Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros
ilustraciones, diagramas, fotografías
- Autores:
-
Carrillo Torres, Adriana Carolina
- Tipo de recurso:
- Fecha de publicación:
- 2023
- Institución:
- Universidad Nacional de Colombia
- Repositorio:
- Universidad Nacional de Colombia
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.unal.edu.co:unal/85886
- Palabra clave:
- 630 - Agricultura y tecnologías relacionadas::636 - Producción animal
Enfermedades de los animales
Rebaño de leche
Enfermedades respiratorias
animal diseases
dairy herds
respiratory diseases
Enfermedad respiratoria bovina
Enfermedad respiratoria de los terneros
Enfermedades respiratorias
BRSV
BPIV3
BoHV-1
BVDV
Bovine respiratory disease
Respiratory disease of calves
Respiratory diseases
BRSV
BPIV3
BoHV-1
BVDV
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional
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| dc.title.spa.fl_str_mv |
Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros |
| dc.title.translated.eng.fl_str_mv |
Detection of viruses associated with respiratory disease in calves from dairy herds |
| title |
Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros |
| spellingShingle |
Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros 630 - Agricultura y tecnologías relacionadas::636 - Producción animal Enfermedades de los animales Rebaño de leche Enfermedades respiratorias animal diseases dairy herds respiratory diseases Enfermedad respiratoria bovina Enfermedad respiratoria de los terneros Enfermedades respiratorias BRSV BPIV3 BoHV-1 BVDV Bovine respiratory disease Respiratory disease of calves Respiratory diseases BRSV BPIV3 BoHV-1 BVDV |
| title_short |
Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros |
| title_full |
Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros |
| title_fullStr |
Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros |
| title_full_unstemmed |
Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros |
| title_sort |
Detección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecheros |
| dc.creator.fl_str_mv |
Carrillo Torres, Adriana Carolina |
| dc.contributor.advisor.spa.fl_str_mv |
Jairo Aureliano, Jaime Correa |
| dc.contributor.author.spa.fl_str_mv |
Carrillo Torres, Adriana Carolina |
| dc.contributor.researchgroup.spa.fl_str_mv |
Centro de Investigación en Infectología e Inmunología Veterinaria (Ci3V) |
| dc.subject.ddc.spa.fl_str_mv |
630 - Agricultura y tecnologías relacionadas::636 - Producción animal |
| topic |
630 - Agricultura y tecnologías relacionadas::636 - Producción animal Enfermedades de los animales Rebaño de leche Enfermedades respiratorias animal diseases dairy herds respiratory diseases Enfermedad respiratoria bovina Enfermedad respiratoria de los terneros Enfermedades respiratorias BRSV BPIV3 BoHV-1 BVDV Bovine respiratory disease Respiratory disease of calves Respiratory diseases BRSV BPIV3 BoHV-1 BVDV |
| dc.subject.agrovoc.spa.fl_str_mv |
Enfermedades de los animales Rebaño de leche Enfermedades respiratorias |
| dc.subject.agrovoc.eng.fl_str_mv |
animal diseases dairy herds respiratory diseases |
| dc.subject.proposal.spa.fl_str_mv |
Enfermedad respiratoria bovina Enfermedad respiratoria de los terneros Enfermedades respiratorias BRSV BPIV3 BoHV-1 BVDV |
| dc.subject.proposal.eng.fl_str_mv |
Bovine respiratory disease Respiratory disease of calves Respiratory diseases BRSV BPIV3 BoHV-1 BVDV |
| description |
ilustraciones, diagramas, fotografías |
| publishDate |
2023 |
| dc.date.issued.none.fl_str_mv |
2023-10-01 |
| dc.date.accessioned.none.fl_str_mv |
2024-04-09T18:49:57Z |
| dc.date.available.none.fl_str_mv |
2024-04-09T18:49:57Z |
| dc.type.spa.fl_str_mv |
Trabajo de grado - Maestría |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/masterThesis |
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info:eu-repo/semantics/acceptedVersion |
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Text |
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http://purl.org/redcol/resource_type/TM |
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acceptedVersion |
| dc.identifier.uri.none.fl_str_mv |
https://repositorio.unal.edu.co/handle/unal/85886 |
| dc.identifier.instname.spa.fl_str_mv |
Universidad Nacional de Colombia |
| dc.identifier.reponame.spa.fl_str_mv |
Repositorio Institucional Universidad Nacional de Colombia |
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https://repositorio.unal.edu.co/ |
| url |
https://repositorio.unal.edu.co/handle/unal/85886 https://repositorio.unal.edu.co/ |
| identifier_str_mv |
Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia |
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spa |
| language |
spa |
| dc.relation.indexed.spa.fl_str_mv |
Agrosavia Agrovoc |
| dc.relation.references.spa.fl_str_mv |
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The bovine parainfluenza virus type-3 (BPIV-3) hemagglutinin/neuraminidase glycoprotein expressed in baculovirus protects calves against experimental BPIV-3 challenge. Vaccine. 1997;15(6-7):730-738. doi:10.1016/S0264-410X(96)00231-9 Swift BL, Trueblood MS. The present status of the role of the Parainfluenza-3 (PI-3) virus in fetal disease of cattle and sheep. Theriogenology. 1974;2(4):101-107. doi:10.1016/0093-691X(74)90004-1 Lamb RA, Paterson RG, Jardetzky TS. Paramyxovirus membrane fusion: Lessons from the F and HN atomic structures. Virology. 2006;344(1):30-37. doi:10.1016/j.virol.2005.09.007 Ellis JA. Bovine Parainfluenza-3 Virus. Veterinary Clinics of North America: Food Animal Practice. 2010;26(3):575-593. doi:10.1016/j.cvfa.2010.08.002 Bryson DG, McNulty MS, Ball HJ, Neill SD, Connor TJ, Cush PF. The experimental production of pneumonia in calves by intranasal inoculation of parainfluenza type III virus. Vet Rec. 1979;105(25-26):566-573. Ogunbiyi PO, Black WD, Eyre P. 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Veterinary Medicine International. 2022;2022:e7436651. doi:10.1155/2022/7436651 Ortiz-González AD, Buitrago HAL, Bulla-Castañeda DM, et al. Seroprevalence and risk factors associated with bovine herpesvirus 1 in dairy herds of Colombia. Vet World. 2022;15(6):1550-1556. doi:10.14202/vetworld.2022.1550-1556 Flórez LMM, Echeverry OAC, Ordóñez FJP. Estudio seroepidemiológico del Herpesvirus Bovino 1 (BoHV-1) en ganado destinado al sacrificio en la región del Magdalena Medio colombiano. Revista Veterinaria y Zootecnia (On Line). 2011;5(2):82-87. Betancur H C, González T M, Reza G. L. Seroepidemiología de la Rinotraqueitis Infecciosa Bovina en el municipio de Montería, Colombia. Revista MVZ Córdoba. 2006;11(2):830-836. Accessed July 3, 2023. http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0122-02682006000200008&lng=en&nrm=iso&tlng=es Piedrahita LE, Montoya LM, Pedraza FJ. Herpes Virus Bovino tipo 1 (BoHV-1) como posible causa de encefalitis en bovinos de la región del Magdalena Medio Colombiano: Estudio serológico y análisis epidemiológico. Revista Colombiana de Ciencias Pecuarias. 2010;23(2):191-198. Accessed July 3, 2023. http://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0120-06902010000200008&lng=en&nrm=iso&tlng=es Aytogu G, Toker EB, Kadiroglu B, Ates O, Goktuna PT. First Isolation And Characterization Of Bovine Herpesvirus 1.2b (BoHV-1.2b ) Strain From Upper Respiratory Tract Of Cattle In Türkiye. Published online 2022. Cooper VL, Brodersen BW. Respiratory Disease Diagnostics of Cattle. Veterinary Clinics of North America: Food Animal Practice. 2010;26(2):409-416. doi:10.1016/j.cvfa.2010.04.009 Angen Ø, Thomsen J, Larsen LE, et al. Respiratory disease in calves: Microbiological investigations on trans-tracheally aspirated bronchoalveolar fluid and acute phase protein response. Veterinary Microbiology. 2009;137(1-2):165-171. doi:10.1016/j.vetmic.2008.12.024 Godinho KS, Sarasola P, Renoult E, et al. Use of deep nasopharyngeal swabs as a predictive diagnostic method for natural respiratory infections in calves. Vet Rec. 2007;160(1):22-25. doi:10.1136/vr.160.1.22 Caswell JL, Hewson J, Slavić Ð, DeLay J, Bateman K. Laboratory and Postmortem Diagnosis of Bovine Respiratory Disease. Veterinary Clinics of North America: Food Animal Practice. 2012;28(3):419-441. doi:10.1016/j.cvfa.2012.07.004 Powell JG, Richeson JT, Kegley EB, et al. Immunologic, health, and growth responses of beef calves administered pentavalent modified-live virus respiratory vaccine in the presence of maternal antibody versus a traditional vaccination regimen | The Bovine Practitioner. Published online December 18, 2019. Accessed July 5, 2023. https://bovine-ojs-tamu.tdl.org/bovine/article/view/2807 Zhang M, Hill JE, Godson DL, Ngeleka M, Fernando C, Huang Y. The pulmonary virome, bacteriological and histopathological findings in bovine respiratory disease from western Canada. Transbound Emerg Dis. 2020;67(2):924-934. doi:10.1111/tbed.13419 195. Caswell JL, Williams KJ. Respiratory system. In: Jubb, Kennedy & Palmer’s Pathology of Domestic Animals: Volume 2. Elsevier; 2016:465-591.e4. doi:10.1016/B978-0-7020-5318-4.00011-5 Theurer ME, Larson RL, White BJ. Systematic review and meta-analysis of the effectiveness of commercially available vaccines against bovine herpesvirus, bovine viral diarrhea virus, bovine respiratory syncytial virus, and parainfluenza type 3 virus for mitigation of bovine respiratory disease complex in cattle. J Am Vet Med Assoc. 2015;246(1):126-142. doi:10.2460/javma.246.1.126 Kleiboeker SB, Lee SM, Jones CA, Estes DM. Evaluation of shedding of bovine herpesvirus 1, bovine viral diarrhea virus 1, and bovine viral diarrhea virus 2 after vaccination of calves with a multivalent modified-live virus vaccine. Journal of the American Veterinary Medical Association. 2003;222(10):1399-1403. doi:10.2460/javma.2003.222.1399 Chamorro MF, Palomares RA. Bovine Respiratory Disease Vaccination Against Viral Pathogens. Veterinary Clinics of North America: Food Animal Practice. 2020;36(2):461-472. doi:10.1016/j.cvfa.2020.03.006 Van Oirschot JT. Diva vaccines that reduce virus transmission. Journal of Biotechnology. 1999;73(2-3):195-205. doi:10.1016/S0168-1656(99)00121-2 Svensson C, Hultgren J, Oltenacu PA. Morbidity in 3–7-month-old dairy calves in south-western Sweden, and risk factors for diarrhoea and respiratory disease. Preventive Veterinary Medicine. 2006;74(2):162-179. doi:10.1016/j.prevetmed.2005.11.008 Svensson C, Hultgren J, Oltenacu PA. Morbidity in 3–7-month-old dairy calves in south-western Sweden, and risk factors for diarrhoea and respiratory disease. Preventive Veterinary Medicine. 2006;74(2):162-179. doi:10.1016/j.prevetmed.2005.11.008 Hoppe IBAL, Medeiros ASR de, Arns CW, Samara SI. Bovine respiratory syncytial virus seroprevalence and risk factors in non-vaccinated dairy cattle herds in Brazil. BMC Vet Res. 2018;14(1):208. doi:10.1186/s12917-018-1535-8 Roche Diagnostics GmbH RAS. High Pure Viral Nucleic Acid Kit. High Pure Viral Nucleic Acid Kit Rapidly isolate highly purified viral DNA and RNA. https://lifescience.roche.com/documents/High-Pure-Viral-Nucleic-Acid-Kit.pdf Roche Diagnostics GmbH RAS. High Pure Viral Nucleic Acid Kit. High Pure Viral Nucleic Acid Kit Rapidly isolate highly purified viral DNA and RNA. https://lifescience.roche.com/documents/High-Pure-Viral-Nucleic-Acid-Kit.pdf High-Capacity RNA-to-cDNATM Kit. Accessed March 28, 2023. https://www.thermofisher.com/order/catalog/product/4387406 Zhang M, Hill JE, Godson DL, Ngeleka M, Fernando C, Huang Y. The pulmonary virome, bacteriological and histopathological findings in bovine respiratory disease from western Canada. 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Virus Res. 2017;235:77-81. doi:10.1016/j.virusres.2017.04.009 Mars MH, Bruschke CJ, van Oirschot JT. Airborne transmission of BHV1, BRSV, and BVDV among cattle is possible under experimental conditions. Vet Microbiol. 1999;66(3):197-207. doi:10.1016/s0378-1135(99)00009-7 Fulton RW, Briggs RE, Payton ME, et al. Maternally derived humoral immunity to bovine viral diarrhea virus (BVDV) 1a, BVDV1b, BVDV2, bovine herpesvirus-1, parainfluenza-3 virus bovine respiratory syncytial virus, Mannheimia haemolytica and Pasteurella multocida in beef calves, antibody decline by half-life studies and effect on response to vaccination. Vaccine. 2004;22(5-6):643-649. doi:10.1016/j.vaccine.2003.08.033 Platt R, Widel PW, Kesl LD, Roth JA. Comparison of humoral and cellular immune responses to a pentavalent modified live virus vaccine in three age groups of calves with maternal antibodies, before and after BVDV type 2 challenge. 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Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Jairo Aureliano, Jaime Correa4d694f4cf47ac31919e085dd4163b459Carrillo Torres, Adriana Carolina6cd87aaa6086a4962740d141e39be388Centro de Investigación en Infectología e Inmunología Veterinaria (Ci3V)2024-04-09T18:49:57Z2024-04-09T18:49:57Z2023-10-01https://repositorio.unal.edu.co/handle/unal/85886Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramas, fotografíasLa enfermedad respiratoria bovina (ERB) provoca una considerable morbilidad y mortalidad en terneros, resultando en pérdidas económicas significativas. La ERB se caracteriza por ser un complejo donde hay interacciones entre factores medioambientales, el estado inmunológico del huésped y la presencia de agentes virales y/o bacterianos. Los agentes virales primarios asociados a ERB son el herpesvirus bovino 1 (BoHV-1), virus de la diarrea viral bovina (BVDV-1), virus de la parainfluenza bovina (BPIV3) y el virus sincitial respiratorio bovino (BRSV). Este proyecto planteó como objetivo principal la detección mediante RT-PCR / qPCR de los principales virus asociados a ERB (BRSV, BPIV3, BoHV-1 y BVDV). Para lo anterior, se colectaron muestras de tejido pulmonar (P) y raspado nasal (RN) de terneros menores a seis meses de edad provenientes de hatos lecheros, colectadas en planta de beneficio. Los resultados revelaron una tasa de positividad del 25% para BRSV en las muestras de raspado nasal (RN) por PCR. Por su parte, en el caso de BPIV3, se observó una positividad del 14,6% mediante PCR y un aumento significativo al 41,7% mediante qPCR en las muestras de RN. Al analizar las muestras de pulmón, se constató que la positividad fue del 4% mediante PCR y del 26% mediante qPCR para BPIV3. Además, se logró secuenciar el gen P del BPIV3, determinando que la cepa colombiana corresponde al genotipo A. En la evaluación histopatológica, se identificó la neumonía intersticial como el diagnóstico más común. Este estudio representa el primer reporte de BRSV y BPIV3 en Colombia, lo que lo convierte en una contribución pionera en el ámbito académico. (Texto tomado de la fuente),Bovine respiratory disease (BRD) causes considerable morbidity and mortality in calves, resulting in significant economic losses, characterized by a complex interaction between environmental factors, host immune status and the presence of viral and/or bacterial agents. The primary viral agents associated with BRD are bovine herpesvirus 1 (BoHV-1), bovine viral diarrhea virus (BVDV-1), bovine parainfluenza virus (BPIV3) and bovine respiratory syncytial virus (BRSV). The main objective of this project was the detection by RT-PCR/qPCR of the main viruses associated with BSE (BRSV, BPIV3, BoHV-1 and BVDV). For this purpose, samples of lung tissue (P) and nasal scraping (RN) were collected from calves under six months of age from dairy herds, collected at the processing plant. The results revealed a 25% positivity rate for BRSV in nasal scraping (NR) samples by PCR. For BPIV3, a positivity of 14.6% was observed by PCR and a significant increase to 41.7% by qPCR in NR samples. When lung samples were analyzed, positivity was found to be 4% by PCR and 26% by qPCR for BPIV3. In addition, the P gene of BPIV3 was sequenced and it was determined that the Colombian strain corresponds to genotype A. Histopathological evaluation identified interstitial pneumonia as the most common diagnosis. This study represents the first report of BRSV and BPIV3 in Colombia, which makes it a pioneering contribution in the academic field.MaestríaMagíster en Salud Animal o Magíster en Producción AnimalMicrobiología e inmunologíaxvi, 80 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina Veterinaria y de Zootecnia - Maestría en Salud y Producción AnimalFacultad de Medicina Veterinaria y de ZootecniaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá630 - Agricultura y tecnologías relacionadas::636 - Producción animalEnfermedades de los animalesRebaño de lecheEnfermedades respiratoriasanimal diseasesdairy herdsrespiratory diseasesEnfermedad respiratoria bovinaEnfermedad respiratoria de los ternerosEnfermedades respiratoriasBRSVBPIV3BoHV-1BVDVBovine respiratory diseaseRespiratory disease of calvesRespiratory diseasesBRSVBPIV3BoHV-1BVDVDetección de virus asociados con enfermedad respiratoria en terneros provenientes de hatos lecherosDetection of viruses associated with respiratory disease in calves from dairy herdsTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/acceptedVersionTexthttp://purl.org/redcol/resource_type/TMAgrosaviaAgrovocZhu YM, Shi HF, Gao YR, et al. Isolation and genetic characterization of bovine parainfluenza virus type 3 from cattle in China. Veterinary Microbiology. 2011;149(3):446-451. doi:10.1016/j.vetmic.2010.11.011Bryson DG, McFerran JB, Ball HJ, Neill SD. Observations on outbreaks of respiratory disease in housed calves--(1) Epidemiological, clinical and microbiological findings. Vet Rec. 1978;103(22):485-489. doi:10.1136/vr.103.22.485Ellis JA. Update on viral pathogenesis in BRD. Anim Health Res Rev. 2009;10(2):149-153. doi:10.1017/S146625230999020XHay KE, Ambrose RCK, Morton JM, et al. Effects of exposure to Bovine viral diarrhoea virus 1 on risk of bovine respiratory disease in Australian feedlot cattle. Preventive Veterinary Medicine. 2016;126:159-169. doi:10.1016/j.prevetmed.2016.01.025Murray GM, O’Neill RG, Lee AM, et al. The bovine paranasal sinuses: Bacterial flora, epithelial expression of nitric oxide and potential role in the in-herd persistence of respiratory disease pathogens. Melcher U, ed. PLoS ONE. 2017;12(3):e0173845. doi:10.1371/journal.pone.0173845Horwood PF, Mahony TJ. Multiplex real-time RT-PCR detection of three viruses associated with the bovine respiratory disease complex. Journal of Virological Methods. 2011;171(2):360-363. doi:10.1016/j.jviromet.2010.11.020Blakebrough-Hall C, McMeniman JP, González LA. An evaluation of the economic effects of bovine respiratory disease on animal performance, carcass traits, and economic outcomes in feedlot cattle defined using four BRD diagnosis methods. J Anim Sci. 2020;98(2):skaa005. doi:10.1093/jas/skaa005Gorden PJ, Plummer P. Control, Management, and Prevention of Bovine Respiratory Disease in Dairy Calves and Cows. Veterinary Clinics of North America: Food Animal Practice. 2010;26(2):243-259. doi:10.1016/j.cvfa.2010.03.004Bolaños D, Donado P, Oliver Espinosa OJ. The Effect Of Management Factors On Morbidity And Mortality Calves Up To Two Months Of Age In Colombian Dairy Farms At high Altitudes. In: Vol XIX. ; 1996.Escobar Vargas A, Bonilla Quintero R, Oliver Espinosa O, Donado P. Factores de Manejo Que Afectan La Morbilidad y Mortalidad En Terneros Durante Sus Primeros Tres Meses de Vida En El Municipio de San Pedro de Los Milagros, Departamento de Antioquia. 1997.Mejía Ortega G, Oliver Espinosa OJ. Estudio Sobre Los Factores Que Afectan La Morbilidad y La Mortalidad de Terneros Durante Sus Primeros Cuatro Meses de Edad En Hatos Selectos de La Sabana de Bogotá. 2005.Veit HP, Farrell RL. The anatomy and physiology of the bovine respiratory system relating to pulmonary disease. Cornell Vet. 1978;68(4):555-581.Mariassy AT, Plopper CG, Dungworth DL. Characteristics of bovine lung as observed by scanning electron microscopy. Anat Rec. 1975;183(1):13-26. doi:10.1002/ar.1091830103Cooper VL, Brodersen BW. Respiratory Disease Diagnostics of Cattle. 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Viruses. 2022;14(10):2221. doi:10.3390/v14102221InvestigadoresLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/85886/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINAL1072426362.2023.pdf1072426362.2023.pdfTesis de Maestría en Salud y Producción Animalapplication/pdf7361714https://repositorio.unal.edu.co/bitstream/unal/85886/2/1072426362.2023.pdf15ef3cf776d8cc58d3aff650d6c81877MD52THUMBNAIL1072426362.2023.pdf.jpg1072426362.2023.pdf.jpgGenerated Thumbnailimage/jpeg5162https://repositorio.unal.edu.co/bitstream/unal/85886/3/1072426362.2023.pdf.jpg7c1d04b329f6da126a1698f5548c74d4MD53unal/85886oai:repositorio.unal.edu.co:unal/858862024-08-23 23:12:11.71Repositorio Institucional Universidad Nacional de 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