elisabeth Eppard, Stefan K ̈urpig, Ralph A Bundschuh, Stefan Schonberger, Maria Gonzalez-Carmona, Georg Feldmann, Hojjat Ahmadzadehfar, and Markus Essler. Theranostics in nuclear medicine practice. OncoTargets and therapy, 10:4821, 2017.Hojjat Ahmadzadehfar. Targeted therapy for metastatic prostate cancer with radionuclides. Prostate Cancer–Leading–Edge Diagnostic Procedures and Treatments, pages 60–4, 2016.Serengulam V Govindan, Gary L Griffiths, Hans J Hansen, Ivan D Horak, and David M Goldenberg. Cancer therapy with radiolabeled and drug/toxin-conjugated antibodies. Technology in cancer research & treatment, 4(4):375–391, 2005.Abdelhamid H Elgazzar. The pathophysiologic basis of nuclear medicine. Springer Science Business Media, 2006.Anna Wyszomirska. Iodine-131 for therapy of thyroid diseases. physical and biological basis. Nuclear Medicine Review, 15(2):120–123, 2012.Ludwike WM van Kalmthout, Esm ́ee CA van der Sar, Arthur JAT Braat, Bart de Keizer, and Marnix GEH Lam. Lutetium-177-psma therapy for prostate cancer patients—a brief overview of the literature. Tijdschrift voor Urologie, 10(6):141–146, 2020.Ferdinando Calabria and Orazio Schillaci. Radiopharmaceuticals. Springer, 2020.Kenyoung Kim and Seong-Jang Kim. Lu-177-based peptide receptor radionuclide therapy for advanced neuroendocrine tumors. Nuclear medicine and molecular imaging, 52(3):208–215, 2018.Richard B Firestone, SY Chu, and Coral M Baglin. of the table of isotopes: 1998 update. In APS Division of Nuclear Physics Meeting Abstracts, pages BD–11, 1997.FF Knapp Jr, S Mirzadeh, AL Beets, and M Du. Production of therapeutic radioisotopes in the ornl high flux isotope reactor (hfir) for applications in nuclear medicine, oncologyand interventional cardiology. Journal of radioanalytical and nuclear chemistry, 263(2):503– 509, 2005.Jeong Won Lee, Sang Mi Lee, Gwan Pyo Koh, and Dae Ho Lee. The comparison of 131i whole-body scans on the third and tenth day after 131i therapy in patients with well-differentiated thyroid cancer: preliminary report. Annals of nuclear medicine, 25(6): 439–446, 2011.Ari Chong, Ho-Chun Song, Jung-Joon Min, Shin Young Jeong, Jung-Min Ha, Jahae Kim, Su-Ung Yoo, Jong-Ryool Oh, and Hee-Seung Bom. Improved detection of lung or bone metastases with an i-131 whole body scan on the 7th day after high-dose i-131 therapy in patients with thyroid cancer. Nuclear Medicine and Molecular Imaging, 44(4):273–281, 2010.Angela Spanu, Maria E Solinas, Francesca Chessa, Daniela Sanna, Susanna Nuvoli, and Giuseppe Madeddu. 131i spect/ct in the follow-up of differentiated thyroid carcinoma: incremental value versus planar imaging. Journal of Nuclear Medicine, 50(2):184–190, 2009.Frank Herbert Attix. Introduction to radiological physics and radiation dosimetry. John Wiley & Sons, 2008.James E Turner. Atoms, radiation, and radiation protection. John Wiley & Sons, 2008.Faiz M Khan and John P Gibbons. Khan’s the physics of radiation therapy. Lippincott Williams & Wilkins, 2014.ulong Yan and Eduardo G Moros. Radiation oncology physics: A handbook for teachers and students, eb podgorsak (ed.), international atomic energy association, vienna, austria (2005), 657 pages, euro 65, paperbound, isbn 92-0-107304-6, 2006.Michael Ljungberg. Handbook of Nuclear Medicine and Molecular Imaging for Physicists: Instrumentation and Imaging Procedures, Volume I. CRC Press, 2022.Syed Naeem Ahmed. Physics and engineering of radiation detection. Academic Press, 2007.jennifer Prekeges. Nuclear Medicine Instrumentation (book). Jones & Bartlett Publishers, 2012.Philippe P Bruyant. Analytic and iterative reconstruction algorithms in spect. 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Comparison between a high-and medium-energy collimator for na131i imaging of differentiated thyroid cancer, 2013.PróstataMedicina nuclearProstateNuclear MedicineTerapias metabólicasCalidad de la imagenSPECT/CTMedicina NuclearRastreos post-terapiaColimadoresMetabolic therapiesImage qualitySPECT/CTNuclear MedicinePost-therapy RastrayCollimatorsEstudiantesInvestigadoresLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/84163/3/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD53ORIGINAL1049650033.2023.pdf1049650033.2023.pdfTesis de Maestría en Física Médicaapplication/pdf4290014https://repositorio.unal.edu.co/bitstream/unal/84163/4/1049650033.2023.pdf3ec7c4c1a122847196716f26672fc695MD54THUMBNAIL1049650033.2023.pdf.jpg1049650033.2023.pdf.jpgGenerated 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Evaluación de la calidad de la imagen de spect/ct en rastreos posterapia con 131I y 177Lu

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