Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro

ilustraciones, diagramas

Autores:: Bernal Quintero, Laura Angelica

Tipo de recurso:

Fecha de publicación:: 2023

Institución:: Universidad Nacional de Colombia

Repositorio:: Universidad Nacional de Colombia

Idioma:: spa

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repository_id_str
dc.title.spa.fl_str_mv	Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro
dc.title.translated.eng.fl_str_mv	Evaluation of the factors that influence the pregnancy rate and embryo survival in recipients of bovine embryos produced in-vitro
title	Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro
spellingShingle	Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro 630 - Agricultura y tecnologías relacionadas::636 - Producción animal Bovinos Embrión de mamífero Bovinos Embryo, Mammalian Embriones bovinos Embriones in-vitro Tasa de preñez Enfermedades infecciosas reproductivas Bovine embryos In-vitro embryos Pregnancy rate Reproductive infectious diseases
title_short	Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro
title_full	Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro
title_fullStr	Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro
title_full_unstemmed	Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro
title_sort	Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro
dc.creator.fl_str_mv	Bernal Quintero, Laura Angelica
dc.contributor.advisor.none.fl_str_mv	Zambrano Varón, Jorge Luis Jiménes Escobar, Claudia
dc.contributor.author.none.fl_str_mv	Bernal Quintero, Laura Angelica
dc.contributor.researchgroup.spa.fl_str_mv	Reproducción Animal y Salud de Hato
dc.subject.ddc.spa.fl_str_mv	630 - Agricultura y tecnologías relacionadas::636 - Producción animal
topic	630 - Agricultura y tecnologías relacionadas::636 - Producción animal Bovinos Embrión de mamífero Bovinos Embryo, Mammalian Embriones bovinos Embriones in-vitro Tasa de preñez Enfermedades infecciosas reproductivas Bovine embryos In-vitro embryos Pregnancy rate Reproductive infectious diseases
dc.subject.armarc.spa.fl_str_mv	Bovinos
dc.subject.decs.spa.fl_str_mv	Embrión de mamífero Bovinos
dc.subject.decs.eng.fl_str_mv	Embryo, Mammalian
dc.subject.proposal.spa.fl_str_mv	Embriones bovinos Embriones in-vitro Tasa de preñez Enfermedades infecciosas reproductivas
dc.subject.proposal.eng.fl_str_mv	Bovine embryos In-vitro embryos Pregnancy rate Reproductive infectious diseases
description	ilustraciones, diagramas
publishDate	2023
dc.date.accessioned.none.fl_str_mv	2023-10-06T22:19:35Z
dc.date.available.none.fl_str_mv	2023-10-06T22:19:35Z
dc.date.issued.none.fl_str_mv	2023
dc.type.spa.fl_str_mv	Trabajo de grado - Maestría
dc.type.driver.spa.fl_str_mv	info:eu-repo/semantics/masterThesis
dc.type.coarversion.spa.fl_str_mv	http://purl.org/coar/version/c_dc82b40f9837b551
dc.type.content.spa.fl_str_mv	Text
dc.type.redcol.spa.fl_str_mv	http://purl.org/redcol/resource_type/TM
dc.identifier.uri.none.fl_str_mv	https://repositorio.unal.edu.co/handle/unal/84783
dc.identifier.instname.spa.fl_str_mv	Universidad Nacional de Colombia
dc.identifier.reponame.spa.fl_str_mv	Repositorio Institucional Universidad Nacional de Colombia
dc.identifier.repourl.spa.fl_str_mv	https://repositorio.unal.edu.co/
url	https://repositorio.unal.edu.co/handle/unal/84783 https://repositorio.unal.edu.co/
identifier_str_mv	Universidad Nacional de Colombia Repositorio Institucional Universidad Nacional de Colombia
dc.language.iso.spa.fl_str_mv	spa
language	spa
dc.relation.references.spa.fl_str_mv	Bonilla León, L., Mejía Gallego, A., Gómez Domínguez, R., Torres Londoño, M., & Uribe García, F. (2018). Viabilidad y tasa de preñez de embriones producidos in vitro a partir de semen sexado comparado con semen convencional en Bos taurus y Bos indicus. Revista de Investigaciones Veterinarias Del Perú, 29(4), 1377. https://doi.org/10.15381/rivep.v29i4.14297 Chebel, R. C., Demetrio, D. G. B., & Metzger, J. (2008). Factors affecting success of embryo collection and transfer in large dairy herds. Theriogenology, 69, 98–106. https://doi.org/10.1016/j.theriogenology.2007.09.008 Diniz, J. V, Ochoa, J. C., Montoya, L. M., Satrapa, R., Okuda, L. H., Pituco, E. M., … Oba, E. (2016). Immune-serological identification of infectious agents with influence on bovine embryo transfer in the north of Brazil TT - Identificación inmunoserológica de agentes infecciosos con influencia sobre la transferencia de embriones en el norte de Brasil. Archivos de Medicina Veterinaria, 48(2), 145–152. Retrieved from http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2016000200003&lang=pt Farfan Rojas, O. O., & Porras Vargas, J. L. (2013). Evaluacion de la tasa de concepcion de tres razas bovinas receptoras de embriones en el Tropico Alto. Ciencia y Agricultura Vol., 11, 77–83. Naranjo Guerrero, L. F., Rodríguez Colorado, N., & Mejía Araque, J. (2022). Prevalencia de diarrea viral bovina, neosporosis bovina, leucosis bovina enzoótica y paratuberculosis bovina en vacas de doble propósito en condiciones del trópico colombiano. Revista de Investigaciones Veterinarias Del Perú, 33(2), e20694. https://doi.org/10.15381/rivep.v33i2.20694 Oyuela, L. A., & Jimenez, C. (2010). Factores que afectan la tasa de preñez en programas de transferencia de embriones. Revista de La Facultad de Medicina Veterinaria y de Zootecnia, 191–200. Oyuela, Lino Andres. (2009). FACTORES QUE AFECTAN LA TASA DE PREÑEZ EN PROGRAMAS DE TRANSFERENCIA DE EMBRIONES PRODUCIDOS IN-VITRO, EN RAZAS CEBUINAS LINO. Retrieved from http://www.bvs.hn/cu-2007/ponencias/SLD/SLD101.pdf Roper, D. A., Schrick, F. N., Edwards, J. L., Hopkins, F. M., Prado, T. M., Wilkerson, J. B., … Smith, W. B. (2018). Factors in cattle a ffecting embryo transfer pregnancies in recipient animals. Animal Reproduction Science, 199(November), 79–83. https://doi.org/10.1016/j.anireprosci.2018.11.001 Alkan, H., Karaşahin, T., Dursun, Ş., Satılmış, F., Erdem, H., & Güler, M. (2020). Evaluation of the factors that affect the pregnancy rates during embryo transfer in beef heifers. Reproduction in Domestic Animals, 55(4), 421–428. https://doi.org/10.1111/rda.13623 Binelli, M., Thatcher, W. W., Mattos, R., & Baruselli, P. S. (2001). Antiluteolytic strategies to improve fertility in cattle. Theriogenology, 56(9), 1451–1463. https://doi.org/10.1016/S0093-691X(01)00646-X Cordeiro, A. L. L., Satrapa, R. A., Gregianini, H. A. G., Gregianini, J. T. F., Maia, G. F. N., & Landim-Alvarenga, F. C. (2020). Influence of temperature-humidity index on conception rate of Nelore embryos produced in vitro in northern Brazil. Tropical Animal Health and Production, 52(3), 1527–1532. https://doi.org/10.1007/s11250-019-02141-4 de Oliveira, V. S. F., Álvarez-Garcia, G., Ortega-Mora, L. M., Borges, L. M. F., & da Silva, A. C. (2010). Abortions in bovines and Neospora caninum transmission in an embryo transfer center. Veterinary Parasitology, 173(3–4), 206–210. https://doi.org/10.1016/j.vetpar.2010.06.028 Ferraz, P. A., Burnley, C., Karanja, J., Viera-neto, A., Santos, J. E. P., Chebel, R. C., & Galvão, K. N. (2016). Factors affecting the success of a large embryo transfer program in Holstein cattle in a commercial herd in the southeast region of the United States. Theriogenology, 86(7), 1834–1841. https://doi.org/10.1016/j.theriogenology.2016.05.032 Guerra, A., & Álvaro. (2004). Pubertad en la hembra bovina. Sitio Argentino de Producción Animal, 1–7. Retrieved from http://www.produccion-animal.com.ar/informacion_tecnica/cria/57-pubertad_en_la_hembra_bovina.pdf Hansen, P. J. (2007). Exploitation of genetic and physiological determinants of embryonic resistance to elevated temperature to improve embryonic survival in dairy cattle during heat stress. 242–249. https://doi.org/10.1016/j.theriogenology.2007.04.008 Holguín, G., Montaña, D., & Valbuena, D. (2013). Corpus luteum diameter and embryo developmental stage are associated with pregnancy rate : data analysis from 17 , 521 embryo transfers from a commercial in vitro bovine embryo production program. Anim. Reprod., 10(2), 106–111. Julon, D., Burga, N., Bardales, W., & Puicón, V. (2018). Factors affecting the pregnancy rate in transfers of embryos in crossbreed Brown Swiss. MOJ Anatomy & Physiology, 5(2), 101–104. https://doi.org/10.15406/mojap.2018.05.00171 Mann, G. E., Lamming, G. E., Robinson, R. S., & Wathes, D. C. (1999). The regulation of interferon-tau production and uterine hormone receptors during early pregnancy. Journal of Reproduction and Fertility. Supplement, 54, 317–328. Marzouk, A., Genedy, T., Abdel-Razek, E., Zaghloul, A., & Elbaz, H. (2020). Factors Affecting Pregnancy Rate Per Embryo Transfer of In Vivo Produced Embryos in Recipient Holstein Heifers. Journal of Current Veterinary Research, 1, 1–10. Nardone, A., Ronchi, B., Lacetera, N., Ranieri, M. S., & Bernabucci, U. (2010). Effects of climate changes on animal production and sustainability of livestock systems ☆. Livestock Science, 130(1–3), 57–69. https://doi.org/10.1016/j.livsci.2010.02.011 Negrón-Pérez, V. M., Fausnacht, D. W., & Rhoads, M. L. (2019). Invited review: Management strategies capable of improving the reproductive performance of heat-stressed dairy cattle. Journal of Dairy Science, 102(12), 10695–10710. https://doi.org/10.3168/jds.2019-16718 Nogueira, É., Cardoso, G. S., Romero, H., Junior, M., Dias, M., Carlos, L., … Borges, J. C. (2012). Effect of breed and corpus luteum on pregnancy rate of bovine embryo recipients. Revista Brasileira de Zootecnia, 41(2001), 2129–2133. Occhio, M. J. D., Baruselli, P. S., & Campanile, G. (2018). Influence of nutrition, body condition, and metabolic status on reproduction in female beef cattle: A review. Theriogenology. https://doi.org/10.1016/j.theriogenology.2018.11.010 Ongubo, M. N., Rachuonyo, H. A., Lusweti, F. N., Kios, D. K., Kitilit, J. K., Musee, K., … Corporation, A. D. (2015). Factors affecting conception rates in cattle following embryo transfer. Uganda Journal of Agricultural Sciences, 16(1), 19–27. Perez Durand, M. G., Bejar Huaylla, T., Quispe Barriga, Y. M., Fernadez Ruelas, E. P., Flores Guillen, M. A., Delgado Castro, A., & Perez Guerra, U. H. (2022). Factores que afectan la tasa de preñez en receptoras de embriones producidos in vitro bajo condiciones de altura. Revista de Investigaciones Veterinarias Del Perú, 33(3), 1–10. Sanhueza, J. M., Heuer, C., & West, D. (2013). Contribution of Leptospira, Neospora caninum and bovine viral diarrhea virus to fetal loss of beef cattle in New Zealand. Preventive Veterinary Medicine, 112(1–2), 90–98. https://doi.org/10.1016/j.prevetmed.2013.07.009 Santos, J. E. P., Rutigliano, H. M., & Sà Filho, M. F. (2009). Risk factors for resumption of postpartum estrous cycles and embryonic survival in lactating dairy cows. Animal Reproduction, 110, 207–221. https://doi.org/10.1016/j.anireprosci.2008.01.014 Sartori, R., Sartor-Bergfelt, R., Mertens, S. A., Guenther, J. N., Parrish, J. J., & Wiltbank, M. C. (2010). Fertilization and Early Embryonic Development in Heifers and Lactating Cows in Summer and Lactating and Dry Cows in Winter. Journal of Dairy Science, 85(11), 2803–2812. https://doi.org/10.3168/jds.s0022-0302(02)74367-1 Scenna, F. N., Hockett, M. E., Towns, T. M., Saxton, A. M., Rohrbach, N. R., Wehrman, M. E., & Schrick, F. N. (2005). Influence of a prostaglandin synthesis inhibitor administered at embryo transfer on pregnancy rates of recipient cows. 78, 38–45. https://doi.org/10.1016/j.prostaglandins.2005.02.003 Siqueira, L. G. B., Torres, C. A. A., Souza, E. D., Monteiro Jr., P. L. J., Arashiro, E. K. ., Camargo, L. S. A., … Viana, J. H. M. (2009). Pregnancy rates and corpus luteum – related factors affecting pregnancy establishment in bovine recipients synchronized for fixed-time embryo transfer. Theriogenology, 72, 949–958. https://doi.org/10.1016/j.theriogenology.2009.06.013 Vandaele, L. (2010). INTRINSIC FACTORS AFFECTING APOPTOSIS IN BOVINE IN VITRO PRODUCED EMBRYOS. In Universiteit Gent. https://doi.org/10.1016/j.theriogenology.2015.10.036 Vasquez Ch., Y., & Amilcar Bò., G. (2017). Evaluacion De Los Diferentes Factores Que Afectan La Reproduccion Bovina Con Relacion a Bienestar Animal (Instituto de Reproduccion Animal Cordoba IRAC). Retrieved from https://rdu.unc.edu.ar/bitstream/handle/11086/4859/ Yoo, H. S. (2010). Infectious Causes of Reproductive Disorders in Cattle. Journal of Reproduction and Development, 56, 53–60. Viana, J., IETS Data Retrieval Committee in Embryo Technology Newsletter. 2021, International Embryo & Technology Society. Alkan, H., et al., Evaluation of the factors that affect the pregnancy rates during embryo transfer in beef heifers. Reprod Domest Anim, 2020. 55(4): p. 421-428. Pontes, J.H.F., et al., Ovum pick up, in vitro embryo production, and pregnancy rates from a large-scale commercial program using Nelore cattle (Bos indicus) donors. Theriogenology, 2011. 75(9): p. 1640-1646. Looney, C.R., et al., Improving fertility in beef cow recipients. Theriogenology, 2006. 65(1): p. 201-9 D'Occhio, M.J., P.S. Baruselli, and G. Campanile, Influence of nutrition, body condition, and metabolic status on reproduction in female beef cattle: A review. Theriogenology, 2019. 125: p. 277-284. Mann, G.E., et al., The regulation of interferon-tau production and uterine hormone receptors during early pregnancy. J Reprod Fertil Suppl, 1999. 54: p. 317-28. Binelli, M., et al., Antiluteolytic strategies to improve fertility in cattle. Theriogenology, 2001. 56(9): p. 1451-1463. Roper, D.A., et al., Factors in cattle affecting embryo transfer pregnancies in recipient animals. Anim Reprod Sci, 2018. 199: p. 79-83. Chebel, R.C., D.G. Demétrio, and J. Metzger, Factors affecting the success of embryo collection and transfer in large dairy herds. Theriogenology, 2008. 69(1): p. 98-106. Sánchez, J.M., et al., Embryonic maternal interaction in cattle and its relationship with fertility. Reprod Domest Anim, 2018. 53 Suppl 2: p. 20-27. Givens, D.M. and M.S.D. Marley, Infectious causes of embryonic and fetal mortality. Theriogenology, 2008. 70(3): p. 270-285. Forar, A.L., et al., Fetal loss frequency in ten Holstein dairy herds. Theriogenology, 1996. 45(8): p. 1505-1513. Kendall, P.E. and J.R. Webster, Season and physiological status affects the circadian body temperature rhythm of dairy cows. Livestock Science, 2009. 125(2): p. 155-160. Lemeshow, S. and D.W. Hosmer, JR., A Review of Goddess of fit Statistics for use in the development of Logistic Regression Models American Journal of Epidemiology, 1982. 115(1): p. 92-106. Bielanski, A., et al., Transmission of bovine viral diarrhea virus (BVDV) via in vitro-fertilized embryos to recipients, but not to their offspring. Theriogenology, 2009. 71(3): p. 499-508. Baillargeon, P., et al., Evaluation of the embryo transfer procedure proposed by the International Embryo Transfer Society as a method of controlling vertical transmission of Neospora caninum in cattle. J Am Vet Med Assoc, 2001. 218(11): p. 1803-6. Shabbir, M.Z., et al., Seroprevalence of Neospora caninum and Brucella abortus in dairy cattle herds with high abortion rates. J Parasitol, 2011. 97(4): p. 740-2. Walz, P.H., et al., Evaluation of reproductive protection against bovine viral diarrhea virus and bovine herpesvirus-1 afforded by annual revaccination with modified-live viral or combination modified-live/killed viral vaccines after primary vaccination with the modified-live viral vaccine. Vaccine, 2017. 35(7): p. 1046-1054. Pereira, M.H., et al., Effects of vaccination against reproductive diseases on reproductive performance of lactating dairy cows submitted to AI. Anim Reprod Sci, 2013. 137(3-4): p. 156-62. Aono, F.H., et al., Effects of vaccination against reproductive diseases on reproductive performance of beef cows submitted to fixed-timed AI in Brazilian cow-calf operations. Theriogenology, 2013. 79(2): p. 242-8. Edelhoff, I.N.F., et al., Inflammatory diseases in dairy cows: Risk factors and associations with pregnancy after embryo transfer. J Dairy Sci, 2020. 103(12): p. 11970-11987. Banos, G., et al., Identification of immune traits correlated with dairy cow health, reproduction, and productivity. PLoS One, 2013. 8(6): p. e65766. Moraes, J.G.N., et al., Uterine influences on conceptus development in fertility-classified animals. 2018. 115(8): p. E1749-E1758. Sheldon, I.M., et al., Uterine diseases in cattle after parturition. Vet J, 2008. 176(1): p. 115-21. Dahl, M.O., et al., Evidence that mastitis can cause pregnancy loss in dairy cows: A systematic review of observational studies. Journal of Dairy Science, 2017. 100(10): p. 8322-8329. Rodríguez-Lecompte, J.C., et al., Evaluation of the systemic innate immune response and metabolic alterations of nonlactating cows with diet-induced subacute ruminal acidosis. J Dairy Sci, 2014. 97(12): p. 7777-87. Mohammad, S. and C. Thiemermann, Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions. Front Immunol, 2020. 11: p. 594150. Baumgard, L.H. and R.P. Rhoads, Jr., Effects of heat stress on postabsorptive metabolism and energetics. Annu Rev Anim Biosci, 2013. 1: p. 311-37. Schrödl, W., et al., Acute phase proteins as promising biomarkers: Perspectives and limitations for human and veterinary medicine. Proteomics Clin Appl, 2016. 10(11): p. 1077-1092. Edelhoff, I.N.F., et al., Inflammatory diseases in dairy cows: Risk factors and associations with pregnancy after embryo transfer. Journal of Dairy Science, 2020. 103(12): p. 11970-11987. Yasuda, K. and E. Kuroda, Role of eosinophils in protective immunity against secondary nematode infections. Immunological Medicine, 2019. 42(4): p. 148-155. Wiltbank, M., A. Gümen, and R.J.T. Sartori, Physiological classification of anovulatory conditions in cattle. 2002. 57(1): p. 21-52. Walsh, R., et al., Prevalence and risk factors for the postpartum anovulatory condition in dairy cows. 2007. 90(1): p. 315-324. Kadokawa, H., D. Blache, and G.J.J.o.d.s. Martin, Plasma leptin concentrations correlate with luteinizing hormone secretion in early postpartum Holstein cows. 2006. 89(8): p. 3020-3027. Wathes, D.C., et al., Negative energy balance alters global gene expression and immune responses in the uterus of postpartum dairy cows. 2009. 39(1): p. 1-13. Ribeiro, E., et al., Conceptus development and transcriptome at preimplantation stages in lactating dairy cows of distinct genetic groups and estrous cyclic statuses. 2016. 99(6): p. 4761-4777. VanRaden, P.M. and R.H. Miller, Effects of nonadditive genetic interactions, inbreeding, and recessive defects on embryo and fetal loss by seventy days. J Dairy Sci, 2006. 89(7): p. 2716-21. Baruselli, P.S., et al., Use of embryo transfer to alleviate infertility caused by heat stress. Theriogenology, 2020. 155: p. 1-11. Mikkola, M., M. Andersson, and J. Taponen, Transfer of cattle embryos produced with sex-sorted semen results in impaired pregnancy rate and increased male calf mortality. Theriogenology, 2015. 84(7): p. 1118-1122. Pontes, J.H.F., et al., Large-scale in vitro embryo production and pregnancy rates from Bos taurus, Bos indicus, and indicus-Taurus dairy cows using sexed sperm. Theriogenology, 2010. 74(8): p. 1349-1355. Chenoweth, P.J., Influence of the male on embryo quality. Theriogenology, 2007. 68(3): p. 308-15. Zhang, S., et al., The effect of prostaglandin E2 receptor (PTGER2) activation on growth factor expression and cell proliferation in bovine endometrial explants. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2017. 122: p. 16-23. Sakai, S., et al., Heat stress influences the attenuation of prostaglandin synthesis by interferon tau in bovine endometrial cells. Theriogenology, 2021. 165: p. 52-58. Nanas, I., et al., Early embryo losses, progesterone, and pregnancy-associated glycoproteins levels during summer heat stress in dairy cows. Journal of Thermal Biology, 2021. 98: p. 102951. Dorniak, P., F. Bazer, and T.J.J.o.a.s. Spencer, Physiology and Endocrinology Symposium: biological role of interferon tau in endometrial function and conceptus elongation. 2013. 91(4): p. 1627-1638. Kornmatitsuk, B., et al., Different types of postpartum luteal activity affected by the exposure of heat stress and subsequent reproductive performance in Holstein lactating cows. 2008. 43(5): p. 515-519. Pegorer, M.F., et al., Influence of sire and sire breed (Gyr versus Holstein) on the establishment of pregnancy and embryonic loss in lactating Holstein cows during summer heat stress. Theriogenology, 2007. 67(4): p. 692-697. Silke, V., et al., Extent, pattern and factors associated with late embryonic loss in dairy cows. Animal Reproduction Science, 2002. 71(1): p. 1-12. Libonati, H.A., et al., Leptospirosis is strongly associated with estrus repetition on cattle. Trop Anim Health Prod, 2018. 50(7): p. 1625-1629. Givens, M.D., J.A. Gard, and D.A. Stringfellow, Relative risks and approaches to biosecurity in the use of embryo technologies in livestock. Theriogenology, 2007. 68(3): p. 298-307. Chi, J., et al., Management factors related to seroprevalences to the bovine viral diarrhea virus, bovine-leukosis virus, Mycobacterium avium subspecies paratuberculosis, and Neospora caninum in dairy herds in the Canadian Maritimes. Preventive Veterinary Medicine, 2002. 55(1): p. 57-68. De Rensis, F., et al., Causes of declining fertility in dairy cows during the warm season. Theriogenology, 2017. 91: p. 145-153. Gendelman, M. and Z. Roth, In vivo vs. in vitro models for studying the effects of elevated temperature on the GV-stage oocyte, subsequent developmental competence, and gene expression. Anim Reprod Sci, 2012. 134(3-4): p. 125-34. Hansen, P.J., et al., Adverse impact of heat stress on embryo production: causes and strategies for mitigation. Theriogenology, 2001. 55(1): p. 91-103. Abdalla, H., et al., Maternal and non-maternal factors associated with late embryonic and early fetal losses in dairy cows. Theriogenology, 2017. 100: p. 16-23. Diniz, J.V.A., et al., Fertility traits of recipient cows raised in the Amazon biome. Livestock Science, 2020. 240: p. 104147. Cooke, R.F., et al., Effects of acclimation to human interaction on performance, temperament, physiological responses, and pregnancy rates of Brahman-crossbred cows. J Anim Sci, 2009. 87(12): p. 4125-32. Dobson, H., et al., Is stress all that important? Theriogenology, 2001. 55(1): p. 65-73.
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spelling	Atribución-NoComercial-SinDerivadas 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Zambrano Varón, Jorge Luis6ef953d4ee9dbb30d28abf055dccb7ebJiménes Escobar, Claudia59003bd548d5e8d5120e3855c3da1a1dBernal Quintero, Laura Angelica4d494f1ccca9e3a137a71f646c6caba0Reproducción Animal y Salud de Hato2023-10-06T22:19:35Z2023-10-06T22:19:35Z2023https://repositorio.unal.edu.co/handle/unal/84783Universidad Nacional de ColombiaRepositorio Institucional Universidad Nacional de Colombiahttps://repositorio.unal.edu.co/ilustraciones, diagramasLa producción de embriones in vitro (PIV), en los últimos años se ha convertido en una biotecnología reproductiva de importante uso en los sistemas productivos bovinos. Sin embargo, por sus costos, es poco asequible para los pequeños y medianos productores. Aunque existen algunos criterios específicos para la selección de hembras aptas para ser receptoras de embriones, es necesario identificar los factores que pueden afectar negativamente el éxito de los programas masivos de transferencia de embriones PIV. El objetivo de este estudio fue evaluar los factores asociados con la tasa de preñez y la supervivencia embrionaria en receptoras bovinas en un programa de transferencia de embriones producidos in vitro en el Departamento de Cundinamarca. Se realizaron n=4083 transferencias de embriones, en 26 municipios del departamento de Cundinamarca. En las receptoras se evaluaron, factores intrínsecos y extrínsecos que podían influir sobre la probabilidad de preñez. Además, se evaluaron algunos factores medioambientales como temperatura corporal y medioambiental al momento de la trasferencia, y el nivel de exposición a patógenos que afectan la reproducción a través de la realización de pruebas serológicas para: Diarrea Viral Bovina, Herpes Virus Bovino-1 , Brucella abortus, Leucosis Bovina, Neospora caninum, y seis serovares de Leptospira (L. Hardjo prajinto, L. Hardjo bovis, L.pomona, L. canicola, L. grippotyphosa L. Icterohaemorrhagiae). Se tuvieron en cuenta como factores de exclusión, animales persistentemente infectados de DVB (PI-DVB), positivos a B. abortus y a N. caninum. Adicionalmente, se evaluó el estado de salud de las receptoras a través de la realización de pruebas de función hepática, renal, hemograma y de parásitos gastrointestinales y su relación con el resultado del diagnóstico de gestación y la supervivencia embrionaria. Los diagnósticos de gestación y de viabilidad gestacional se realizaron el día 30 y 60 respectivamente, post-transferencia. Los datos fueron analizados con un modelo de regresión logística binaria. La TP promedio del estudio fue del 26,1%. Los factores asociados a la probabilidad de preñez viable fueron la vacunación contra enfermedades reproductivas (OR= 0.4, IC 95% (0.2-0.6), p= 0.001), uso de semen convencional en la FIV de los embriones PIV (OR= 0.6 , IC 95% 0,4-0,9, p = 0,009), la adecuada ciclicidad ovárica de las receptoras al momento de la sincronización del estro (OR=1,2, IC 95% 1. 1 – 1.5, p=0.025), volumen del cuerpo CL al momento de la ET (OR = 1,9, IC del 95 %: 1,0-3,8, p=0,05), temperatura ambiental (OR= 1,6, IC 95% 1,2-2,2 P=0,005), Humedad Relativa (OR = 1.9, IC 95% 1.3-2.7, p = 0.001). La pérdida gestacional del estudio fue de 8.3%, asociada a los factores de exposición a HVB-1(OR= 5,4, IC 95% 1,1-27,6, p = 0,043), L. hardjo bovis y L canicola (OR= 4,0, IC 95% 1,1-14,9, p=0,032) y (OR= 8,9, IC 95% 1,6-14,0, p=0,021), respectivamente, cambios en la condición corporal (OR= 3,6, IC 95% 1,1-12,8, p =0,048), temperatura corporal ( OR = 0,1, IC 95 % 0,007-0,8, p = 0,03) e Índice de Temperatura/Humedad (OR= 0,023, IC 95% 0,001-0,775, p =0,036). Los resultados de esta investigación son importante evidencia para la estructuración de programas de transferencia de embriones, en cuanto a las consideraciones para la selección de receptoras, estatus sanitario de las mismas, factores ambientales, factores intrínsecos/extrínsecos, en pro de la tasa de preñez y la supervivencia embrionaria. (Texto tomado de la fuente)In recent years the in vitro embryos production (PIV), has become into one of the most important reproductive biotechnologies for the bovine reproductive system. Nevertheless, for its cost, it’s not affordable for small and medium producers. Though there are some criteria to select the suitable female for being the embryos receiver, it’s necessary to identify the factors could affect in a negative way the success of PIV embryos transfer massive programs. This study goal was to evaluate the factors associated to the pregnancy rate and embryo survival in bovine receptors in an in vitro produced embryos transfer program in the Department of Cundinamarca. N=4083 embryos transfers were made in 26 municipalities of the department of Cundinamarca. In the receptors was evaluated intrinsic and extrinsic factors that may influence the pregnancy probability. Further some environmental factors were evaluated, like body and environmental temperature at the time of transfer, and the level of exposure to pathogens that affects the reproduction through serological tests to: Bovine Viral Diarrhea, Bovine Herpes Virus-1, Brucella abortus, Bovine Leukosis, Neospora caninum, and six serovars of Leptospira (L. hardjo prajinto, L. hardjo bovis, L. pomona, L. canicola, L. grippotyphosa L. Icterohaemorrhagiae). They were considered as exclusion factors, animals persistently infected with BVD (PI-BVD), positive for B. abortus and N. caninum. Besides the health status of the receptors was evaluated through the liver, kidney function, blood count and gastrointestinal parasites test and their relationship with the result of pregnancy diagnosis and embryonic survival. Pregnancy and gestational viability diagnoses were performed post-transfer on the 30th and 60th day. The data was analyzed with a binary logistic regression model. The average pregnancy rate in the study was 26.1%. The factors associated to the probability of viable pregnancy were vaccination against reproductive diseases (OR= 0.4, IC 95% (0.2-0.6), p= 0.001), use of conventional semen in IVF of the embryos PIV (OR= 0.6, IC 95% 0,4-0,9, p = 0,009), the adequate ovarian cyclicity of the receptors at the time of estrous synchronization (OR=1,2, IC 95% 1. 1 – 1.5, p=0.025), CL body volume at time of ET (OR = 1,9, IC del 95 %: 1,0-3,8, p=0,05), environmental temperature (OR= 1,6, IC 95% 1,2-2,2 P=0,005), relative humidity (OR = 1.9, IC 95% 1.3-2.7, p = 0.001). The study gestational loss was 8.3%, associated with exposure factors to HVB-1 (OR= 5,4, IC 95% 1,1-27,6, p = 0,043), L. hardjo bovis and L. canicola (OR= 4.0, 95% CI 1.1-14.9, p=0.032) and (OR= 8.9, 95% CI 1.6-14.0, p= 0.021), respectively, changes in body condition (OR= 3,6, IC 95% 1,1-12,8, p =0,048), body temperature (OR = 0,1, IC 95 % 0,007-0,8, p = 0,03) e Temperature/Humidity index (OR= 0,023, IC 95% 0,001-0,775, p =0,036). The results of this research are essential evidence for the structuring of embryo transfer programs in terms of considerations for the selection of recipients, their health status, environmental factors, and intrinsic/extrinsic factors in favour of the pregnancy rate and the survival of the embryo.MaestríaTeriogenología y Salud de Hatoxvi, 53 páginasapplication/pdfspaUniversidad Nacional de ColombiaBogotá - Medicina Veterinaria y de Zootecnia - Maestría en Salud y Producción AnimalFacultad de Medicina Veterinaria y de ZootecniaBogotá, ColombiaUniversidad Nacional de Colombia - Sede Bogotá630 - Agricultura y tecnologías relacionadas::636 - Producción animalBovinosEmbrión de mamíferoBovinosEmbryo, MammalianEmbriones bovinosEmbriones in-vitroTasa de preñezEnfermedades infecciosas reproductivasBovine embryosIn-vitro embryosPregnancy rateReproductive infectious diseasesEvaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitroEvaluation of the factors that influence the pregnancy rate and embryo survival in recipients of bovine embryos produced in-vitroTrabajo de grado - Maestríainfo:eu-repo/semantics/masterThesishttp://purl.org/coar/version/c_dc82b40f9837b551Texthttp://purl.org/redcol/resource_type/TMBonilla León, L., Mejía Gallego, A., Gómez Domínguez, R., Torres Londoño, M., & Uribe García, F. (2018). Viabilidad y tasa de preñez de embriones producidos in vitro a partir de semen sexado comparado con semen convencional en Bos taurus y Bos indicus. Revista de Investigaciones Veterinarias Del Perú, 29(4), 1377. https://doi.org/10.15381/rivep.v29i4.14297Chebel, R. C., Demetrio, D. G. B., & Metzger, J. (2008). Factors affecting success of embryo collection and transfer in large dairy herds. Theriogenology, 69, 98–106. https://doi.org/10.1016/j.theriogenology.2007.09.008Diniz, J. V, Ochoa, J. C., Montoya, L. M., Satrapa, R., Okuda, L. H., Pituco, E. M., … Oba, E. (2016). Immune-serological identification of infectious agents with influence on bovine embryo transfer in the north of Brazil TT - Identificación inmunoserológica de agentes infecciosos con influencia sobre la transferencia de embriones en el norte de Brasil. Archivos de Medicina Veterinaria, 48(2), 145–152. Retrieved from http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2016000200003&lang=ptFarfan Rojas, O. O., & Porras Vargas, J. L. (2013). Evaluacion de la tasa de concepcion de tres razas bovinas receptoras de embriones en el Tropico Alto. Ciencia y Agricultura Vol., 11, 77–83.Naranjo Guerrero, L. F., Rodríguez Colorado, N., & Mejía Araque, J. (2022). Prevalencia de diarrea viral bovina, neosporosis bovina, leucosis bovina enzoótica y paratuberculosis bovina en vacas de doble propósito en condiciones del trópico colombiano. Revista de Investigaciones Veterinarias Del Perú, 33(2), e20694. https://doi.org/10.15381/rivep.v33i2.20694Oyuela, L. A., & Jimenez, C. (2010). Factores que afectan la tasa de preñez en programas de transferencia de embriones. Revista de La Facultad de Medicina Veterinaria y de Zootecnia, 191–200.Oyuela, Lino Andres. (2009). FACTORES QUE AFECTAN LA TASA DE PREÑEZ EN PROGRAMAS DE TRANSFERENCIA DE EMBRIONES PRODUCIDOS IN-VITRO, EN RAZAS CEBUINAS LINO. Retrieved from http://www.bvs.hn/cu-2007/ponencias/SLD/SLD101.pdfRoper, D. A., Schrick, F. N., Edwards, J. L., Hopkins, F. M., Prado, T. M., Wilkerson, J. B., … Smith, W. B. (2018). Factors in cattle a ffecting embryo transfer pregnancies in recipient animals. Animal Reproduction Science, 199(November), 79–83. https://doi.org/10.1016/j.anireprosci.2018.11.001Alkan, H., Karaşahin, T., Dursun, Ş., Satılmış, F., Erdem, H., & Güler, M. (2020). Evaluation of the factors that affect the pregnancy rates during embryo transfer in beef heifers. Reproduction in Domestic Animals, 55(4), 421–428. https://doi.org/10.1111/rda.13623Binelli, M., Thatcher, W. W., Mattos, R., & Baruselli, P. S. (2001). Antiluteolytic strategies to improve fertility in cattle. Theriogenology, 56(9), 1451–1463. https://doi.org/10.1016/S0093-691X(01)00646-XCordeiro, A. L. L., Satrapa, R. A., Gregianini, H. A. G., Gregianini, J. T. F., Maia, G. F. N., & Landim-Alvarenga, F. C. (2020). Influence of temperature-humidity index on conception rate of Nelore embryos produced in vitro in northern Brazil. Tropical Animal Health and Production, 52(3), 1527–1532. https://doi.org/10.1007/s11250-019-02141-4de Oliveira, V. S. F., Álvarez-Garcia, G., Ortega-Mora, L. M., Borges, L. M. F., & da Silva, A. C. (2010). Abortions in bovines and Neospora caninum transmission in an embryo transfer center. Veterinary Parasitology, 173(3–4), 206–210. https://doi.org/10.1016/j.vetpar.2010.06.028Ferraz, P. A., Burnley, C., Karanja, J., Viera-neto, A., Santos, J. E. P., Chebel, R. C., & Galvão, K. N. (2016). Factors affecting the success of a large embryo transfer program in Holstein cattle in a commercial herd in the southeast region of the United States. Theriogenology, 86(7), 1834–1841. https://doi.org/10.1016/j.theriogenology.2016.05.032Guerra, A., & Álvaro. (2004). Pubertad en la hembra bovina. Sitio Argentino de Producción Animal, 1–7. Retrieved from http://www.produccion-animal.com.ar/informacion_tecnica/cria/57-pubertad_en_la_hembra_bovina.pdfHansen, P. J. (2007). Exploitation of genetic and physiological determinants of embryonic resistance to elevated temperature to improve embryonic survival in dairy cattle during heat stress. 242–249. https://doi.org/10.1016/j.theriogenology.2007.04.008Holguín, G., Montaña, D., & Valbuena, D. (2013). Corpus luteum diameter and embryo developmental stage are associated with pregnancy rate : data analysis from 17 , 521 embryo transfers from a commercial in vitro bovine embryo production program. Anim. Reprod., 10(2), 106–111.Julon, D., Burga, N., Bardales, W., & Puicón, V. (2018). Factors affecting the pregnancy rate in transfers of embryos in crossbreed Brown Swiss. MOJ Anatomy & Physiology, 5(2), 101–104. https://doi.org/10.15406/mojap.2018.05.00171Mann, G. E., Lamming, G. E., Robinson, R. S., & Wathes, D. C. (1999). The regulation of interferon-tau production and uterine hormone receptors during early pregnancy. Journal of Reproduction and Fertility. Supplement, 54, 317–328.Marzouk, A., Genedy, T., Abdel-Razek, E., Zaghloul, A., & Elbaz, H. (2020). Factors Affecting Pregnancy Rate Per Embryo Transfer of In Vivo Produced Embryos in Recipient Holstein Heifers. Journal of Current Veterinary Research, 1, 1–10.Nardone, A., Ronchi, B., Lacetera, N., Ranieri, M. S., & Bernabucci, U. (2010). Effects of climate changes on animal production and sustainability of livestock systems ☆. Livestock Science, 130(1–3), 57–69. https://doi.org/10.1016/j.livsci.2010.02.011Negrón-Pérez, V. M., Fausnacht, D. W., & Rhoads, M. L. (2019). Invited review: Management strategies capable of improving the reproductive performance of heat-stressed dairy cattle. Journal of Dairy Science, 102(12), 10695–10710. https://doi.org/10.3168/jds.2019-16718Nogueira, É., Cardoso, G. S., Romero, H., Junior, M., Dias, M., Carlos, L., … Borges, J. C. (2012). Effect of breed and corpus luteum on pregnancy rate of bovine embryo recipients. Revista Brasileira de Zootecnia, 41(2001), 2129–2133.Occhio, M. J. D., Baruselli, P. S., & Campanile, G. (2018). Influence of nutrition, body condition, and metabolic status on reproduction in female beef cattle: A review. Theriogenology. https://doi.org/10.1016/j.theriogenology.2018.11.010Ongubo, M. N., Rachuonyo, H. A., Lusweti, F. N., Kios, D. K., Kitilit, J. K., Musee, K., … Corporation, A. D. (2015). Factors affecting conception rates in cattle following embryo transfer. Uganda Journal of Agricultural Sciences, 16(1), 19–27.Perez Durand, M. G., Bejar Huaylla, T., Quispe Barriga, Y. M., Fernadez Ruelas, E. P., Flores Guillen, M. A., Delgado Castro, A., & Perez Guerra, U. H. (2022). Factores que afectan la tasa de preñez en receptoras de embriones producidos in vitro bajo condiciones de altura. Revista de Investigaciones Veterinarias Del Perú, 33(3), 1–10.Sanhueza, J. M., Heuer, C., & West, D. (2013). Contribution of Leptospira, Neospora caninum and bovine viral diarrhea virus to fetal loss of beef cattle in New Zealand. Preventive Veterinary Medicine, 112(1–2), 90–98. https://doi.org/10.1016/j.prevetmed.2013.07.009Santos, J. E. P., Rutigliano, H. M., & Sà Filho, M. F. (2009). Risk factors for resumption of postpartum estrous cycles and embryonic survival in lactating dairy cows. Animal Reproduction, 110, 207–221. https://doi.org/10.1016/j.anireprosci.2008.01.014Sartori, R., Sartor-Bergfelt, R., Mertens, S. A., Guenther, J. N., Parrish, J. J., & Wiltbank, M. C. (2010). Fertilization and Early Embryonic Development in Heifers and Lactating Cows in Summer and Lactating and Dry Cows in Winter. Journal of Dairy Science, 85(11), 2803–2812. https://doi.org/10.3168/jds.s0022-0302(02)74367-1Scenna, F. N., Hockett, M. E., Towns, T. M., Saxton, A. M., Rohrbach, N. R., Wehrman, M. E., & Schrick, F. N. (2005). Influence of a prostaglandin synthesis inhibitor administered at embryo transfer on pregnancy rates of recipient cows. 78, 38–45. https://doi.org/10.1016/j.prostaglandins.2005.02.003Siqueira, L. G. B., Torres, C. A. A., Souza, E. D., Monteiro Jr., P. L. J., Arashiro, E. K. ., Camargo, L. S. A., … Viana, J. H. M. (2009). Pregnancy rates and corpus luteum – related factors affecting pregnancy establishment in bovine recipients synchronized for fixed-time embryo transfer. Theriogenology, 72, 949–958. https://doi.org/10.1016/j.theriogenology.2009.06.013Vandaele, L. (2010). INTRINSIC FACTORS AFFECTING APOPTOSIS IN BOVINE IN VITRO PRODUCED EMBRYOS. In Universiteit Gent. https://doi.org/10.1016/j.theriogenology.2015.10.036Vasquez Ch., Y., & Amilcar Bò., G. (2017). Evaluacion De Los Diferentes Factores Que Afectan La Reproduccion Bovina Con Relacion a Bienestar Animal (Instituto de Reproduccion Animal Cordoba IRAC). Retrieved from https://rdu.unc.edu.ar/bitstream/handle/11086/4859/Yoo, H. S. (2010). Infectious Causes of Reproductive Disorders in Cattle. Journal of Reproduction and Development, 56, 53–60.Viana, J., IETS Data Retrieval Committee in Embryo Technology Newsletter. 2021, International Embryo & Technology Society.Alkan, H., et al., Evaluation of the factors that affect the pregnancy rates during embryo transfer in beef heifers. Reprod Domest Anim, 2020. 55(4): p. 421-428.Pontes, J.H.F., et al., Ovum pick up, in vitro embryo production, and pregnancy rates from a large-scale commercial program using Nelore cattle (Bos indicus) donors. Theriogenology, 2011. 75(9): p. 1640-1646.Looney, C.R., et al., Improving fertility in beef cow recipients. Theriogenology, 2006. 65(1): p. 201-9D'Occhio, M.J., P.S. Baruselli, and G. Campanile, Influence of nutrition, body condition, and metabolic status on reproduction in female beef cattle: A review. Theriogenology, 2019. 125: p. 277-284.Mann, G.E., et al., The regulation of interferon-tau production and uterine hormone receptors during early pregnancy. J Reprod Fertil Suppl, 1999. 54: p. 317-28.Binelli, M., et al., Antiluteolytic strategies to improve fertility in cattle. Theriogenology, 2001. 56(9): p. 1451-1463.Roper, D.A., et al., Factors in cattle affecting embryo transfer pregnancies in recipient animals. Anim Reprod Sci, 2018. 199: p. 79-83.Chebel, R.C., D.G. Demétrio, and J. Metzger, Factors affecting the success of embryo collection and transfer in large dairy herds. Theriogenology, 2008. 69(1): p. 98-106.Sánchez, J.M., et al., Embryonic maternal interaction in cattle and its relationship with fertility. Reprod Domest Anim, 2018. 53 Suppl 2: p. 20-27.Givens, D.M. and M.S.D. Marley, Infectious causes of embryonic and fetal mortality. Theriogenology, 2008. 70(3): p. 270-285.Forar, A.L., et al., Fetal loss frequency in ten Holstein dairy herds. Theriogenology, 1996. 45(8): p. 1505-1513.Kendall, P.E. and J.R. Webster, Season and physiological status affects the circadian body temperature rhythm of dairy cows. Livestock Science, 2009. 125(2): p. 155-160.Lemeshow, S. and D.W. Hosmer, JR., A Review of Goddess of fit Statistics for use in the development of Logistic Regression Models American Journal of Epidemiology, 1982. 115(1): p. 92-106.Bielanski, A., et al., Transmission of bovine viral diarrhea virus (BVDV) via in vitro-fertilized embryos to recipients, but not to their offspring. Theriogenology, 2009. 71(3): p. 499-508.Baillargeon, P., et al., Evaluation of the embryo transfer procedure proposed by the International Embryo Transfer Society as a method of controlling vertical transmission of Neospora caninum in cattle. J Am Vet Med Assoc, 2001. 218(11): p. 1803-6.Shabbir, M.Z., et al., Seroprevalence of Neospora caninum and Brucella abortus in dairy cattle herds with high abortion rates. J Parasitol, 2011. 97(4): p. 740-2.Walz, P.H., et al., Evaluation of reproductive protection against bovine viral diarrhea virus and bovine herpesvirus-1 afforded by annual revaccination with modified-live viral or combination modified-live/killed viral vaccines after primary vaccination with the modified-live viral vaccine. Vaccine, 2017. 35(7): p. 1046-1054.Pereira, M.H., et al., Effects of vaccination against reproductive diseases on reproductive performance of lactating dairy cows submitted to AI. Anim Reprod Sci, 2013. 137(3-4): p. 156-62.Aono, F.H., et al., Effects of vaccination against reproductive diseases on reproductive performance of beef cows submitted to fixed-timed AI in Brazilian cow-calf operations. Theriogenology, 2013. 79(2): p. 242-8.Edelhoff, I.N.F., et al., Inflammatory diseases in dairy cows: Risk factors and associations with pregnancy after embryo transfer. J Dairy Sci, 2020. 103(12): p. 11970-11987.Banos, G., et al., Identification of immune traits correlated with dairy cow health, reproduction, and productivity. PLoS One, 2013. 8(6): p. e65766.Moraes, J.G.N., et al., Uterine influences on conceptus development in fertility-classified animals. 2018. 115(8): p. E1749-E1758.Sheldon, I.M., et al., Uterine diseases in cattle after parturition. Vet J, 2008. 176(1): p. 115-21.Dahl, M.O., et al., Evidence that mastitis can cause pregnancy loss in dairy cows: A systematic review of observational studies. Journal of Dairy Science, 2017. 100(10): p. 8322-8329.Rodríguez-Lecompte, J.C., et al., Evaluation of the systemic innate immune response and metabolic alterations of nonlactating cows with diet-induced subacute ruminal acidosis. J Dairy Sci, 2014. 97(12): p. 7777-87.Mohammad, S. and C. Thiemermann, Role of Metabolic Endotoxemia in Systemic Inflammation and Potential Interventions. Front Immunol, 2020. 11: p. 594150.Baumgard, L.H. and R.P. Rhoads, Jr., Effects of heat stress on postabsorptive metabolism and energetics. Annu Rev Anim Biosci, 2013. 1: p. 311-37.Schrödl, W., et al., Acute phase proteins as promising biomarkers: Perspectives and limitations for human and veterinary medicine. Proteomics Clin Appl, 2016. 10(11): p. 1077-1092.Edelhoff, I.N.F., et al., Inflammatory diseases in dairy cows: Risk factors and associations with pregnancy after embryo transfer. Journal of Dairy Science, 2020. 103(12): p. 11970-11987.Yasuda, K. and E. Kuroda, Role of eosinophils in protective immunity against secondary nematode infections. Immunological Medicine, 2019. 42(4): p. 148-155.Wiltbank, M., A. Gümen, and R.J.T. Sartori, Physiological classification of anovulatory conditions in cattle. 2002. 57(1): p. 21-52.Walsh, R., et al., Prevalence and risk factors for the postpartum anovulatory condition in dairy cows. 2007. 90(1): p. 315-324.Kadokawa, H., D. Blache, and G.J.J.o.d.s. Martin, Plasma leptin concentrations correlate with luteinizing hormone secretion in early postpartum Holstein cows. 2006. 89(8): p. 3020-3027.Wathes, D.C., et al., Negative energy balance alters global gene expression and immune responses in the uterus of postpartum dairy cows. 2009. 39(1): p. 1-13.Ribeiro, E., et al., Conceptus development and transcriptome at preimplantation stages in lactating dairy cows of distinct genetic groups and estrous cyclic statuses. 2016. 99(6): p. 4761-4777.VanRaden, P.M. and R.H. Miller, Effects of nonadditive genetic interactions, inbreeding, and recessive defects on embryo and fetal loss by seventy days. J Dairy Sci, 2006. 89(7): p. 2716-21.Baruselli, P.S., et al., Use of embryo transfer to alleviate infertility caused by heat stress. Theriogenology, 2020. 155: p. 1-11.Mikkola, M., M. Andersson, and J. Taponen, Transfer of cattle embryos produced with sex-sorted semen results in impaired pregnancy rate and increased male calf mortality. Theriogenology, 2015. 84(7): p. 1118-1122.Pontes, J.H.F., et al., Large-scale in vitro embryo production and pregnancy rates from Bos taurus, Bos indicus, and indicus-Taurus dairy cows using sexed sperm. Theriogenology, 2010. 74(8): p. 1349-1355.Chenoweth, P.J., Influence of the male on embryo quality. Theriogenology, 2007. 68(3): p. 308-15.Zhang, S., et al., The effect of prostaglandin E2 receptor (PTGER2) activation on growth factor expression and cell proliferation in bovine endometrial explants. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2017. 122: p. 16-23.Sakai, S., et al., Heat stress influences the attenuation of prostaglandin synthesis by interferon tau in bovine endometrial cells. Theriogenology, 2021. 165: p. 52-58.Nanas, I., et al., Early embryo losses, progesterone, and pregnancy-associated glycoproteins levels during summer heat stress in dairy cows. Journal of Thermal Biology, 2021. 98: p. 102951.Dorniak, P., F. Bazer, and T.J.J.o.a.s. Spencer, Physiology and Endocrinology Symposium: biological role of interferon tau in endometrial function and conceptus elongation. 2013. 91(4): p. 1627-1638.Kornmatitsuk, B., et al., Different types of postpartum luteal activity affected by the exposure of heat stress and subsequent reproductive performance in Holstein lactating cows. 2008. 43(5): p. 515-519.Pegorer, M.F., et al., Influence of sire and sire breed (Gyr versus Holstein) on the establishment of pregnancy and embryonic loss in lactating Holstein cows during summer heat stress. Theriogenology, 2007. 67(4): p. 692-697.Silke, V., et al., Extent, pattern and factors associated with late embryonic loss in dairy cows. Animal Reproduction Science, 2002. 71(1): p. 1-12.Libonati, H.A., et al., Leptospirosis is strongly associated with estrus repetition on cattle. Trop Anim Health Prod, 2018. 50(7): p. 1625-1629.Givens, M.D., J.A. Gard, and D.A. Stringfellow, Relative risks and approaches to biosecurity in the use of embryo technologies in livestock. Theriogenology, 2007. 68(3): p. 298-307.Chi, J., et al., Management factors related to seroprevalences to the bovine viral diarrhea virus, bovine-leukosis virus, Mycobacterium avium subspecies paratuberculosis, and Neospora caninum in dairy herds in the Canadian Maritimes. Preventive Veterinary Medicine, 2002. 55(1): p. 57-68.De Rensis, F., et al., Causes of declining fertility in dairy cows during the warm season. Theriogenology, 2017. 91: p. 145-153.Gendelman, M. and Z. Roth, In vivo vs. in vitro models for studying the effects of elevated temperature on the GV-stage oocyte, subsequent developmental competence, and gene expression. Anim Reprod Sci, 2012. 134(3-4): p. 125-34.Hansen, P.J., et al., Adverse impact of heat stress on embryo production: causes and strategies for mitigation. Theriogenology, 2001. 55(1): p. 91-103.Abdalla, H., et al., Maternal and non-maternal factors associated with late embryonic and early fetal losses in dairy cows. Theriogenology, 2017. 100: p. 16-23.Diniz, J.V.A., et al., Fertility traits of recipient cows raised in the Amazon biome. Livestock Science, 2020. 240: p. 104147.Cooke, R.F., et al., Effects of acclimation to human interaction on performance, temperament, physiological responses, and pregnancy rates of Brahman-crossbred cows. J Anim Sci, 2009. 87(12): p. 4125-32.Dobson, H., et al., Is stress all that important? Theriogenology, 2001. 55(1): p. 65-73.ANALISIS DE LOS FACTORS GENETICOS, SANITARIOS Y MEDIOAMBIENTALES QUE AFECTANLAS TASAS DE PREÑEZ A PARTIR DE EMBRIONES IN VITRO EN EL DEPARTAMENTO DE CUNDINAMARCAEstudiantesInvestigadoresMaestrosLICENSElicense.txtlicense.txttext/plain; charset=utf-85879https://repositorio.unal.edu.co/bitstream/unal/84783/1/license.txteb34b1cf90b7e1103fc9dfd26be24b4aMD51ORIGINAL1136886008.2023.pdf1136886008.2023.pdfTesis de Maestría en Salud y Producción Animalapplication/pdf547340https://repositorio.unal.edu.co/bitstream/unal/84783/3/1136886008.2023.pdf755fb653b63b7671127f4119a0b9597bMD53THUMBNAIL1136886008.2023.pdf.jpg1136886008.2023.pdf.jpgGenerated Thumbnailimage/jpeg4581https://repositorio.unal.edu.co/bitstream/unal/84783/4/1136886008.2023.pdf.jpgc00cff6c8cd589182f4b9702a7fa1054MD54unal/84783oai:repositorio.unal.edu.co:unal/847832023-10-06 23:03:55.208Repositorio Institucional Universidad Nacional de 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Evaluación de los factores que influyen sobre la tasa de preñez y la supervivencia embrionaria en receptoras de embriones bovinos producidos in-vitro

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